scholarly journals The Changing Phenotype of Inflammatory Bowel Disease

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Carthage Moran ◽  
Donal Sheehan ◽  
Fergus Shanahan
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Surgical Treatment ◽  
Cancer Risk ◽  
Bowel Disease ◽  
Mortality Rates ◽  
Phenotypic Changes ◽  
Disease Mortality ◽  
Elderly Onset ◽  
Inflammatory Bowel

It is widely known that there have been improvements in patient care and an increased incidence of Inflammatory Bowel Disease (IBD) worldwide in recent decades. However, less well known are the phenotypic changes that have occurred; these are discussed in this review. Namely, we discuss the emergence of obesity in patients with IBD, elderly onset disease, mortality rates, colorectal cancer risk, the burden of medications and comorbidities, and the improvement in surgical treatment with a decrease in surgical rates in recent decades.

N04 Knowledge, attitude and perception of inflammatory bowel disease patients towards colorectal cancer risk, its management and the role of healthcare providers: a cross-sectional study in the UK

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S659-S659
Author(s):  
F Khan ◽  
W Czuber-Dochan ◽  
C Norton
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Risk Management ◽  
Cancer Risk ◽  
Bowel Disease ◽  
Initiation Time ◽  
Cross Sectional ◽  
Early Cancer Diagnosis ◽  
Inflammatory Bowel

Abstract Background Inflammatory bowel disease (IBD) increases the risk of colorectal cancer (CRC) and requires specialised cancer risk management. Although literature exists on general disease-related knowledge in IBD patients, limited studies have assessed IBD patients’ knowledge of CRC risk and its management. Consequently, patient perception of the role of a healthcare provider (HCP) in patient education of CRC risk and their attitude towards recommended risk management has not been assessed in UK IBD patients. Methods We conducted a cross-sectional online survey with IBD patients recruited via charity sources from April-July 2019. Adult patients (>18 years) with a confirmed diagnosis of IBD for 2 years and adequate command of English language were included. A self-designed and piloted questionnaire with open and closed-ended questions was used. Closed-ended data were analysed using descriptive statistics and open-ended responses were analysed using content analysis. Fischer’s exact test and bivariate logistic regression were used to test for association between knowledge and patient demographics. Results 92 participants, including 52.5% CD and 67.5% females, responded. 88% knew that IBD increases CRC risk. The mean fear of CRC risk (0–10 visual analogue scale) was 6.37 (SD ± 2.8). One-fifth were aware of colonoscopy as the best screening tool; 88% were unaware of screening initiation time. 90% would agree to their doctor’s recommendation of colonoscopy to ensure early cancer diagnosis and treatment. For dysplasia with 10% risk of CRC, 46.7% would not agree to colectomy mainly due to 10% risk of CRC not being high enough to undergo surgery. Forty-eight per cent of participants said that they never had a discussion about increased CRC risk in IBD with their doctor. Almost two-thirds were not informed about the role of screening/surveillance in cancer. Two-thirds were satisfied with the information provided by their HCP. Overall, patients desired more information about their individualised cancer risk and services available for managing the increased risk. Conclusion IBD patients are well informed about IBD-associated CRC risk, feared this risk greatly but were poorly aware of screening initiation time. HCP’s role in cancer knowledge dissemination was sub-optimal and patients desired more knowledge. We need deeper understanding of patients’ educational needs related to CRC.

Abstract 3645:CD24polymorphisms and susceptibility to inflammatory bowel disease and colorectal cancer risk

2014 ◽  
Author(s):  
Victoria Lisiansky ◽  
Sarah R. Kraus ◽  
Inna Naumov ◽  
Dina Kazanov ◽  
Ilana Nabiochtchikov ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Cancer Risk ◽  
Bowel Disease ◽  
Colorectal Cancer Risk ◽  
Inflammatory Bowel

scholarly journals Variation at 2q35 (PNKDandTMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

2016 ◽  
Vol 25 (11) ◽  
pp. 2349-2359 ◽  
Author(s):  
Giulia Orlando ◽  
Philip J. Law ◽  
Kimmo Palin ◽  
Sari Tuupanen ◽  
Alexandra Gylfe ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Cancer Risk ◽  
Bowel Disease ◽  
Pleiotropic Effect ◽  
Colorectal Cancer Risk ◽  
Inflammatory Bowel

Patients’ knowledge and fear of colorectal cancer risk in inflammatory bowel disease

2016 ◽  
Vol 17 (6) ◽  
pp. 383-391 ◽  
Author(s):  
Anthony Lopez ◽  
Benjamin Collet-Fenetrier ◽  
Arthur Belle ◽  
Laurent Peyrin-Biroulet
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Cancer Risk ◽  
Bowel Disease ◽  
Colorectal Cancer Risk ◽  
Inflammatory Bowel

scholarly journals Colorectal cancer risk in patients with inflammatory bowel disease and Lynch syndrome

2010 ◽  
Vol 8 (Suppl 1) ◽  
pp. P1 ◽  
Author(s):  
Melyssa Aronson ◽  
Joanne Stempak ◽  
Mark Silverberg ◽  
Kara Semotiuk ◽  
Robert Gryfe ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Cancer Risk ◽  
Lynch Syndrome ◽  
Bowel Disease ◽  
Colorectal Cancer Risk ◽  
Inflammatory Bowel

Colorectal Cancer Risk in Patients With Lynch Syndrome and Inflammatory Bowel Disease

2017 ◽  
Vol 15 (3) ◽  
pp. 454-458.e1 ◽  
Author(s):  
Lauranne A.A.P. Derikx ◽  
Lisa J.T. Smits ◽  
Shannon van Vliet ◽  
Evelien Dekker ◽  
Cora M. Aalfs ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Cancer Risk ◽  
Lynch Syndrome ◽  
Bowel Disease ◽  
Colorectal Cancer Risk ◽  
Inflammatory Bowel
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