META-ANALYSIS OF PHYTOGENIC ADDITIVES FOR BROILERS

Author(s):  
Gustavo do Valle Polycarpo ◽  
Gabrieli Andressa de Lima ◽  
Thaís de Souza Ávida ◽  
Fábio Sampaio Rosas ◽  
Valquiria Cação Cruz-Polycarpo ◽  
...  

Phytogenic additives have been studied intensively in broiler chickens’ production to substitute growth-promoting antibiotics. However, the comprehensive literature on this topic makes it difficult to understand overall results because there are a noticeable number of studies with conflicting conclusions. While several research studies have shown that phytogenic additives may increment broiler chicken’s performance, others make the opposite evident. This study aimed to organize and understand information through meta-analysis considering a great number of publications and the factors that may interfere in the results of phytogenic additives, evaluating whether phytogenic additives can be used as a performance-enhancing additive for broilers, comparing with the effectiveness of growth-promoting antibiotics. The main factor that interferes in the evaluation of phytogenic additives is the microbiological challenge. Phytogenic additives improved average daily gain (ADG) (P < 0.001) and feed conversion (P < 0.001) regardless of microbiological challenge; however, they were worse compared to antibiotics under higher challenge (P < 0.020). A meta-regression of ADG in function of average daily feed intake confirmed that phytogenic additives increased the feed efficiency of broilers, but with less effectiveness than antibiotics. The blends of phytogenic additives increased the ADG in relation to the isolated use of only one phytogenic additive.

Animals ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2839
Author(s):  
Anthony Pokoo-Aikins ◽  
Jennifer Rumsey Timmons ◽  
Byungrok Rok Min ◽  
William Robert Lee ◽  
Samuel Njoroge Mwangi ◽  
...  

This study was designed to evaluate the effects of dietary supplemental DL-methionine (MET) on live performance and meat yield for broilers raised to a common weight. A total of 1552 one-day old Ross 708, sexed broilers were randomly distributed to 32 pens resulting in eight treatments (TRT) of four replicates with 44 male or 53 female/pen. A randomized complete block with a 2 × 4 (sex × 4 MET levels 0, 0.5, 1, and 2 g/kg) factorial arrangement of TRT was used. A common weight of 2400 g was approached by day 46 (1 and 2 g MET/kg feed) and day 48 (0 and 0.5 g MET/kg feed). Supplementation of MET at 1, and 2 g/kg had a lower (p < 0.01) feed conversion ratio (FCR) at day 46/48 than broilers fed 0.5 g MET/kg. Broilers without supplemental MET had the worst (p < 0.01) feed conversion and average daily gain (ADG) at day 46/48. Birds fed 0 g MET/kg of feed had lower (p < 0.05) whole eviscerated carcass without giblets (WOG), yield than birds fed 2 g MET/kg of feed. Additionally, birds fed 0 g MET/kg of feed had lower (p < 0.05) breast fillet and tender percent yields than birds fed supplemental MET. Elimination of MET from organic broiler diets resulted in reduced ADG, breast fillet yield and feed efficiency of meat yield of broilers raised to day 46/48. Reduction in MET supplementation below current levels reduced the efficiency of meat production of organic broilers raised to day 46/48.


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 472-472
Author(s):  
Benjamin Bass ◽  
Stacie Crowder ◽  
Murali Raghavendra Rao

Abstract Ambitine Feed Additive (AMB), a proprietary blend of phytogenics and acidifiers (PMI, Arden Hills, MN), is formulated to help mitigate late finishing stress in pigs. Several studies using AMB in the late finishing period resulted in improved pig performance. A meta-analytic method used 13 studies (3 studies with ractopamine and 10 studies without) to determine the overall impact of AMB on average daily gain, average daily feed intake, and feed conversion. The combined data were considered a randomized complete block design. Analysis of variance was completed using the GLIMMIX procedure of SAS (9.4; Cary, NC) and least squares means were compared using Fisher’s least significant difference (P &lt; 0.05). In the analysis of 10 studies with no added ractopamine (73 pens/treatment of 5 to 10 pigs/pen and 48 pens/treatment of 17 to 20 pigs/pen), pigs provided AMB had higher average daily gain (0.90 vs 0.86 kg/d; P &lt; 0.05), increased average daily feed intake (2.99 vs 2.94 kg/d; P &lt; 0.05), and improved feed efficiency (0.30 vs 0.29 kg gain/kg feed intake; P &lt; 0.05) compared to pigs fed control diets. Additionally, when pigs were provided AMB in addition to ractopamine (3 studies; 33 pens/treatment of 18 to 22 pigs/pen), average daily gain was increased 4.7% (1.206 vs 1.152 kg/d; P &lt; 0.05) and feed efficiency was improved 5.3% (0.40 vs 0.38 kg gain/kg feed intake; P &lt; 0.05) compared to pigs provided only ractopamine, with no difference in feed intake. Pigs provided AMB in addition to ractopamine had increased hot carcass weight and dressing percentage (P &lt; 0.05) compared to those provided ractopamine alone. In conclusion, providing AMB to pigs in late finishing improved ADG and feed efficiency and the improvement was maintained when ractopamine was included in the diets.


2016 ◽  
Vol 37 (2) ◽  
pp. 977
Author(s):  
João Vinícius Barbosa Roberto ◽  
Bonifácio Benicio de Souza ◽  
Gabriel Jorge Carneiro de Oliveira  ◽  
Jaime Miguel de Araujo Filho ◽  
Thaiz Lamy Alves Ribeiro ◽  
...  

This study evaluated food intake and productive performance of crossbred (½ Santa Inês x ½ dorper) lambs supplemented with different levels of faveleira (Cnidoscolus quercifolius Pohl) fodder salt. Thirty male sheep fed tifton grass hay, water, and faveleira fodder salt were randomly allocated into five treatments with six replicates each. The treatments consisted of diets with different inclusion levels of faveleira hay in the fodder salt composition: Treatment 1 (1% mineral salt + 99% faveleira hay), Treatment 2 (3% mineral salt + 97% faveleira hay), Treatment 3 (5% mineral salt + 95% faveleira hay), Treatment 4 (7% mineral salt + 93% faveleira hay), and Treatment 5 (Control - 100% mineral salt). Intake of dry matter, tifton hay and water, average daily gain, feed conversion, and feed efficiency were not affected by fodder salt supplementation (P > 0.05). There was a significant difference (P < 0.05) in fodder salt intake between Treatments 4 and 5, and daily intake was higher in animals submitted to Treatment 4 (61.0 g day-1). Mineral salt intake increased significantly with increasing mineral salt levels in the diet. However, no significant difference was observed in average daily gain across treatments, indicating that faveleira hay, even in small quantities, and tifton hay were able to meet the nutritional requirements of animals to support a good average daily gain. The inclusion of up to 99% faveleira hay in fodder salt formulations did not affect voluntary intake of forage, water and dry matter, average daily gain, feed conversion, and feed efficiency. Lambs supplemented with faveleira fodder salt had average daily gains within the optimal range for slaughter and high feed conversion and feed efficiency values. Faveleira was shown to be an effective supplementary feed alternative in sheep.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 175-176
Author(s):  
Benjamin Bass ◽  
Stacie Crowder ◽  
Terry Weeden ◽  
Murali Raghavendra Rao ◽  
Brenda de Rodas ◽  
...  

Abstract OutPace® Feed Additive (OP), contains a carefully researched blend of activated medium chain fatty acids (MCFAs; PMI, Arden Hills, MN), formulated to help mitigate the effects of stress in nursery pigs. Several studies using OP in both late and full nursery periods resulted in improved pig performance. A meta-analysis using 9 studies (4 studies during late nursery [15 to 26.8 kg BW] and 5 studies during the full nursery [5.9 to 25.4 kg]) was done to determine the impact of OP (included at 0.25% Phase 1 and 2; 0.125% Phase 3) on average daily gain, average daily feed intake, and feed conversion. The combined data was considered a randomized complete block design. Analysis of variance was completed with mixed models using the GLIMMIX procedure of SAS (SAS 9.4, SAS Institute Inc., Cary, NC) and least squares means were compared using Fisher’s least significant difference (P &lt; 0.05). In the analysis of 5 studies conducted in late nursery (45 pens/treatment of 6 to 20 pigs/pen), pigs provided OP had higher average daily gain (0.67 vs 0.63 kg/d; P &lt; 0.05), increased average daily feed intake (0.99 vs 0.97 kg/d; P &lt; 0.05), and improved feed efficiency (0.67 vs 0.65 kg gain/kg feed intake; P &lt; 0.05) compared to pigs fed control diets. Additionally, when pigs were provided OP throughout the nursery period (20 pens/treatment of 7 to 20 pigs/pen), average daily gain was increased 6.1% (0.48 vs 0.45 kg/d; P &lt; 0.05), average daily feed intake tended to be increased 2.2% (0.62 vs 0.61 kg/d; P &lt; 0.1), and feed efficiency was improved 2.7% (0.76 vs 0.74 kg gain/kg feed intake; P &lt; 0.05) compared to pigs provided control diets. In conclusion, providing OP to pigs during the nursery period improved ADG and feed efficiency.


2021 ◽  
Vol 51 (4) ◽  
pp. 477-487
Author(s):  
S. Sadarman ◽  
E. Erwan ◽  
A. Irawan ◽  
M.M. Sholikin ◽  
R. Solfaine ◽  
...  

A meta-analysis was conducted to examine the effect of supplementing the diet of broiler chickens with propolis on growth, bacterial population of the intestine, antiviral serum concentration, intestinal morphology, and digestive enzyme activities in broiler chickens. Forty peer-reviewed articles that had been published between 2003 and 2019 were identified using the PRISMA protocol and included in the study. Data were analysed with mixed model methodology, in which the studies were considered random effects, whereas the level of supplemental propolis was considered a fixed effect. Responses to propolis supplementation in bodyweight (BW) and average daily gain (ADG) were quadratic, but average daily feed intake (ADFI) was not affected. Propolis supplementation improved feed conversion ratio (FCR) significantly as a linear function of the level of supplement. The optimum level of supplementation was between 256 and 262 mg/kg feed and produced maximum ADG and final BW. There was a tendency for mortality to decrease because of propolis supplementation. Propolis had no detectable effect on serum antiviral concentration, intestinal bacterial population or intestinal morphology. Among digestive enzymes, only sucrase increased linearly as propolis was increased. Thus, supplementation with propolis increased the growth performance of broiler chickens positively and the effect was dose dependent. This may have been partly because of an improvement in sucrase activity and other factors related to the nutritional content of propolis. Future study to evaluate specific bioactive compounds of propolis is therefore warranted.


2017 ◽  
Vol 9 (4) ◽  
pp. 21 ◽  
Author(s):  
Everton Dezordi Sartori ◽  
Maria Eugênia Andrighetto Canozzi ◽  
Daniele Zago ◽  
Ênio Rosa Prates ◽  
João Pedro Velho ◽  
...  

This meta-analysis evaluates the effects of yeast supplementation (Saccharomyces cerevisiae) on dry matter intake (DMI) and average daily gain (ADG) in beef cattle. The inclusion criteria were complete and randomized trials and supplementation with yeast S. cerevisiae versus no supplementation to measure DMI or ADG. Data were extracted from relevant papers via pre-defined protocols. A meta-analysis of random effects was conducted for each indicator separately including the mean of the control and treated groups. The results were presented with the pooled mean difference (MD), 95% of confidence interval, and I² (percentage of total variation between studies that is due to heterogeneity rather than chance). A total of 12 publications reporting 22 trials conducted in 1,161 cattle were analysed. The heterogeneity between studies was high and ranged from 92 to 99%. No effects were observed in ADG with the inclusion of yeast in the diet (MD = -2.849 g/day, p = 0.492). However, there was a reduction in the DMI (MD = -0.885 kg/day; p = 0.023) despite the high heterogeneity among studies (I2 = 92.4%; p < 0.001). The ADG increased when the forage level in the diet was between 30 and 50% (MD = 641.08 g/day; p = 0.001) and decreased when the level range from 51 to 75% (MD = -2.90 g/day; p < 0.001). In over 60% of the Neutral Detergent Fibre, the use of yeast in the diet decreased the ADG by 406.94 g/day (p = 0.034). Feedlot animals showed a reduction in the DMI (MD = -0.97 kg/day; p = 0.019) if supplemented with yeast. Supplementation with S. cerevisiae in the diet of beef cattle had no effect on ADG; however, it does improve the feed conversion due to the reduction in DMI.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 18-18
Author(s):  
Maroua Zouaoui ◽  
Aude Simongiovanni ◽  
Marie-Pierre Létourneau-Montminy

Abstract Branched chain amino acids (BCAA), valine (Val), isoleucine (Ile) and leucine (Leu) share the same metabolic pathways. An excess of Leu stimulates the catabolism of Val and Ile that may lead to a decrease in piglet growth performance. The objective of this study is to quantify the response of piglets to dietary Val and the influence of Leu and Ile on this response through a meta-analysis approach. A total of 16 articles published between 2001 and 2018, including 23 experiments and 126 treatments were used. Multiple regression models were fitted with the MIXED procedure of Minitab software with the random effect of the experiment. The Y variables were Average Daily Gain (ADG), Average Daily Feed Intake (ADFI) and Feed Conversion Ratio (FCR). The main X variable was the Standardized Ileal Digestible Val (ValSID) and the other ones were Leu (LeuSID) and Ile (IleSID). The response of ADG, ADFI and FCR to ValSID was curvilinear (P&lt; 0.001: ADG, R2 = 0.93%; ADFI, R2= 0.97%; FCR, R2=0.93%). Results showed that increasing dietary LeuSID reduced ADG and ADFI (P&lt; 0.05) but also that the response of piglets to ValSID was stronger in high LeuSID diet (P &lt; 0.05; Interaction ValSIDxLeuSID; ADG and ADFI). Based on these models, increasing dietary ValSID from 7 to 8.5g/kg generates in wheat-based diets (10 g /kg of LeuSID) an improvement of ADG of 4.7% and ADFI of 2.5% compared to 7.4% for ADG and 5.2% for ADFI in corn-based diets (14 g/ kg of LeuSID). The response of ADG, ADFI and FCR to ValSID was not modified by IleSID. This study showed that ADG, ADFI and FCR are improved with increasing dietary Val and this effect was modulated by dietary Leu content except for FCR. Results can help piglet nutritionists to optimize dietary Val levels based on other BCAA content.


2020 ◽  
Vol 98 (6) ◽  
Author(s):  
Fiona M O’ Meara ◽  
Gillian E Gardiner ◽  
John V O’ Doherty ◽  
David Clarke ◽  
Wayne Cummins ◽  
...  

Abstract Fermented liquid feeding has proved beneficial for weaner pigs; however, there is limited research on its effect on the growth and feed conversion efficiency (FCE) of grow-finisher pigs. Microbial decarboxylation of amino acids is associated with whole diet fermentation, while wet/dry and liquid feeding reportedly improve growth compared with dry feeding. The objective of this study was to determine the effect of wet/dry feeding and fresh, fermented whole diet, and fermented cereal liquid feeding on pig growth, feed efficiency, and carcass quality in grow-finisher pigs. Pigs were allocated to one of four dietary treatments in two experiments: 1) Single-space wet/dry feeders (WET/DRY), 2) Fresh liquid feeding (FRESH), 3) Fermented cereal liquid feeding where the cereal fraction (38% barley, 40% wheat) of the diet was fermented prior to feeding (FERM-CER), and 4) Fermented whole diet liquid feeding where the whole diet was fermented prior to feeding (FERM-WH). In exp. 1, pigs were fed the experimental diets for 68 d prior to slaughter (29.8 kg ± 0.92 SE to 102.3 kg ± 0.76 SE). Overall, average daily gain (ADG) was 1,094, 1,088, 1,110, and 955 g/d (SE = 13.0; P &lt; 0.001) and FCE was 2.26, 2.37, 2.40, and 2.88 (SE = 0.031; P &lt; 0.001) for treatments one through four, respectively. Pigs fed FERM-WH were lighter at slaughter than pigs fed the other three treatments (P &lt; 0.001). In exp. 2, pigs were on treatment for 26 d prior to slaughter (85.3 kg ± 1.69 SE to 117.5 kg ± 0.72 SE). Overall, ADG in exp. 2 was 1,103, 1,217, 1,284, and 1,140 g/d (SE = 27.9; P &lt; 0.01) and FCE was 2.78, 2.99, 2.95, and 3.09 g/g (SE = 0.071; P = 0.05), for treatments one through four, respectively. There were no significant differences observed between treatments for apparent total tract digestibility of dry matter, organic matter, nitrogen, gross energy, or ash. Higher lactic acid bacteria counts and lower Enterobacteriaceae counts and pH were observed in FERM-CER and FERM-WH compared with WET/DRY and FRESH. Ethanol concentrations were almost 4-fold higher in FERM-CER troughs than FRESH troughs and 5-fold higher in FERM-WH than FRESH troughs. To conclude, FERM-WH resulted in poorer growth and FCE compared with WET/DRY, FRESH, and FERM-CER, probably due to amino acid degradation and a loss in gross energy found in FERM-WH.


2017 ◽  
Vol 5 (1) ◽  
pp. 23 ◽  
Author(s):  
Isti Astuti

<div class="Section1"><p><em>The obyective of this experiment was to study the effect of substitution of soybean meal with local sesame meal on performance and protein effisiency ratio of broiler chicken. One hundred of broiler chickens strain Lohman were allocated in Completely Randomized Design with five replication and four chicken of each. The treatments were  P0 :  100% BK+ 0% BWL ;  P1 :  90% BK+ 10% BWL ;  P2 ; 80% BK+ 20% BWL;   P3  :  70% BK+ 30 BWL and  P4 :  60% BK+ 40% BWL. Variable measured were feed consumption,average daily gain, feed conversion and protein efficiency ratio. Data were analyzed with analysis of variance (ANOVA). </em></p><p><em>The result of this research indicated  that treatments were not significant effect to the all variables. Average feed consumption (g/head/d)  of: (92,76; 90,13; 90,87; 87,10 dan</em></p></div><em><br clear="all" /> </em><p><em>89,31) ; average daily gain (g/head/d) of : (47,16; 45,99; 47,03; 45,46 dan 45,76);  average of feed conversion of : ( 1,95;  1,97; 1,93;  1,96 dan  1,95) and protein efficiency ratio  of : (2,31;  2,27;  2,25;  2,31; dan 2,28)  for P0,  P1,  P2, P3 and P4, respectively. It was concluded that 40% of soybean meal could  be substituted with local sesame meal in diet of broiler  that reared up to 42 days of age.</em></p><p align="center"><em> </em></p><p><em>Key words:   soybean meal, local  sesame meal, performance, efficiency protein, broiler</em><em></em></p>


2022 ◽  
Vol 951 (1) ◽  
pp. 012030
Author(s):  
Y Hardiyanto ◽  
A Jayanegara ◽  
R Mutia ◽  
S Nofyangtri

Abstract Guanidinoacetic acid (GAA) is formed by the arginine and glycine that are catalysed by arginine:glycine amidinotransferase in the kidney. In the liver, GAA is methylated by s-adenosyl methionine and converted to creatine, then deposited into muscle as energy supply. This meta-analysis was done by integrating 20 articles from various journals. Supplementation doses ranged from 0 to 8000 ppm/kg feed. The mixed model methodology was employed with GAA level and broiler strain as fixed effects and studies as random effects. The results showed that increasing GAA level improved average daily gain day 0-21 and reduced feed conversion ratio day 0-35 (P<0.05). A higher GAA also accompanied by decreasing relative liver weight (P<0.05). GAA supplementation did not affect average daily feed intake and percentage of carcass traits (carcass, legs, breast, wings, drum, thigh) and other parameters such as abdominal fat, gizzard, heart, bursa, thymus and spleen (P>0.05). It was concluded that supplementation of GAA improved the performance of broilers.


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