THE RELATION OF THE BLOOD SPECIFIC GRAVITY TO THE CELL COUNT, HEMOGLOBIN LEVEL, CELL VOLUME AND TOTAL BLOOD VOLUME IN PIGEONS

1928 ◽  
Vol 87 (1) ◽  
pp. 51-57 ◽  
Author(s):  
O. W. Barlow ◽  
R. W. Whitehead
Blood ◽  
1977 ◽  
Vol 49 (2) ◽  
pp. 301-307 ◽  
Author(s):  
R Alexanian

Abstract The plasma volume, red cell volume, or both were measured in 170 normal, anemic, or polycythemic subjects. For anemic subjects without a serum protein abnormality or splenomegaly, the relationship between hematocrit and red cell volume was linear and predictable. In patients with a serum monoclonal globulin on electrophoresis, the plasma voluem was significantly increased for the hematocrit in 30%, and the total blood volume was increased in 45%. The frequency of an elevated plasma volume was higher in patients with a markedly increased level of monoclonal protein. Reductions of abnormal proteins with chemotherapy were associated with declines in plasma volume. For a specific concentration, the serum viscosity was highest in patients with IgM proteins and lowest in patients with IgG globulins. Marked elevations in viscosity were noted only in sera with macroglobulinemia or with more than 5 g/dl of IgG or IgA globulins.


PLoS ONE ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. e0234835
Author(s):  
Wei Xia ◽  
Zong-jian Huang ◽  
Zhao-liang Guo ◽  
Yi-wei Feng ◽  
Chao-yin Zhang ◽  
...  

1963 ◽  
Vol 42 (4) ◽  
pp. 552-563 ◽  
Author(s):  
Thomas Falkheden ◽  
Björn Sjögren ◽  
Håkan Westling

ABSTRACT Using 51Cr-labelled red cells, studies on the blood volume were performed before and after hypophysectomy in five patients (three cases of metastatic mammary carcinoma and two cases of acromegaly). In addition, studies were performed only after hypophysectomy in nine patients (two cases of metastatic mammary carcinoma and seven diabetic subjects). All patients were on replacement therapy with cortisone (17,21-dihydroxy-pregn-4-ene-3,11,20-trione) postoperatively, and several cases also received thyroid and sex hormones. Hypophysectomy was followed by a decrease in the red cell volume, the calculated total blood volume, and the total amount of haemoglobin in the patients studied before and after operation. The differences in calculated total blood volume and the total amount of haemoglobin between all hypophysectomized patients and a series of control subjects were analyzed on the basis of body weight. The total blood volume and total haemoglobin were significantly reduced in the hypophysectomized group.


1958 ◽  
Vol 196 (1) ◽  
pp. 184-187 ◽  
Author(s):  
Magnus I. Gregersen ◽  
H. Sear ◽  
R. A. Rawson ◽  
Shu Chien ◽  
G. L. Saiger

Forty-two simultaneous measurements of plasma and cell volume with T-1824 and P32 were made on 18 normal monkeys ranging in weight from 3.4 to 7.1 kg. Nine determinations were made on two animals at varying intervals during a 16-month period. The mean values and standard deviations were as follows: cell volume 17.7 (S.D., 1.66) ml/kg; plasma volume, 36.4 (S.D., 3.98) ml/kg; blood volume, 54.0 (S.D., 4.72) ml/kg; Fcells factor, 0.83, (S.D., 0.046); venous cell percentage (hematocrit value x.96), 39.6; plasma protein (refractometer) 7.26 gm %. Variations among animals in plasma and blood volume, expressed in milliliters per kilogram were significantly greater than those observed in the same animal during the 16-month period.


1958 ◽  
Vol 196 (1) ◽  
pp. 188-192 ◽  
Author(s):  
Louise Wang

A method is described for the catheterization of the carotid of the rat which permits blood volume determinations to be made on unanesthetized animals. The cell volume (P32) and plasma volume (T-1824) were measured simultaneously on the day after catheterization. The average Fcells factor was 0.739 (S.D., 0.053) in 11 normal rats and 0.726 (S.D., 0.041) in 10 splenectomized rats. In 50 unanesthetized normal rats the plasma volume averaged 3.90 ml/100 gm body weight. The blood and cell volumes calculated by using the Fcells factor of 0.74 and the separately determined plasma trapping' factor of 0.95 averaged 5.93 ml/ 100 gm and 2.14 ml/100 gm, respectively. These values agree closely with those determined from the simultaneous measurement of cell and plasma volumes and also with the values obtained on 27 normal rats under ether.


1959 ◽  
Vol 196 (4) ◽  
pp. 703-705 ◽  
Author(s):  
E. J. Fedor ◽  
B. Fisher

Dogs lightly anesthetized with ether, maintained between 23–24°C for 2 hours and rewarmed, were subjected to simultaneous determinations of red cell volume (Cr51) and plasma volume (T-1824). Red cell volume values were unchanged during the course of the experiment. Plasma volumes were significantly decreased during hypothermia and were transiently elevated during rewarming. Twenty-four hours after rewarming, total blood volume and plasma volume values were not significantly different from control values. It would seem that circulatory failure (‘rewarming shock’) is not a usual feature of rewarming following hypothermia of 2 hours duration.


Blood ◽  
1977 ◽  
Vol 49 (2) ◽  
pp. 301-307 ◽  
Author(s):  
R Alexanian

The plasma volume, red cell volume, or both were measured in 170 normal, anemic, or polycythemic subjects. For anemic subjects without a serum protein abnormality or splenomegaly, the relationship between hematocrit and red cell volume was linear and predictable. In patients with a serum monoclonal globulin on electrophoresis, the plasma voluem was significantly increased for the hematocrit in 30%, and the total blood volume was increased in 45%. The frequency of an elevated plasma volume was higher in patients with a markedly increased level of monoclonal protein. Reductions of abnormal proteins with chemotherapy were associated with declines in plasma volume. For a specific concentration, the serum viscosity was highest in patients with IgM proteins and lowest in patients with IgG globulins. Marked elevations in viscosity were noted only in sera with macroglobulinemia or with more than 5 g/dl of IgG or IgA globulins.


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