Schlaf‘, Kindlein, schlaf‘: Schlafverhalten von Säuglingen unter Propranolol-Therapie

2021 ◽  
pp. 1-2
Author(s):  
Henning Hamm
Keyword(s):  
Sleep Quality ◽  
Outcome Measures ◽  
Negative Impact ◽  
Behavioral Development ◽  
Sleep Efficiency ◽  
Sleep Pattern ◽  
Control Group ◽  
Infant Sleep ◽  
Sleep Behavior ◽  
Daytime Sleep

Sleep problems are frequently reported in infants treated with propranolol for infantile hemangiomas, possibly serving as a marker for a negative impact on central nervous system function. In this cohort study, we objectively investigate the sleep behavior of infants with infantile hemangiomas on propranolol compared to a healthy, untreated control group. Sleep of propranolol-treated infants and controls was investigated using ankle actigraphy and a 24-h diary for 7–10 days at ages 3 and 6 months. The main outcome measures were the Number of Nighttime Awakenings and Sleep Efficiency. The main secondary outcome measures included 24-hour Total Sleep, daytime sleep behavior, and parent-rated infant sleep quality and behavioral development based on the Brief Infant Sleep Questionnaire (BISQ) and the age-appropriate Ages-and-Stages Questionnaire (ASQ), respectively. Fifty-four term-born infants were included in each cohort. No group difference in any investigated parameter was seen at age 3 months. At age 6 months, the propranolol group exhibited a decrease in Sleep Efficiency and a trend towards an increased Number of Nighttime Awakenings compared to the control group. Treated infants at 6 months also had shorter daytime waking periods. 24-hour Total Sleep was unaffected by propranolol. No negative impact of propranolol on subjective sleep quality and behavioral development was noted. <b>Conclusion:</b> Propranolol exerts a measurable yet mild impact on objectively assessed infants’ sleep measures. Behavioral developmental scores were unaffected. Our results support propranolol as first-line therapy for complicated infantile hemangiomas. <b>What is Known:</b> •Sleep disorders are frequently reported in infants with infantile hemangiomas treated with propranolol and often lead to treatment discontinuation. • Investigations of the sleep pattern in this patient group using objective measures are lacking. <b>What is New:</b> • The sleep pattern of propranolol-treated infants is assessed using actigraphy and a 24-h sleep diary and compared to healthy, untreated controls. • Propranolol leads to a decreased sleep efficiency at night and an increased demand of daytime sleep, yet effects are mild overall.

scholarly journals Sleep behavior of infants with infantile hemangioma treated with propranolol—a cohort study

2021 ◽  
Author(s):  
Martin Theiler ◽  
Nicole Knöpfel ◽  
Susanne von der Heydt ◽  
Agnes Schwieger-Briel ◽  
Isabelle Luchsinger ◽  
...  
Keyword(s):  
Cohort Study ◽  
Sleep Quality ◽  
Outcome Measures ◽  
Negative Impact ◽  
Behavioral Development ◽  
Sleep Efficiency ◽  
Sleep Pattern ◽  
Control Group ◽  
Infant Sleep ◽  
Sleep Behavior

AbstractSleep problems are frequently reported in infants treated with propranolol for infantile hemangiomas, possibly serving as a marker for a negative impact on central nervous system function. In this cohort study, we objectively investigate the sleep behavior of infants with infantile hemangiomas on propranolol compared to a healthy, untreated control group. Sleep of propranolol-treated infants and controls was investigated using ankle actigraphy and a 24-h diary for 7–10 days at ages 3 and 6 months. The main outcome measures were the Number of Nighttime Awakenings and Sleep Efficiency. The main secondary outcome measures included 24-hour Total Sleep, daytime sleep behavior, and parent-rated infant sleep quality and behavioral development based on the Brief Infant Sleep Questionnaire (BISQ) and the age-appropriate Ages-and-Stages Questionnaire (ASQ), respectively. Fifty-four term-born infants were included in each cohort. No group difference in any investigated parameter was seen at age 3 months. At age 6 months, the propranolol group exhibited a decrease in Sleep Efficiency and a trend towards an increased Number of Nighttime Awakenings compared to the control group. Treated infants at 6 months also had shorter daytime waking periods. 24-hour Total Sleep was unaffected by propranolol. No negative impact of propranolol on subjective sleep quality and behavioral development was noted.Conclusion: Propranolol exerts a measurable yet mild impact on objectively assessed infants’ sleep measures. Behavioral developmental scores were unaffected. Our results support propranolol as first-line therapy for complicated infantile hemangiomas. What is Known:• Sleep disorders are frequently reported in infants with infantile hemangiomas treated with propranolol and often lead to treatment discontinuation.• Investigations of the sleep pattern in this patient group using objective measures are lacking. What is New:• The sleep pattern of propranolol-treated infants is assessed using actigraphy and a 24-h sleep diary and compared to healthy, untreated controls.• Propranolol leads to a decreased sleep efficiency at night and an increased demand of daytime sleep, yet effects are mild overall.

Perceived Partner Responsiveness Predicts Better Sleep Quality Through Lower Anxiety

2016 ◽  
Vol 8 (1) ◽  
pp. 83-92 ◽  
Author(s):  
Emre Selcuk ◽  
Sarah C. E. Stanton ◽  
Richard B. Slatcher ◽  
Anthony D. Ong
Keyword(s):  
Sleep Quality ◽  
Sleep Problems ◽  
Sleep Efficiency ◽  
Anxiety And Depression ◽  
Depression Symptoms ◽  
Sleep Study ◽  
Sleep Behavior ◽  
Subjective Sleep ◽  
Perceived Partner Responsiveness ◽  
Partner Responsiveness

The present study investigated whether perceived partner responsiveness—the extent to which individuals feel cared for, understood, and validated by their partner—predicted subjective sleep problems and objective (actigraph-based) sleep efficiency through lower anxiety and depression symptoms. A life span sample of 698 married or cohabiting adults (35–86 years old) completed measures of perceived partner responsiveness and subjective sleep problems. A subset of the sample ( N = 219) completed a weeklong sleep study where actigraph-based measures of sleep efficiency were obtained. Perceived partner responsiveness predicted lower self-reported global sleep problems through lower anxiety and depression and greater actigraph-assessed sleep efficiency through lower anxiety. All indirect associations held after controlling for emotional support provision to the partner, agreeableness, and demographic and health covariates known to affect sleep quality. These findings are among the first to demonstrate how perceived partner responsiveness, a core aspect of romantic relationships, is linked to sleep behavior.

scholarly journals Improvement of sleep patterns and serum melatonin levels in children with autism spectrum disorders after consumption of beta-1,3/1,6-glucan in a pilot clinical study

2021 ◽  
Author(s):  
Kadalraja Raghavan ◽  
Vidyasagar Devaprasad Dedeepiya ◽  
Ramesh Shankar Kandaswamy ◽  
Mangaleswaran Balamurugan ◽  
Nobunao Ikewaki ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Sleep Quality ◽  
Conventional Therapy ◽  
Autism Spectrum ◽  
Sleep Pattern ◽  
Control Group ◽  
Melatonin Level ◽  
Poor Sleep ◽  
Sleep Patterns ◽  
Spectrum Disorders

Abstract Study objectives: Poor sleep quality is a major problem that patients with autism spectrum disorders (ASD) face, which is attributed to their low melatonin levels. Melatonin supplementation is recommended, but its effectiveness is varied. Beta-glucans have previously been reported to improve melatonin levels in animal studies. Therefore, we examined the effectiveness of Aureobasidium pullulans (Nichi Glucan), a species of black yeast that contains beta-1,3/1,6-glucan, in a pilot study of children with ASD. Methods Thirteen children (age = 2.5 to 13 years) with ASD were recruited into the study. The control group consisted of four patients (Gr. 1), while nine patients were in the treatment group (Gr. 2). Gr. 2 received 1 g of Nichi Glucan along with conventional therapy, whereas Gr. 1 underwent conventional therapy alone for 90 days. The serum melatonin levels and sleep patterns, assessed using a subjective questionnaire, were evaluated before and after treatment. Results In Gr. 2, the average serum melatonin level increased from 238.85 ng/dl pre-intervention to 394.72 ng/dl post-intervention. Eight out of nine subjects (88%) in Gr. 2 group showed and improvement in their sleep pattern and quality, while this improvement was not observed in the control group. Conclusions Our study is the first in the literature to report that consumption of Nichi Glucan for 90 days showed visible improvement in sleep quality, sleep pattern, and serum melatonin levels. A larger multicentre study is warranted to validate our findings.

scholarly journals Sleep quality, REM sleep behavior disorder and daytime sleepiness in adults with and without Parkinson's

2021 ◽  
Vol 26 (2) ◽  
pp. 20-25
Author(s):  
Andrea Díaz Pacheco ◽  
Jesús Moo Estrella
Keyword(s):  
Parkinson’S Disease ◽  
Sleep Quality ◽  
Rem Sleep ◽  
Daytime Sleepiness ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Control Group ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Sleep Behavior

In Parkinson's disease (PD), poor sleep quality and sleep disorders are central part of the non-motor symptoms. The aim was to compare sleep quality (SQ), REM sleep behavior disorder (RBD) and excessive daytime sleepiness (EDS) among adults with and without Parkinson's disease (PD). A second objective was to know the relationship of SQ and RBD with EDS in patients with PD. Method. sixty adults (38 % women,  mean age 66.7 ± 8.11 years), 50 % with PD diagnosis and 50 % healthy controls, Instruments: Epworth Sleepiness Scale, Sleep Quality Pittsburgh Index and REM Behavioral Disorder Sleep Questionnaire, which was designed for this study. Results. Differences were found in SQ (PD = 9.90 ±4.47 vs Control group = 7.23 ±4.71, t = 2.25, p = .028), and the percentage of cases with symptoms of RBD (PD = 30%, control group = 6.7%, ji2 = 5.455, p = .020). No differences were found in EDS (PD = 7.43 ± 5.46 vs Control group = 6.50 ± 5.28, t = .673, p = .504). According to the linear regression analysis, the increase in EDS was not associated with SQ, EDS was only associated with RBD. Conclusion, the PD group presents a poor sleep quality and a higher prevalence of RBD symptoms. EDS did not differ between adults with and without PD. However, RBD was associated with an increase in EDS in the PD group.

scholarly journals The effects of online group mindfulness training on stress and sleep quality during the COVID-19 pandemic in Singapore: a retrospective equivalence trial (Preprint)

2020 ◽  
Author(s):  
Julian Lim ◽  
Zaven Leow ◽  
Jason Ong ◽  
Ly-Shan Pang ◽  
Eric Lim
Keyword(s):  
Sleep Quality ◽  
Psychological Health ◽  
Negative Impact ◽  
Daily Practice ◽  
Mindfulness Training ◽  
Analysis Of Covariance ◽  
Control Group ◽  
Present Moment ◽  
Equivalence Trial ◽  
Mental Wellness

BACKGROUND The COVID-19 pandemic has had a negative impact on psychological health. Mindfulness training, which helps individuals attend to the present moment with a non-judgmental attitude, improves sleep and reduces stress in regular times, and may be relevant in mitigating harmful health consequences during acute crises. However, restrictions may necessitate this training being delivered online, rather than in in-person group settings. OBJECTIVE The objective of our study was to establish equivalence of mindfulness interventions delivered via videoconferencing during the COVID-19 pandemic with similar programs delivered in person. METHODS Data from an ongoing study were used for this retrospective equivalence trial. Participants were recruited (with no exclusion criteria) from enrollees in mindfulness courses at a local charity organization promoting mental wellness. Three groups were created, two that received their training during the period of the COVID-19 pandemic (in-person (N = 36) and videoconferencing (N = 38)), and a second control group of participants tested before the pandemic (N = 86). Primary outcomes were self-reported stress and sleep quality. Baseline levels, and changes in these variables due to mindfulness training were compared among the groups using analysis of covariance and two one-sided t-tests. RESULTS Perceived stress and sleep quality did not differ significantly between groups at baseline. Mindfulness training significantly reduced stress in all three groups, and this effect was statistically equivalent for videoconferencing compared to in-person training. Sleep quality improved significantly in the pre-pandemic group, but in neither of the groups during the pandemic. Participants reported shorter times to initiate sleep following mindfulness training pre-pandemic, but not during the pandemic. Course attendance was high and equivalent across the online and comparison groups, and participants engaged in marginally more daily practice in the online condition. CONCLUSIONS Online mindfulness training via videoconferencing may be a useful intervention for stress reduction but not sleep improvement during times when traditional in-person training is not feasible. CLINICALTRIAL The aims for this study were retrospectively registered as part of an ongoing protocol at ClinicalTrials.gov with registration number NCT04417153

scholarly journals 0231 Sleep Behaviors of Female Collegiate Athletes

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A89-A89
Author(s):  
D J Frisco ◽  
J A Goodrich ◽  
M Holliday ◽  
K A Kroeker ◽  
C Whiting ◽  
...  
Keyword(s):  
Sleep Duration ◽  
Collegiate Athletes ◽  
Sleep Efficiency ◽  
Control Group ◽  
Full Time ◽  
Student Athlete ◽  
Sleep Behavior ◽  
Wrist Actigraphy ◽  
Female Collegiate Athletes ◽  
Physiologic Function

Abstract Introduction Sleep is critical to cognitive and physiologic function. It is likely being a female collegiate student athlete places unique demands upon sleep behavior. Therefore, we aimed to study the sleep behavior of female collegiate athletes versus a female collegiate control group. Methods Full time female students from the University of Colorado Boulder (Altitude = 1,624 m) were recruited from NCAA Division I athletic teams: Cross Country (XC, n=10), Lacrosse (LAX, n =17), Soccer (SOC, n=15), Golf (GOLF, n=6), Tennis (TENN, n=9). 31 female full-time students were recruited as Controls (CONT). Sleep was monitored with wrist actigraphy (Spectrum Actiwatch, Phillips) for a minimum of one week. Subjects were instructed to wear actigraphs at all times except during competition. Outcome variables included nightly sleep duration, total 24h sleep duration, sleep efficiency, sleep midpoint, social jet lag (SJL) and nap duration/frequency. Results On weekdays, XC, LAX and SOC had greater nightly sleep durations ~8.5h compared to TENN, GOLF and CONT (p&lt;0.05). Relative to other groups, XC had the earliest sleep midpoint (3:34 AM ± 1:20 vs. 3:53 AM ± 1:15) while SOC and LAX had the lowest sleep efficiency (~87.3 ± 3.2% vs. ~89.6 ± 3.4%) (all p&lt;0.05). There was significant SJL among CONT, LAX and SOC (difference of sleep midpoints on weekdays and weekends; p&lt;0.05). While nightly sleep duration varied significantly between different groups, there were no significant differences in total daily sleep duration when naps are included. A greater percentage of CONT (87 %) napped compared to athletes (64.2 %) (p&lt;0.05); napping duration/frequency of naps per week were not different between groups. Conclusion Variations in sleep behavior exists between collegiate student athletes based upon varsity sport with some sports being similar to controls and others being significantly different. Additional research is needed to determine the significance of these findings to academic and athletic performance. Support PAC-12 Student-Athlete Health and Wellbeing Initiative, Grant #1554240

scholarly journals Restless Leg Syndrome and Sleep Quality in Lumbar Radiculopathy Patients

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Ersoy Kocabicak ◽  
Murat Terzi ◽  
Kursad Akpinar ◽  
Kemal Paksoy ◽  
Ibrahim Cebeci ◽  
...  
Keyword(s):  
Conservative Treatment ◽  
Sleep Quality ◽  
Behavior Disorder ◽  
Control Group ◽  
Lumbar Radiculopathy ◽  
Rapid Eye Movement Sleep ◽  
Restless Leg Syndrome ◽  
Sleep Behavior ◽  
Fatigue Severity ◽  
Number Of Individuals

Background. To investigate the frequency of restless leg syndrome (RLS), sleep quality impairment, depression, fatigue, and sleep behavior disorder and to determine the effects of surgery on these parameters in radiculopathy patients resistant to conservative treatment.Methods. The present study included 66 lumbar radiculopathy patients, who were resistant to conservative treatment and had indication of surgery. Five different questionnaires were performed to assess depression (the Beck Depression Inventory (BDI)), sleep quality (the Pittsburgh Sleep Quality Index (PSQI)), fatigue (the Fatigue Severity Scale (FSS)), and presence of RLS and rapid eye movement sleep behavior disorder (RBD). The same questionnaires were also performed on a control group(n=61).Results. Of the radiculopathy patients, 68.1% had RLS and 92.4% had fatigue. Of the controls, 16.4% had RLS and 59% had fatigue. RBD was present in 8 (12.1%) patients and 3 (4.9%) controls. The PSQI revealed that sleep quality was impaired in 46 (69.7%) patients and 35 (57.4%) controls(P>0.05). The number of individuals having substantial depression according to the BDI was significantly higher in the patients than in the controls.Conclusions. There was a significant increase in the frequency of RLS, which was significantly decreased in the postoperative period in the radiculopathy patients.

scholarly journals Educational Model for Overcoming Stunting Toddlers with Bio Acupressure Massage Using Pure Coconut Oil

2021 ◽  
Vol 54 (2) ◽  
pp. 390
Author(s):  
Nyoman Ribek ◽  
I Gusti Ketut Gede Ngurah ◽  
Ketut Labir ◽  
Ketut Wardani
Keyword(s):  
Sleep Quality ◽  
Negative Impact ◽  
Coconut Oil ◽  
The Body ◽  
Control Group ◽  
P Value ◽  
Educational Model ◽  
Educational Models ◽  
Significant Difference ◽  
Before And After

Educational models to overcome stunting are needed because stunting has a negative impact on the health and function of the body as well as increasing child morbidity. The prevalence of stunting under five in Indonesia in 2019 was 27.67%, in Bali 21.9% and Karangasem 26.23% above WHO 20%. This data is the reason for conducting research in 2020. The aim is to find out whether the educational model of bio acupressure massage using virgin coconut oil can increase appetite, sleep quality and immune power so that stunting toddlers increase height. The research method is quasi-experimental; the research design is nonequivalent control group design. The sample is 50 people with purposive sampling technique. The analysis before and after treatment was carried out by paired sample t-test, the results were that all variables had significant differences (P value> 0.05). Variable differences between groups using t-two independent test with an alpha of 0.05 resulted in a significant difference in appetite (P value = 0.01) and a significant difference in height (p value = 0.020). There was no significant difference between sleep quality and endurance (P value > 0.05). It was concluded that there was a significant difference before and after education on stunting, while between the bio acupressure and conventional groups there was a significant difference in the variables of appetite and height. It is recommended that in overcoming stunting, bio acupressure massage education is the right education.

scholarly journals Pengaruh Slow Stroke Back Massage Terhadap Kualitas Tidur Ibu Post Sectio Caesarea di RS. Bhayangkara Bengkulu

2020 ◽  
Vol 2 (1) ◽  
pp. 41-50
Author(s):  
Anninah Anninah ◽  
Asmawati Asmawati ◽  
Sariman Pardosi
Keyword(s):  
Sleep Quality ◽  
Negative Impact ◽  
Intervention Group ◽  
Sampling Technique ◽  
Sectio Caesarea ◽  
Control Group ◽  
Control Group Design ◽  
And Control ◽  
Back Massage

Mother with sectio caesarea needs sleep for recovery and treatment. Mother with sleep disorders have a negative impact on quality of maternal health. Purpose of this research to determined effect of slow stroke back massage on quality of post-sectio caesarea mother's sleep. This study used quasi experimental with pre-test and post-test with control group design. Samples were taken mother with sectio caesarea at RS. Bhayangkara Bengkulu with 2 groups  of consecutive sampling technique and each group obtain 15 respondents. The analysis used independent sample t-test at α <5%. The result of  intervention group and control group before being given a slow stroke back massage were each average of sleep quality scores 10.27 and 8.00, meanwhile the result of intervention group and control group after being given a slow stroke back massage were each average of sleep quality scores 8.80 and 7.60. The  slow stroke back massage teraphy need to restore the quality of post-sectio caesarea mother's sleep in RS. Bhayangkara Bengkulu.

Sleep pattern in an experimental model of chronic kidney disease

2010 ◽  
Vol 299 (6) ◽  
pp. F1379-F1388 ◽  
Author(s):  
Camila Hirotsu ◽  
Sergio Tufik ◽  
Cassia Toledo Bergamaschi ◽  
Neuli Maria Tenorio ◽  
Paula Araujo ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Disease Progression ◽  
Sleep Problems ◽  
Sleep Efficiency ◽  
Sleep Pattern ◽  
Control Group ◽  
Initial Increase ◽  
High Prevalence ◽  
Hormonal Fluctuations

The prevalence of sleep disorders is significantly elevated in chronic kidney disease (CKD) patients. Numerous factors likely contribute to the high prevalence of sleep problems in uremic patients. The objective of this study was to evaluate the long-term sleep pattern changes in uremic rats during disease progression. Sleep recordings of the rats were monitored during light and dark periods that lasted 12 h each. These recordings were performed on days 7, 30, 60, and 90 after CKD induction. Cardiovascular, hormonal, and biochemical changes were evaluated at these same time points in control and uremic rats. CKD progression was reflected by the presence of hypertension and progressive increases in urea, creatinine, and cholesterol levels. We also observed hormonal fluctuations of corticosterone and ACTH, which indicated a potential alteration in the hypothalamic-pituitary-adrenal axis in diseased rats. In addition, rats with CKD demonstrated fragmented sleep with a greater number of arousals and decreased sleep efficiency in the light period during disease progression. In the dark period, there was an initial increase in sleep efficiency in CKD rats, but after 90 days of CKD, these animals slept less compared with the control group. Collectively, these metabolic and cardiovascular changes were associated with the persistent alterations in sleep architecture observed in CKD rats.

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