High-risk human papillomavirus infection among women living with HIV in Latin America and the Caribbean: A systematic review and meta-analysis

2021 ◽  
pp. 095646242110374
Author(s):  
María Caicedo-Martínez ◽  
Ginna Fernández-Deaza ◽  
Camila Ordóñez-Reyes ◽  
Peter Olejua ◽  
Bernardo Nuche-Berenguer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Latin America ◽  
Human Papillomavirus ◽  
High Risk ◽  
Meta Analysis ◽  
Women Living With Hiv ◽  
Hpv Prevalence ◽  
High Prevalence ◽  
The Caribbean ◽  
Living With Hiv

We carried out a systematic review to summarize available data regarding prevalence of high-risk human papillomavirus (HR-HPV) among women living with HIV (WLHIV) in Latin America and the Caribbean (LAC). A literature search in PubMed and LILACS was conducted and supplemented with cross-referencing and grey literature. The primary outcome was prevalence of HR-HPV by age as a major determinant of HPV infection. Pooled prevalence and weighted averages were obtained. A random effects meta-analysis conducted for HPV- and HIV-associated factors. In total, 6157 women from 19 cross-sectional studies were included. Weighted prevalence of HR-HPV in WLHIV was 51.0% (95% CI 42.8–59.1, I2 = 97.4%) with a bimodal trend by age. No association between antiretroviral therapy and HR-HPV prevalence was observed, but low CD4 cell count was associated (PR 1.64, 95% CI 1.07–2.52). Although not significant, a higher HR-HPV prevalence was observed with Hybrid Capture 2 versus PCR. The high prevalence of HR-HPV among WLHIV in LAC underlines the need for improved cervical cancer prevention and early detection in this vulnerable population. Moreover, the high prevalence across age groups, and particularly in young women, deserves careful consideration for defining target populations of HPV-based screening and HPV immunization programs.

scholarly journals Type-Specific HPV Prevalence in Cervical Cancer and High-Grade Lesions in Latin America and the Caribbean: Systematic Review and Meta-Analysis

PLoS ONE ◽  
2011 ◽  
Vol 6 (10) ◽  
pp. e25493 ◽  
Author(s):  
Agustín Ciapponi ◽  
Ariel Bardach ◽  
Demián Glujovsky ◽  
Luz Gibbons ◽  
María Alejandra Picconi
Keyword(s):  
Systematic Review ◽  
Cervical Cancer ◽  
Latin America ◽  
Meta Analysis ◽  
High Grade ◽  
Hpv Prevalence ◽  
The Caribbean

scholarly journals Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Mohammad Farahmand ◽  
Mohsen Moghoofei ◽  
Abolfazl Dorost ◽  
Saeedeh Abbasi ◽  
Seyed Hamidreza Monavari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Papillomavirus ◽  
Sex Workers ◽  
Female Sex Workers ◽  
Meta Analysis ◽  
Hpv Infection ◽  
Hpv Prevalence ◽  
High Prevalence ◽  
The World ◽  
Hpv Types

Abstract Background: Female sex workers (FSWs) are amongst the most susceptible groups to acquire human papillomavirus (HPV) infection and consequently, to develop cervical intraepithelial neoplasia and cervical cancer. This is the first systematic review and meta-analysis to provide estimates of the pooled prevalence of HPV infection and the distribution of HPV types among FSWs across the world. Methods: Five computerized databases were searched for relevant studies published since the inception date of databases to September 2019. The pooled HPV prevalence was calculated by the random effect model described by DerSimonian-Laird. Subgroup analysis was performed to identify the probable sources of heterogeneity. The meta-analysis was performed using the “Metaprop” function in the R package Meta. Results: Sixty-two studies involving 21402 FSWs from 33 countries were included in this meta-analysis, and the pooled HPV prevalence was 42.60% (95% confidence interval (CI): 38.58%-46.71%). HPV-16 (10.16%, 95% CI: 8.20%–12.51%), HPV-52 (7.98%, 95% CI: 5.91%–10.70%), and HPV-53 (6.01%, 95% CI: 4.40%–8.15%) were the most common high-risk HPV types identified among FSWs. The pooled estimated prevalence of HPV infection among FSWs before and after 2010 were slightly different, 43.64% (95% CI: 36.12%-51.46%) and 41.97% (95% CI: 37.28%-46.81%), respectively. Conclusion: Due to the high prevalence of HPV infection, particularly with high-risk types, FSWs have a great susceptibility to the development of cervical and vaginal cancers. Furthermore, they can transmit their infection to their clients, which may result in a high prevalence of HPV and the incidence of HPV-associated malignancies among the general population.

Prevalence of human papillomavirus infection in Brazilian women living with HIV: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Brenda Evelin Barreto da Silva ◽  
Lígia Mara Dolce Lemos ◽  
Marcus Vinicius Batista ◽  
Carlos Anselmo Lima ◽  
Paulo Ricardo Martins-Filho ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Papillomavirus ◽  
Meta Analysis ◽  
Women Living With Hiv ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Living With Hiv

scholarly journals Prevalence and genotype distribution of genital human papillomavirus infection in female sex workers in the world: a systematic review and meta-analysis

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Mohammad Farahmand ◽  
Mohsen Moghoofei ◽  
Abolfazl Dorost ◽  
Saeedeh Abbasi ◽  
Seyed Hamidreza Monavari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Papillomavirus ◽  
Sex Workers ◽  
Female Sex Workers ◽  
Meta Analysis ◽  
Hpv Infection ◽  
Hpv Prevalence ◽  
High Prevalence ◽  
The World ◽  
Hpv Types

Abstract Background Female sex workers (FSWs) are amongst the most susceptible groups to acquire human papillomavirus (HPV) infection and consequently, to develop cervical intraepithelial neoplasia and cervical cancer. This is the first systematic review and meta-analysis to provide estimates of the pooled prevalence of HPV infection and the distribution of HPV types among FSWs across the world. Methods Five computerized databases were searched for relevant studies published since the inception date of databases to September 2019. The pooled HPV prevalence was calculated by the random effect model described by DerSimonian-Laird. Subgroup analysis was performed to identify the probable sources of heterogeneity. The meta-analysis was performed using the “Metaprop” function in the R package Meta. Results Sixty-two studies involving 21,402 FSWs from 33 countries were included in this meta-analysis, and the pooled HPV prevalence was 42.6% (95% confidence interval (CI): 38.5–46.7%). HPV-16 (10.1, 95% CI: 8.2–12.5%), HPV-52 (7.9, 95% CI: 5.9–10.7%), and HPV-53 (6.0, 95% CI: 4.4–8.1%) were the most common high-risk HPV types identified among FSWs. The pooled estimated prevalence of HPV infection among FSWs before and after 2010 were slightly different, 43.6% (95% CI: 36.1–51.4%) and 41.9% (95% CI: 37.2–46.8%), respectively. Conclusion Due to the high prevalence of HPV infection, particularly with high-risk types, FSWs have a great susceptibility to the development of cervical and vaginal cancers. Furthermore, they can transmit their infection to their clients, which may result in a high prevalence of HPV and the incidence of HPV-associated malignancies among the general population.

scholarly journals Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Mohammad Farahmand ◽  
Mohsen Moghoofei ◽  
Abolfazl Dorost ◽  
Saeedeh Abbasi ◽  
Seyed Hamidreza Monavari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Papillomavirus ◽  
Sex Workers ◽  
Female Sex Workers ◽  
Meta Analysis ◽  
Hpv Infection ◽  
Hpv Prevalence ◽  
High Prevalence ◽  
The World ◽  
Hpv Types

Abstract Background: Female sex workers (FSWs) are amongst the most susceptible groups to acquire human papillomavirus (HPV) infection and consequently, to develop cervical intraepithelial neoplasia and cervical cancer. This is the first systematic review and meta-analysis to provide estimates of the pooled prevalence of HPV infection and the distribution of HPV types among FSWs across the world. Methods: Five computerized databases were searched for relevant studies published since the inception date of databases to September 2019. The pooled HPV prevalence was calculated by the random effect model described by DerSimonian-Laird. Subgroup analysis was performed to identify the probable sources of heterogeneity. The meta-analysis was performed using the “Metaprop” function in the R package Meta. Results: Sixty-two studies involving 21402 FSWs from 33 countries were included in this meta-analysis, and the pooled HPV prevalence was 42.6% (95% confidence interval (CI): 38.5%-46.7%). HPV-16 (10.1%, 95% CI: 8.2%–12.5%), HPV-52 (7.9%, 95% CI: 5.9%–10.7%), and HPV-53 (6.0%, 95% CI: 4.4%–8.1%) were the most common high-risk HPV types identified among FSWs. The pooled estimated prevalence of HPV infection among FSWs before and after 2010 were slightly different, 43.6% (95% CI: 36.1%-51.4%) and 41.9% (95% CI: 37.2%-46.8%), respectively. Conclusion: Due to the high prevalence of HPV infection, particularly with high-risk types, FSWs have a great susceptibility to the development of cervical and vaginal cancers. Furthermore, they can transmit their infection to their clients, which may result in a high prevalence of HPV and the incidence of HPV-associated malignancies among the general population.

scholarly journals Prevalence of hepatitis B in people living with HIV/AIDS in Latin America and the Caribbean: a systematic review and meta-analysis

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Fatima Mitiko Tengan ◽  
Edson Abdala ◽  
Marisa Nascimento ◽  
Wanderley Marques Bernardo ◽  
Antonio Alci Barone
Keyword(s):  
Systematic Review ◽  
Latin America ◽  
Hepatitis B ◽  
Meta Analysis ◽  
People Living With Hiv ◽  
The Caribbean ◽  
Living With Hiv ◽  
Hiv Aids

scholarly journals Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Mohammad Farahmand ◽  
Mohsen Moghoofei ◽  
Seyed Hamidreza Monavari ◽  
Seyed Jalal Kiani ◽  
Ahmad Tavakoli
Keyword(s):  
Systematic Review ◽  
Human Papillomavirus ◽  
Sex Workers ◽  
Female Sex Workers ◽  
Meta Analysis ◽  
Hpv Infection ◽  
Hpv Prevalence ◽  
High Prevalence ◽  
The World ◽  
Hpv Types

Abstract Background: Female sex workers (FSWs) are amongst the most susceptible groups to acquire human papillomavirus (HPV) infection and consequently, to develop cervical intraepithelial neoplasia and cervical cancer. This is the first systematic review and meta-analysis to provide estimates of the pooled prevalence of HPV infection and distribution of HPV types among FSWs across the world. Methods: Five computerized databases were searched for relevant studies published since the inception date of databases to September 2019. The pooled HPV prevalence was calculated by the random effect model described by DerSimonian-Laird. Subgroup analysis was performed to identify the probable sources of heterogeneity. The meta-analysis was performed using the “Metaprop” function in the R package Meta. Results: Sixty-six studies involving 22938 FSWs from 34 countries were included in this meta-analysis, and the pooled HPV prevalence was 41.97% (95% confidence interval (CI): 37.99%-46.05%). HPV-16 (10.42%, 95% CI: 8.61%–12.55%), HPV-52 (7.76%, 95% CI: 5.75%–10.39%), and HPV-53 (6.09%, 95% CI: 4.55%–8.12%) were the most common high-risk HPV types identified among FSWs. The polled estimated prevalence of HPV infection among FSWs before and after 2010 were slightly different, 43.64% (95% CI: 36.12%-51.46%) and 41.01% (95% CI: 36.35%-45.83%), respectively. Conclusion: Due to the high prevalence of HPV infection, particularly with high-risk types, FSWs have a great susceptibility to the development of cervical and vaginal cancers. Furthermore, they can transmit their infection to their clients, which may result in a high prevalence of HPV and incidence of HPV-associated malignancies among the general population.

scholarly journals Prevalence and Genotype Distribution of Genital Human Papillomavirus Infection in Female Sex Workers in the World: a Systematic Review and Meta-Analysis

2019 ◽  
Author(s):  
Mohammad Farahmand ◽  
Seyed Hamidreza Monavari ◽  
Mohsen Moghoofei ◽  
Seyed Jalal Kiani ◽  
Mehdi Tavakoli ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Papillomavirus ◽  
Sex Workers ◽  
Female Sex Workers ◽  
Meta Analysis ◽  
Hpv Infection ◽  
Hpv Prevalence ◽  
High Prevalence ◽  
The World ◽  
Hpv Types

Abstract Background: Female sex workers (FSWs) are amongst the most susceptible groups to acquire Human papillomavirus (HPV) infection and consequently, to develop cervical intraepithelial neoplasia and cervical cancer. This is the first systematic review and meta-analysis to provide estimates of the pooled prevalence of HPV infection and distribution of HPV types among FSWs across the world. Methods: Five computerized databases were searched for relevant studies published since the inception date of databases to September 2019. The pooled HPV prevalence was calculated by the random effect model described by DerSimonian-Laird. Subgroup analysis was performed to identify the probable source of heterogeneity. The meta-analysis was performed using the “Metaprop” function in the R package Meta. Results: Sixty-six studies involving 22938 FSWs from 34 countries were included in this meta-analysis, and the pooled HPV prevalence was 41.97% (95% confidence interval (CI): 37.99%-46.05%). HPV-16 (10.42%, 95% CI: 8.61%–12.55%), HPV-52 (7.76%, 95% CI: 5.75%–10.39%), and HPV-53 (6.09%, 95% CI: 4.55%–8.12%) were the most common high-risk HPV types identified among FSWs. Geographically, the highest and the lowest prevalence of HPV were obtained from Hungary (82.35%, 95%CI: 65.90%–91.85%) and Mexico (13.30%, 95%CI: 1.67%–58.06%), respectively. Conclusion: Due to the high prevalence of HPV infection, particularly with high-risk types, FSWs have a great susceptibility to the development of cervical and vaginal cancers. Furthermore, they can transmit their infection to their clients, which may result in a high prevalence of HPV and incidence of HPV-associated malignancies among the general population.

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