scholarly journals Hypothalamic Lipoma: Outcome of an Intracranial Developmental Lesion

2022 ◽  
Vol 2022 ◽  
pp. 1-8
Author(s):  
Ali Alkhaibary ◽  
Noura Alsubaie ◽  
Ahoud Alharbi ◽  
Noor Alghanim ◽  
Laila Baydhi ◽  
...  
Keyword(s):  
Resonance Imaging ◽  
Electronic Archive ◽  
Contrast Administration ◽  
Radiological Features ◽  
Computed Tomography Images ◽  
Benign Nature ◽  
Neuroradiological Diagnosis ◽  
Peripheral Enhancement ◽  
Development Methods ◽  
Neuroimaging Techniques

Background. Hypothalamic lipomas are benign developmental lesions that tend to be discovered incidentally. This article describes the radiological features, outcome, and the postulated theories behind hypothalamic lipomas development. Methods. The electronic archive of neurosurgery was retrospectively reviewed. All patients with a neuroradiological diagnosis of hypothalamic lipoma, between 2005 and 2020, were included. Results. Out of 246 patients with intracranial lipomas, a total of six patients with hypothalamic lipomas have been identified. On computed tomography images, one of the hypothalamic lipomas demonstrated calcification. On magnetic resonance imaging, peripheral enhancement after contrast administration was noted in one of the lesions. Considering the benign nature of the lesions, neurosurgical intervention was not indicated. Conclusion. The majority of patients with hypothalamic lipomas are asymptomatic and undergo brain imaging for other indications. Although uncommon, such developmental lesions can be identified in the general population, especially with the advancement of neuroimaging techniques.

Intracranial parenchymal schwannoma

1993 ◽  
Vol 79 (2) ◽  
pp. 217-222 ◽  
Author(s):  
Gian Piero Casadei ◽  
Takashi Komori ◽  
Bernd W. Scheithauer ◽  
Gary M. Miller ◽  
Joseph E. Parisi ◽  
...  
Keyword(s):  
Parietal Lobe ◽  
Clinical Course ◽  
Cystic Degeneration ◽  
Resonance Imaging ◽  
Imaging Studies ◽  
Content Type ◽  
Imaging Characteristics ◽  
Benign Nature ◽  
Peripheral Enhancement

✓ The clinical, radiological, and pathological features of nine cases of intracranial parenchymal schwannoma are described. The clinical course in four patients 23 years of age or younger mirrored the indolent nature of this neoplasm. Imaging studies included computerized tomography in eight patients and magnetic resonance imaging in three. The lesions were well demarcated with only mild surrounding edema. Five tumors were deep within the temporoparieto-occipital region, three were in the cerebellum, and one lay peripherally in the parietal lobe. Over two-thirds of the nine tumors were either cystic (five) or contained areas of cystic degeneration (two). One lesion was frankly hemorrhagic. A variety of imaging characteristics and contrast enhancement patterns were observed, including those of a cyst with a mural nodule and peripheral enhancement. Of the four solid neoplasms, two enhanced homogeneously while the other two demonstrated heterogeneous enhancement. Six tumors were resected totally. The follow-up period ranging from 2 months to 2 years has shown no recurrences. Microscopically, immunohistochemically, and ultrastructurally, the tumors were indistinguishable from peripheral schwannomas. A possible mechanism underlying the histogenesis of these rare lesions is discussed. The importance of recognizing this tumor is stressed, particularly in younger patients, given its benign nature, radiological resemblance to other tumors such as pilocytic astrocytoma, and favorable response to resection.

scholarly journals Can DWI-MRI be an alternative to DCE-MRI in the diagnosis of troublesome breast lesions?

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Lamiaa Mohamed Bassam Hashem ◽  
Sherihan W. Y. Gareer ◽  
Aya Mohamed Bassam Hashem ◽  
Sherihan Fakhry ◽  
Yasmin Mounir Tohamey
Keyword(s):  
Problem Solver ◽  
Breast Lesions ◽  
Diffusion Weighted Mri ◽  
Resonance Imaging ◽  
Contrast Administration ◽  
Dce Mri ◽  
Water Diffusivity ◽  
Contrast Enhanced ◽  
Mri Study ◽  
Established Technique

Abstract Background Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has always been a problem solver in troublesome breast lesions. Despite its many advantages, the encountered low specificity results in unnecessary biopsies. Diffusion-weighted MRI (DW-MRI) is a well-established technique that helps in characterizing breast lesions according to their water diffusivity. So this work aimed to assess the diagnostic performance of DW-MRI in troublesome breast lesions and see if it can replace DCE-MRI study. Results In our prospective study, we included 86 patients with mammography and/or ultrasound-detected 90 probably benign or probably malignant (BIRADS 3 or 4) breast lesions. Among the studied cases, 49/90 lesions were benign, and 41/90 were malignant. Combined analysis of morphological and kinetic findings in DCE-MRI had achieved the highest sensitivity of 95.1%. DW-MRI alone was less sensitive (73.2%) yet more specific (83.7%) than DCE-MRI (77.6%). Diagnostic accuracy of DCE-MRI was higher (85.6%) as compared to DW-MRI which was (78.9%). Conclusion DCE-MRI is the cornerstone in the workup of troublesome breast lesions. DW-MRI should not be used as supplementary tool unless contrast administration is contraindicated. Combining both DCE-MRI and DW-MRI is the ultimate technique for better lesion evaluation.

scholarly journals Cardiac Magnetic Resonance Imaging - A Predictor Tool for Sudden Cardiac Death

1970 ◽  
Vol 6 (2) ◽  
pp. 90-92
Author(s):  
Nilufar Fatema ◽  
Md Abu Siddique ◽  
Sajal Krishna Banerjee ◽  
Syde Ali Ahsan ◽  
Fazlur Rahman ◽  
...  
Keyword(s):  
Sudden Cardiac Death ◽  
Magnetic Resonance ◽  
Myocardial Fibrosis ◽  
Cardiac Death ◽  
Resonance Imaging ◽  
Gadolinium Enhancement ◽  
Gadolinium Contrast ◽  
Contrast Administration ◽  
Malignant Arrhythmia ◽  
Prognostic Importance

Cardiovascular magnetic resonance (CMR) detects myocardial fibrosis, which appears as late gadolinium enhancement (LGE) after gadolinium contrast administration and may convey prognostic importance. Myocardial fibrosis is the source of malignant arrhythmia like ventricular tachycardia or ventricular fibrillation. Sudden cardiac death occurs in these group patients. By detecting myocardial fibrosis we can select these groups of patients for implantable cardioverter defibrillator. Thus sudden cardiac death can be prevented in some extent.Keywords: Cardiac MRI; Sudden cardiac death. DOI: 10.3329/uhj.v6i2.7253University Heart Journal Vol. 6, No. 2, July 2010 pp.90-92

scholarly journals MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas

2020 ◽  
Vol 79 (8) ◽  
pp. 855-862
Author(s):  
Vilde Elisabeth Mikkelsen ◽  
Hong Yan Dai ◽  
Anne Line Stensjøen ◽  
Erik Magnus Berntsen ◽  
Øyvind Salvesen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Overall Survival ◽  
Magnetic Resonance ◽  
Tumor Biology ◽  
Mgmt Promoter Methylation ◽  
Conventional Magnetic Resonance Imaging ◽  
Wild Type ◽  
Resonance Imaging ◽  
Radiological Features ◽  
Mgmt Promoter

Abstract O6-methylguanine DNA methyltransferase (MGMT) promoter methylation is an important favorable predictive marker in patients with glioblastoma (GBM). We hypothesized that MGMT status could be a surrogate marker of pretreatment tumor biology observed as histopathological and radiological features. Apart from some radiological studies aiming to noninvasively predict the MGMT status, few studies have investigated relationships between MGMT status and phenotypical tumor biology. We have therefore aimed to investigate such relationships in 85 isocitrate dehydrogenase (IDH) wild-type GBMs. MGMT status was determined by methylation-specific PCR and was assessed for associations with 22 histopathological features, immunohistochemical proliferative index and microvessel density measurements, conventional magnetic resonance imaging characteristics, preoperative speed of tumor growth, and overall survival. None of the investigated histological or radiological features were significantly associated with MGMT status. Methylated MGMT status was a significant independent predictor of improved overall survival. In conclusion, our results suggest that MGMT status is not related to the pretreatment phenotypical biology in IDH wild-type GBMs. Furthermore, our findings suggest the survival benefit of MGMT methylated GBMs is not due to an inherently less aggressive tumor biology, and that conventional magnetic resonance imaging features cannot be used to noninvasively predict the MGMT status.

scholarly journals A solitary fibrous tumor/hemangiopericytoma of the fourth ventricle: case report and literature review

2019 ◽  
Vol 47 (12) ◽  
pp. 6349-6355
Author(s):  
Han Yang ◽  
Yuxin Zhang ◽  
Ting Zheng ◽  
Cao Li ◽  
Guangcai Tang ◽  
...  
Keyword(s):  
Literature Review ◽  
Fourth Ventricle ◽  
Solid Mass ◽  
Resonance Imaging ◽  
Radiological Findings ◽  
Black And White ◽  
Radiological Features ◽  
The Central Nervous System ◽  
Fibrous Tumor ◽  
Progressive Weakness

Solitary fibrous tumors/hemangiopericytomas (SFTs/HPCs) are rare in the central nervous system and intraventricular SFTs/HPCs are even rarer. We present a clinical case of SFT/HPC that was located in the fourth ventricle and performed a literature review of radiological findings of SFT/HPC. The patient was a 52-year-old man who presented to our hospital with dizziness and progressive weakness in his left extremities. Computed tomography and magnetic resonance imaging showed an irregular-shaped mass in the fourth ventricle. The upper anterior and lower posterior parts of the mass showed different densities and signal intensities, which formed a black and white sign. The upper anterior and lower posterior parts of the mass were enhanced to different degrees, and showed heterogeneous reversed enhancement. The patient underwent surgical resection and the mass was histologically confirmed to be an SFT/HPC. SFTs/HPCs of the fourth ventricle are rare, but show characteristic radiological presentations. In the present case, we observed a solid mass with flow voids, black and white sign, and heterogeneously reversed enhancement in the fourth ventricle. Collectively, these radiological features suggested the diagnosis of SFT/HPC.

scholarly journals Imaging of compound palmar ganglion with pathologic correlation

2014 ◽  
Vol 18 (1) ◽  
Author(s):  
Sourav Talukder ◽  
Anindya Bandyopadhay ◽  
Shamick Biswas ◽  
Sumit Chakraborty ◽  
Suchismita Chakrabarti
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Common Site ◽  
Radiological Features ◽  
Flexor Tenosynovitis ◽  
Compound Palmar Ganglion ◽  
Extrapulmonary Manifestation ◽  
Palmar Aspect

Compound palmar ganglion, or chronic flexor tenosynovitis, most commonly of tuberculousorigin, is a rare extrapulmonary manifestation of tuberculosis (TB). The flexor synovialsheath is not a common site for TB but, once involved, causes rapid involvement of all flexortendons. We discuss the case of a 70-year-old farmer who presented to us with pain and progressive swelling of the palmar aspect of the wrist. On clinical examination, swelling both above and below the proximal wrist crease was found, with positive cross-fluctuation. Onultrasonography and magnetic resonance imaging, features suggestive of compound palmarganglion were present. The patient underwent surgical resection (extensive tenosynovectomy)and chemotherapy. Post-operative histopatholgical findings correlated with the radiological features.

scholarly journals Neurodegeneration in Schizophrenia: Evidence fromIn VivoNeuroimaging Studies

2007 ◽  
Vol 7 ◽  
pp. 135-143 ◽  
Author(s):  
John G. Csernansky
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Gray Matter ◽  
Neurodevelopmental Disorder ◽  
Resonance Imaging ◽  
Cellular Mechanisms ◽  
Temporal Lobes ◽  
Non Invasive ◽  
The Brain ◽  
Neuroimaging Techniques

Although schizophrenia is primarily considered to be a neurodevelopmental disorder, there is a growing consensus that the disorder may also involve neurodegeneration. Recent research using non-invasive neuroimaging techniques, such as magnetic resonance imaging, suggests that some patients with schizophrenia show progressive losses of gray matter in the frontal and temporal lobes of the brain. The cellular mechanisms responsible for such gray matter losses are unknown, but have been hypothesized to involve abnormal increases in apoptosis.

Cerebellopontine angle lipoma

1993 ◽  
Vol 107 (6) ◽  
pp. 553-555 ◽  
Author(s):  
L. J. O'Keeffe ◽  
R. T. Ramsden ◽  
A. R. Birzgalis
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Acoustic Neuroma ◽  
Cerebellopontine Angle ◽  
Resonance Imaging ◽  
Radiological Features

A case of a cerebellopontine angle lipoma is presented with a typical clinical, audiometric and radiological features of an acoustic neuroma. The correct pre-operative diagnosis was elusive even with the aid of magnetic resonance imaging.

scholarly journals Emerging Trends in Neuroimaging of Epilepsy

2021 ◽  
Vol 21 (2) ◽  
pp. 79-82
Author(s):  
Neda Bernasconi ◽  
Irene Wang
Keyword(s):  
Magnetic Resonance Imaging ◽  
Machine Learning ◽  
Magnetic Resonance ◽  
Brain Structure ◽  
Structure And Function ◽  
Resonance Imaging ◽  
Emerging Trends ◽  
Brain Structure And Function ◽  
And Function ◽  
Neuroimaging Techniques

Neuroimaging techniques, particularly magnetic resonance imaging, yield increasingly sophisticated markers of brain structure and function. Combined with ongoing developments in machine learning, these methods refine our abilities to detect subtle epileptogenic lesions and develop reliable prognostics.

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