Pediatric Single-Sided Deafness: A Review of Prevalence, Radiologic Findings, and Cochlear Implant Candidacy

2021 ◽  
pp. 000348942110195
Author(s):  
Nicholas A. Dewyer ◽  
Sullivan Smith ◽  
Barbara Herrmann ◽  
Katherine L. Reinshagen ◽  
Daniel J. Lee
Keyword(s):  
Cochlear Implant ◽  
Cochlear Implantation ◽  
Pediatric Patients ◽  
Medical Center ◽  
Academic Medical Center ◽  
Cochlear Nerve ◽  
Imaging Characteristics ◽  
Common Etiology ◽  
Single Sided Deafness ◽  
Cochlear Nerve Deficiency

Objective: To characterize the prevalence, imaging characteristics, and cochlear implant candidacy of pediatric patients with single-sided deafness (SSD). Methods: An audiometric database of patients evaluated at a large tertiary academic medical center was retrospectively queried to identify pediatric patients (<18 years old) with SSD, defined as severe to profound sensorineural hearing loss in one ear and normal hearing in the other. Medical records of identified patients were reviewed to characterize the prevalence, etiology, and cochlear implant candidacy of pediatric patients with SSD. Results: We reviewed audiometric data obtained from 1993 to 2018 for 52,878 children at our institution. 191 (0.36%) had the diagnosis of SSD. Cochlear nerve deficiency (either hypoplasia or aplasia) diagnosed on MRI and/or CT was the most common etiology of SSD and was present in 22 of 88 (25%) pediatric SSD patients with available imaging data. 70 of 106 (66%) pediatric SSD patients with available imaging had anatomy amenable to cochlear implantation. Conclusions: Pediatric SSD is a rare condition and the most common etiology based on radiology is cochlear nerve deficiency. High resolution imaging of the temporal bone is essential to determine cochlear nerve morphology prior to consideration of cochlear implantation.

scholarly journals Assessment of cochlear implant candidacy in patients with cochlear nerve deficiency using the P1 CAEP biomarker

2012 ◽  
Vol 13 (1) ◽  
pp. 16-25 ◽  
Author(s):  
Peter Roland ◽  
Kathryn Henion ◽  
Timothy Booth ◽  
Julia Dee Campbell ◽  
Anu Sharma
Keyword(s):  
Cochlear Implant ◽  
Cochlear Nerve ◽  
Cochlear Nerve Deficiency

scholarly journals Rapid development of telehealth capabilities within pediatric patient portal infrastructure for COVID-19 care: barriers, solutions, results

2020 ◽  
Vol 27 (7) ◽  
pp. 1116-1120 ◽  
Author(s):  
Pious D Patel ◽  
Jared Cobb ◽  
Deidre Wright ◽  
Robert W Turer ◽  
Tiffany Jordan ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Medical Center ◽  
Rapid Development ◽  
Academic Medical Center ◽  
Security Policies ◽  
Patient Portal ◽  
Privacy And Security ◽  
Academic Medical ◽  
Adolescent Autonomy ◽  
National Emergency

Abstract The COVID-19 national emergency has led to surging care demand and the need for unprecedented telehealth expansion. Rapid telehealth expansion can be especially complex for pediatric patients. From the experience of a large academic medical center, this report describes a pathway for efficiently increasing capacity of remote pediatric enrollment for telehealth while fulfilling privacy, security, and convenience concerns. The design and implementation of the process took 2 days. Five process requirements were identified: efficient enrollment, remote ability to establish parentage, minimal additional work for application processing, compliance with guidelines for adolescent autonomy, and compliance with institutional privacy and security policies. Weekly enrollment subsequently increased 10-fold for children (age 0–12 years) and 1.2-fold for adolescents (age 13–17 years). Weekly telehealth visits increased 200-fold for children and 90-fold for adolescents. The obstacles and solutions presented in this report can provide guidance to health systems for similar challenges during the COVID-19 response and future disasters.

Cochlear implantation in children with labyrinthine anomalies and cochlear nerve deficiency: Implications for auditory brainstem implantation

2011 ◽  
Vol 121 (9) ◽  
pp. 1979-1988 ◽  
Author(s):  
Craig A. Buchman ◽  
Holly F. B. Teagle ◽  
Patricia A. Roush ◽  
Lisa R. Park ◽  
Debora Hatch ◽  
...  
Keyword(s):  
Cochlear Implantation ◽  
Auditory Brainstem ◽  
Cochlear Nerve ◽  
Cochlear Nerve Deficiency

Cochlear implantation in children with cochlear nerve deficiency: A report of nine cases

2012 ◽  
Vol 76 (8) ◽  
pp. 1188-1195 ◽  
Author(s):  
Zhihua Zhang ◽  
Yun Li ◽  
Lingxiang Hu ◽  
Zhaoyan Wang ◽  
Qi Huang ◽  
...  
Keyword(s):  
Cochlear Implantation ◽  
Cochlear Nerve ◽  
Cochlear Nerve Deficiency

scholarly journals 384. SARS-CoV-2 Surveillance Testing Patterns among Hospitalized Pediatric Patients in a Single Academic Medical Center

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S293-S294
Author(s):  
Areej Bukhari ◽  
Jessica Seidelman ◽  
Becky A Smith ◽  
Sarah S Lewis ◽  
Michael J Smith ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Medical Center ◽  
Academic Medical Center ◽  
Solid Organ ◽  
Cell Transplant ◽  
Infection Rates ◽  
Research Support ◽  
Repeat Testing ◽  
Academic Medical ◽  
Community Infection

Abstract Background Children infected with SARS-CoV-2 often have mild or no symptoms, making symptom screening an ineffective tool for determining isolation precautions. As an infection control measure, universal pre-procedural and admission SARS-CoV-2 testing for pediatric patients was implemented in April and August 2020, respectively. Limited data exist on the utility screening programs in the pediatric population. Methods We performed a retrospective cohort study of pediatric patients (birth to 18 years) admitted to a tertiary care academic medical center from April 2020 to May 2021 that had one or more SARS-CoV-2 point-of-care or polymerase chain reaction tests performed. We describe demographic data, positivity rates and repeat testing trends observed in our cohort. Results A total of 2,579 SARS-CoV-2 tests were performed among 1,027 pediatric inpatients. Of these, 51 tests (2%) from 45 patients (4.3%) resulted positive. Community infection rates ranged from 4.5-60 cases/100,000 persons/day during the study period. Hispanic patients comprised 16% of the total children tested, but were disproportionately overrepresented (40%) among those testing positive (Figure1). Of 654 children with repeated tests, 7 (0.1%) converted to positive from a prior negative result. Median days between repeat tests was 12 (IQR 6-45), not necessarily performed during the same hospital stay. Five of these 7 patients had tests repeated &lt; 3 days from a negative result, of which only 2 had no history of recent infection by testing performed at an outside facility. Pre-procedural tests accounted for 35% of repeat testing, of which 0.9% were positive. Repeated tests were most frequently ordered for patients in hematology/oncology (35%) and solid organ transplant/surgical (33%) wards, each with &lt; 3% positive conversion rate. Notably, no hematopoietic stem cell transplant patients tested positive for SARS-CoV-2 during the study period. Pediatric SARS-CoV-2 Testing Distributed by Race/Ethnicity Conclusion The positivity rate of universal pre-procedural and admission SARS-CoV-2 testing in pediatric patients was low in our inpatient cohort. Tests repeated &lt; 3 days from a negative result were especially low yield, suggesting limited utility of this practice. Diagnostic testing stewardship in certain populations may be useful, especially as community infection rates decline. Disclosures Michael J. Smith, MD, M.S.C.E, Merck (Grant/Research Support)Pfizer (Grant/Research Support) Rebekah W. Moehring, MD, MPH, UpToDate, Inc. (Other Financial or Material Support, Author Royalties)

scholarly journals Aprepitant and Fosaprepitant Use in Children and Adolescents at an Academic Medical Center

2014 ◽  
Vol 19 (2) ◽  
pp. 127-131 ◽  
Author(s):  
Alexandra Shillingburg ◽  
Lisa Biondo
Keyword(s):  
Children And Adolescents ◽  
Pediatric Patients ◽  
Medical Center ◽  
Academic Medical Center ◽  
Retrospective Chart Review ◽  
Primary Prophylaxis ◽  
Emetogenic Chemotherapy ◽  
Record System ◽  
Patients Âgés ◽  
Academic Medical

OBJECTIVE: To describe the use of aprepitant and fosaprepitant, a neurokinin 1 (NK-1) receptor inhibitor, in children and adolescents at a large academic medical center, for the prevention and management of chemotherapy-induced nausea and vomiting (CINV). METHODS: A retrospective chart review was conducted using an electronic medical record system to evaluate the use of aprepitant and fosaprepitant in all pediatric patients that were discharged from a single academic medical center between February 25, 2009 and May 25, 2012. RESULTS: Twenty-six patients were included in this review and received a total of 287 doses over the span of 114 cycles. Mean age was 10.1 years, with a range of 11 months to 17 years old. In 16 of 26 patients, aprepitant was used as the primary prophylaxis. Of those patients who received primary prophylaxis, 6 of 16 received it for highly emetogenic chemotherapy, and 10 of 16 received it for moderately emetogenic chemotherapy. Intravenous fosaprepitant was used in 7 of 26 patients, ages 13 to 17 (median 14) years old. No adverse effects attributable to aprepitant were reported. CONCLUSIONS: Use of aprepitant and fosaprepitant in pediatric patients appeared to be well tolerated. No currently published reports data using aprepitant in a patient younger than 32 months old, whereas we reported its use in patients as young as 11 months old.

scholarly journals Cochlear Implants in Single-Sided Deafness. Comparison Between Children and Adult Populations With Post-lingually Acquired Severe to Profound Hearing Loss

2021 ◽  
Vol 12 ◽  
Author(s):  
Nadia Falcón Benítez ◽  
Juan Carlos Falcón González ◽  
Ángel Ramos Macías ◽  
Silvia Borkoski Barreiro ◽  
Ángel Ramos de Miguel
Keyword(s):  
Hearing Loss ◽  
Speech Perception ◽  
Cochlear Implantation ◽  
Speech Test ◽  
Deaf Adults ◽  
Common Etiology ◽  
Single Sided Deafness ◽  
Positive Results ◽  
Auditory Lateralization

Objective: To determine audiological and clinical results of cochlear implantation (CI) comparing two populations with single-sided deafness (SSD): post-lingually deaf children between 6 and 12 years of age, and post-lingually deaf adults, in order to evaluate the effect of CI in different age groups.Design: Retrospective case review.Setting: Tertiary clinic.Patients and Method: Twenty-three children and twenty-one adult patients that were candidates for CI with single-side deafness were included. In all cases we evaluate: Speech perception thresholds; disyllabic words test (65 dB SPL) were performed in the modalities S0–SCI–SNH and Auditory Lateralization Test. The Speech, Spatial, and Qualities of Hearing Scale (SSQ) questionnaire was also used. All results were obtained after 12 months of CI activation.Results: In children, the most common etiology was idiopathic sensory-neural hearing loss. They showed positive results in the Auditory Lateralization Test. In the Speech Test, word recognition in noise improved from 2% preoperatively to 61.1% at a mean follow-up of 1 year (S0 condition) in children [test with signal in CI side 60% and signal normal hearing side (plugged) 31%]. The processor was used for &gt;12 h in all cases. With respect to the SSQ questionnaire, parents were more satisfied within the postoperative period than within the preoperative period. For adults, the most common etiology was idiopathic sudden sensorineural hearing loss (SNHL). Positive results in the Auditory Lateralization Test were found. With respect to the Speech Test in quiet conditions: Word recognition in noise improved from 5.7% preoperatively to 71.8% at a mean follow-up of 1 year [test with signal in CI side 68% and signal normal hearing side (plugged) 41%]. The processor was used for &gt;12 h. In the SSQ questionnaire, the post-operative results showed a beneficial effect of the CI. No adverse events were reported during the study period. No differences were found between children and adults in all tests in this study.Conclusions: Cochlear implantation in post-lingually deaf adults and children with SSD can achieve a speech perception outcome comparable with CI in conventional candidates. Improvements in spatial hearing were also observed. Careful patient selection and counseling regarding potential benefits are important to optimize outcomes.

Cochlear implantation in an intralabyrinthine acoustic neuroma patient after resection of an intracanalicular tumour

1996 ◽  
Vol 110 (6) ◽  
pp. 570-573 ◽  
Author(s):  
Tetsuya Tono ◽  
Yasuaki Ushisako ◽  
Tamotsu Morimitsu
Keyword(s):  
Cochlear Implant ◽  
Acoustic Neuroma ◽  
Cochlear Implantation ◽  
Therapeutic Strategy ◽  
Cochlear Nerve ◽  
Middle Fossa ◽  
Middle Fossa Approach ◽  
Tumour Removal ◽  
Bilateral Acoustic Neuroma

AbstractThis case study describes a therapeutic strategy using a cochlear implant for a bilateral acoustic neuroma deafened patient. The cochlear nerve had previously been sacrificed on one side during tumour removal, but on the remaining side a functioning cochlear nerve was assessed by electric promontory stimulation in spite of a neuroma extending into the vestibular labyrinth. The patient was successfully stimulated with a Nucleus 22- channel implant after removal of the intracanalicular portion of the neuroma via a middle fossa approach.

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