A New Approach to the Stimulation of the Body’s Defense Systems with Low Radiation Doses

2020 ◽  
Vol 10 (6) ◽  
pp. 475-482
Author(s):  
V. F. Mikhailov ◽  
G. D. Zasukhina
Keyword(s):  
Radiation Doses ◽  
New Approach ◽  
Defense Systems ◽  
Low Radiation Doses ◽  
Stimulation Of

Effect of low radiation doses on microbe population in space stations

2002 ◽  
Vol 8 (5-6) ◽  
pp. 58-61
Author(s):  
V.V. Tsetlin ◽  
◽  
E.A. Deshevaya ◽  
N.D. Novikova ◽  
N.A. Polikarpov ◽  
...  
Keyword(s):  
Radiation Doses ◽  
Low Radiation Doses ◽  
Microbe Population

Eye protection in interventional procedures

2021 ◽  
Vol 94 (1126) ◽  
pp. 20210436 ◽  
Author(s):  
Beth A. Schueler ◽  
Kenneth A Fetterly
Keyword(s):  
Interventional Procedures ◽  
Eye Lens ◽  
Radiation Doses ◽  
Radiation Induced ◽  
Individual Actions ◽  
Dose Measurements ◽  
Dose Levels ◽  
Patient Radiation Dose ◽  
Low Radiation Doses

Data suggest that radiation-induced cataracts may form without a threshold and at low-radiation doses. Staff involved in interventional radiology and cardiology fluoroscopy-guided procedures have the potential to be exposed to radiation levels that may lead to eye lens injury and the occurrence of opacifications have been reported. Estimates of lens dose for various fluoroscopy procedures and predicted annual dosages have been provided in numerous publications. Available tools for eye lens radiation protection include accessory shields, drapes and glasses. While some tools are valuable, others provide limited protection to the eye. Reducing patient radiation dose will also reduce occupational exposure. Significant variability in reported dose measurements indicate dose levels are highly dependent on individual actions and exposure reduction is possible. Further follow-up studies of staff lens opacification are recommended along with eye lens dose measurements under current clinical practice conditions.

scholarly journals The photocarcinogenicity of anthracence: photochemical binding to deoxyribonucleic acid in tissue culture

1975 ◽  
Vol 149 (1) ◽  
pp. 289-291 ◽  
Author(s):  
G M Blackburn ◽  
P E Taussig
Keyword(s):  
Molecular Weight ◽  
Tissue Culture ◽  
High Molecular Weight ◽  
Deoxyribonucleic Acid ◽  
Radiation Doses ◽  
Mammalian Tissue ◽  
Hydrocarbon Molecule ◽  
High Radiation ◽  
High Molecular Weight Dna ◽  
Low Radiation Doses

Anthracene becomes covalently bound to high-molecular-weight DNA in mammalian tissue culture as a result of irradiation at 365 nm after the incubation of cells with the hydrocarbon. At high radiation doses, the extent of binding exceeds one hydrocarbon molecule per 103 bases, and is lethal. At low radiation doses, much decreased binding is observed, but a majority of cells remain viable and can be recultured.

scholarly journals Lack of DNA Damage Response at Low Radiation Doses in Adult Stem Cells Contributes to Organ Dysfunction

2018 ◽  
Vol 24 (24) ◽  
pp. 6583-6593 ◽  
Author(s):  
Peter W. Nagle ◽  
Nynke A. Hosper ◽  
Lara Barazzuol ◽  
Anne L. Jellema ◽  
Mirjam Baanstra ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dna Damage ◽  
Organ Dysfunction ◽  
Dna Damage Response ◽  
Adult Stem Cells ◽  
Radiation Doses ◽  
Damage Response ◽  
Low Radiation Doses

scholarly journals Modulation of gut mucosal biofilms

2005 ◽  
Vol 93 (S1) ◽  
pp. S35-S40 ◽  
Author(s):  
Brigitta Kleessen ◽  
Michael Blaut
Keyword(s):  
Colonic Mucosa ◽  
Mucosal Barrier ◽  
Mucus Layer ◽  
Faecal Flora ◽  
New Approach ◽  
Serovar Typhimurium ◽  
Health Promoting ◽  
Gut Mucosal Barrier ◽  
Induced Changes ◽  
Stimulation Of

Non-digestible inulin-type fructans, such as oligofructose and high-molecular-weight inulin, have been shown to have the ability to alter the intestinal microbiota composition in such a way that members of the microbial community, generally considered as health-promoting, are stimulated. Bifidobacteria and lactobacilli are the most frequently targeted organisms. Less information exists on effects of inulin-type fructans on the composition, metabolism and healthrelated significance of bacteria at or near the mucosa surface or in the mucus layer forming mucosa-associated biofilms. Using rats inoculated with a human faecal flora as an experimental model we have found that inulin-type fructans in the diet modulated the gut microbiota by stimulation of mucosa-associated bifidobacteria as well as by partial reduction of pathogenicSalmonella enterica subsp. entericaserovar Typhimurium and thereby benefit health. In addition to changes in mucosal biofilms, inulin-type fructans also induced changes in the colonic mucosa stimulating proliferation in the crypts, increasing the release of mucins, and altering the profile of mucin components in the goblet cells and epithelial mucus layer. These results indicate that inulin-type fructans may stabilise the gut mucosal barrier. Dietary supplementation with these prebiotics could offer a new approach to supporting the barrier function of the mucosa.

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