A Closer Look at Bleach Baths: Evidence, Tub Size, and Instructions

Dermatology ◽  
2021 ◽  
pp. 1-5
Author(s):  
Erin Collier ◽  
Sophia Sangar ◽  
Amy Shen ◽  
Jeremy Davis

Dilute sodium hypochlorite (bleach) baths have been used in routine care for many dermatologic conditions, namely atopic dermatitis. The benefits of bleach baths in reducing bacterial carriage have been well documented; however, the instructions often require subjective interpretation of bathtub size and may result in varying concentrations of bleach. Herein, we review the evidence for use of bleach baths and provide a method for ensuring that proper bleach concentrations are achieved.

Dermatology ◽  
2021 ◽  
pp. 1-6
Author(s):  
Birgit-Christiane Zyriax ◽  
Matthias Augustin ◽  
Finn Abeck ◽  
Nicole Mohr ◽  
Natalia Kirsten ◽  
...  

<b><i>Background:</i></b> Atopic dermatitis (AD) is a chronic inflammatory skin disease that is often associated with comorbidities and quality of life losses. The implementation of evidence-based preventive measures strengthens patient participation and offers the potential to improve quality of care for AD. <b><i>Objectives:</i></b> To assess adherence to guideline-oriented preventive measures in adult patients with AD in dermatological routine care in Germany. <b><i>Methods:</i></b> The self-responsible application of preventive measures, clinical features, pruritus, disease severity, and duration of disease as well as skin disease-related quality of life were assessed in two independent cross-sectional studies in 2010 and 2017–2019. <b><i>Results:</i></b> Between 2017 and 2019, 706 patients (55.8% female, mean age 41 years) were recruited in a comparable way to the survey in 2010 with 1,678 patients (60.5% female, mean age 38 years). Regular skin care was applied by 99.5% (2010: 94.9%), 90.9% avoided skin irritants (2010: 84.6%), and 80.2% (2010: 61.6%) did not smoke at home. Relaxation techniques were applied by 44.4% (2010: 29.9%). Advice on self-help measures was taken by 36.4% (2010: 27.1%) and 29.2% (2010: 15.4%) attended AD patient education courses. All six preventive measures categorized as obligatory were performed by 13.9% of the patients (2010: 6.7%). Predictors for the number of obligatory preventive measures applied were a high level of education, a longer disease duration, and a lower quality of life. <b><i>Conclusions:</i></b> Although the self-reported use of evidence-based preventive measures in the 2017–2019 study appears to be more frequent than in 2010, important measures are still insufficiently established. Hence, more implementation, including education, is needed to increase the use of guideline-oriented preventive measures.


2019 ◽  
Vol 36 (4) ◽  
pp. 442-447 ◽  
Author(s):  
Sara Majewski ◽  
Tanya Bhattacharya ◽  
Manuela Asztalos ◽  
Benjamin Bohaty ◽  
Katherine C. Durham ◽  
...  

2013 ◽  
Vol 30 (3) ◽  
pp. 308-315 ◽  
Author(s):  
Caitriona Ryan ◽  
Richard E. Shaw ◽  
Clay J. Cockerell ◽  
Shari Hand ◽  
Fred E. Ghali

Author(s):  
Russell L. Steere ◽  
Eric F. Erbe

Thin sheets of acrylamide and agar gels of different concentrations were prepared and washed in distilled water, cut into pieces of appropriate size to fit into complementary freeze-etch specimen holders (1) and rapidly frozen. Freeze-etching was accomplished in a modified Denton DFE-2 freeze-etch unit on a DV-503 vacuum evaporator.* All samples were etched for 10 min. at -98°C then re-cooled to -150°C for deposition of Pt-C shadow- and C replica-films. Acrylamide gels were dissolved in Chlorox (5.251 sodium hypochlorite) containing 101 sodium hydroxide, whereas agar gels dissolved rapidly in the commonly used chromic acid cleaning solutions. Replicas were picked up on grids with thin Foimvar support films and stereo electron micrographs were obtained with a JEM-100 B electron microscope equipped with a 60° goniometer stage.Characteristic differences between gels of different concentrations (Figs. 1 and 2) were sufficiently pronounced to convince us that the structures observed are real and not the result of freezing artifacts.


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