Body Mass Index as a Risk Factor for Toxicities in Patients with Advanced Soft-Tissue Sarcoma Treated with Trabectedin

Oncology ◽  
2018 ◽  
Vol 95 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Bruno Vincenzi ◽  
Giuseppe Badalamenti ◽  
Grazia Armento ◽  
Marianna Silletta ◽  
Mariella Spalato Ceruso ◽  
...  
2011 ◽  
Vol 104 (10) ◽  
pp. 1544-1550 ◽  
Author(s):  
N Penel ◽  
M V Glabbeke ◽  
S Mathoulin-Pelissier ◽  
I Judson ◽  
S Sleijfer ◽  
...  

2018 ◽  
Vol 69 (7) ◽  
pp. 1842-1845
Author(s):  
Lavinia Stelea ◽  
Izabella Petre ◽  
Marius Craina ◽  
Brigitha Vlaicu ◽  
Alina Sisu ◽  
...  

The aim of this study was to determine if body mass can be considered a risk factor for infertility, and if we can find any correlations between the age values and the FSH and estradiol values, and between the BMI values and the FSH and estradiol values. Our whole sample contains 100 patients splinted in two groups (pregnant patients N1=57 subjects, 57%, and not � pregnant patients N1=43 subjects,43%). In the first part we conducted our analysis on the whole group and after that we focused the analysis on the two groups and we made some comparisons between the groups. We obtained a medium, extremely significant correlation in all scenarios between the age and the FSH values. This is the best association from all the cases which we tested. In all twelve cases we have a positive correlation (r ] 0). As well, we obtained that a BMI value higher than 25can be considered a risk factor for obtaining a pregnancy (p[0.05, RR ] 1, OR]1) . Our study shows that women who have weight problems have much less chances of conceiving a baby, even if they ovulate normally. The risk of infertility increases proportionally to the extra pounds. Irregular ovulation in women is the most common fertility disorder due to obesity disease.


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