scholarly journals Severe Acute Respiratory Syndrome Corona Virus-2 Infection in a Pediatric Kidney Transplant Recipient: A Case Report from India

2021 ◽  
pp. 367-373
Author(s):  
Ravi Raju Tatapudi ◽  
Venkateswara Rao Kopparti ◽  
Anusha Poosapati ◽  
Srinivas Metta ◽  
Vedita Palli ◽  
...  

COVID-19 pandemic affected millions of people across India. COVID-19 cases are fewer in children with less severity and better outcomes than in adults. However, a small proportion develop severe illness and succumb to the disease. Clinical manifestations and optimal management of COVID-19 in immunocompromised children are not clearly known. Remdesivir was shown to be efficient in reducing the recovery time in COVID-19 patients requiring supplemental oxygen. Remdesivir is approved for use in children with severe COVID-19, but there are no guidelines in patients with risk factors like recent solid organ transplantation. We report a case of a 10-year-old kidney transplant recipient (KTR) infected with severe acute respiratory syndrome corona virus-2, 2.5 months after the transplantation. Unlike most children, he presented with high fever, cough, and vomiting. His inflammatory markers were elevated. In this case report, we discussed management and clinical outcomes of this patient. In view of recent kidney transplantation and the severity of infection with emergent oxygen requirement, we gave him remdesivir. We continued prednisolone and tacrolimus and stopped mycophenolate. He recovered completely in 7 days. We feel that severely immunosuppressed KTR children with COVID-19 will benefit with remdesivir administration. Monitoring tacrolimus trough levels is essential for maintaining adequate immunosuppression.

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Shree Kumar ◽  
Talal Alfaadhel ◽  
Meteb M. AlBugami

Infections remain a dreadful complication after solid organ transplantation. Almost all microorganisms could cause this complication, including unusual ones. We report a 73-year-old patient, with a history of kidney transplant for 38 years on minimum immunosuppression, who presented with high-grade fever and gastrointestinal symptoms.Klebsiella ozaenaewas isolated from blood cultures. She had a prompt response to antibiotics and recovered completely in a short period. Subsequent evaluation of her nasal cavity and sinuses did not show any abnormalities.Klebsiella ozaenaeis primarily a colonizer of the oral and nasopharyngeal mucosa, which does not usually cause severe infections. Only 12 cases ofKlebsiella ozaenaebacteremia have been reported, none of them in the context of solid organ transplant recipient.


2020 ◽  
Vol 8 ◽  
pp. 2050313X2095303
Author(s):  
Camille Pennou ◽  
Eileen Javidi ◽  
Julie Lecours ◽  
Annie Bélisle ◽  
Sandra Davar

Trichodysplasia spinulosa is a rare cutaneous disease caused by the trichodysplasia spinulosa–associated polyomavirus. It occurs more frequently in immunocompromised patients, particularly in solid organ transplants. A few successful treatments have been described in the literature. In our report, we present a biopsy-proven trichodysplasia spinulosa case in a kidney transplant recipient who rapidly responded to a reduction of his immunosuppressive therapy.


2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Oscar Xavier Hernández-Rodríguez ◽  
Octavio Alvarez-Torres ◽  
Norma Ofelia Uribe-Uribe

Microorganisms of the microsporidia group are obligated intracellular protozoa that belong to the phylum Microspora; currently they are considered to be related or belong to the fungi reign. It is considered an opportunistic infection in humans, and 14 species belonging to 8 different genera have been described. Immunocompromized patients such as those infected with human immunodeficiency virus (HIV), also HIV serum-negative asymptomatic patients, with poor hygienic conditions, and recipients of bone marrow or solid organ transplantation are susceptible to develop deinfection. Sixtytransplantedpatients with renal microsporidia infection have been reported worldwide. The aim of this paper is to inform about the 2nd case of kidney transplant and microsporidia infection documented in Mexico.


2021 ◽  
pp. 101196
Author(s):  
Torki M AlOtaibi ◽  
Osama A Gheith ◽  
Khaled Alobaid ◽  
Prasad Nair ◽  
Sohair M Zein Eldein ◽  
...  

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