Role of Sympathetic Nerves in Disposition and Metabolism of Intraluminal and Extraluminal Noradrenaline in the Rabbit Ear Artery

1988 ◽  
Vol 25 (5) ◽  
pp. 232-239
Author(s):  
M.G. Venning ◽  
I.S. de la Lande
1997 ◽  
Vol 121 (8) ◽  
pp. 1659-1664 ◽  
Author(s):  
A. L. García-Villalón ◽  
J Padilla ◽  
N Fernández ◽  
L Monge ◽  
B Gómez ◽  
...  

1998 ◽  
Vol 34 (3) ◽  
pp. 123-137 ◽  
Author(s):  
Hiroaki NISHIJIMA ◽  
Ryuji UCHIDA ◽  
Nozomi KAWAKAMI ◽  
Keiichi SHIMAMURA ◽  
Kenji KITAMURA

1970 ◽  
Vol 18 (3) ◽  
pp. 211-216 ◽  
Author(s):  
J. G. WATERSON ◽  
W. R. HUME ◽  
I. S. DE LA LANDE

Acetylcholinesterase and butyrylcholinesterase activities were demonstrated in transverse sections of the rabbit ear artery using a "direct coloring" thiocholine technique. BW 284C51, iso-OMPA and DFP were used as inhibitors, and acetyl and butyrylthiocholine iodides as substrates. Both enzymes caused stain deposits at the medial-adventitial border of the artery, in a region where sympathetic nerves are present. Sections treated to demonstrate acetylcholinesterase showed staining which was lighter than that for butyrylcholinesterase. Degeneration of the sympathetic nerves following superior cervical ganglionectomy virtually abolished stain at the medial-adventitial border. These results provide some support for the evidence of other workers that a cholinergic mechanism may be linked to sympathetic nerve transmission in the rabbit ear artery.


Author(s):  
John T. Dodge ◽  
John A. Bevan

Unlike many peripheral vascular beds, the sympathetic nervous system exerts little control on cerebral blood flow. The contractile response of isolated rabbit middle cerebral artery (MCA) segments to electrical field stimulation of its intramural nerves is less than in a similar-sized artery from the ear. This study was undertaken to characterize and compare the perivascular neuromuscular relationships and innervation density of similar-sized arteries varying in diameter from these two different regional arterial beds to see if there were structural correlates for these functional differences.


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