Curative Intent Surgery of Oral Malignant Melanoma and Regional Lymph Node Biopsy Assessment in 25 Dogs: 2006–2017

2022 ◽  
pp. 089875642110723
Author(s):  
Matthew L. Raleigh ◽  
Mark M. Smith ◽  
Kendall Taney

Medical records were searched for dogs that had received curative intent surgery for oral malignant melanoma and ipsilateral excisional regional lymph node biopsy. Twenty-seven dogs were operated on and 25 dogs of these dogs met the inclusion criteria of signalment, post-excision margin status, presence of metastasis for each biopsied lymphocentrum, survival time post-excision, presence of recurrence or metastasis at follow-up or at death/euthanasia, location of the primary tumor, and any postoperative adjuvant treatment. These 25 dogs had complete tumor excision with tumor-free margins and 19 (76%) had postoperative adjuvant therapy. Median survival time after excision for the dogs in this study was 335.5 days. Results of this study support previous work that documents prolonged survival time following complete excision of oral malignant melanoma with tumor-free surgical margins in dogs. Additionally, 4 dogs (16%) had histologically confirmed regional lymph node metastasis at the time of definitive surgery.

2005 ◽  
Vol 28 (6) ◽  
pp. 403-407 ◽  
Author(s):  
Richard R. Clark ◽  
Taimur Shoaib ◽  
David S. Soutar ◽  
Henry W. Gray ◽  
Rodney G. Bessent ◽  
...  

2014 ◽  
pp. 1
Author(s):  
Ana Drummond-Lage ◽  
Alberto Wainstein ◽  
Milhem Kansaon ◽  
Gustavo Bretas ◽  
Rodrigo Almeida ◽  
...  

2018 ◽  
Vol 46 (6) ◽  
pp. 1027-1031 ◽  
Author(s):  
Roman Kia Rahimi-Nedjat ◽  
Bilal Al-Nawas ◽  
Andrea Tuettenberg ◽  
Keyvan Sagheb ◽  
Stephan Grabbe ◽  
...  

Skin Cancer ◽  
2021 ◽  
Vol 36 (2) ◽  
pp. 173-179
Author(s):  
Tatsuya TSUDA ◽  
Yoshiro ABE ◽  
Soushi ISHIDA ◽  
Kazuhide MINEDA ◽  
Yutaro YAMASHITA ◽  
...  

2009 ◽  
Vol 75 (7) ◽  
pp. 551-557
Author(s):  
Benjamin C. Wood ◽  
Lisa R. David ◽  
Anthony J. Defranzo ◽  
John H. Stewart ◽  
Perry Shen ◽  
...  

Traditionally, sentinel lymph node biopsy (SLNB) is performed at the time of mastectomy and reconstruction. However, several groups have advocated SLNB as a separate outpatient procedure before mastectomy, when immediate reconstruction is planned, to allow for complete pathologic evaluation. The purpose of this study was to determine the impact of intraoperative analysis of SLNB on the reconstructive plan when performed at the same time as definitive surgery. A retrospective review was conducted of all mastectomy cases performed at a single institution between September 1998 and November 2007. Of the 747 mastectomy cases reviewed, SLNB was conducted in 344 cases, and there was immediate breast reconstruction in 193 of those cases. There were 27 (7.8%) false negative and three (0.9%) false positive intraoperative analysis of SLNB. Touch preparation analysis from the SLNB changed the reconstructive plan in four (2.1%) cases. In our experience, SLNB can be performed at the time of mastectomy with minimal impact on the reconstructive plan. A staged approach incurs significant additional expense, increases the delay in initiation of systemic therapy and the propensity of procedure-related morbidity; therefore, SLNB should not be performed as a separate procedure before definitive surgery with immediate breast reconstruction.


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