Alpha-smooth Muscle Actin Expression in the Stroma Predicts Resistance to Trastuzumab in Patients with Early-stage HER2-positive Breast Cancer

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-21-2103 ◽

2021 ◽

Author(s):

Ioannis A. Vathiotis ◽

Myrto K. Moutafi ◽

Prajan Divakar ◽

Thazin Nwe Aung ◽

Tao Qing ◽

...

Keyword(s):

Breast Cancer ◽

Smooth Muscle ◽

Early Stage ◽

Smooth Muscle Actin ◽

Muscle Actin ◽

Alpha Smooth Muscle Actin ◽

Her2 Positive ◽

Her2 Positive Breast Cancer ◽

Actin Expression ◽

Positive Breast Cancer

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Abstract 339: Resistance to trastuzumab is associated with alpha-smooth muscle actin expression in the stroma of patients with HER2+ breast cancer

10.1158/1538-7445.am2021-339 ◽

2021 ◽

Author(s):

Ioannis A. Vathiotis ◽

Myrto K. Moutafi ◽

Prajan Divakar ◽

Thazin Nwe Aung ◽

Aileen Fernandez ◽

...

Keyword(s):

Breast Cancer ◽

Smooth Muscle ◽

Smooth Muscle Actin ◽

Muscle Actin ◽

Alpha Smooth Muscle Actin ◽

Her2 Breast Cancer ◽

Actin Expression

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FDA approves neratinib for extended adjuvant treatment of early stage HER2-positive breast cancer

Case Medical Research ◽

10.31525/fda1-ucm567259.htm ◽

2017 ◽

Author(s):

Keyword(s):

Breast Cancer ◽

Adjuvant Treatment ◽

Early Stage ◽

Her2 Positive ◽

Her2 Positive Breast Cancer ◽

Positive Breast Cancer

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Faculty Opinions recommendation of TGF-beta1 and integrin synergistically facilitate the differentiation of rat podocytes by increasing alpha-smooth muscle actin expression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1040492.489467 ◽

2006 ◽

Author(s):

Giulio Gabbiani

Keyword(s):

Smooth Muscle ◽

Smooth Muscle Actin ◽

Muscle Actin ◽

Alpha Smooth Muscle Actin ◽

Actin Expression

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Faculty Opinions recommendation of TNF-alpha suppresses alpha-smooth muscle actin expression in human dermal fibroblasts: an implication for abnormal wound healing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1087546.540606 ◽

2007 ◽

Author(s):

Giulio Gabbiani

Keyword(s):

Wound Healing ◽

Smooth Muscle ◽

Smooth Muscle Actin ◽

Dermal Fibroblasts ◽

Tnf Alpha ◽

Human Dermal Fibroblasts ◽

Muscle Actin ◽

Alpha Smooth Muscle Actin ◽

Actin Expression

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Faculty Opinions recommendation of Adjuvant lapatinib for women with early-stage HER2-positive breast cancer: a randomised, controlled, phase 3 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717969433.793480577 ◽

2013 ◽

Author(s):

Nancy Lin ◽

Ines Vaz-Luis

Keyword(s):

Breast Cancer ◽

Early Stage ◽

Her2 Positive ◽

Phase 3 ◽

Her2 Positive Breast Cancer ◽

Randomised Controlled ◽

Positive Breast Cancer

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Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials

The Lancet Oncology ◽

10.1016/s1470-2045(21)00288-6 ◽

2021 ◽

Vol 22 (8) ◽

pp. 1139-1150

Author(s):

Rosie Bradley ◽

Jeremy Braybrooke ◽

Richard Gray ◽

Robert Hills ◽

Zulian Liu ◽

...

Keyword(s):

Breast Cancer ◽

Early Stage ◽

Meta Analysis ◽

Randomised Trials ◽

Her2 Positive ◽

Her2 Positive Breast Cancer ◽

Positive Breast Cancer

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Regulation of Alpha-Smooth Muscle Actin Expression in Adult Cardiomyocytes through a Tyrosine Kinase Signal Transduction Pathway

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1995.tb17422.x ◽

1995 ◽

Vol 752 (1 Cardiac Growt) ◽

pp. 192-201 ◽

Cited By ~ 4

Author(s):

H. EID ◽

J. H. CHEN ◽

A. J. BOLD

Keyword(s):

Signal Transduction ◽

Smooth Muscle ◽

Tyrosine Kinase ◽

Smooth Muscle Actin ◽

Signal Transduction Pathway ◽

Muscle Actin ◽

Transduction Pathway ◽

Alpha Smooth Muscle Actin ◽

Adult Cardiomyocytes ◽

Actin Expression

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Inhibitory effect of nicotine on collagen and alpha‐smooth muscle actin expression in cardiac fibroblasts

The FASEB Journal ◽

10.1096/fasebj.22.1_supplement.1130.20 ◽

2008 ◽

Vol 22 (S1) ◽

Author(s):

David Lu ◽

Utako Yokoyama ◽

Paul A. Insel

Keyword(s):

Smooth Muscle ◽

Cardiac Fibroblasts ◽

Smooth Muscle Actin ◽

Inhibitory Effect ◽

Muscle Actin ◽

Alpha Smooth Muscle Actin ◽

Actin Expression

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Impact of timing of trastuzumab initiation on long-term outcome of patients with early-stage HER2-positive breast cancer: the “one thousand HER2 patients” project

British Journal of Cancer ◽

10.1038/s41416-018-0114-x ◽

2018 ◽

Vol 119 (3) ◽

pp. 374-380 ◽

Cited By ~ 2

Author(s):

Giuseppe Gullo ◽

Naomi Walsh ◽

David Fennelly ◽

Reetesh Bose ◽

Janice Walshe ◽

...

Keyword(s):

Breast Cancer ◽

Early Stage ◽

Her2 Positive ◽

Term Outcome ◽

Long Term Outcome ◽

Her2 Positive Breast Cancer ◽

The One ◽

Positive Breast Cancer

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TP53 upregulates α‑smooth muscle actin expression in tamoxifen‑resistant breast cancer cells

Oncology Reports ◽

10.3892/or.2018.6910 ◽

2018 ◽

Cited By ~ 1

Author(s):

Sangmin Kim ◽

Daeun You ◽

Yisun Jeong ◽

Jonghan Yu ◽

Seok Kim ◽

...

Keyword(s):

Breast Cancer ◽

Smooth Muscle ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Smooth Muscle Actin ◽

Muscle Actin ◽

Tamoxifen Resistant ◽

Actin Expression

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