Retinal Angiomatous Proliferation in an Eye with Cuticular Drusen

Purpose: To report the presence of retinal angiomatous proliferation (RAP) in an eye with cuticular drusen detected by fluorescein and indocyanine green angiography by confocal scanning laser ophthalmoscopy and by spectral-domain optical coherence tomography (SD-OCT). Methods: Case report of a 65-year-old Japanese woman with cuticular drusen. Results: At her first ophthalmic examination, her visual acuity was 20/20 in both eyes. An ophthalmoscopy showed many small subretinal pigment epithelial deposits in both eyes. These deposits had a ‘saw-tooth pattern' in the SD-OCT images. During the follow-up examination, retinal hemorrhages were observed, and fluorescein angiography showed a ‘stars-in-the-sky' appearance and intraretinal neovascularization. The patient was diagnosed with cuticular drusen associated with RAP. Conclusion: We suggest that the cuticular drusen were associated with RAP, so periodic follow-up examinations are needed for patients with cuticular drusen for the early detection and treatment of RAP.

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Long-Term Follow-Up of Scanning Laser Polarimetry and Confocal Scanning Laser Ophthalmoscopy in Normal Tension Glaucoma

Journal of Clinical & Experimental Ophthalmology ◽

10.4172/2155-9570.1000474 ◽

2015 ◽

Vol 06 (05) ◽

Author(s):

Kremmer S ◽

Darwesh S

Keyword(s):

Normal Tension Glaucoma ◽

Scanning Laser ◽

Scanning Laser Ophthalmoscopy ◽

Laser Polarimetry ◽

Confocal Scanning Laser Ophthalmoscopy ◽

Long Term Follow Up ◽

Confocal Scanning ◽

Confocal Scanning Laser

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Longitudinal Analysis of Reticular Drusen Associated with Age-Related Macular Degeneration Using Combined Confocal Scanning Laser Ophthalmoscopy and Spectral-Domain Optical Coherence Tomography Imaging

Ophthalmologica ◽

10.1159/000368168 ◽

2014 ◽

Vol 233 (1) ◽

pp. 35-42 ◽

Cited By ~ 11

Author(s):

Julia S. Steinberg ◽

Jasmin Auge ◽

Monika Fleckenstein ◽

Frank G. Holz ◽

Steffen Schmitz-Valckenberg

Keyword(s):

Optical Coherence Tomography ◽

Macular Degeneration ◽

Age Related Macular Degeneration ◽

Scanning Laser Ophthalmoscopy ◽

Confocal Scanning Laser Ophthalmoscopy ◽

Age Related ◽

Confocal Scanning ◽

Confocal Scanning Laser ◽

Reticular Drusen ◽

Sd Oct

Purpose: To evaluate longitudinal variations of reticular drusen (RDR) in age-related macular degeneration using confocal scanning laser ophthalmoscopy (cSLO), near-infrared reflectance (NIR) and spectral-domain optical coherence tomography (SD-OCT) imaging. Methods: Eighteen eyes of 12 patients with RDR (median observational time 5 months, range 3-10) were included. Changes over time in the en face cSLO NIR images, the identical SD-OCT B scan (simple approach) and the dense SD-OCT volume scans (11 µm between B scans, detailed approach) for 5 preselected RDR lesions were analysed, respectively. Results: Nineteen of 90 (21%) lesions were no longer detectable at the follow-up examination with the simple SD-OCT approach (increase 7/decrease 48/unchanged 15/not gradable 1). By contrast, no disappearance of single lesions was noted for both cSLO (3/8/61/18) and detailed SD-OCT image analysis (67/22/1/0). Within the dense SD-OCT volume scan, a median change of individual lesion height of 10 µm/year was determined. Conclusions: The findings indicate a recordable progression of RDR lesions in lateral and vertical dimensions. Using dense SD-OCT volume scans, individual RDR lesion progression can be quantified and may be applied in future longitudinal studies.

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