XVII Histopathologic Changes of the Temporal Bone in Paget's Disease

1942 ◽  
Vol 51 (1) ◽  
pp. 170-208 ◽  
Author(s):  
M. Tamari
Keyword(s):  
Temporal Bone ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Histopathologic Changes

Evidence of Osteoclastic Activity in the Human Temporal Bone

2017 ◽  
Vol 22 (4-5) ◽  
pp. 218-225 ◽  
Author(s):  
Takefumi Kamakura ◽  
Joseph B. Nadol Jr.
Keyword(s):  
Bone Remodeling ◽  
Temporal Bone ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Old Patients ◽  
Osteoclastic Activity ◽  
Human Temporal Bone ◽  
Group 2 ◽  
Anatomic Locations ◽  
Temporal Bones

Bone remodeling within the otic capsule has been reported to be inhibited especially at or near the cochlea, except under some pathological conditions such as otosclerosis, Paget's disease, or mastoiditis, when bone remodeling can occur. Microcavitations found in periosteal and endosteal layers of human temporal bone specimens without otosclerosis, Paget's disease, or inflammation as reported in the current study are consistent with osteoclastic bone resorption. Thirty-three temporal bones from 33 patients were prepared for light microscopy and classified into 4 groups: histologically proven dehiscence of the superior semicircular canal (SSCD) (n = 3, group 1), age 20 years or younger (n = 10, group 2), age 90 years or older and with otosclerosis (n = 10, group 3), and age 90 years or older without otosclerosis (n = 10, group 4). Microcavitation was seen at 7 anatomic locations in the temporal bone in all 4 groups, but not in the cochlea or vestibule. Microcavitation within the temporal bone is likely due to osteoclastic activity, and it is seen in both young and old patients, patients with and without otosclerosis, and in cases with SSCD.

scholarly journals Paget's disease in temporal bone

2018 ◽  
Author(s):  
A Alzahr ◽  
M Mansour ◽  
B Knof
Keyword(s):  
Temporal Bone ◽  
Paget’S Disease ◽  
Paget's Disease

XLVIII The Clinical Diagnosis of Paget's Disease of the Temporal Bone

1967 ◽  
Vol 76 (3) ◽  
pp. 611-623 ◽  
Author(s):  
Jack D. Clemis ◽  
John Boyles ◽  
Earl R. Harford ◽  
Jerry P. Petasnick
Keyword(s):  
Temporal Bone ◽  
Clinical Diagnosis ◽  
Paget’S Disease ◽  
Paget's Disease

Paget's Disease of the Temporal Bone

2006 ◽  
Vol 27 (8) ◽  
pp. 1199-1200 ◽  
Author(s):  
David C. Shonka ◽  
Bradley W. Kesser
Keyword(s):  
Temporal Bone ◽  
Paget’S Disease ◽  
Paget's Disease

scholarly journals A Case of Paget's Disease of the Temporal Bone, Having Been Progressed to Total Deafness

2006 ◽  
Vol 99 (3) ◽  
pp. 197-201
Author(s):  
Yurika Kimura ◽  
Mutsumi Sugiura ◽  
Nao Makino ◽  
Hideji Okuno ◽  
Ken Kitamura
Keyword(s):  
Temporal Bone ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Total Deafness

Paget's Disease of the Temporal Bone

1975 ◽  
Vol 84 (4_suppl2) ◽  
pp. 1-32 ◽  
Author(s):  
George T. Nager
Keyword(s):  
Temporal Bone ◽  
Progressive Disease ◽  
Paget’S Disease ◽  
Vestibular Function ◽  
Axial Skeleton ◽  
Paget's Disease ◽  
Vascular Changes ◽  
Osteitis Deformans ◽  
External Canal ◽  
Temporal Bones

Osteitis deformans Paget is a fairly common, heritable, sometimes progressive disease of bone which affects primarily the axial skeleton and may lead to deformity and weakness. It affects 3% of the population over forty years of age and males more frequently than females. The skull and temporal bones become involved in about two-thirds of the patients. Progressive involvement of the temporal bones may lead to alteration of position, increase in size and change of architecture of the petrous pyramid, external canal, middle ear and inner ear capsule. These changes in turn may produce impairment of hearing (about 30–50% of cases) and vestibular function (20–25%). The clinical, radiological, and pathological manifestations of Paget's disease of the temporal bone are discussed in detail and explained with photomicrographs. Examples of tumor formations and vascular changes are presented.

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