Temporal Bone Showing Otosclerosis, Paget's Disease and Adenocarcinoma

1977 ◽  
Vol 86 (3) ◽  
pp. 381-385 ◽  
Author(s):  
George Kelemen
Keyword(s):  
Temporal Bone ◽  
Paget’S Disease ◽  
Organ Of Corti ◽  
Paget's Disease ◽  
Serial Sectioning ◽  
Adjacent Organ ◽  
The Right ◽  
Temporal Bones

In a pair of temporal bones serial sectioning revealed widespread Paget's disease with otosclerosis on both sides and, at the right side, adenocarcinoma added. Stapedial fixation was produced on the right by otosclerosis, and on the left by Paget's disease. In the contest to reach the inner cochlear space, Paget was the winner on the left, where, at the tympanic scala, otosclerosis and Paget's disease almost met, while the immediately adjacent organ of Corti was uninvolved.

Evidence of Osteoclastic Activity in the Human Temporal Bone

2017 ◽  
Vol 22 (4-5) ◽  
pp. 218-225 ◽  
Author(s):  
Takefumi Kamakura ◽  
Joseph B. Nadol Jr.
Keyword(s):  
Bone Remodeling ◽  
Temporal Bone ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Old Patients ◽  
Osteoclastic Activity ◽  
Human Temporal Bone ◽  
Group 2 ◽  
Anatomic Locations ◽  
Temporal Bones

Bone remodeling within the otic capsule has been reported to be inhibited especially at or near the cochlea, except under some pathological conditions such as otosclerosis, Paget's disease, or mastoiditis, when bone remodeling can occur. Microcavitations found in periosteal and endosteal layers of human temporal bone specimens without otosclerosis, Paget's disease, or inflammation as reported in the current study are consistent with osteoclastic bone resorption. Thirty-three temporal bones from 33 patients were prepared for light microscopy and classified into 4 groups: histologically proven dehiscence of the superior semicircular canal (SSCD) (n = 3, group 1), age 20 years or younger (n = 10, group 2), age 90 years or older and with otosclerosis (n = 10, group 3), and age 90 years or older without otosclerosis (n = 10, group 4). Microcavitation was seen at 7 anatomic locations in the temporal bone in all 4 groups, but not in the cochlea or vestibule. Microcavitation within the temporal bone is likely due to osteoclastic activity, and it is seen in both young and old patients, patients with and without otosclerosis, and in cases with SSCD.

Paget's Disease of the Temporal Bone

1975 ◽  
Vol 84 (4_suppl2) ◽  
pp. 1-32 ◽  
Author(s):  
George T. Nager
Keyword(s):  
Temporal Bone ◽  
Progressive Disease ◽  
Paget’S Disease ◽  
Vestibular Function ◽  
Axial Skeleton ◽  
Paget's Disease ◽  
Vascular Changes ◽  
Osteitis Deformans ◽  
External Canal ◽  
Temporal Bones

Osteitis deformans Paget is a fairly common, heritable, sometimes progressive disease of bone which affects primarily the axial skeleton and may lead to deformity and weakness. It affects 3% of the population over forty years of age and males more frequently than females. The skull and temporal bones become involved in about two-thirds of the patients. Progressive involvement of the temporal bones may lead to alteration of position, increase in size and change of architecture of the petrous pyramid, external canal, middle ear and inner ear capsule. These changes in turn may produce impairment of hearing (about 30–50% of cases) and vestibular function (20–25%). The clinical, radiological, and pathological manifestations of Paget's disease of the temporal bone are discussed in detail and explained with photomicrographs. Examples of tumor formations and vascular changes are presented.

scholarly journals The defeat of the temporal bone in Paget’s disease as a cause of hearing loss in elderly and senile age

2018 ◽  
Vol 22 (4) ◽  
pp. 25-30
Author(s):  
Sergey A. Ivanov ◽  
Sergey G. Zhuravskii
Keyword(s):  
Hearing Loss ◽  
Medical Treatment ◽  
Temporal Bone ◽  
Cochlear Implantation ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Progressive Hearing Loss ◽  
Severe Hearing Loss ◽  
Structural Alterations ◽  
Temporal Bones

Paget’s disease of bone is a localized disorder of bone remodeling. These functional and structural alterations, interacting with the specific characteristics of the site of involvement, account for most of the complications of the disease. Bilateral progressive hearing loss is the most frequently encountered complication of Paget’s disease, because of the involvement of the temporal bones. There may be difficulty in distinguishing patients with presbycusis from those with Paget’s disease-related hearing loss. Pagetic hearing loss seems to be stabilized by effective medical treatment. For patients with severe hearing loss, cochlear implantation may be recommended.

Paget's Disease of the Temporal Bone

1975 ◽  
Vol 84 (22_suppl) ◽  
pp. 1-32 ◽  
Author(s):  
George T. Nager
Keyword(s):  
Temporal Bone ◽  
Progressive Disease ◽  
Paget’S Disease ◽  
Vestibular Function ◽  
Axial Skeleton ◽  
Paget's Disease ◽  
Vascular Changes ◽  
Osteitis Deformans ◽  
External Canal ◽  
Temporal Bones

Osteitis deformans Paget is a fairly common, heritable, sometimes progressive disease of bone which affects primarily the axial skeleton and may lead to deformity and weakness. It affects 3% of the population over forty years of age and males more frequently than females. The skull and temporal bones become involved in about two-thirds of the patients. Progressive involvement of the temporal bones may lead to alteration of position, increase in size and change of architecture of the petrous pyramid, external canal, middle ear and inner ear capsule. These changes in turn may produce impairment of hearing (about 30–50% of cases) and vestibular function (20–25%). The clinical, radiological, and pathological manifestations of Paget's disease of the temporal bone are discussed in detail and explained with photomicrographs. Examples of tumor formations and vascular changes are presented.

scholarly journals Bilateral temporal bone fractures: a case report

2017 ◽  
Vol 4 (1) ◽  
pp. 271
Author(s):  
Kiran Natarajan ◽  
Koka Madhav ◽  
A. V. Saraswathi ◽  
Mohan Kameswaran
Keyword(s):  
Hearing Loss ◽  
Case Report ◽  
Facial Nerve ◽  
Temporal Bone ◽  
Facial Paralysis ◽  
Bone Fractures ◽  
Clinical Manifestations ◽  
Csf Leak ◽  
The Right ◽  
Temporal Bones

<p>Bilateral temporal bone fractures are rare; accounting for 9% to 20% of cases of temporal bone fractures. Clinical manifestations include hearing loss, facial paralysis, CSF otorhinorrhea and dizziness. This is a case report of a patient who presented with bilateral temporal bone fractures. This is a report of a 23-yr-old male who sustained bilateral temporal bone fractures and presented 18 days later with complaints of watery discharge from left ear and nose, bilateral profound hearing loss and facial weakness on the right side. Pure tone audiometry revealed bilateral profound sensori-neural hearing loss. CT temporal bones &amp; MRI scans of brain were done to assess the extent of injuries. The patient underwent left CSF otorrhea repair, as the CSF leak was active and not responding to conservative management. One week later, the patient underwent right facial nerve decompression. The patient could not afford a cochlear implant (CI) in the right ear at the same sitting, however, implantation was advised as soon as possible because of the risk of cochlear ossification. The transcochlear approach was used to seal the CSF leak from the oval and round windows on the left side. The facial nerve was decompressed on the right side. The House-Brackmann grade improved from Grade V to grade III at last follow-up. Patients with bilateral temporal bone fractures require prompt assessment and management to decrease the risk of complications such as meningitis, permanent facial paralysis or hearing loss. </p>

Temporal Bone Findings in Hemifacial Microsomia

1978 ◽  
Vol 87 (3) ◽  
pp. 399-403 ◽  
Author(s):  
H. K. Chandra Sekhar ◽  
Nobuhtro Toktta ◽  
S. Alexic ◽  
M. Sachs ◽  
John F. Daly
Keyword(s):  
Temporal Bone ◽  
Ganglion Cells ◽  
Spiral Ganglion ◽  
Organ Of Corti ◽  
Petrous Bone ◽  
Nerve Fibers ◽  
Structural Abnormality ◽  
Hemifacial Microsomia ◽  
Partial Deficiency ◽  
The Right

— The temporal bone findings in a case of hemifacial microsomia are described with photographs. The right facial hypoplasia was associated with anophthalmia and microtia on the same side. The right petrous bone was hypoplastic and showed total superior dehiscence of the internal acoustic meatus. The otic capsule was deformed with an underdeveloped cochlear modiolus grossly deficient in spiral ganglion population. The spiralling cochlear shell showed partial deficiency of the interscalar septum between the middle and apical coils. The cochlear duct was shorter than that on the normal side; the organ of Corti however was normal. The vestibular system did not show any structural abnormality except for the degeneration and reduction of the Scarpa's ganglion cells and nerve fibers. An additional interesting fact was that the facial nerve was totally absent in the temporal bone except for its nervus intermedius component.

A Case of Tripple Extramammary Paget's Disease, Found on the Scrotum, the Right and Left Axilla.

1996 ◽  
Vol 58 (3) ◽  
pp. 413-416
Author(s):  
Gozo MURAMOTO ◽  
Takao UCHIHIRA ◽  
Toshiaki KAMEI ◽  
Toru HIROTA ◽  
Chidori ASAGAMI
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Extramammary Paget’S Disease ◽  
Left Axilla ◽  
The Right ◽  
Extramammary Paget's Disease

scholarly journals Paget's disease in temporal bone

2018 ◽  
Author(s):  
A Alzahr ◽  
M Mansour ◽  
B Knof
Keyword(s):  
Temporal Bone ◽  
Paget’S Disease ◽  
Paget's Disease
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