Abstract 32: Is the Seattle Angina Questionnaire suitable for Chinese patients?

Author(s):  
Hui Y Zhang ◽  
Li Yu ◽  
Mei J Lju ◽  
Chang H Yu ◽  
Zhi H Chen ◽  
...  

Background: The Seattle Angina Questionnaire (SAQ) has been widely used in China since it was introduced in 1996. However, the validity and reliability of the translated SAQ has never been assessed in published papers. Even worse, when we use the translated SAQ in clinical studies, we found some patients have difficulty upon understanding some items due to the translation and cultural inadaptation. In this study, we are going to find out if the SAQ is suitable for Chinese patients. Methods: Step one: to assess the psychometric properties of SAQ, 1787 angina patients’ data of our previous cross-section study was used. Exploratory Factor Analysis (EFA) was used to evaluate the construct validity, and internal consistency (Cronbach’s alpha coefficient) was used to evaluate the reliability, and t-test was used to discriminate patients with different Canadian Cardiovascular Society Classification (CCSC) levels. Step two: to find out which item is unsuitable, semi-structured individual patient interview was used. Patients were asked to complete a copy of SAQ first, and then were asked did they encounter difficulties on understanding the items and why. Results: Step one: Cronbach’s alpha coefficient was 0.885, but 0.605 for the quality of life domain. EFA showed 4 factors and couldn’t match the original five domains. More than 50% of patients give the same answer “mostly satisfied” to item 6-8 about treatment satisfaction, and these items can’t detect the differences among patients with different CCSC levels. Item 5 “bothersome of taking pills” is highly correlated with Quality of life domain other than the treatment satisfaction domain it is intended to measure. The correlation between item 6 and 8 is 0.816, which shows a redundancy. The reliability and validity of the translated SAQ is not satisfied. Step two: 92 out of 112 invited patients participated in the interview, 39 (42.39%) couldn’t understand item 10, and 7 (7.61%) of item 6. As to item 10, “feeling of the current angina if long-lasting”, patients were confused of the answer “level of satisfaction”, which result a low internal consistency of Qol. As to item 6, “everything is done for treatment”, 75 (81.52%) patients thought it’s the same meaning with item 8 “satisfaction with current treatment.” Maybe influenced by Confucian, patients chose “satisfaction” even their angina getting worse. Among the 1787 patients, 131 (7.33%) patients took nitros when angina attacked; however, 234(13.09%) patients took Chinese herbal medicine. So they couldn’t answer item 4 “frequency of nitros taken for angina” correctly. Conclusions: The currently used SAQ is unsuitable for Chinese patients. It doesn’t completely capture the characteristics and conditions of Chinese patients. Further study is needed to adapt both, the translation and culture of the SAQ.

2021 ◽  
Vol 10 (10) ◽  
pp. 2081
Author(s):  
Edyta Kinel ◽  
Krzysztof Korbel ◽  
Piotr Janusz ◽  
Mateusz Kozinoga ◽  
Dariusz Czaprowski ◽  
...  

The study aimed to carry on the process of the cultural adaptation of the Italian Spine Youth Quality of Life Questionnaire (ISYQOL) into Polish (ISYQOL-PL). The a priori hypothesis was: the ISYQOL-PL questionnaire is reliable and appropriate for adolescents with a spinal deformity. Fifty-six adolescents (mean age 13.8 ± 1.9) with idiopathic scoliosis (AIS) with a mean Cobb angle 29.1 (±9.7) and two with Scheuermann juvenile kyphosis (SJK) with a kyphosis angle 67.5 (±17.7) degrees were enrolled. All patients had been wearing a corrective TLSO brace for an average duration of 2.3 (±1.8) years. The Institutional Review Board approved the study. The cross-cultural adaptation of the ISYQOL-PL was performed following the guidelines set up by the International Quality of Life Assessment Project. The reliability was assessed using internal consistency (the Cronbach’s alpha coefficient) and test–retest reliability (intraclass correlation coefficient ICC2.1, CI = 95%); moreover, floor and ceiling effects were calculated. The internal consistency was satisfactory (Cronbach’s alpha coefficient 0.8). The test–retest revealed high reliability with the value of ICC2.1 for the entire group 0.90, CI (0.84 to 0.94). There was neither floor nor ceiling effect for the ISYQOL-PL overall score. The ISYQOL-PL is reliable and can be used in adolescents with spinal deformity.


2021 ◽  
Author(s):  
Amer Almarabheh ◽  
Manal Al Ghamdi ◽  
Abdulla Elbarbary ◽  
Ahmed Alqashar ◽  
Faisal alserdieh ◽  
...  

Abstract Background Limited attention is devoted to the improvement of the quality of life of patients suffering from the negative consequences of Sickle cell disease (SCD). Our study focuses on the evaluation of the performance of the WHOQOL-BREF as a tool to measure the quality of life of SCD Patients in Bahrain. Methods We conducted a cross-sectional study that enrolled 273 SCD patients selected using a simple random sampling technique from primary health-care centers in Bahrain in 2019. A designed questionnaire including the WHOQOL-BREF was filled by the patients during face-to-face interviews in the health centers. The reliability of the WHOQOL-BREF was assessed by standardized Cronbach’s alpha coefficient, and the validity was measured by convergent validity, principal component analysis and confirmatory factor analysis. Results The WHOQOL-BREF had good internal consistency as Cronbach’s alpha coefficient for the overall scale was 0.91. The convergent validity results indicated that the correlation coefficients values for all scale domains are significantly correlated at α < 0.01. Confirmatory factor analysis found that the four-domain structure produced a robust fit to the data. Conclusions The WHOQOL-BREF tool has high internal consistency and validity in assessing the quality of life of Sickle Disease patients in Bahrain.


Author(s):  
Concepción Soto-Vidal ◽  
Soraya Pacheco-da-Costa ◽  
Victoria Calvo-Fuente ◽  
Sara Fernández-Guinea ◽  
Carlos González-Alted ◽  
...  

Background: Stroke causes a wide variety of clinical manifestations that may have a negative impact on quality of life. Therefore, it is very important to use specific instruments for measuring quality of life in individuals who suffered a stroke. The aim of this study was to develop a psychometrically validated Spanish version of the Newcastle stroke-specific quality of life measure (NEWSQOL). Methods: A psychometric validation of the Spanish version of the NEWSQOL questionnaire was carried out in 159 patients. The reliability (intraclass correlation coefficient and Cronbach’s alpha coefficient), validity (factorial analysis and Spearman’s coefficient), feasibility (response rate), and the ceiling and floor effects were calculated. Results: Internal consistency showed that Cronbach’s alpha coefficient was 0.93. The test–retest reliability was high or excellent for all domains (range 0.71–0.97 p < 0.001). The response rate of the questionnaire was 100% and the average administration time was 20.5 (±7.2) min. No ceiling effect was detected and two domains (pain and vision) may have a significant potential for floor effect. Construct validity showed that all the variables are important enough to keep them all in the questionnaire. Concerning convergent construct validity, a high correlation was found with the Nottingham Health Profile, the Barthel Index, and the Modified Rankin Scale. Conclusion: The Spanish version of the NEWSQOL questionnaire is reliable, valid, and feasible to evaluate quality of life in the Spanish population.


Author(s):  
Milan Nešić ◽  
Romana Romanov ◽  
Tatjana Jezdimirović ◽  
Josip Lepeš ◽  
Slobodan Andrašić

In order to determine the metric characteristics of the scale intended for the assessment of the quality of life of persons with lumbar syndrome (PQL-LS) on a sample of 202 subjects (M = 93; F = 109), three procedures for checking its metric characteristics were applied: factor analysis (Principal Components Analysis) with the Direct Oblimin method, in order to identify the latent structure of the perception of the quality of life of the respondents; Scale Reliability Analysis based on Cronbach’s alpha coefficient; and a validation check based on the coefficient of internal correlation of the scale (Spearman’s correlation of rank - rho). The results show that the scale has good metric characteristics and that it has a multi-item character (twenty-seven indicators). The internal accordance of the scale is in the high reference range of the Cronbach’s alpha coefficient (0.947). The values of correlation coefficient of subscale scores: physical health, mental health, social relations and environment show a high degree of correlation with the overall mean value of the entire scale, which confirms the validity of the analyzed domains (subscale) and the scale as a whole (at the level of significance r <0.001). All 27 variables yielded the corresponding weight of the single extracted component (KMO = 0.901; Sig. = 0.000), which determined that the scale had adequate validity. Based on the identified good metric characteristics, this scale can be recommended for use as a unique/autonomous multi-item scale designed to assess the quality of life of adults with lumbar syndrome.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Huiling Liew ◽  
Torquil Watt ◽  
Luo Nan ◽  
Alvin W. K. Tan ◽  
Yiong Huak Chan ◽  
...  

Abstract Background Graves’ disease is the most common cause of hyperthyroidism. It results in accelerated tissue metabolism with multi-organ involvement ranging from cardiovascular to neuropsychological function. This results in a negative impact on the quality of life (QOL) of the individual patient. We aim to evaluate the psychometric properties of ThyPRO, a Thyroid-related Patient Reported Outcome questionnaire, and validate its use in our multi-ethnic Asian patients with Graves’ hyperthyroidism. Methods Forty-seven consecutive Graves’ hyperthyroidism patients answered the ThyPRO questionnaire at baseline and at 4 months after treatment initiation. Data were recorded for thyroid related symptoms and signs, thyroid function tests and thyroid volume. We analyzed the internal consistency using Cronbach’s alpha, construct validity by evaluating relationship between clinical variables and ThyPRO scales, ceiling and floor effects, and responsiveness of ThyPRO to treatment based on Cohen’s effect size. Results Correlations between individual scale scores and free thyroxine concentrations were moderate and statistically significant: 0.21–0.64 (p <  0.05). There was high internal consistency between the items in this instrument, Cronbach’s alpha > 0.7 for all scales. ThyPRO was responsive to the changes in QOL after treatment (Effect Size: 0.20–0.77) in 9 of the 14 scales including the hyperthyroid symptoms and psychosocial scales (Tiredness, Cognitive complaints, Anxiety, Emotional susceptibility, Impact on Social, Daily and Sex life). Conclusion This study provides evidence that ThyPRO has satisfactory measurement properties in hyperthyroid Graves’ disease patients in Singapore population with the potential to complement clinical care.


2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Simone De Sio ◽  
Fabrizio Cedrone ◽  
Donatella Sanità ◽  
Pasquale Ricci ◽  
Paola Corbosiero ◽  
...  

Background. Quality of working life is the result of many factors inherent in the workplace environment, especially in terms of exposure to psychosocial risks. Objectives. The purpose of this study is to assess the quality of life with special attention to gender differences. Methods. The HSE-IT questionnaire and the WHO-5 Well-Being Index were administered to a group of workers (74 males and 33 females). The authors also used Cronbach’s alpha test to assess the internal consistency of both questionnaires and the Mann–Whitney test to evaluate the significance of gender differences in both questionnaires. Results. The HSE-IT highlighted the existence of work-related stress in all the population with a critical perception regarding the domain “Relationships.” Furthermore, gender analysis highlighted the presence of two additional domains in the female population: “Demand” (p = 0,002) and “Support from Managers” (p = 0,287). The WHO-5 highlighted a well-being level below the standard cut-off point with a significant gender difference (p=0.009) for males (18, SD = 6) as compared to females (14, SD = 6,4). Cronbach’s alpha values indicated a high level of internal consistency for both of our scales. Conclusions. The risk assessment of quality of working life should take into due account the individual characteristics of workers, with special attention to gender.


2018 ◽  
Vol 7 ◽  
pp. e1106
Author(s):  
Farnoush Barzegar ◽  
Mohamad Amin Pourhoseingholi ◽  
Mohammad Rostami-Nejad ◽  
Sepideh Gholizadeh ◽  
Mohammad Reza Malekpour ◽  
...  

Background: The assessment of health-related quality of life has become an important primary or secondary outcome measure in clinical and epidemiologic studies. The aim of this study was to validate a Persian version of Celiac Disease Questionnaire (CDQ) for Celiac disease (CD) among Iranian patients. Materials and Methods: The English version of the CDQ adapted to the Persian language by a forward-backward translation by 3 professional bilingual translators (1 medical, 2 nonmedical). The content validity of translated questionnaire were studied by 5 experts who complete the validity form regarding the questionnaire. Then in a pilot study, translated CDQ completed by 81 CD patients who referred to Taleghani Hospital, Tehran. For assessing the validity and reliability of the questionnaire, confirmatory factor analysis and Cronbach’s alpha coefficient have been done, using Lisrel and SPSS software. Results: Of 81 CD patients entered to this study with mean age of 30.54 years old, 71.6% were female. Also, 56.8% were married and 45.7% were high educated. The mean of CDQ total score was 119.18±34. The calculated Cronbach’s alpha coefficient for CDQ questionnaire was 0.9. Also, for each subgroups the Cronbach’s alpha coefficient were calculated as the following; emotion: 0.92, Social: 0.89, Worries: 0.73, Gastrointestinal: 0.78. Confirmatory factor analysis indicated that all questions could be remain in questionnaire respectively. Conclusion: The reliability of the Persian version of CDQ was excellent with Cronbach’s alpha coefficients and Persian version of CDQ retains the psychometric properties of the original instrument and should be useful to assess outcome in studies and clinical trials involving Iranian patients with CD. [GMJ.2018;7:e1106]                            


2022 ◽  
Author(s):  
Mina Danaei ◽  
Leyla Bahadorizadeh ◽  
Afsaneh Dehnad ◽  
Shirin Mohamadzadeh ◽  
Nahid Hashemi-Madani ◽  
...  

Abstract Background Acromegaly is a chronic disease seriously impacting the patients' quality of life. This study aimed to validate the Acromegaly Quality of Life Questionnaire (AcroQoL) for the Persian-speaking population. Methods This cross-sectional study recruited 73 Iranian patients with a confirmed diagnosis of acromegaly. The content validity of the scales was evaluated by an expert panel of eight endocrinologists. Construct validity was assessed by using confirmatory factor analysis. Internal consistency was assessed on the basis of Cronbach’s alpha, and a goodness-of-fit (GoF) index was calculated to display whether the model fitted the data. Results The content validity index (CVI) and content validity ratio (CVR) yielded values of 0.85 and 0.80, respectively. The average variance extracted (AVE) from physical and psychological dimensions was 0.520 and 0.462, respectively, exceeding the minimum criterion of 0.40. Cronbach’s alpha for physical and psychological dimensions equaled 0.868 and 0.866, respectively, indicating the adequate internal consistency of multiple items for each construct. The subscales’ R square and path coefficient were greater than the recommended threshold (physical dimension: 0.778, psychological dimension: 0.873), demonstrating the suitability of this criterion. Finally, the GoF value of 0.29 indicated the model's moderate fit. Conclusions The findings revealed that the Persian version of AcroQoL is of adequate validity and reliability for evaluating the quality of life of Iranian people with acromegaly.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Ali Hasanpour Dehkordi ◽  
Marzieh Aslani ◽  
Abbas Ebadi ◽  
Selman Repišti ◽  
Borhan Moradveisi ◽  
...  

Abstract Introduction As a result of high transmission and mortality rates, the Covid-19 pandemic has led to a worldwide health crisis, isolation, and widespread fear, therefore negatively influencing people’s quality of life (QOL). The goal of the present study was to examine the psychometric properties (validity and reliability) of the Persian version of the COVID-19-Impact on Quality of Life (COV19-QoL) scale. Methods After translating the scale using the forward–backward method, face and content validly was qualitatively assessed. Then the scale was distributed to 488 individuals from the general population via online platforms. Construct validity was assessed using exploratory (EFA) and confirmatory (CFA) factor analysis. In addition, internal consistency was examined using Cronbach’s alpha coefficient and McDonald’s omega, relative stability was assessed using interclass correlation coefficient (ICC), and absolute stability was calculated through examination of standard error of measurement. Results The EFA revealed one factor that explained 55.96% of the total variance of the scale. Internal consistencies of 0.823 and 0.882 were found using Cronbach’s alpha coefficient and McDonald’s omega, respectively. In addition, an ICC of 0.837 (with a two-week interval) was found. Covid-19 had a greater impact on the QOL of healthy participants than that of those with underling conditions (p = 0.004), and also on the QOL of single participants than that of married ones (p = 0.032). Conclusion The Persian version of the COV19-QoL is a valid and reliable instrument that can be used to examine the impact of Covid-19 on QOL.


2021 ◽  
Author(s):  
Mina Danaei ◽  
Leyla Bahadorizadeh ◽  
Afsaneh Dehnad ◽  
Shirin Mohamadzadeh ◽  
Nahid Hashemi-Madani ◽  
...  

Abstract Background: Acromegaly is a chronic disease seriously impacting the patients' quality of life. This study aimed to validate the Acromegaly Quality of Life Questionnaire (AcroQoL) for the Persian-speaking population.Methods: This cross-sectional study recruited 73 Iranian patients with a confirmed diagnosis of acromegaly. The content validity of the scales was evaluated by an expert panel of eight endocrinologists. Construct validity was assessed by using confirmatory factor analysis. Internal consistency was assessed on the basis of Cronbach’s alpha, and a goodness-of-fit (GoF) index was calculated to display whether the model fitted the data.Results: The content validity index (CVI) and content validity ratio (CVR) yielded values of 0.85 and 0.80, respectively. The average variance extracted (AVE) from physical and psychological dimensions was 0.520 and 0.462, respectively, exceeding the minimum criterion of 0.40. Cronbach’s alpha for physical and psychological dimensions equaled 0.868 and 0.866, respectively, indicating the adequate internal consistency of multiple items for each construct. The subscales’ R square and path coefficient were greater than the recommended threshold (physical dimension: 0.778, psychological dimension: 0.873), demonstrating the suitability of this criterion. Finally, the GoF value of 0.29 indicated the model's moderate fit.Conclusions: The findings revealed that the Persian version of AcroQoL is of adequate validity and reliability for evaluating the quality of life of Iranian people with acromegaly.


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