Molecular Logic Gate Based on DNA Strand Displacement Reaction

2021 ◽  
Vol 16 (6) ◽  
pp. 974-977
Author(s):  
Jingjing Ma

In this paper, I construct an XOR logic gate based on DNA strand displacement reaction, and verify our design through corresponding biochemical experiment. I designed several different DNA strands. Based on two basic DNA strand displacement reaction mechanisms, by adding different input strands and taking the signal of FAM fluorescent group as the output, the XOR logic gate is realized. The result shows that DNA strand displacement technology has important application value in DNA computing, especially in the construction of DNA molecular logic gates.

2016 ◽  
Vol 13 (6) ◽  
pp. 3948-3952 ◽  
Author(s):  
Yanfeng Wang ◽  
Wenwen Zhang ◽  
Xing Li ◽  
Guangzhao Cui

The Analyst ◽  
2014 ◽  
Vol 139 (14) ◽  
pp. 3548-3551 ◽  
Author(s):  
Dmitriy A. Khodakov ◽  
Anastasia S. Khodakova ◽  
Adrian Linacre ◽  
Amanda V. Ellis

Oligonucleotide modified magnetic beads for the selective capture and release of forensically relevant genes for human identification.


RSC Advances ◽  
2016 ◽  
Vol 6 (78) ◽  
pp. 74913-74916 ◽  
Author(s):  
Chenxi Li ◽  
Yixin Li ◽  
Yang Chen ◽  
Ruoyun Lin ◽  
Tian Li ◽  
...  

A one-sided remote toehold design was proposed to provide the fine control over strand-displacement reaction kinetics with simplicity and versatility.


2015 ◽  
Vol 51 (39) ◽  
pp. 8307-8310 ◽  
Author(s):  
Hamid Ramezani ◽  
D. Jed Harrison

The DNA strand displacement reaction (SDR) was successfully combined with a fluoroimmunoassay on silica microparticles to accomplish sequence-specific release,in situsample cleanup, and buffer exchange.


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