Difference in the Role of Loss of Heterozygosity at 10p15 (KLF6 Locus) in Colorectal Carcinogenesis between Sporadic and Familial Adenomatous Polyposis and Hereditary Nonpolyposis Colorectal Cancer Patients

Oncology ◽  
2006 ◽  
Vol 71 (1-2) ◽  
pp. 131-135 ◽  
Author(s):  
Michiko Miyaki ◽  
Tatsuro Yamaguchi ◽  
Takeru Iijima ◽  
Nobuaki Funata ◽  
Takeo Mori
Keyword(s):  
Colorectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Cancer Patients ◽  
Loss Of Heterozygosity ◽  
Hereditary Nonpolyposis Colorectal Cancer ◽  
Colorectal Carcinogenesis ◽  
Adenomatous Polyposis ◽  
Hereditary Nonpolyposis ◽  
Colorectal Cancer Patients

What's New in Hereditary Colorectal Cancer?

2005 ◽  
Vol 129 (11) ◽  
pp. 1380-1384 ◽  
Author(s):  
Jeremy R. Jass
Keyword(s):  
Colorectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Hereditary Nonpolyposis Colorectal Cancer ◽  
Practical Significance ◽  
Adenomatous Polyposis ◽  
Repair Gene ◽  
Attenuated Familial Adenomatous Polyposis ◽  
Dna Repair Gene ◽  
Hereditary Nonpolyposis ◽  
Revised Bethesda Guidelines

Abstract Precancerous polyposes other than classic familial adenomatous polyposis and the condition hereditary nonpolyposis colorectal cancer, or Lynch syndrome, continue to present major diagnostic challenges for the anatomic pathologist. This editorial highlights the practical significance of novel insights and clinical guidelines in the recent literature, as well as in 4 contributions to this edition of the Archives of Pathology & Laboratory Medicine. The first section will address attenuated familial adenomatous polyposis and a newly recognized type of autosomal-recessive adenomatous polyposis associated with the DNA repair gene MYH. The remainder of the editorial discusses the role of the revised Bethesda guidelines in the diagnosis of hereditary nonpolyposis colorectal cancer and concludes with the recently identified serrated pathway syndrome.

scholarly journals Stability of BAT26 in tumours of hereditary nonpolyposis colorectal cancer patients with MSH2 intragenic deletion

2005 ◽  
Vol 14 (1) ◽  
pp. 63-68 ◽  
Author(s):  
Chiara Pastrello ◽  
Silvana Baglioni ◽  
Maria Grazia Tibiletti ◽  
Laura Papi ◽  
Mara Fornasarig ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Hereditary Nonpolyposis Colorectal Cancer ◽  
Intragenic Deletion ◽  
Hereditary Nonpolyposis ◽  
Colorectal Cancer Patients
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