USING FUNCTIONAL NEAR-INFRARED SPECTROSCOPY TO MEASURE COGNITIVE FUNCTION: WHEN WILL IT BECOME AN ACCEPTED CLINICAL TOOL FOR COGNITIVE AGING AND PRODROMAL DEMENTIA SCREENING?

2011 ◽  
Vol 04 (04) ◽  
pp. 373-383 ◽  
Author(s):  
GWEN M. LECH
Keyword(s):  
Infrared Spectroscopy ◽  
Cognitive Function ◽  
Near Infrared Spectroscopy ◽  
Cognitive Aging ◽  
Near Infrared ◽  
Chronically Ill ◽  
Clinical Tool ◽  
Functional Near Infrared Spectroscopy ◽  
Cognitive Changes ◽  
Dementia Screening

This article presents a historical perspective of foundational studies utilizing near-infrared spectroscopy (NIRS) to measure the hemodynamics, oxygenation, and activation of the human brain cortex during cognitive tasks, called functional NIRS (fNIRS). It discusses studies representative of the diagnostic power and potential that fNIRS has shown for providing increased understanding of cognitive changes with aging and dementia. It concludes by discussing challenges that continue to confront the implementation of NIRS and fNIRS in clinical and translational research, in particular, the challenges to measure cognitive function and impairment in aged, chronically ill, and fragile subjects with or without dementia. It is written specifically in memoriam, honoring Britton Chance, therefore papers authored by him and his collaborative research family are weighted to illustrate the significant foundation and legacy he has left to this world.

DISCRIMINATIVE ANALYSIS OF FUNCTIONAL NEAR-INFRARED SPECTROSCOPY SIGNALS FOR DEVELOPMENT OF NEUROIMAGING BIOMARKERS OF ELDERLY DEPRESSION

2010 ◽  
Vol 03 (01) ◽  
pp. 69-74 ◽  
Author(s):  
YE ZHU ◽  
TIANZI JIANG ◽  
YUAN ZHOU ◽  
LISHA ZHAO
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Psychiatric Patients ◽  
Clinical Tool ◽  
Functional Near Infrared Spectroscopy ◽  
Classification Rate ◽  
Linear Discriminant ◽  
Discriminative Model ◽  
Neuroimaging Biomarkers

Functional near-infrared spectroscopy (fNIRS) is a neuroimaging technology which is suitable for psychiatric patients. Several fNIRS studies have found abnormal brain activations during cognitive tasks in elderly depression. In this paper, we proposed a discriminative model of multivariate pattern classification based on fNIRS signals to distinguish elderly depressed patients from healthy controls. This model used the brain activation patterns during a verbal fluency task as features of classification. Then Pseudo-Fisher Linear Discriminant Analysis was performed on the feature space to generate discriminative model. Using leave-one-out (LOO) cross-validation, our results showed a correct classification rate of 88%. The discriminative model showed its ability to identify people with elderly depression and suggested that fNIRS may be an efficient clinical tool for diagnosis of depression. This study may provide the first step for the development of neuroimaging biomarkers based on fNIRS in psychiatric disorders.

scholarly journals A Mini-Review on Functional Near-Infrared Spectroscopy (fNIRS): Where Do We Stand, and Where Should We Go?

Photonics ◽  
2019 ◽  
Vol 6 (3) ◽  
pp. 87 ◽  
Author(s):  
Quaresima ◽  
Ferrari
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Functional Neuroimaging ◽  
Wide Spectrum ◽  
Sport Performance ◽  
Cortical Activation ◽  
Clinical Tool ◽  
Functional Near Infrared Spectroscopy ◽  
Technical Developments

This mini-review is aimed at briefly summarizing the present status of functional near-infrared spectroscopy (fNIRS) and predicting where the technique should go in the next decade. This mini-review quotes 33 articles on the different fNIRS basics and technical developments and 44 reviews on the fNIRS applications published in the last eight years. The huge number of review articles about a wide spectrum of topics in the field of cognitive and social sciences, functional neuroimaging research, and medicine testifies to the maturity achieved by this non-invasive optical vascular-based functional neuroimaging technique. Today, fNIRS has started to be utilized on healthy subjects while moving freely in different naturalistic settings. Further instrumental developments are expected to be done in the near future to fully satisfy this latter important aspect. In addition, fNIRS procedures, including correction methods for the strong extracranial interferences, need to be standardized before using fNIRS as a clinical tool in individual patients. New research avenues such as interactive neurosciences, cortical activation modulated by different type of sport performance, and cortical activation during neurofeedback training are highlighted.

scholarly journals Effect of Light on Cognitive Function During a Stroop Task Using Functional Near-Infrared Spectroscopy

Phenomics ◽  
2021 ◽  
Author(s):  
Yafei Yuan ◽  
Guanghao Li ◽  
Haoran Ren ◽  
Wei Chen
Keyword(s):  
Infrared Spectroscopy ◽  
Cognitive Function ◽  
Near Infrared Spectroscopy ◽  
Stroop Task ◽  
Near Infrared ◽  
Brain Regions ◽  
Color Temperature ◽  
Light Conditions ◽  
Functional Near Infrared Spectroscopy ◽  
Effect Of Light

AbstractLight modulates human brain function through its effect on circadian rhythms, which are related to several human behavioral and physiological processes. Functional near-infrared spectroscopy (fNIRS) is a noninvasive optical neuroimaging technique used for recording brain activation during task performance. This study aimed to investigate the effects of light on cognitive function, particularly in the prefrontal cortex using fNIRS. The effect of light on cognitive modulation was analyzed using the Stroop task, which was performed on 30 participants under three different light conditions (color temperature 4500 K, 2500 K, and none). The behavioral results indicated that light conditions can easily and effectively modulate the performance of tasks based on the feedback, including the response time and accuracy. fNIRS showed hemodynamic changes in the bilateral dorsolateral prefrontal cortices, and the activated brain regions varied under different light conditions. Moreover, light may be regarded as a safe, effective, inexpensive, and accessible tool for modulating human cognitive function.

scholarly journals Functional near infrared spectroscopy (fNIRS) to assess cognitive function in infants in rural Africa.

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Sarah Lloyd-Fox ◽  
M. Papademetriou ◽  
M. K. Darboe ◽  
N. L. Everdell ◽  
R. Wegmuller ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Cognitive Function ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Functional Near Infrared Spectroscopy ◽  
Rural Africa

A Study of Frontal Signals in Brain Computer Interfaces: Interpretation of EEG & FNIRS

2020 ◽  
pp. 136-142
Author(s):  
S. Srilekha ◽  
B. Vanathi
Keyword(s):  
Infrared Spectroscopy ◽  
Healthy Subject ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Economic Conditions ◽  
Brain Computer Interfaces ◽  
Functional Near Infrared Spectroscopy ◽  
Computer Interfaces ◽  
Rehabilitation Devices

This paper focuses on electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) comparison to help the rehabilitation patients. Both methods have unique techniques and placement of electrodes. Usage of signals are different in application based on the economic conditions. This study helps in choosing the signal for the betterment of analysis. Ten healthy subject datasets of EEG & FNIRS are taken and applied to plot topography separately. Accuracy, Sensitivity, peaks, integral areas, etc are compared and plotted. The main advantages of this study are to prompt their necessities in the analysis of rehabilitation devices to manage their life as a typical individual.

61-LB: Use of Functional Near-Infrared Spectroscopy (fNIRS) to Assess Cognitive Effort in KATP-Related Neonatal Diabetes (KATP-NDM)

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 61-LB
Author(s):  
LISA R. LETOURNEAU-FREIBERG ◽  
KIMBERLY L. MEIDENBAUER ◽  
ANNA M. DENSON ◽  
PERSEPHONE TIAN ◽  
KYOUNG WHAN CHOE ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Neonatal Diabetes ◽  
Cognitive Effort ◽  
Functional Near Infrared Spectroscopy

The Use of fNIRS for Unique Contributions to Social and Affective Neuroscience

2019 ◽  
Author(s):  
Shannon Burns ◽  
Matthew D. Lieberman
Keyword(s):  
Infrared Spectroscopy ◽  
Social Interaction ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Affective Neuroscience ◽  
Functional Near Infrared Spectroscopy ◽  
Psychological Experience ◽  
The World ◽  
And Behavior ◽  
Meaningful Interaction

Social and affective neuroscience studies the neurophysiological underpinnings of psychological experience and behavior as it relates to the world around us. Yet, most neuroimaging methods require the removal of participants from their rich environment and the restriction of meaningful interaction with stimuli. In this Tools of the Trade article, we explain functional near infrared spectroscopy (fNIRS) as a neuroimaging method that can address these concerns. First, we provide an overview of how fNIRS works and how it compares to other neuroimaging methods common in social and affective neuroscience. Next, we describe fNIRS research that highlights its usefulness to the field – when rich stimuli engagement or environment embedding is needed, studies of social interaction, and examples of how it can help the field become more diverse and generalizable across participant populations. Lastly, this article describes how to use fNIRS for neuroimaging research with points of advice that are particularly relevant to social and affective neuroscience studies.

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