Phenotypic Variants of Differentiation-Inducible Friend Leukemia Lines: Isolation and Correlation between Inducibility and Virus Release

2015 ◽  
pp. 37-47 ◽  
Author(s):  
Y. Ikawa ◽  
Y. Inoue ◽  
M. Aida ◽  
R. Kameji ◽  
C. Shibata ◽  
...  
Keyword(s):  
Virus Release ◽  
Friend Leukemia

Recent Studies on a Murine Leukemia Virus Grown in Tissue Culture

1967 ◽  
Vol 25 ◽  
pp. 106-107
Author(s):  
L. Z. de Tkaczevski ◽  
E. de Harven ◽  
C. Friend
Keyword(s):  
Tissue Culture ◽  
Solid Tumors ◽  
Murine Leukemia Virus ◽  
Leukemia Virus ◽  
Supernatant Fluid ◽  
Virus Particles ◽  
Friend Leukemia ◽  
Type C ◽  
Leukemia Viruses ◽  
Murine Leukemia

Despite extensive studies, the correlation between the morphology and pathogenicity of murine leukemia viruses (MLV) has not yet been clarified. The virus particles found in the plasma of leukemic mice belong to 2 distinct groups, 1 or 2% of them being enveloped A particles and the vast majority being of type C. It is generally believed that these 2 types of particles represent different phases in the development of the same virus. Particles of type A have been thought to be an earlier form of type C particles. One of the tissue culture lines established from Friend leukemia solid tumors has provided the material for the present study. The supernatant fluid of the line designated C-1A contains an almost pure population of A particles as illustrated in Figure 1. The ratio is, therefore, the reverse of what is unvariably observed in the plasma of leukemic mice where C particles predominate.

Involvement of GER in Friend leukemia virus assembly in high-pressure frozen cells

1990 ◽  
Vol 48 (3) ◽  
pp. 590-591
Author(s):  
W. Djaczenko ◽  
M. Müller ◽  
A. Benedetto ◽  
G. Carbone
Keyword(s):  
High Pressure ◽  
Virus Assembly ◽  
Leukemia Virus ◽  
Leukemia Cells ◽  
Serial Sections ◽  
Myeloma Cells ◽  
Virus Particles ◽  
Friend Leukemia ◽  
Carbon Coated ◽  
Friend Leukemia Virus

A thickening of ER membranes in murine myeloma cells was attributed by de Harven to the assembly of intracisternal virus particles. We observed similar thickening of GER membranes in Friend leukemia cells (FLC) apparently associated with Friend leukemia virus (FLV) assembly. We reinvestigated the problem of GER involvement in FLV assembly using high pressure cryofixed FLC.FLC (745A clone growing in suspension and FF clone growing in monolayer) were immersed in Hexadecene (Fluka, Switzerland) and rapidly frozen in Balzers HPM 010 freezing machine working at 2200 bar. All cells were freeze substituted at -90°C in 2% OsO4 in absolute acetone. Serial sections cut to avoid misinterpretations due to the geometry of sections, were collected on carbon coated 100 mesh grids.

Effects of hexose starvation and the role of sialic acid in influenza virus release

Virology ◽  
1983 ◽  
Vol 125 (2) ◽  
pp. 324-334 ◽  
Author(s):  
Johanna A. Griffin ◽  
Sukla Basak ◽  
Richard W. Compans
Keyword(s):  
Influenza Virus ◽  
Sialic Acid ◽  
Virus Release

A New Differentiation Inducer of Friend Leukemia Cells, Trichostatic Acid

1985 ◽  
Vol 49 (5) ◽  
pp. 1365-1370 ◽  
Author(s):  
Hajimu Morioka ◽  
Masaru Ishihara ◽  
Misako Takezawa ◽  
Kazuo Hirayama ◽  
Eiichiro Suzuki ◽  
...  
Keyword(s):  
Leukemia Cells ◽  
Friend Leukemia ◽  
Differentiation Inducer

scholarly journals ESCRT Requirements for Murine Leukemia Virus Release

Viruses ◽  
2016 ◽  
Vol 8 (4) ◽  
pp. 103 ◽  
Author(s):  
Christina Bartusch ◽  
Reinhild Prange
Keyword(s):  
Murine Leukemia Virus ◽  
Leukemia Virus ◽  
Virus Release ◽  
Murine Leukemia
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