scholarly journals Myoepithelial Cell-Rich Pleormorphic Adenoma of Minor Salivary Gland of Parapharyngeal Space

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Digvijay Singh Rawat ◽  
Divij Sonkhya ◽  
Nishi Sonkhya ◽  
Shubha Gupta

Parapharyngeal space tumors are rare and constitute only 0.5–1.0% of head and neck tumors. Minor salivary gland tumor is still rare in parapharyngeal space. We are reporting a case of pleomorphic adenoma of minor salivary gland of parapharyngeal space. A 42-year-old female presented with a history of mass in the oropharynx for 3 years. She presented with “hot potato voice” and dysphagia. CECT and MRI were done, showing large parapharyngeal space tumor. FNAC was suspicious for tumor of nerve cell origin. Tumor was excised using “paramedian mandibulotomy with mandibular swing approach”. Histopathological examination was inconclusive, suggesting possibility of extraskeletal myxoid chondrosarcoma, solitary fibrous tumor, neurogenic tumor. On immunohistochemistry, tumor was positive for cytokeratin, EMA (dim), S-100, and P 63 and negative for SMA thus proving the case as myoepithelial cell-rich pleomorphic adenoma.

2013 ◽  
Vol 28 (1) ◽  
pp. 24-27
Author(s):  
Sudipta Pal ◽  
Sampurna Pati ◽  
Somnath Saha ◽  
Vedula Padmini Saha

Objective: To present a case of carcinoma ex pleomorphic adenoma in the parapharyngeal space and discuss its management.   Methods: Design:            Case Report Setting:           Tertiary Government Teaching Hospital Subjects:         One   Results:  A 40-year-old male patient with dysphagia for three months and a left-sided mucosa-covered oropharyngeal mass was found to have a prestyloid parapharyngeal lesion on CT Scans. Fine Needle Aspiration Cytology (FNAC) revealed a pleomorphic adenoma. With a past history of parapharyngeal pleomorphic adenoma excised transorally three years before, the present mass was excised by mandibular swing approach. Post-operative recovery was uneventful, but the final histopathological report was carcinoma ex pleomorphic adenoma.   Conclusion: Malignant transformation should be suspected in recurrent salivary tumors in the parapharyngeal space. Provided there was truly no pre-existing malignant focus in the originally-excised tumor, and that early recurrence was not due to inadequate initial excision, this patient had a rare condition where the same tumor underwent malignant transformation within 3 years only. To the best of our knowledge, such an early transformation to malignancy of a minor salivary gland tumor of the parapharyngeal space has not been reported in the English literature.   Keywords: carcinoma ex pleomorphic adenoma, pleomorphic adenoma, carcinoma,  parapharyngeal space, malignant, transformation, minor salivary gland tumor,  mandibular swing


Author(s):  
Pankaj Chauhan ◽  
Rita Khanoria ◽  
Disha Sharma ◽  
Trilok C. Guleria

<p class="abstract">The parapharyngeal space is an inverted triangular pyramid. Parapharyngeal space masses account for 0.5% of all head and neck tumours and the majority is benign. Minor salivary gland tumour is a rare entity. A 75 years old female presented with a mass left side soft palate, per operatively mass of size about 6×3 cm was deeply extending to left parapharyngeal space and excised through transoral approach which came out to be pleomorphic adenoma of minor salivary gland on histopathological examination. Although external approach should be preferred due to important structure in vicinity but transoral approach can be used in selective cases.</p>


2016 ◽  
Vol 8 (3) ◽  
pp. 125-127
Author(s):  
Ankita Joshi ◽  
Chinmaya Sundar Ray

ABSTRACT Parapharyngeal space (PPS) lesions account for only 0.5% head and neck tumors and the majority of the minor salivary gland tumors are malignant. We report a case of pleomorphic adenoma of minor salivary gland in PPS as this is of a very rare occurrence. High index of suspicion and an adequate clearance of the tumor with a cuff of surrounding dispensable normal tissues are the key to successful treatment of such tumors. How to cite this article Ray CS, Joshi A. Primary Pleomorphic Adenoma of Minor Salivary Gland in the Parapharyngeal Space. Int J Otorhinolaryngol Clin 2016;8(3):125-127.


2021 ◽  
Vol 8 (1) ◽  
pp. 21-XX
Author(s):  
Shalina Kaur ◽  
Noor Dina Hashim ◽  
Afiza Izura M Mohammad Sofi ◽  
Gurdev Singh Naraman Singh ◽  
Khairil Amir Sayuti

Pleomorphic adenoma provides as much as 40-70% of tumors in the minor salivary gland with the palate being the most frequent area engaged. Head and neck tumors in parapharyngeal space amount to less than 1%. We share a case of pleomorphic adenoma primarily arising in parapharyngeal space. This report highlights clinical features, pathology, radiological findings, and treatment of this tumor.


2017 ◽  
Vol 6 (1) ◽  
pp. 159-162
Author(s):  
Punam Prasad Bhadani ◽  
◽  
Iffat Jamal ◽  
Suryakant Nirala ◽  
◽  
...  

2014 ◽  
Vol 62 (3) ◽  
pp. 319-324
Author(s):  
Christiano Sampaio QUEIROZ ◽  
Roberto Almeida de AZEVEDO ◽  
Antonio Irineu TRINDADE NETO ◽  
Caetano Guilherme Carvalho PONTES ◽  
Rafael de Queiroz MOURA

Pleomorphic adenoma is the most common neoplasm in major and minor salivary glands. It constitutes approximately 90% of all benign salivary gland lesions and the parotid is the most affected location. When the minor salivary glands are affected, it mostly occurs at the junction of the hard and soft palates. The diagnosis is complex because of the great histological variety and biological behavior of this tumor, a histopathological examination being essential. The recommended treatment is surgical excision. For lesions located superficially in the parotid gland, superficial parotidectomy - identifying and preserving the facial nerve - is necessary. Lesions in the palate or gums sometimes demand a margin of safety, being excised below the periosteum, including the overlying mucosa. With correct surgical removal, the prognosis is excellent. The aim of this study is to report a case of an unusual minor salivary gland pleomorphic adenoma in the hard palate, describing the most important aspects of this pathology.


2015 ◽  
Vol 03 (01) ◽  
pp. 047-050
Author(s):  
Gourav Ahuja ◽  
Jaideep Marya ◽  
Poonam Sood

AbstractSalivary gland tumors account for less than 3% of the head and neck tumors. Among various salivary gland tumors, pleomorphic adenoma is most common and accounts for 60- 70% of the benign tumors of salivary glands. However, the involvement of minor salivary glands of buccal mucosa is extremely uncommon and reported to be 4% only. Salivary glands may present with a diverse range of lesions presenting a challenge to even the most experienced clinician. We report two rare cases of pleomorphic adenoma of minor salivary glands of buccal mucosa in a 45 year old female and 70 years old male respectively. It includes clinical features, diagnosis and treatment of the tumor.


2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Serdal Celik ◽  
Osman Kilic ◽  
Tulay Zenginkinet ◽  
M. Tayyar Kalcioglu

Salivary gland tumors are rare among all head and neck tumors. Pleomorphic adenoma (PA) is the most commonly seen subtype, and 85% of the cases are located in the parotid gland. PA may very rarely be seen in minor salivary glands. Minor salivary gland PAs are mostly located in the hard and soft palates. Nasopharyngeal PA is very rare, and a total of 8 cases have been published to date. In this case report, a 51-year-old female patient who had nasopharyngeal PA with chondroid metaplasia is presented, and we review the relevant literature.


2018 ◽  
Vol VOLUME 6 (VOLUME 6 NUMBER 2 DECEMBER 2018) ◽  
pp. 38-41
Author(s):  
Amrita Srivastava

We are presenting a rare case of Pleomorphic adenoma cheek. A 60 year old female patient presented with a painless swelling in right cheek since 4 years. On examination a well circumscribed, soft to firm 1.5x1cm mass was palpable. FNAC revealed Pleomorphic adenoma. The diagnosis was confirmed by histopathological examination after excisional biopsy of tumor. Key words: pleomorphic adenoma, cheek, minor salivary gland


2015 ◽  
Vol 16 (7) ◽  
pp. 603-606
Author(s):  
Felipe Perozzo Daltoe ◽  
Liliane Janete Grando ◽  
Maria Inês Meurer ◽  
Elena Riet Correa Rivero ◽  
Filipe Modolo

ABSTRACT Mucoepidermoid carcinoma ex pleomorphic adenoma (MCxPA) is a rare salivary gland tumor predominantly found in major salivary glands. A case of MCxPA involving the soft tissue and bone of the retromolar region of a 26-year-old man is presented. The histopathological features revealed a neoplasm with predominance of pleomorphic adenoma (PA) elements, and presence of mucoepidermoid carcinoma malignant epithelial cells in several areas. Histochemical and immunohistochemical studies were positive for periodic acid Schiff, alcian blue, cytokeratins 7, 13, 14, and 19, Bcl-2, c-erbB-2, FGF-2 and maspin in the malignant areas. The patient underwent a partial resection of the left side of the mandible with neck dissection and MCxPA diagnosis was confirmed. How to cite this article Daltoe FP, Grando LJ, Meurer MI, Rivero ERC, Modolo F. A Rare Case of Mucoepidermoid Carcinoma ex Pleomorphic Adenoma arising in Minor Salivary Gland: Histopathological and Immunohistochemical Analysis. J Contemp Dent Pract 2015;16(7):603-606.


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