scholarly journals Ajmaline‐Induced Abnormalities in Brugada Syndrome: Evaluation With ECG Imaging

2022 ◽  
Author(s):  
Luigi Pannone ◽  
Cinzia Monaco ◽  
Antonio Sorgente ◽  
Pasquale Vergara ◽  
Paul‐Adrian Calburean ◽  
...  
Keyword(s):  
Brugada Syndrome ◽  
Recovery Time ◽  
Area Under The Curve ◽  
Electrocardiographic Imaging ◽  
Mapping System ◽  
Before And After ◽  
History Of ◽  
Noninvasive Mapping ◽  
The Difference ◽  
The Right

Background The rate of sudden cardiac death (SCD) in Brugada syndrome (BrS) is ≈1%/y. Noninvasive electrocardiographic imaging is a noninvasive mapping system that has a role in assessing BrS depolarization and repolarization abnormalities. This study aimed to analyze electrocardiographic imaging parameters during ajmaline test (AJT). Methods and Results All consecutive epicardial maps of the right ventricle outflow tract (RVOT‐EPI) in BrS with CardioInsight were retrospectively analyzed. (1) RVOT‐EPI activation time (RVOT‐AT); (2) RVOT‐EPI recovery time, and (3) RVOT‐EPI activation‐recovery interval (RVOT‐ARI) were calculated. ∆RVOT‐AT, ∆RVOT‐EPI recovery time, and ∆RVOT‐ARI were defined as the difference in parameters before and after AJT. SCD‐BrS patients were defined as individuals presenting a history of aborted SCD. Thirty‐nine patients with BrS were retrospectively analyzed and 12 patients (30.8%) were SCD‐BrS. After AJT, an increase in both RVOT‐AT [105.9 milliseconds versus 65.8 milliseconds, P <0.001] and RVOT‐EPI recovery time [403.4 milliseconds versus 365.7 milliseconds, P <0.001] was observed. No changes occurred in RVOT‐ARI [297.5 milliseconds versus 299.9 milliseconds, P =0.7]. Before AJT no differences were observed between SCD‐BrS and non SCD‐BrS in RVOT‐AT, RVOT‐EPI recovery time, and RVOT‐ARI ( P =0.9, P =0.91, P =0.86, respectively). Following AJT, SCD‐BrS patients showed higher RVOT‐AT, higher ∆RVOT‐AT, lower RVOT‐ARI, and lower ∆RVOT‐ARI ( P <0.001, P <0.001, P =0.007, P =0.002, respectively). At the univariate logistic regression, predictors of SCD‐BrS were the following: RVOT‐AT after AJT (specificity: 0.74, sensitivity 1.00, area under the curve 0.92); ∆RVOT‐AT (specificity: 0.74, sensitivity 0.92, area under the curve 0.86); RVOT‐ARI after AJT (specificity 0.96, sensitivity 0.58, area under the curve 0.79), and ∆RVOT‐ARI (specificity 0.85, sensitivity 0.67, area under the curve 0.76). Conclusions Noninvasive electrocardiographic imaging can be useful in evaluating the results of AJT in BrS.

scholarly journals Effect of pterygium excision on mean corneal curvature.

2021 ◽  
Vol 28 (04) ◽  
pp. 568-571
Author(s):  
Saira Bano ◽  
Sumaya Khan ◽  
Mahnoor Waqar ◽  
Moniba Iqbal ◽  
Hamza Waqar Bhatti ◽  
...  
Keyword(s):  
P Value ◽  
Corneal Curvature ◽  
Ocular Surgery ◽  
Department Of Ophthalmology ◽  
Before And After ◽  
Quasi Experimental ◽  
History Of ◽  
Induced Astigmatism ◽  
Pterygium Excision ◽  
The Difference

Objective: To determine the difference in mean corneal curvatures before and after pterygium excision. Study Design: Quasi-experimental study. Setting: Department of Ophthalmology, Holy Family Hospital, Rawalpindi. Period: 1st January 2015 to 1st July 2015. Material & Methods: 68 patients aged between 18 to 65 years were included in the study. Patients with history of ocular trauma, ocular surgery, glaucoma, anti-glaucoma treatment, allergy to steroids, pseudo pterygium, recurrent pterygium and presence of corneal abnormalities such as, scarring that might affect the astigmatic value were excluded. All patients underwent comprehensive ophthalmic examination by slit lamp and best corrected visual acuity and keratometric values were noted. Pterygium excision was done by a single surgeon. BCVA and keratometric readings were taken again after 2 weeks of pterygium excision. Results: Mean age was 37.60 ± 11.11 years. Out of these 68 patients, 44 (64.71%) were male and 24 (35.29%) were females. Mean pre-operative corneal curvature was 2.99 ± 0.69D and post-operative corneal curvature was 1.70 ± 0.40D with P-value of <0.0001 which is statistically significant. Conclusion: This study concluded that pterygium excision brings significant change in corneal curvature in patients of pterygium induced astigmatism.

scholarly journals Reorientasi Gerakan Feminisme Islam; Sebuah Upaya Membangun Kesetaraan Perempuan

FIKROTUNA ◽  
2017 ◽  
Vol 3 (1) ◽  
Author(s):  
ABD WARITS
Keyword(s):  
Skin Color ◽  
Social Role ◽  
Human Beings ◽  
Men And Women ◽  
The World ◽  
The Status ◽  
History Of ◽  
The Difference ◽  
The Right ◽  
Arbitrary Action

In the history of women's life, the woman has never cracked from the wild cry of helplessness. Woman always become victim of men’s egoism, marginalized, hurt, unfettered, fooled and never appreciated the presence and role. This situation troubles many intellectual Muslims who have perspective that Islam teaches equality, equality for all human beings in the world. The difference in skin color, race, tribe and nation, as well as gender does not cause them to get the status of the different rights and obligations. The potential and the right to life of every human being and the obligation to serve the Lord Almighty is the same. Indeed, all human beings, as caliph in the world, have the same obligation, namely to prosperity of life in the world. No one is allowed to act arbitrarily, destroying, or hurt among others. They are required to live side by side, united, and harmonious, help each other and respect each other. However, that "demand" never becomes a reality. The differences among human identities become a barrier and the cause of divisions. For them, those who are outside environment, different identities are "others" who rightly do not need them "know". The difference of identity has become a reason to allow "hurt" each other. Several intellectual Muslims who recognize the wrong (discrimination against women), and then they attempt to formulate a movement for women's liberation. All the efforts have been done on the basis of awareness that arbitrary action by any person can never be justified. They also realize, that the backwardness of women are "stumbling block" that will lead to the resignation of a civilization. However, this struggle found a lot of challenges; including the consideration of "insubordination" to conquer the power of men, despite it had done by using many strategies. Starting from the writing of scientific book and countless fiction themed women has been published in order to give awareness of equality between men and women. This paper seeks to reexamine the process of the empowerment struggle to give a brand new concept, so that the struggle of women empowerment is not as insubordination and curiosity process in an attempt to conquer the male. Through approach of literature review and observations on the relationship between men and women, the writer finally concluded that the movement of Islamic feminism is not a movement to seize the power of men, but an attempt to liberate women from oppression so that they get the rights of their social role, giving freedom for women to pursue a career as wide as possible like a man, without forgetting a main duty as a mother: to conceive, give birth and breastfeed their children.

Which Inotropic Drug, Dobutamine or Milrinone, Is Clinically More Effective in the Treatment of Postligation Cardiac Syndrome in Preterm Infants?

2020 ◽  
Author(s):  
Levent Korkmaz ◽  
Ahmet Ozdemir ◽  
Özge Pamukçu ◽  
Tamer Güneş ◽  
Mehmet Adnan Ozturk
Keyword(s):  
Blood Pressure ◽  
Operating Characteristic ◽  
Ductus Arteriosus ◽  
Area Under The Curve ◽  
Therapeutic Effects ◽  
Study Group ◽  
Cardiac Syndrome ◽  
Before And After ◽  
The Difference

Objective This study aimed to detect which of the two main medicines suggested in the treatment of postligation cardiac syndrome (PLCS)—dobutamine or mirinone—possesses a more therapeutic effect. While doing this, clinicians are provided with a broader perspective on the treatment and follow-up of cases. The desire was to increase the treatability and monitor ability of the cases in question and hence their survivability. Study Design A retrospective review of a cohort of infants with PLCS was conducted between March 2012 and December 2018. In the treatment of infants with PLCS, dobutamine (dobutamine study group-DSG) or milrinone (milrinone study group-MSG) was used. The respiration, cardiac, echocardiography, and perfusion parameters of the cases were assessed both before and after ligation. Based on the data obtained, both the effects of the medicines on PLCS and the difference between their therapeutic effects were studied. The accuracy of prognostication was assessed with receiver operating characteristic analyses. Results PLCS was detected in 29 (34.1%) of 85 patent ductus arteriosus ligation cases in total. Of all the PLCS cases, 13 (44.8%) were treated with dobutamine and 16 (55.2%) with milrinone. It was observed that the effects of the medicines on the respiratory system and cardiovascular system manifested in the third and 6th hour, respectively. It was detected that both medicines had more effect on the systolic blood pressure (SBP) (area under the curve [AUC]: 0.997/0.996, p = 0.001/0.002) than on the diastolic blood pressure (AUC: 0.911/0.843, p = 0.032/0.046). Conclusion Dobutamine and milrinone, two primary medicines that can be used in the treatment of cases with PLCS, possess similar therapeutic effects on this pathology. In addition, their postoperative therapeutic effects on the SBP are more in the foreground.

scholarly journals Metode Kerja Berorientasi Ergonomi pada Proses Pengelapan Kaleng Sarden Menurunkan Keluhan Muskuloskeletal dan Kelelahan Pekerja di PT. BMP Negara, Bali

2019 ◽  
Vol 5 (1) ◽  
pp. 16
Author(s):  
Ni Luh Gede Aris Maytadewi Negara ◽  
I Dewa Putu Sutjana ◽  
Luh Made Indah Sri Handari Adiputra
Keyword(s):  
Large Scale ◽  
Test Group ◽  
Total Sample ◽  
Musculoskeletal Complaints ◽  
Fatigue Score ◽  
Before And After ◽  
Post Test ◽  
The Difference ◽  
The Right ◽  
A Company

Industrial activities developed from households to large-scale industries, including the development of industries in the field of canning fish. Worker health is one of the important things in a company, can be achieved by choosing the right work method. This study was conducted to determine whether ergonomic oriented working methods in the process of wiping canned sardines can reduce musculoskeletal complaints and fatigue in workers. The study design was two period cross over pre and post-test group desig). The research was conducted at PT. BMP Negara. It was held in December 2016. Total sample were 18 workers who wiping cans of sardines. The difference in conditions between before and after activities using ergonomic un-oriented working methods and ergonomic oriented working methods are compared and tested statistically. Comparison tests were carried out on scores of musculoskeletal complaints and worker fatigue. The results showed that ergonomic oriented working methods decreased of musculoskeletal complaints 17.82% (p<0.05) and fatigue score of 11.86% (p<0.05). The conclusion of this study is that ergonomic oriented working methods in the process of wiping sardine cans reduce musculoskeletal complaints and work fatigue of workers in PT. BMP Negara.

Teaching the History of Technical Communication: A Lesson with Franklin and Hoover

2003 ◽  
Vol 33 (1) ◽  
pp. 65-81 ◽  
Author(s):  
Jeff Todd
Keyword(s):  
Technical Communication ◽  
English Language ◽  
Industrial Revolution ◽  
Technical Writing ◽  
Benjamin Franklin ◽  
Teaching History ◽  
Before And After ◽  
History Of ◽  
The Difference ◽  
The University

The first part of this article shows that research in the history of technical communication has increased in quantity and sophistication over the last 20 years. Scholarship that describes how to teach with that information, however, has not followed, even though teaching the history of the field is a need recognized by several scholars. The article provides and defends four guidelines as a foundation to study ways to incorporate history into classroom lessons: 1) maintain a continued research interest in teaching history; 2) limit to technical rather than scientific discourse; 3) focus on English-language texts; and 4) focus on American texts, authors, and practices. The second part of the essay works within the guidelines to show a lesson that contrasts technical texts by Benjamin Franklin and Herbert Hoover. The lesson can help students see the difference in technical writing before and after the Industrial Revolution, a difference that mirrors their own transition from the university to the workforce.

Life, Liberty, and Property

1984 ◽  
Vol 1 (2) ◽  
pp. 108-118 ◽  
Author(s):  
David Kelley
Keyword(s):  
Specific Form ◽  
Free Society ◽  
Common Root ◽  
History Of Political Thought ◽  
Basic Difference ◽  
Political Position ◽  
History Of ◽  
The Difference ◽  
The Right ◽  
The Ideal

The words “liberty” and “liberalism” have a common root, reflecting the commitment of the original or classical liberals to a free society. Over the last century, the latter term has come to represent a political position that is willing to sacrifice liberty in the economic realm for the sake of equality and/or collective welfare. As a consequence, those who wish to reaffirm the classical version of liberalism – those who advocate liberty in economic as well as personal and intellectual matters – have invented a new word from the old root; they call themselves libertarians. Both in doctrine and in etymology, then, partisans of this view define themselves by their allegiance to liberty. Yet they spend most of their day-to-day polemical energies defending property rights and the economic system of laissez-faire capitalism that is based upon such rights. Evidently there is a strong link between liberty and property at work here. What is that link?The history of political thought is full of ideas and controversies about precisely this question. My goal here is to raise the question in a specific form, one that I think captures a basic difference in approach between classical liberals and most libertarians today. The difference is not in the substance of the position – it is not a disagreement about how the ideal society would be constituted – but rather in the way the position is to be defended. The key question is: can the right to property be derived from the right to liberty?Of course a property right is a right to kind of freedom.

Extradural spinal angiolipoma associated with bone lysis in a dog

1998 ◽  
Vol 34 (5) ◽  
pp. 373-376 ◽  
Author(s):  
U Reif ◽  
CT Lowrie ◽  
SD Fitzgerald
Keyword(s):  
Computed Tomography ◽  
Spinal Cord ◽  
Bone Remodeling ◽  
Spinal Tumor ◽  
Histological Findings ◽  
History Of ◽  
Bone Lysis ◽  
Left And Right ◽  
The Difference ◽  
The Right

An extradural spinal tumor was diagnosed in a 12-year-old Labrador retriever that was presented with a one-week history of paraparesis. Myelography indicated a deviation of the spinal cord to the right side at the level of the second lumbar (L2) vertebra. The difference in length measuring the left and right sides of the L2 vertebra suggested a fracture of the vertebral body. Severe bone remodeling and an extradural mass were seen on computed tomography (CT). Clinical, radiographical, and histological findings are described and considered homologous to extradural angiolipomas described in the human literature.

scholarly journals Brugada syndrome: Case report

2012 ◽  
Vol 140 (1-2) ◽  
pp. 84-90
Author(s):  
Vesna Bisenic ◽  
Sasa Hinic ◽  
Mirjana Krotin ◽  
Branislav Milovanovic ◽  
Jelena Saric ◽  
...  
Keyword(s):  
Family History ◽  
Sudden Death ◽  
Brugada Syndrome ◽  
Troponin T ◽  
Stable Condition ◽  
St Segment Elevation ◽  
St Segment ◽  
History Of ◽  
The Right

Introduction. Brugada syndrome is an arrhythmogenic disease characterized by coved ST segment elevation and J point elevation of at least 2 mm in at least two of the right precordial ECG leads (V1-3) and ventricular arrhythmias, syncope, and sudden death. Risk stratifications of patients with Brugada electrocardiogram are being strongly debated. Case Outline. A 23-year-old man was admitted to the Coronary Care Unit of the Clinical Centre ?Bezanijska kosa? due to weakness, fatigue and chest discomfort. The patient suffered from fainting and palpitations. There was a family history of paternal sudden death at 36 years. Electrocardiogram showed a coved ST segment elevation of 4 mm in leads V1 and V2, recognised as spontaneous type 1 Brugada pattern. Laboratory investigations revealed normal serum cardiac troponin T and serum potassium, and absence of inflammation signs. Echocardiographic finding was normal, except for a mild enlargement of the right atrium and ventricle. The diagnosis of Brugada syndrome was made by Brugada-type 1 electrocardiogram and the family history of sudden death <45 years. The patient was considered as a high risk, because of pre-syncope and palpitations. He underwent ICD implantation (Medtronic MaximoVR7232Cx) using the standard procedure. After implantation, noninvasive electrophysiology study was done and demonstrated inducible VF that was interrupted with the second 35 J DC shock. The patient was discharged in stable condition with beta-blocker therapy. After a year of pacemaker check-ups, there were no either VT/ VF events or ICD therapy. Conclusion. Clinical presentation is the most important parameter in risk stratification of patients with Brugada electrocardiogram and Brugada syndrome.

scholarly journals Efficacy and Safety of a Novel Mouthpiece for Esophagogastroduodenoscopy: A Multi-Center, Randomized Study

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 538
Author(s):  
Yuichiro Ikebuchi ◽  
Kazuya Matsumoto ◽  
Naoki Ueda ◽  
Taro Yamashita ◽  
Hiroki Kurumi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Past History ◽  
Randomized Study ◽  
Saturation Pulse ◽  
Examination Time ◽  
Before And After ◽  
History Of Endoscopy ◽  
History Of ◽  
Secondary Endpoints ◽  
The Difference

This randomized trial aimed to compare the safety and efficacy of the GAGLESS mouthpiece for esophagogastroduodenoscopy (EGD) with that of the conventional mouthpiece. In all, 90 participants were divided into the GAGLESS mouthpiece and conventional mouthpiece groups. The primary endpoint was the severity of pain using the visual analog scale (VAS), and secondary endpoints were examination time, past history of endoscopy, success of the procedure, systolic (SBP) and diastolic (DBP) blood pressure, oxygen saturation, pulse rate before and after EGD, and adverse events. Endoscopy was completed in all cases, and no complications were observed. VAS, when passing the scope through the pharynx, was 2.5 ± 2.4 and 2.0 ± 1.9 cm (p = 0.24) in the conventional and GAGLESS groups, respectively, and that, throughout the examination, was 2.5 ± 2.4 and 1.7 ± 1.5 cm (p = 0.06), respectively. The difference in blood pressure between the GAGLESS and conventional groups was not significant for SBP (p = 0.08) and significant for DBP (p = 0.03). The post-EGD difference in DBP was significantly lower in the GAGLESS group than in the conventional group. The results indicate that GAGLESS mouthpieces had a lower VAS during endoscopy than the conventional mouthpieces, and the changes in blood pressure were smaller with the GAGLESS mouthpiece.

scholarly journals Recovery time, risk factors, and volumetric analysis in acute mTBI

Neurology ◽  
2018 ◽  
Vol 91 (23 Supplement 1) ◽  
pp. S17.2-S17
Author(s):  
Teena Shetty ◽  
Joseph Nguyen ◽  
Taylor Cogsil ◽  
Apostolos John Tsiouris ◽  
Sumit Niogi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Recovery Time ◽  
Age Groups ◽  
Volumetric Analysis ◽  
Initial Symptom ◽  
Psychiatric History ◽  
History Learning ◽  
Symptom Severity Score ◽  
History Of ◽  
The Right

ObjectiveThis study investigated the influence of demographic factors, the course of recovery, and the utility of investigational MR sequences (specifically volumetry) in mild traumatic brain injury (mTBI) patients.BackgroundMost literature suggests that the majority of mTBI patients achieve recovery within 1 month of injury, or sooner. This may be affected by younger age, female sex, concussion history, learning disability, psychiatric history, or migraines. The role of volumetric analysis in mTBI requires further investigation.MethodsOne hundred eleven patients (15–50 years old) enrolled in the study within 10 days of head injury. Patients completed a maximum of 4 encounters over 3 months, undergoing volumetric structural imaging at each visit. Patients were contacted to determine recovery date.ResultsRecovery date was obtained in 73 patients at HSS. The median days to recovery was 44 days (IQR: 23–88 days). 33% of this population was recovered in 30 days, 63% in 60 days, and >75% in 90 days. Of the subjects who were not recovered by 90 days, the right thalamus volume trended towards a negative correlation with SSS at that time point. Initial symptom severity score (SSS) was significantly correlated with increased days to recovery (p = 0.382, p = 0.001). Average days to recover was longer in patients with diagnosed depression, anxiety, or other psychiatric disorder (121 vs 70 days, p = 0.037). No significant differences in days to recovery were found between age groups, sex, learning disorder, previous concussions, or history of migraines.ConclusionAverage time to recover from mTBI may be longer than previously reported. Acute SSS may be a useful indicator in determining recovery time. Of previously reported risk factors, personal psychiatric history may have the greatest effect on recovery time. Despite being interesting, the volumetric correlations did not survive multiple comparison corrections and may not be the most sensitive variable for mTBI imaging.

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