scholarly journals Microstructural Dynamics of the Myocardium: Orientation of the Muscle Fibers and Occurrence of Cardiomyopathies

2022 ◽  
Vol 2022 ◽  
pp. 1-9
Author(s):  
René Thierry Djoumessi ◽  
François Beceau Pelap
Keyword(s):  
Residual Stress ◽  
Compression Test ◽  
Muscle Fibers ◽  
Orientation Angle ◽  
Tissue Level ◽  
Heart Tissue ◽  
Congenital Diseases ◽  
Organ Level ◽  
Stress States ◽  
The Impact

This paper considers the Holzapfel–Ogden (HO) model to examine the behavior of the left ventricle myocardium. At the tissue level, we analyze the contributions of the orientation angle of muscle fibers (MFs) and investigate their effects on the occurrence of certain cardiomyopathies and congenital diseases at the organ level. Knowing the importance of myocardial microstructure on cardiac function, we vary the angle between the direction of collagen sheets and MFs in all layers of the myocardium (from epicardium to endocardium) to model the effects of tilted MFs. Based on the HO model in which the directions of the fibers are orthogonal and using the strain energy of HO, we construct a tensile-compression test and simulate the dynamics of a cubic sample. We recover the authors’ results exhibiting the existence of residual stresses in various directions. Then, we modify the energy of HO slightly to assess the impact of the same stress states on the system with tilted MFs. A numerical tensile-compression test performed on this new cubic sample shows that, in certain directions, the heart tissue is more resistant to shear deformations in some planes than in others. Moreover, it appears that the residual stress is smaller as the angle of orientation of the MFs is small. Furthermore, we observe that the residual stress is greater in the new model compared to the normal HO model. This could affect the heart muscle at the organ level leading to hypertrophied/dilated cardiomyopathy.

Method development for the determination of textural properties of sugar beet roots

2019 ◽  
pp. 392-400 ◽  
Author(s):  
Gunnar Kleuker ◽  
Christa M. Hoffmann
Keyword(s):  
Sugar Beet ◽  
Compression Test ◽  
Storage Period ◽  
Textural Properties ◽  
Small Sample ◽  
Root Tip ◽  
Flexural Test ◽  
Sample Distribution ◽  
The Impact

The harvest of sugar beet leads to root tip breakage and surface damage through mechanical impacts, which increase storage losses. For the determination of textural properties of sugar beet roots with a texture analyzer a reliable method description is missing. This study aimed to evaluate the impact of washing, soil tare, storage period from washing until measurement, sample distribution and number of roots on puncture and compression measurements. For this purpose, in 2017 comprehensive tests were conducted with sugar beet roots grown in a greenhouse. In a second step these tests were carried out with different Beta varieties from a field trial, and in addition, a flexural test was included. Results show that the storage period after washing and the sample distribution had an influence on the puncture and compression strength. It is suggested to wash the roots by hand before the measurement and to determine the strength no later than 48 h after washing. For reliable and comparable results a radial distribution of measurement points around the widest circumference of the root is recommended for the puncture test. The sample position of the compression test had an influence on the compressive strength and therefore, needs to be clearly defined. For the puncture and the compression test it was possible to achieve stable results with a small sample size, but with increasing heterogeneity of the plant stand a higher number of roots is required. The flexural test showed a high variability and is, therefore, not recommended for the analysis of sugar beet textural properties.

scholarly journals Numerical Investigation on the Ultimate Strength of Box Beams with Impact Damage

2020 ◽  
Author(s):  
Wei Xu ◽  
C. Guedes Soares
Keyword(s):  
Residual Stress ◽  
Ultimate Strength ◽  
Impact Damage ◽  
Ship Hulls ◽  
Four Point Bending ◽  
Impact Location ◽  
Box Beam ◽  
Box Beams ◽  
Fracture Damage ◽  
The Impact

AbstractThe objective of this paper is to study the residual ultimate strength of box beams with impact-induced damage, as a model of what may occur in ship hulls. The bottom and side plates of ship hulls can suffer denting or fracture damage due to grounding, collision and other contacts during the ship’s service life and these impact-induced damages could result in considerable strength degradation. Box beams are firstly subjected to impact loading and then four-point bending loading is imposed on the damaged structures to assess the residual strength using ANSYS/LS_DYNA. The ultimate moment and collapse modes are discussed considering the effect of impact location. The impact-induced deformation is introduced in the four-point bending simulation, and the impact-induced stress is included or not to determine the effect of residual stress and distortion after impact. It is shown that impact location has significant influence on the residual ultimate bending moment of the damaged box beam providing that the impact energy is kept constant. The collapse modes also change when the impactor strikes on different locations. Damaged hard corner and inclined neutral axes might explain the reduction of ultimate strength and diverse collapse modes. The residual stress in the box beam after impact may increase or decrease the ultimate strength depending on impact location.

scholarly journals Statistical analysis of the reproducibility of residual stress measurements in cold extruded parts

2021 ◽  
Author(s):  
Fabian Jaeger ◽  
Alessandro Franceschi ◽  
Holger Hoche ◽  
Peter Groche ◽  
Matthias Oechsner
Keyword(s):  
Residual Stress ◽  
Statistical Analysis ◽  
Stress Measurement ◽  
Industrial Applications ◽  
Cold Extrusion ◽  
X Ray Diffraction ◽  
Forming Process ◽  
X Ray ◽  
Stress States ◽  
Key Aspects

AbstractCold extruded components are characterized by residual stresses, which originate from the experienced manufacturing process. For industrial applications, reproducibility and homogeneity of the final components are key aspects for an optimized quality control. Although striving to obtain identical deformation and surface conditions, fluctuation in the manufacturing parameters and contact shear conditions during the forming process may lead to variations of the spatial residual stress distribution in the final product. This could lead to a dependency of the residual stress measurement results on the relative axial and circumferential position on the sample. An attempt to examine this problem is made by the employment of design of experiments (DoE) methods. A statistical analysis of the residual stress results generated through X-Ray diffraction is performed. Additionally, the ability of cold extrusion processes to generate uniform stress states is analyzed on specimens of austenitic stainless steel 1.4404 and possible correlations with the pre-deformed condition are statistically examined. Moreover, the influence of the coating, consisting of oxalate and a MoS2 based lubricant, on the X-Ray diffraction measurements of the surface is investigated.

scholarly journals Study on improvement of prefolded energy absorption device to constant resistance and its mechanical properties

2021 ◽  
Vol 104 (3) ◽  
pp. 003685042110368
Author(s):  
Dong An ◽  
Jiaqi Song ◽  
Hailiang Xu ◽  
Jingzong Zhang ◽  
Yimin Song ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Energy Absorption ◽  
Compression Test ◽  
Side Wall ◽  
Concave Side ◽  
Displacement Curve ◽  
Static Compression ◽  
Constant Resistance ◽  
The Impact ◽  
Force Displacement

When the rock burst occurs, energy absorption support is an important method to solve the impact failure. To achieve constant resistance performance of energy absorption device, as an important component of the support, the mechanical properties of one kind of prefolded tube is analyzed by quasi-static compression test. The deformation process of compression test is simulated by ABAQUS and plastic strain nephogram of the numerical model are studied. It is found that the main factors affecting the fluctuation of force-displacement curve is the stiffness of concave side wall. The original tube is improved to constant resistance by changing the side wall. The friction coefficient affects the folding order and form of the energy absorbing device. Lifting the concave side wall stiffness can improve the overall stiffness of energy absorption device and slow down the falling section of force-displacement curve. It is always squeezed by adjacent convex side wall in the process of folding, with large plastic deformation. Compared with the original one, the improved prefolded tube designed in this paper can keep the maximum bearing capacity ( Pmax), increase the total energy absorption ( E), improve the specific energy absorption (SEA), and decrease the variance ( S2) of force-displacement curve.

scholarly journals Use of the AE Effect to Determine the Stresses State in AAC Masonry Walls under Compression

Materials ◽  
2021 ◽  
Vol 14 (13) ◽  
pp. 3459
Author(s):  
Radosław Jasiński ◽  
Krzysztof Stebel ◽  
Paweł Kielan
Keyword(s):  
Ultrasonic Waves ◽  
Image Correlation ◽  
Masonry Walls ◽  
Acceptable Error ◽  
Compressive Stresses ◽  
Deformation State ◽  
Hydrostatic Stresses ◽  
Stress States ◽  
The Impact ◽  
Masonry Units

Safety and reliability of constructions operated are predicted using the known mechanical properties of materials and geometry of cross-sections, and also the known internal forces. The extensometry technique (electro-resistant tensometers, wire gauges, sensor systems) is a common method applied under laboratory conditions to determine the deformation state of a material. The construction sector rarely uses ultrasonic extensometry with the acoustoelastic (AE) method which is based on the relation between the direction of ultrasonic waves and the direction of normal stresses. It is generally used to identify stress states of machine or vehicles parts, mainly made of steel, characterized by high homogeneity and a lack of inherent internal defects. The AE effect was detected in autoclaved aerated concrete (AAC), which is usually used in masonry units. The acoustoelastic effect was used in the tests described to identify the complex stress state in masonry walls (masonry units) made of AAC. At first, the relationships were determined for mean hydrostatic stresses P and mean compressive stresses σ3 with relation to velocities of the longitudinal ultrasonic wave cp. These stresses were used to determine stresses σ3. The discrete approach was used which consists in analyzing single masonry units. Changes in velocity of longitudinal waves were identified at a test stand to control the stress states of an element tested by the digital image correlation (DIC) technique. The analyses involved density and the impact of moisture content of AAC. Then, the method was verified on nine walls subjected to axial compression and the model was validated with the FEM micromodel. It was demonstrated that mean compressive stresses σ3 and hydrostatic stresses, which were determined for the masonry using the method considered, could be determined even up to ca. 75% of failure stresses at the acceptable error level of 15%. Stresses σ1 parallel to bed joints were calculated using the known mean hydrostatic stresses and mean compressive stresses σ3.

scholarly journals Concept for controlled adjustment of residual stress states in semi-finished products by gradation extrusion

2021 ◽  
Author(s):  
René Selbmann ◽  
Markus Baumann ◽  
Mateus Dobecki ◽  
Markus Bergmann ◽  
Verena Kräusel ◽  
...  
Keyword(s):  
Residual Stress ◽  
Stress Distribution ◽  
Experimental Tests ◽  
Residual Stress Distribution ◽  
Forming Process ◽  
Compressive Stresses ◽  
Energy Consuming ◽  
Stress States ◽  
Set Up ◽  
Time And Energy

AbstractThe residual stress distribution in extruded components and wires after a conventional forming process is frequently unfavourable for subsequent processes, such as bending operations. High tensile residual stresses typically occur near the surface of the wire and thus limit further processability of the material. Additional heat treatment operations or shot peening are often inserted to influence the residual stress distribution in the material after conventional manufacturing. This is time and energy consuming. The research presented in this paper contains an approach to influence the residual stress distribution by modifying the forming process for wire-like applications. The aim of this process is to lower the resulting tensile stress levels near the surface or even to generate compressive stresses. To achieve these residual compressive stresses, special forming elements are integrated in the dies. These modifications in the forming zone have a significant influence on process properties, such as degree of deformation and deformation direction, but typically have no influence on the diameter of the product geometry. In the present paper, the theoretical approach is described, as well as the model set-up, the FE-simulation and the results of the experimental tests. The characterization of the residual stress states in the specimen was carried out by X-ray diffraction using the sin2Ψ method.

Residual Stresses in Intrinsic UD-CFRP-Steel-Laminates - Experimental Determination, Identification of Sources, Effects and Modification Approaches

2015 ◽  
Vol 825-826 ◽  
pp. 369-376 ◽  
Author(s):  
Robert Prussak ◽  
Daniel Stefaniak ◽  
Christian Hühne ◽  
Michael Sinapius
Keyword(s):  
Mechanical Properties ◽  
Residual Stress ◽  
Tensile Strength ◽  
Epoxy Composite ◽  
Thermal Residual Stress ◽  
Fiber Metal Laminates ◽  
Fiber Metal ◽  
Impact Energies ◽  
The Impact ◽  
Specific Impact

This paper focuses on the reduction of process-related thermal residual stress in fiber metal laminates and its impact on the mechanical properties. Different modifications during fabrication of co-cure bonded steel/carbon epoxy composite hybrid structures were investigated. Specific examinations are conducted on UD-CFRP-Steel specimens, modifying temperature, pressure or using a thermal expansion clamp during manufacturing. The impact of these parameters is then measured on the deflection of asymmetrical specimens or due yield-strength measurements of symmetrical specimens. The tensile strength is recorded to investigate the effect of thermal residual stress on the mechanical properties. Impact tests are performed to determine the influence on resulting damage areas at specific impact energies. The experiments revealed that the investigated modifications during processing of UD-CFRP-Steel specimens can significantly lower the thermal residual stress and thereby improve the tensile strength.

A Method for Evaluating Intensity of Water Cavitation Peening Processing

2011 ◽  
Vol 675-677 ◽  
pp. 747-750
Author(s):  
B. Han ◽  
Dong Ying Ju ◽  
Xiao Guang Yu
Keyword(s):  
Residual Stress ◽  
Process Capability ◽  
Diffraction Method ◽  
Spring Steel ◽  
Bubble Collapse ◽  
Plastic Layer ◽  
Process Conditions ◽  
X Ray Diffraction ◽  
Near Surface ◽  
The Impact

Water cavitation peening (WCP) with aeration, namely, a new ventilation nozzle with aeration is adopted to improve the process capability of WCP by increasing the impact pressure induced by the bubble collapse on the surface of components. In this study, in order to investigate the process capability of the WCP with aeration a standard N-type almen strips of spring steel SAE 1070 was treated byWCP with various process conditions, and the arc height value and the residual stress in the superficial layers were measured by means of the Almen-scale and X-ray diffraction method, respectively. The optimal fluxes of aeration and the optimal standoff distances were achieved. The maximum of arc height value reach around 150μm. The depth of plastic layer observed from the results of residual stresses is up to 150μm. The results verify the existence of macro-plastic strain in WCP processing. The distributions of residual stress in near-surface under different peening intensity can provide a reference for engineers to decide the optimal process conditions of WCP processing.

scholarly journals Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Arunabh Choudhury ◽  
Taj Mohammad ◽  
Nikhil Samarth ◽  
Afzal Hussain ◽  
Md. Tabish Rehman ◽  
...  
Keyword(s):  
Noncovalent Interactions ◽  
Md Simulations ◽  
Telomere Maintenance ◽  
Nucleotide Polymorphisms ◽  
Telomeric Dna ◽  
Congenital Diseases ◽  
Ob Fold ◽  
Significant Conformational Change ◽  
The Stability ◽  
The Impact

AbstractConserved telomere maintenance component 1 (CTC1) is an important component of the CST (CTC1-STN1-TEN1) complex, involved in maintaining the stability of telomeric DNA. Several non-synonymous single-nucleotide polymorphisms (nsSNPs) in CTC1 have been reported to cause Coats plus syndrome and Dyskeratosis congenital diseases. Here, we have performed sequence and structure analyses of nsSNPs of CTC1 using state-of-the-art computational methods. The structure-based study focuses on the C-terminal OB-fold region of CTC1. There are 11 pathogenic mutations identified, and detailed structural analyses were performed. These mutations cause a significant disruption of noncovalent interactions, which may be a possible reason for CTC1 instability and consequent diseases. To see the impact of such mutations on the protein conformation, all-atom molecular dynamics (MD) simulations of CTC1-wild-type (WT) and two of the selected mutations, R806C and R806L for 200 ns, were carried out. A significant conformational change in the structure of the R806C mutant was observed. This study provides a valuable direction to understand the molecular basis of CTC1 dysfunction in disease progression, including Coats plus syndrome.

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