Technical Evaluation of Newly-Developed Inorganic Membranes for Plasma Fractionation

1989 ◽  
Vol 12 (3) ◽  
pp. 195-199
Author(s):  
K. Ozawa ◽  
K. Ohashi ◽  
T. Ide ◽  
K. Sakai

Constant transmembrane pressure experiments were made by crossflow filtration to clarify sieving characteristics of microporous glass membranes for plasma fractionation. The distribution of pore diameters is more limited in the microporous glass membranes than in currently utilized synthetic polymer membranes. The filtration resistance of the concentration polarization layer is the dominant factor in plasma fractionation. Proteins are separated more sharply with a higher wall shear rate because of destruction of the concentration polarization layer formed on membrane surfaces. Plasma fractionation using a microporous glass membrane with a pore diameter of 15 nm may allow separation of albumin and IgG at higher wall shear rates. Cascade filtration techniques using microporous glass membranes with various pore diameters may be suitable for plasma fractionation.

Water ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 3605
Author(s):  
Zhou Yu ◽  
Xinmin Wang ◽  
Weiying Li ◽  
Sheng Chen

Based on CFD and film theory, filtration’s two-dimensional CFD model of the hollow membrane was established by integrating the mass transformation and the hydrodynamic transportation. Parameters of concentration polarization in the membrane channel (i.e., solute mass concentration, concentration polarization factors, and concentration polarization layer thickness) were estimated under different hydraulic conditions. In addition, the algorithm for the thickness of the concentration polarization layer has been improved. The results showed that decreasing the feed Reynolds number or increasing the transmembrane pressure can enhance the concentration polarization phenomena. Concentration polarization parameters increased sharply at the initial place (X/H < 25, where H is the entrance width, X is the distance from entrance) and then flatten out (X/H > 25) along the membrane channel; solute concentration and concentration polarization factors were arranged in a U-shape in the membrane channel’s cross-section. The improved algorithm could match well with cross section data, δ2H at X/H = 1, 25, and 200 are 0.038, 0.11, and 0.25, respectively, which can reasonably reflect the distribution of the concentration polarization phenomenon in the membrane channel.


MEMBRANE ◽  
1990 ◽  
Vol 15 (2) ◽  
pp. 72-77 ◽  
Author(s):  
HARUHIKO OHYA ◽  
SUSUMU SATO ◽  
AKIRA ISHII ◽  
YOUICHI NEGISHI ◽  
KANJI MATSUMOTO

2016 ◽  
Vol 116 (25) ◽  
Author(s):  
Inhee Cho ◽  
Wonseok Kim ◽  
Junsuk Kim ◽  
Ho-Young Kim ◽  
Hyomin Lee ◽  
...  

Nanoscale ◽  
2017 ◽  
Vol 9 (33) ◽  
pp. 11871-11880 ◽  
Author(s):  
Hyekyung Lee ◽  
Junsuk Kim ◽  
Hyeonsoo Kim ◽  
Ho-Young Kim ◽  
Hyomin Lee ◽  
...  

The new class of micro/nanofluidic diodes with an ideal perm-selective membrane were demonstrated at a wide concentration range from 10−5 M to 3 M. Moreover, the rectification factor was actively controlled by adjusting the external convective flows.


2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Endre Nagy ◽  
Gábor Borbély

The negative effect of the concentration polarization layer on the membrane separation is well known. How the mass transport parameters of the membrane matrix, e.g. the solubility coefficient, membrane Peclet number, can affect the concentration profile of the boundary layer, and consequently, the separation efficiency is not investigated in detail yet. This paper gives the suitable mathematical expressions, in order to predict the well known parameters as polarization modulus, enrichment factors, etc., taking into account the transport parameters for both the concentration boundary and the membrane layers, and analyses the concentration distribution and the polarization modulus. It has been shown that the transport properties of the membrane layer have significant effect on the concentration profiles of the boundary layer and thus, on the polarization modulus, enrichment factors, etc., as well. Thus, the well known equations, e.g. the polarization modulus, enrichment factor given in the literature [see e.g. Equations (2) and (3)], could be considered as approaches.


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