Some questions provoked by a chronic headache (with mixed migraine and cluster headache features) in a woman with a pineal cyst. Answers from a literature review

Cephalalgia ◽  
2010 ◽  
Vol 30 (9) ◽  
pp. 1031-1040 ◽  
Author(s):  
FJ Molina-Martínez ◽  
MC Jiménez-Martínez ◽  
B Vives-Pastor

The main known function of the pineal gland in humans is the production of melatonin. Benign cysts of the gland have been related to headache, although the mechanism of production of this assumed clinical manifestation has not been clearly determined, due to the lack of large prospective studies. The question is complicated by the fact that pineal cysts are frequently found on brain magnetic resonance imaging. Much has been published about the possible role of benign pineal cysts in the pathophisiology of headaches and the potential of melatonin in headache therapy, as well as in other disorders. The aim of this article is to review the current state of the suject. We have tried to place accurately the relation between headache and pineal cysts based on the available evidence, as well as the actual role of melatonin in physiology and pharmacology, more specifically in headache therapy. We include a clinical case to illustrate the subject.

2005 ◽  
Vol 58 (9) ◽  
pp. 1014-1021
Author(s):  
José L. Pérez-Vela ◽  
Ana Ramos-González ◽  
Luis F. López-Almodóvar ◽  
Emilio Renes-Carreño ◽  
Almudena Escribá-Bárcena ◽  
...  

Author(s):  
Pedro Clarós ◽  
Aymar Diandaga Maleka ◽  
Agnieszka Walag ◽  
Andrés Clarós

<p>The non-salivary and non-intestinal adenocarcinomas are glandular tumors that include cases of low grade with low metastatic potential and high-grade ones, with aggressive metastatic potential. We present a clinical case of a 47 years old patient, referred to an ENT specialist because of swelling of the inner corner of right eye. Computed tomography (CT) and magnetic resonance imaging showed a proliferation process. The histopathological examination of the tumor biopsy revealed a high grade, non-salivary and non-intestinal orbital adenocarcinoma. Afterwards we review the literature on the subject. The primary non-salivary and non-intestinal orbital adenocarcinoma is characterized by locoregional aggressiveness, making treatment difficult and often mutilating. The prognosis is generally unfavourable. The clinician must exclude a malignant process of lacrimal sac in any patient presenting with a mass of the inner corner of the eye, with the help of the CT associated with magnetic resonance imaging. At the slightest doubt, the biopsy must be obtained. The treatment is multidisciplinary.</p>


Medicinus ◽  
2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Novita Tirtaprawita ◽  
Wiradharma Wiradharma ◽  
Julius July

En plaque meningioma is at frontal region is difficult to be differentiated from osteoma, based on CT scan only. En plaque meningioma represents in 2-9% of all meningioma cases. Usually en plaque meningioma grows on the sphenoid wing, whereas only 1 % grows on the frontal and temporal bone. This case is female 37 year- old who presents with chronic headache and huge lump on her right forehead that she believes it slowly enlarges for the last 5 years. The Computerized Tomography scan (CT scan) shows thickening of the right fronto-temporal bone (3-4 cm) with the diameter of 12 cm and bony hard. Initial impression suggests it could be osteoma or fibrous dysplasia. After the MRI (Magnetic Resonance Imaging) with contrast, it shows a carpet like tumor underline the thickening bone, and it suggest an en plaque meningioma. For en plaque meningioma, we have to remove the abnormal duramater. We suggest that for a case with a wide thickening calvarian bone, it’s better to get the MRI of the head with contrast.


2020 ◽  
Vol 88 (3) ◽  
pp. 115-124
Author(s):  
TOLBA S. ABD ELGHAFFAR, M.Sc.; NAAILA A. ABU MADYAN, M.D. ◽  
NADIA A. METWALY, M.D.; LAILA A. SELIM, M.D.

2021 ◽  
Vol 11 (2) ◽  
pp. 378-385
Author(s):  
Tao Li ◽  
Kai Chen ◽  
Xianyue Quan

Functional magnetic resonance imaging (fMRI) was used to observe the activation response of the hypothalamus under different intensity electrical stimulation, and to explore the role of thalamus in the pain regulation network. Ten subjects were selected as normal subjects, and 41 °C and 51 °C were performed on the dorsal side of the right forearm of all subjects, respectively. CCHS mission-mode functional magnetic resonance (fMRI) scans (41 °C. CCHS-fMRI group and 51 °C CHS-fMRI group) were pre-processed with fMRI using SPM8. A single sample t-test was used to compare 41 °C CCHS-fMRI group and 51 °C. The CCHS-fMRI group underwent intragroup analysis to observe the activation of brain regions under two different temperature CHS, and recorded the activation intensity of the activation region. A paired t-test was used to explore the difference in activation between the PD group and the control group, and brain regions with statistically significant differences were analyzed. The activation intensity of the activated brain region was recorded, and the cause of the difference was analyzed. At the end of the trial, the visual analog scale (CVAS) was used to score the pain experienced by the subject at the stimulation temperature, and then the subject was subjected to a sensory quantification test (QST), including the measurement of thermal sensation (WS) and thermal pain (HP). At the same time, under the same intensity electrical stimulation, the activation signal of the lateral thalamus was stronger than that of the lateral thalamus, showing a contralateral advantage, while the bilateral thalamus lacked this manifestation. The thalamus should be an important component of the pain-regulating network. This region exhibits a segregationactivated phenomenon, and each region has its own unique stimulatory response characteristics, which helps to understand the role of the thalamus in the treatment of pain information.


2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Rafael Maffei Loureiro ◽  
Daniel Vaccaro Sumi ◽  
Marcelo Delboni Lemos ◽  
Hugo Luis de Vasconcelos Chambi Tames ◽  
Regina Lucia Elia Gomes ◽  
...  

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