Survey of beef bulls in Brazil to assess their role as source of infectious agents related to cow infertility

2021 ◽  
pp. 104063872110506
Author(s):  
Silvia D. Carli ◽  
Maria E. Dias ◽  
Maria E. R. J. da Silva ◽  
Gabriela M. Breyer ◽  
Franciele M. Siqueira

Poor reproductive performance in beef cattle caused by infectious agents results in major financial losses as a result of reduced pregnancy rates and extended calving intervals. Bulls can be subclinical chronic carriers of bacterial and protozoal agents involved in cow infertility, such as Campylobacter fetus subsp. venerealis, Ureaplasma diversum, Mycoplasma bovigenitalium, Mycoplasma bovis, and Tritrichomonas foetus. Bulls harbor these microorganisms in their preputial crypts and transmit the agents to cows during natural mating. To obtain an overview of the etiologic agents in the preputial mucus of bulls, we aimed to identify, by PCR assay, C. fetus subsp. venerealis, M. bovis, U. diversum, M. bovigenitalium, and T. foetus in Brazilian bulls from farms with high infertility rates. We collected preputial mucus from 210 bulls on 18 beef cattle farms in Brazil between 2019 and 2020. We found at least one of the infectious agents that we were studying in bulls on 16 of the 18 beef cattle farms tested. We detected at least one infectious agent from 159 of 210 (76%) bulls tested, namely C. fetus subsp. venerealis, M. bovis, U. diversum, M. bovigenitalium, and T. foetus in 87 (55%), 84 (53%), 45 (28%), 28 (18%), and 1 (0.6%) animal, respectively. We found 95 bulls (60%) positive for only 1 etiologic agent (single infection) and 64 bulls (40%) carried multiple agents. Our results demonstrate the occurrence of bacterial and protozoal infectious agents that may be related to infertility in Brazilian beef cattle herds.

2017 ◽  
Vol 9 (1) ◽  
pp. e2017035
Author(s):  
Francesco Zallio ◽  
Giulia Limberti ◽  
Marco Ladetto

Several infectious agents appear to provide a proliferative signal -- “antigen-drive” – that  could be implicated in the pathogenesis of various type of Non-Hodgkin Lymphoma (NHL). A classical model of infection-driven lymphoprolipherative disorder is Helicobacter pylori-induced gastric MALT lymphoma, where antibiotic therapy allows eradication of both the infectious agent and the clonal B-cell expansion;  following the footsteps of these example, several retrospective studies have found a correlation with other pathogens and B-cell Lymphomas, adding new important informations about pathogenesis and laying the groundwork for chemotherapy-free treatments.Although no clear association with infectious agents has yet been identified for Follicular Lymphoma (FL), a growing number of biological and clinical observations suggests that interaction with physiological and pathological microbial populations might play a role also in this subtype of lymphoma: in the last years epidemiological studies investigating the association of known risk factors and FL found a potential correlation with viral or bacterial infections; moreover recent findings about the stimulation of FL clones support the importance of microbial exposure to lymphomagenesis and disease progression.In the following review we make an attempt to find tangible evidences in favor of a role of either physiological and pathological exogenous microbial species in the pathogenesis of FL, and try to integrate the findings coming from epidemiological, biological and interventional studies to define future  novel treatment and prevention strategies for FL.


2011 ◽  
Vol 129 (1) ◽  
pp. 20-29 ◽  
Author(s):  
N.T. Pegolo ◽  
D. Laloë ◽  
H.N. de Oliveira ◽  
R.B. Lôbo ◽  
M.-N. Fouilloux
Keyword(s):  

2021 ◽  
Vol 51 (8) ◽  
Author(s):  
Eduardo Lara Ribeiro ◽  
Patrícia Tiemi Fujimura ◽  
Carlos Ueira-Vieira ◽  
Luiz Ricardo Goulart ◽  
Telma Maria Alves ◽  
...  

ABSTRACT: Bovine genital campylobacteriosis (BGC) is a venereal and subclinical disease that affects the fertility of cattle herds, and it is caused by Campylobacter fetus subsp. venerealis . This study selected peptides mimetic to the BGC-causing agent from a phage library. Phage display is a technique that applies bacteriophage libraries that reveal peptides fused to the viral capsid in biological selections against target proteins. Biopannings were performed for biological selection in the phage library using rabbit hyperimmune serum and C. fetus subsp. venerealis protein extract. Five selected heptapeptides were considered mimetic to Cfv-NCTC 10354 based on the results of bioinformatics analysis and assays with hyperimmune serum and cervicovaginal mucus obtained from heifers. ALASLPL and LSYLFPP were the most reactive peptides and considered promising as possible mimetic immunogens for C. fetus subsp. venerealis.


2020 ◽  
Vol 14 (1) ◽  
pp. 44-58
Author(s):  
Achmad Sambodo ◽  
Agustina Widyasworo ◽  
Resti Yuliana Rahmawati

This study aims to determine the characteristics of breeders with regard to the ability to keep beef cattle in Klampok Village, Sananwetan District, Blitar City. The material in this study concerns beef cattle farms in Klampok sub-district, sananwetan sub-district, Blitar city using quantitative research methods in the form of case studies with 33 farmer respondents. Data collection methods are conducted through surveys, pre-questioned interviews and observation. The results obtained from this study are that the ability to raise beef cattle is appropriate in the category. Breeding experience has a significant effect on the ability to keep beef cattle, as Klampok has had a business for raising beef cattle for a long time, while age and education level have no effect because age and education level in the study area are relative. uniform so that they have no effect, then the number of animal possession has no effect. because the breeders in the Klampok sub-district consider beef cattle only as an afterthought, so it has no significant effect on the ability to keep beef cattle


2017 ◽  
Vol 210 ◽  
pp. 183-187 ◽  
Author(s):  
Cristina Rodriguez ◽  
Djalal-Eddine Hakimi ◽  
Raphael Vanleyssem ◽  
Bernard Taminiau ◽  
Johan Van Broeck ◽  
...  

2016 ◽  
Vol 227 (10) ◽  
Author(s):  
Helen M. Sanchez ◽  
Cristina Echeverria ◽  
Vanessa Thulsiraj ◽  
Amy Zimmer-Faust ◽  
Ariel Flores ◽  
...  

2020 ◽  
Vol 30 (1-6) ◽  
pp. 2-8
Author(s):  
Bhaskara L. Reddy ◽  
Milton H., Jr. Saier

For decades it has been known that infectious agents including pathogenic protozoans, bacteria, and viruses, adapted to a particular animal host, can mutate to gain the ability to infect another host, and the mechanisms involved have been studied in great detail. Although an infectious agent in one animal can alter its host range with relative ease, no example of a plant virus changing its host organism to an animal has been documented. One prevalent pathway for the transmission of infectious agents between hosts involves ingestion of the flesh of one organism by another. In this article we document numerous examples of viral and prion diseases transmitted by eating animals. We suggest that the occurrence of cross-species viral epidemics can be substantially reduced by shifting to a more vegetarian diet and enforcing stricter laws that ban the slaughter and trade of wild and endangered species.


2017 ◽  
Vol 142 ◽  
pp. 39-45 ◽  
Author(s):  
Katja Hille ◽  
Inga Ruddat ◽  
Annette Schmid ◽  
Johanna Hering ◽  
Maria Hartmann ◽  
...  

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