scholarly journals High Seroprevalence of SARS-CoV-2 (COVID-19)-Specific Antibodies among Healthcare Workers: A Cross-Sectional Study in Guilan, Iran

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Heydar Ali Balou ◽  
Tofigh Yaghubi Kalurazi ◽  
Farahnaz Joukar ◽  
Soheil Hassanipour ◽  
Mohammad Shenagari ◽  
...  
Keyword(s):  
Odds Ratio ◽  
Healthcare Workers ◽  
Antibody Test ◽  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Age Group ◽  
Igg Antibodies ◽  
Sectional Study ◽  
Cross Sectional ◽  
Wide Range

Background. This study was conducted to evaluate the anti‐SARS‐CoV‐2 IgM and IgG antibodies among healthcare workers in Guilan. Methods. This cross-sectional study was conducted on 503 healthcare workers. Between April and May 2020, blood samples were collected from the healthcare workers of Razi Hospital in Rasht, Guilan, Iran. Enzyme-linked immunosorbent assay (ELISA) was used for the detection and quantitation of anti‐SARS‐CoV‐2 IgM/IgG antibodies by using kits made by Pishtaz Teb Company, Tehran, Iran. Results. From a total of 503 participants, the result of the anti‐SARS‐CoV‐2 IgM antibody test was positive in 28 subjects (5.6%) and the anti‐SARS‐CoV‐2 IgG antibody test was positive in171 subjects (34%). Participants in the age group of 35–54 years were significantly more likely to have a positive anti‐SARS‐CoV‐2 antibody test than the age group of 20–34 years (odds ratio = 1.53, 95% CI: 1.04–2.25, P = 0.029 ). Also, physicians were significantly more likely to have a positive antibody test than office workers (odds ratio = 1.92, 95% CI: 1.04–3.54, P = 0.037 ). The wide range of symptoms was significantly associated with the positive anti‐SARS‐CoV‐2 antibody test. The most significant association was observed between fever and a positive anti‐SARS‐CoV‐2 antibody test (odds ratio = 3.03, 95% CI: 2.06–4.44, P < 0.001 ). Conclusion. The results of the current study indicated that the seroprevalence of COVID-19 was high among healthcare workers of Guilan Province. It seems that this finding was due to the earlier exposure to COVID-19 and the lack of awareness and preparedness to deal with the pandemic in Iran, compared to other countries.

scholarly journals A cross-sectional study on morbidity status among school going adolescents in Thiruvallur district, Tamil Nadu

2019 ◽  
Vol 6 (12) ◽  
pp. 5201
Author(s):  
Sathish Dev D. ◽  
Sugantha Valli M. ◽  
Gnana Sezhian M. ◽  
Suganya E.
Keyword(s):  
Tamil Nadu ◽  
Gastrointestinal Disease ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Health Problems ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Wide Range ◽  
Tract Infections

Background: Adolescents represent about 21.8 percent of India’s population. Various health risks with potentially life-threatening consequences become prominent in this age group. This study was undertaken with the objective to determine the morbidity profile of school going adolescents in Tamil Nadu.Methods: This descriptive, cross sectional study was planned and conducted from January 2016 to August 2017. The study population included 987 adolescent boys and girls aged between 10 to 19 years studying in high and higher secondary Government schools of Thiruvallur district of Tamil Nadu. Semi-structured questionnaire was used as data collection tool.Results: The mean age groups of this school going adolescent are 14.2 yrs. In the present study 583 (59%) of the study participants were affected by one or more morbidity condition. Among them, 395 (67.7%) were in the age group 10-14 years and 188 (32.2%) in the age group 15-19 years. 122 (21%) and 461 (79.1%) of male and female were affected respectively. In the present study, fever (21%) was the commonest reported morbidity followed by acute respiratory infection (15.7%) and acute gastrointestinal disease (13. 4%).Conclusions: This study shows that adolescents are prone to a wide range of morbidity conditions. Apart from respiratory and gastro intestinal diseases, reproductive tract infections and sexual health problems are important morbidities affecting this age group. There is strong need to sensitize health care practitioners at all levels, in both government and private sectors towards health problems in adolescent age groups.

scholarly journals Dengue in the campus community of an overseas American university: A cross-sectional study

2019 ◽  
Vol 13 (03) ◽  
pp. 233-239
Author(s):  
Hamish Mohammed ◽  
Mary H Hayden ◽  
Elise Lee ◽  
Luis M Santiago ◽  
Rosina C Krecek ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Denv Infection ◽  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Campus Community ◽  
Igg Antibodies ◽  
Sectional Study ◽  
Cross Sectional ◽  
American University

Introduction: After a large outbreak of dengue virus (DENV) serotype-3 in Saint Kitts and Nevis (SKN) in 2008, we performed a cross-sectional study to determine the prevalence of anti-DENV immunoglobulin G (IgG) antibodies in expatriate and local persons affiliated with an American veterinary school there. Methodology: This campus community comprised mostly expatriate students and faculty and Kittitian administrative staff. In 2009, a stratified random sample of students, faculty and staff was invited to complete an electronic survey to assess risk factors for DENV and provide blood for testing for anti-DENV IgG antibodies by an enzyme-linked immunosorbent assay. IgG-positive specimens were also tested by a 90% plaque reduction neutralization test (PRNT90) to determine immunoreactivity to DENV (1-4) serotypes and West Nile virus. Risk factors for anti-DENV IgG seropositivity were determined using simple and adjusted logistic regression. Results: Of the 118 participants, the overall prevalence of DENV IgG antibodies was 44.1% (95% confidence interval [CI]: 35.1-53.0%), ranging from 30.1% in students, 100.0% in staff and 57.9% in faculty (p < 0.001). Duration of residence in St. Kitts was the only variable significantly associated with seropositivity on multiple logistic regression (adjusted odds ratio [95% CI]: 1.21 [1.07-1.37]). The serotype of DENV was determined in 11 persons: DENV-1 (n = 4), DENV-2 (n = 3), and DENV-3 (n = 4). Conclusions: Expatriate students and faculty moving to St. Kitts from non-endemic areas were at high risk of DENV infection. There is a need for increased emphasis on pre-travel mosquito-borne virus prevention education for persons moving to St. Kitts to study and work.

Stigmatization of Healthcare Workers during the COVID-19 Pandemic

2021 ◽  
Vol 15 (6) ◽  
pp. 1379-1383
Author(s):  
M. F. Khalid ◽  
M. Alam ◽  
F. Rehman ◽  
R. Sarfaraz
Keyword(s):  
Data Collection ◽  
Healthcare Workers ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Collection Data ◽  
Doctors And Nurses

Aim: To study stigmatization of healthcare workers due to COVID-19 pandemic Methodology: Using a cross-sectional study, a total of 134 healthcare workers were approached at Mayo Hospital, Lahore. An interview based, pre-tested, semi-constructed questionnaire consisting of both open and close ended questions were used for data collection. Data was analyzed using SPSS version 26. Results: Out of 134 healthcare workers, 40.3% were male and 59.7% were female. Distribution among doctors and nurses was 60.4% and 39.6% respectively. 51.5% of healthcare workers felt stigmatized due to working in the COVID-19 pandemic. 69.4% of healthcare workers knew of other people who faced similar stigmatization due to their exposure to COVID-19. Almost each age group and specialty faced such stigmatization. Conclusion: This study helped in understanding the stigma healthcare workers had to face during COVID-19 Pandemic which lead to significant distress and suffering for the healthcare workers. Keywords: COVID-19, pandemic, stigmatization, healthcare workers

scholarly journals Prevalence of hypertension and its associated risk factors in young adults attending a tertiary care institute of Nagpur: a cross sectional study

2017 ◽  
Vol 4 (10) ◽  
pp. 3630
Author(s):  
Chaitanya R. Patil ◽  
Durgesh Prasad Sahoo ◽  
Manjusha Dhoble ◽  
Abhijit Kherde ◽  
Asim Inamdar
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Young Adults ◽  
Odds Ratio ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Associated Risk Factors

Background: Hypertension is a silent killer and global public health problem. With the advent of globalization affecting the lifestyle of the population, non-communicable diseases like hypertension, diabetes etc. is affecting the young adults (18 to 40 years). The aim of the study was to estimate the prevalence of hypertension and its associated risk factors among young adults (18 to 40 years) attending a tertiary care centre of Nagpur.Methods: This was a cross sectional study on 370 participants of age 18 to 40 years attending the outpatient department of urban health training centre in Nagpur. Data was collected using pretested and pre designed questionnaire and anthropometric measurements were done by standard guidelines. Blood pressure was measured using sphygmomanometer in sitting position. Data was analyzed using Epi info version 7.2. Chi square test/ fisher’s exact test has been used to find the difference between two proportions. Unadjusted odds ratio was calculated for various risk factors studied. Stepwise logistic regression analysis was done to calculate the adjusted odds ratio. Results: The prevalence of hypertension was found to be 23.24%. The prevalence was higher among males (25%) when compared to females (22.3%). Body mass index and waist hip ratio were significantly higher among the hypertensive when compared to normotensive study population (p<0.01). For every one year increase in age, the odds ratio increases by 1.06 (1.02 to 1.09) and the subjects who were overweight were having 2.15 odds of being hypertensive. Conclusions: We found a high prevalence of hypertension among the adults of age group of 18 to 40 years. The population with high body mass index, high waist to hip ratio and age group of 30 to 40 years were found to be associated with hypertension. Early surveillance and prompt treatment forms will help in decreasing the cardiovascular risk of young adults in near future. 

scholarly journals Seroprevalence of antibodies against varicella zoster virus and rubella virus among newly recruited expatriate healthcare workers: a cross-sectional study

BMJ Open ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. e019339
Author(s):  
Ibrahim Shady
Keyword(s):  
Varicella Zoster Virus ◽  
Rubella Virus ◽  
Healthcare Workers ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Varicella Zoster ◽  
Occupation Group

ObjectivesTo assess the state of immunity to varicella zoster virus (VZV) and rubella virus (RV) among newly recruited healthcare workers (HCWs) in Kuwait before they begin work, and to determine whether there are differences in the prevalence of seronegativity according to nationality, gender, age group and occupation group.SettingThis cross-sectional study involved analysis of blood samples from workers newly recruited to the Kuwaiti healthcare system.ParticipantsAll new non- national HCWs recruited during the study period (n=1540).InterventionEnzyme-linked immunoassays for VZV-specific and RV-specific IgG were performed.ResultsAmong HCWs, 81.9% and 93.5% were immune to VZV and RV, respectively. Male seronegativity was higher than that of females for both viruses. Regarding VZV, the majority of seronegative individuals were Indians (23.5%), followed by Somalis (12.5), Filipinos (6.5) and Egyptians (5.4%); the between-group differences were significant for all groups. The age groups 20–30 and 30–40 years were most likely to be seronegative, with prevalences of 18.2% and 18.9%, respectively. VZV seronegativity was most common among nurses (21.1%) and least common among physicians (9.2%), and the difference was significant. In addition, RV seronegativity was most frequent among Somalis (12.5%) and lowest among Indians (5.3%); other nationalities (Egyptian, Filipino and others) ranged between 9.1% and 9.6%. Seronegative individuals were most frequently in the younger age group (<20 years old) (17.5%), followed by the >40 years old group (10.4%). RV seronegativity was highest among nurses (6.9%) and lowest among physicians (5.2%).ConclusionThe prevalence of seronegativity is highest among Indians for VZV and Somalis for RV, and HCWs aged 20–40 years for VZV and <20 years for RV. For both viruses, the seronegativity rate was highest for male HCWs, and for nurses compared with other HCWs, with physicians having the lowest prevalence of both viruses.

scholarly journals Novel coronavirus seropositivity and related factors among healthcare workers at a university hospital: a cross-sectional study

2021 ◽  
Author(s):  
Aziz Ogutlu ◽  
Oguz Karabay ◽  
Unal Erkorkmaz ◽  
Ertugrul Guclu ◽  
Seher Sen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Healthcare Workers ◽  
Antibody Test ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Test Results ◽  
Sectional Study ◽  
Cross Sectional ◽  
Antibody Positivity ◽  
Novel Coronavirus

Abstract Background In this study, it is aimed to investigate the specific risk factors for the transmission of novel coronavirus (SARS-CoV-2) among healthcare workers in different campuses of a university hospital and to reveal the risk factors for antibody positivity. Methods In this cross-sectional study, 2988 (82%) of 3620 healthcare workers in a university hospital participated. The Coronavirus Disease (COVID-19) antibody was investigated by taking serum to the healthcare workers who accepted for the COVID-19 antibody test. The antibody test results of the participants were evaluated according to the campus they work, their profession and their workplace. Statistical significance level was accepted as p < 0.05 in all analyzes. Results Of the antibody test results of the participants in this study, 108 (3.6%) were positive and 2880 (96.4%) were negative. Antibody positivity were higher in nurses than in other healthcare workers (p < 0.001). When examined according to work places, antibody positivity was higher in those working in intensive care compared to those working in other places (p < 0.001). Conclusions Healthcare workers are at the highest risk of being infected with COVID-19. Those who have a higher risk of infection among healthcare workers and those working in high-risk areas should be vaccinated early and take care to work with personal protective equipment during the pandemic period. Trial Registration: Retrospective permission was obtained from both the local ethics committee and the Turkish Ministry of Health for this study. (IRB No:71522473/050.01.04/370, Date: 05.20.2020

scholarly journals Seroprevalence of COVID-19 IgG antibodies among healthcare workers of Pakistan: a cross-sectional study assessing exposure to COVID-19 and identification of high-risk subgroups

BMJ Open ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. e046276
Author(s):  
Hijab Batool ◽  
Omar Chughtai ◽  
Muhammad Dilawar Khan ◽  
Akhtar Sohail Chughtai ◽  
Shakeel Ashraf ◽  
...  
Keyword(s):  
Living Arrangements ◽  
Healthcare Workers ◽  
Absolute Risk ◽  
Cross Sectional Study ◽  
Work Place ◽  
Igg Antibodies ◽  
Sectional Study ◽  
Igg Antibody ◽  
Cross Sectional ◽  
Professional Category

ObjectiveIn this study, we aimed to find the seroprevalence of healthcare workers (HCWs) of Pakistan involved in the treatment and care of patients with COVID-19.SettingThis was a cross-sectional study and total of 15 000 HCWs involved in providing services and care to the patients with COVID-19 were randomly selected from all over Pakistan.ParticipantsInformed consent was taken from all participants and were included according to inclusion and exclusion criteria. All testing was done on serum samples for the qualitative detection of SARS-CoV-2 IgG antibodies using Abbott Chemiluminescent microparticle immunoassay. An index of 1.4 was used as a cut-off to mark reactive and non-reactive cases. SPSS V.23.0 was used for data analysis.OutcomeImmune status of the study population depicting seroprevalence among HCWs.ResultsOut of all the candidates, majority of the HCWs were men (61.9%) and were doctors (62.4%). The mean age of participants was 32.8 years (SD 8.7) and majority were asymptomatic (51.8%). In this study, 33% of the HCWs were reactive for SARS-CoV-2 IgG antibody. Around 44% of the reactive cases were asymptomatic. The symptoms more significantly associated with seropositivity were: fever (OR 1.31; 95% CI 1.16 to 1.48), headache (OR 2.43; 95% CI 2.16 to 2.73), cough and shortness of breath (OR 2.10; 95% CI 1.91 to 2.31), loss of sense of smell or taste (OR 3.70; 95% CI 3.29 to 4.17) (p<0.001). Factors which showed significant association with the presence of antibodies were professional category (absolute risk (AR) 0.09; OR 1.46; 95% CI 1.36 to 1.56), availability of protective masks (AR 0.02; OR 0.90; 95% CI 0.84 to 0.96), safety goggles (AR 0.02; OR 0.90; 95% CI 0.84 to 0.97) and living arrangements (AR 0.03; OR 1.12; 95% CI 1.04 to 1.20) (p<0.05).ConclusionOur study showed a high seropositivity of HCWs dealing with patients with COVID-19 in Pakistan revealing significant association with professional category, nature of work place and precautions taken while performing duties.

Suicidal Death Autopsy Analysis at Dhaka Medical College

1970 ◽  
Vol 40 (1) ◽  
pp. 18-21 ◽  
Author(s):  
MN Hossain ◽  
Z Rahman ◽  
S Akhter
Keyword(s):  
Forensic Medicine ◽  
Causes Of Death ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Autopsy Report ◽  
Common Causes ◽  
Suicidal Death

A cross sectional study was carried out at the department of Forensic Medicine in Dhaka Medical College during the period of January 2008 to December 2009. Data were collected from 3rd copy of the post mortem reports which were preserved in the department of Forensic Medicine with the verbal consent of the doctors who performed autopsy report. During this period total 5114 autopsies were conducted. Out of this 970 cases (19%) were suicidal in nature. It was noticed that all suicidal deaths occurred from 10 years to all age group respectively, but top amongst age group of suicidal deaths occurred in between 21 to 30 years of people. Suicidal deaths are more common in female than male. Suicidal deaths due to hanging is highest, next common causes of death due to organophosphorus compund poisoning. Suicidal deaths by hanging is more in female than male but in poisoning cases male are more lvictimised than female. Objectives of our study are to see the occurrence and methods of suicidal death. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9957 BMJ 2011; 40(1): 18-21

End Organ Damage in Hypertensive Geriatric Age Group: A Cross Sectional Study

2017 ◽  
Vol 1 (3) ◽  
pp. 10-16
Author(s):  
Prakashkumar Kyada ◽  
Kunal Jadhav ◽  
T. K. Biswas ◽  
Varshil Mehta ◽  
Sojib Bin Zaman
Keyword(s):  
Ventricular Hypertrophy ◽  
Organ Damage ◽  
Cross Sectional Study ◽  
Left Ventricular ◽  
Age Group ◽  
Sectional Study ◽  
Isolated Systolic Hypertension ◽  
Cross Sectional ◽  
End Organ Damage ◽  
Common Risk Factors

Objective: Hypertension is one of the common risk factors for cardiovascular and cerebrovascular diseases/disorders A developing country like India faces the double burden of communicable and non-communicable diseases; of the which, hypertension is the most important treatable cause of mortality and morbidity with loss of functional capacity and decline in the quality of life. Aim: To study the prevalence of end organ damage in the hypertensive geriatric age group. Method: The present study was a cross sectional study, conducted in 150 elderly patients admitted in MGM Hospital, Navi Mumbai, India with the diagnosis of stage I or II hypertension from 2011 to 2013. Results: Data analysis of the present study showed that 68% of elderly population aged between 60 to 69 years were suffering from hypertension. Compared to males, females had a higher rate of target organ damage. This study found that out of all patients with total end organ damage, 54.6 % had CVS complications, 15.7 % had hypertensive retinopathy, 25.9 % and 18.51 had raised creatinine and proteinuria respectively. 19.4 % had cerebrovascular accident (CVA) complications. Among Cardiovascular related complications Coronary artery disease (CAD) was found in 21 patients, out of them 7 had Congestive cardiac Failure (CCF). Left Ventricular Hypertrophy (LVH) was the most common complication and seen in 38 patients. 13.8 % patients had Regional Wall Motion Abnormality (RWMA) Conclusion: The present study concluded that Isolated Systolic Hypertension (ISH) is the commonest type of hypertension in geriatric age group. This study concluded that the most common risk factors of HTN in the elderly are sedentary life style, dyslipidemia and extra salt intake while the most common end organ damage was observed to be Left Ventricular Hypertrophy followed by renal dysfunction. Keywords:  Hypertension,  Isolated Systolic Hypertension, Dyslipidemia.

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