scholarly journals Overview of Microvascular Angina Pectoris and Discussion of Traditional Chinese Medicine Intervention

2022 ◽  
Vol 2022 ◽  
pp. 1-8
Author(s):  
Linghua Yu ◽  
Xiaoyan Lu ◽  
Chenxi Xu ◽  
Tong Li ◽  
Yanling Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Angina Pectoris ◽  
Traditional Chinese Medicine ◽  
Ischemia Reperfusion ◽  
Modern Medicine ◽  
Hypoxia Tolerance ◽  
Microvascular Angina ◽  
Myocardial Hypoxia ◽  
Artery Disease ◽  
New Research

Previous research and treatment of coronary heart disease mostly focused on the large epicardial vessels, with limited research on the small endocardial coronary arteries or arterioles that could not be detected by coronary angiography, especially microvascular angina caused by microvascular stenosis or microcirculation dysfunction. Conventional Western medicine therapies have no specific efficacy, but traditional Chinese medicine has significant advantages in this regard. In particular, traditional Chinese medicine of supplementing Qi and activating blood circulation protects the vascular endothelium, relaxes coronary microvessels, reduces myocardial no-reflow after ischemia-reperfusion, increases myocardial hypoxia tolerance, constrains the aggregation of platelet, and increases the rate of blood flow. Moreover, these treatments can significantly improve patients’ symptoms through multitarget comprehensive intervention. Here, we analyzed the pathogenesis of microvascular angina pectoris, the treatment status of modern medicine, and the research on the multitarget intervention of traditional Chinese medicine to provide new research ideas for correctly identifying the role of coronary microcirculation in coronary artery disease to solve clinical problems and prevent cardiovascular events.

scholarly journals Ischemia-Reperfusion Injury in Peripheral Artery Disease and Traditional Chinese Medicine Treatment

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Zenghui Liang ◽  
Wentao Zhang ◽  
Tianyi Zhu ◽  
Yunsong Li ◽  
Pengkai Cao ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Mitochondrial Dysfunction ◽  
Reperfusion Injury ◽  
Peripheral Artery Disease ◽  
Ischemia Reperfusion Injury ◽  
Cell Damage ◽  
Ischemia Reperfusion ◽  
Peripheral Artery ◽  
Artery Disease

Peripheral artery disease (PAD) is a serious public health issue, characterized by circulation disorder of the lower extreme that reduces the physical activity of the lower extremity muscle. The artery narrowed by atherosclerotic lesions initiates limb ischemia. In the progression of treatment, reperfusion injury is still inevitable. Ischemia-reperfusion injury induced by PAD is responsible for hypoxia and nutrient deficiency. PAD triggers hindlimb ischemia and reperfusion (I/R) cycles through various mechanisms, mainly including mitochondrial dysfunction and inflammation. Alternatively, mitochondrial dysfunction plays a central role. The I/R injury may cause cells’ injury and even death. However, the mechanism of I/R injury and the way of cell damage or death are still unclear. We review the pathophysiology of I/R injury, which is majorly about mitochondrial dysfunction. Then, we focus on the cell damage and death during I/R injury. Further comprehension of the progress of I/R will help identify biomarkers for diagnosis and therapeutic targets to PAD. In addition, traditional Chinese medicine has played an important role in the treatment of I/R injury, and we will make a brief introduction.

Opening up a New Field of Modern Medical Research 1

2020 ◽  
Author(s):  
Xiaoguang Li
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Human Body ◽  
Low Cost ◽  
Acupuncture Point ◽  
Modern Medicine ◽  
Body Structure ◽  
Special Effect ◽  
Special Knowledge ◽  
Opening Up

Modern medicine tells us that the human body is an organism composed of heart, lung, liver, kidney, spleen, stomach, brain, nerves, muscles, bones, blood vessels, blood and so on, while traditional Chinese medicine believes that besides these tissues and organs, the human body still has another part of the structure, traditional Chinese medicine calls them Jing Luo and Shu Xue. Jing Luo means the longitudinal line of the human body and the accompanying net, translated into English Meridians and Collaterals. Shu Xue means holes distributed on Jing Luo and outside Jing Luo, because stimulating Shu Xue's position by acupuncture, massage and other methods can cure diseases, so Shu Xue is translated into English acupuncture point, abbreviated as acupoint or point. Meridians and acupoints are the special knowledge of human body structure in traditional Chinese medicine. Traditional Chinese medicine not only draws the distribution map of the meridians and acupoints in the human body, but also has been using them to treat diseases for thousands of years. There are hundreds of these acupoints, stimulating each one by acupuncture, massage or other methods will have a special effect on the human body and can treat various diseases. But what effect does stimulating every acupoint have on the human body so that it can treat various diseases? The discussion of traditional Chinese medicine is vague and incomprehensible, and can not be proved by experiments. According to the author's research for more than 30 years, this paper makes a clear and accurate exposition of the effects on the human body and diseases that can be treated with acupoint massage. These statements can be proved by experiments, so they are believed to be reliable. It is hoped that meridians, acupoints and massage therapy can be incorporated into modern medicine and become a part of modern medicine after being proved by others through experiments. Massaging acupoints can not only treat many diseases that are difficult to be treated with drugs, but also have simple methods and low cost.

1+1 > 2: Integration of the Host-directed Traditional Chinese Medicine and the Virus-targeted Modern Medicine in Control of COVID-19

2020 ◽  
Vol 7 (2) ◽  
pp. 89-94
Author(s):  
Jianjun Sun
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Infectious Diseases ◽  
Modern Medicine ◽  
The World ◽  
Plausible Mechanism

The COVID-19 pandemic has caused millions of infections and hundreds of thousands deaths in the world. The pandemic is still ongoing and no specific antivirals have been found to control COVID-19. The integration of Traditional Chinese Medicine with supportive measures of Modern Medicine has reportedly played an important role in the control of COVID-19 in China. This review summarizes the evidence of TCM in the treatment of COVID-19 and discusses the plausible mechanism of TCM in control of COVID-19 and other viral infectious diseases.

Systems Biology Technologies Enable Personalized Traditional Chinese Medicine: A Systematic Review

2012 ◽  
Vol 40 (06) ◽  
pp. 1109-1122 ◽  
Author(s):  
Xijun Wang ◽  
Aihua Zhang ◽  
Hui Sun ◽  
Ping Wang
Keyword(s):  
Systems Biology ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Disease Diagnosis ◽  
Modern Medicine ◽  
Therapeutic Approaches ◽  
Current Trends ◽  
Close Relationship ◽  
The Right ◽  
Personalize Medicine

Traditional Chinese medicine (TCM), an alternative medicine, focuses on the treatment of human disease via the integrity of the close relationship between body and syndrome analysis. It remains a form of primary care in most Asian countries and its characteristics showcase the great advantages of personalized medicine. Although this approach to disease diagnosis, prognosis and treatment has served the medical establishment well for thousands of years, it has serious shortcomings in the era of modern medicine that stem from its reliance on reductionist principles of experimentation and analysis. In this way, systems biology offers the potential to personalize medicine, facilitating the provision of the right care to the right patient at the right time. We expect that systems biology will have a major impact on future personalized therapeutic approaches which herald the future of medicine. Here we summarize current trends and critically review the potential limitations and future prospects of such treatments. Some characteristic examples are presented to highlight the application of this groundbreaking platform to personalized TCM as well as some of the necessary milestones for moving systems biology of a state-of-the-art nature into mainstream health care.

scholarly journals Xiaojin Pill with natural musk in the treatment of plasma cell mastitis

2021 ◽  
Vol 6 (3) ◽  
Keyword(s):  
Surgical Treatment ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Plasma Cell ◽  
Plasma Cells ◽  
Modern Medicine ◽  
Breast Diseases ◽  
Benign Breast Diseases

Introduction: Plasma cell mastitis is a rare benign suppurative disease of the breast based on the dilatation of mammary ducts and infiltration of plasma cells. Modern medicine focuses on surgical treatment. It is easy to recur after operation. Xiaojin Pill with natural musk is a oral traditional Chinese medicine and plays a role in benign breast diseases. There are very few reports on the use of Xiaojin Pill with natural musk in treating plasma cell mastitis yet. Cases: This paper reports 3 cases of plasma cell mastitis who received Xiaojin Pill with natural musk treatment. Patients were successfully treated after accepting Xiaojin Pill with natural musk for several weeks.

scholarly journals The Role of Traditional Chinese Medicine in the Regulation of Oxidative Stress in Treating Coronary Heart Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Xinyu Yang ◽  
Tianmai He ◽  
Songjie Han ◽  
Xiaoyu Zhang ◽  
Yang Sun ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Antioxidant Treatment ◽  
Molecular Systems ◽  
Artery Disease ◽  
Signal Activation

Oxidative stress has been closely related with coronary artery disease. In coronary heart disease (CHD), an excess of reactive oxygen species (ROS) production generates endothelial cell and smooth muscle functional disorders, leading to a disequilibrium between the antioxidant capacity and prooxidants. ROS also leads to inflammatory signal activation and mitochondria-mediated apoptosis, which can promote and increase the occurrence and development of CHD. There are several kinds of antioxidative and small molecular systems of antioxidants, such as β-carotene, ascorbic acid, α-tocopherol, and reduced glutathione (GSH). Studies have shown that antioxidant treatment was effective and decreased the risk of CHD, but the effect of the treatment varies greatly. Traditional Chinese medicine (TCM) has been utilized for thousands of years in China and is becoming increasingly popular all over the world, especially for the treatments of cardiovascular diseases. This review will concentrate on the evidence of the action mechanism of TCM in preventing CHD by modulating oxidative stress-related signaling pathways.

scholarly journals Smart Responsive Nanoformulation for Targeted Delivery of Active Compounds From Traditional Chinese Medicine

2020 ◽  
Vol 8 ◽  
Author(s):  
Xuejun Jiang ◽  
Mei Lin ◽  
Jianwen Huang ◽  
Mulan Mo ◽  
Houhe Liu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Targeted Delivery ◽  
Drug Delivery Systems ◽  
Redox Status ◽  
Modern Medicine ◽  
Active Compounds ◽  
Stimulus Responsive ◽  
Internal Stimulus ◽  
Targeted Release

Traditional Chinese medicine (TCM) has been used to treat disorders in China for ~1,000 years. Growing evidence has shown that the active ingredients from TCM have antibacterial, antiproliferative, antioxidant, and apoptosis-inducing features. However, poor solubility and low bioavailability limit clinical application of active compounds from TCM. “Nanoformulations” (NFs) are novel and advanced drug-delivery systems. They show promise for improving the solubility and bioavailability of drugs. In particular, “smart responsive NFs” can respond to the special external and internal stimuli in targeted sites to release loaded drugs, which enables them to control the release of drug within target tissues. Recent studies have demonstrated that smart responsive NFs can achieve targeted release of active compounds from TCM at disease sites to increase their concentrations in diseased tissues and reduce the number of adverse effects. Here, we review “internal stimulus–responsive NFs” (based on pH and redox status) and “external stimulus–responsive NFs” (based on light and magnetic fields) and focus on their application for active compounds from TCM against tumors and infectious diseases, to further boost the development of TCM in modern medicine.

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