Toward better characterization of restricted and unusual interests in youth with autism

Autism ◽  
2021 ◽  
pp. 136236132110567
Author(s):  
Mirko Uljarević ◽  
Gail A Alvares ◽  
Morgan Steele ◽  
Jaelyn Edwards ◽  
Thomas W Frazier ◽  
...  
Keyword(s):  
Video Games ◽  
Cognitive Functioning ◽  
Children And Adolescents ◽  
Current Knowledge ◽  
Clinical Importance ◽  
Visual Modality ◽  
Restricted Interests ◽  
High Prevalence ◽  
Communication Impairments ◽  
Mechanical Objects

Despite their high prevalence and clinical importance in autism, unusual and restricted interests remain under-researched and poorly understood. This study aimed to characterize the frequency and type of interests in autism by coding caregivers’ open-ended responses in a sample of 237 autistic children and adolescents ( Mage = 8.27 years, SDage = 4.07; range: 2.08–18.25 years). It further aimed to explore the effects of age, sex, cognitive functioning and social and communication deficits on the number and type of interests. We found that 75% of autistic youth had at least one interest and that 50% of those children showed two or more different interests. The most frequent interests were sensory-based (43%), with a majority of these interests relating to the visual modality. Interest within vehicles/transportation, fictional characters, television/digital versatile disk/movies, computers, and video games, constructive, mechanical objects, animals and plants, and attachment to specific objects were also prevalent. Logistic regression showed that being male, having a co-occurring intellectual disability and having more severe social and communication impairments were associated with a higher probability of having one or more restricted interests. Sex was significantly associated with the type (χ2 = 37.52, Phi = 0.37, p = 0.021) of restricted interests, with females showing a significantly higher percentage of creative interests and males significantly higher percentage of interest in characters, vehicles/transportation, computers/video games, mechanical objects and constructive interests. Theoretical and measurement implications are discussed. Lay abstract Despite being highly prevalent among people with autism, restricted and unusual interests remain under-researched and poorly understood. This article confirms that restricted interests are very frequent and varied among children and adolescents with autism. It also further extends current knowledge in this area by characterizing the relationship between the presence, number, and type of restricted interests with chronological age, sex, cognitive functioning, and social and communication symptoms.

Association of Micro RNA and Postoperative Cognitive Dysfunction: A Review

2020 ◽  
Vol 20 (17) ◽  
pp. 1781-1790
Author(s):  
Noor Anisah Abu Yazit ◽  
Norsham Juliana ◽  
Srijit Das ◽  
Nur Islami Mohd Fahmi Teng ◽  
Nadia Mohd Fahmy ◽  
...  
Keyword(s):  
Cognitive Dysfunction ◽  
Chromosomal Abnormalities ◽  
Current Knowledge ◽  
System Development ◽  
Genetic Disorder ◽  
Postoperative Cognitive Dysfunction ◽  
Clinical Importance ◽  
Nervous System Development ◽  
Micro Rna ◽  
A Genome

Postoperative Cognitive Dysfunction (POCD) refers to the condition of neurocognitive decline following surgery in a cognitive and sensory manner. There are several risk factors, which may be life-threatening for this condition. Neuropsychological assessment of this condition is very important. In the present review, we discuss the association of apolipoprotein epsilon 4 (APOE ε4) and few miRNAs with POCD, and highlight the clinical importance for prognosis, diagnosis and treatment of POCD. Microarray is a genome analysis that can be used to determine DNA abnormalities. This current technique is rapid, efficient and high-throughout. Microarray techniques are widely used to diagnose diseases, particularly in genetic disorder, chromosomal abnormalities, mutations, infectious diseases and disease-relevant biomarkers. MicroRNAs (miRNAs) are a class of non-coding RNAs that are widely found distributed in eukaryotes. Few miRNAs influence the nervous system development, and nerve damage repair. Microarray approach can be utilized to understand the miRNAs involved and their pathways in POCD development, unleashing their potential to be considered as a diagnostic marker for POCD. This paper summarizes and identifies the studies that use microarray based approaches for POCD analysis. Since the application of microarray in POCD is expanding, there is a need to review the current knowledge of this approach.

scholarly journals Active Video Games for Improving Mental Health and Physical Fitness—An Alternative for Children and Adolescents during Social Isolation: An Overview

2021 ◽  
Vol 18 (4) ◽  
pp. 1641 ◽  
Author(s):  
Isis Kelly dos Santos ◽  
Rafaela Catherine da Silva Cunha de Medeiros ◽  
Jason Azevedo de Medeiros ◽  
Paulo Francisco de Almeida-Neto ◽  
Dianne Cristina Souza de Sena ◽  
...  
Keyword(s):  
Mental Health ◽  
Video Games ◽  
Physical Fitness ◽  
Children And Adolescents ◽  
Social Isolation ◽  
Systematic Reviews ◽  
Cochrane Library ◽  
Active Video Games ◽  
Moderate Quality ◽  
Active Video

The aim of this study was to synthesize the evidence on the effects of active video games (AVGs) on mental health, physical fitness and body composition of children and adolescents. A search was conducted in the following databases: PubMed; MEDLINE (by Ovid); SportDiscus, Cochrane library systematic reviews (CENTRAL) and EMBASE with no language restrictions during October 2020. Reviews on the use of AVGs were included in the study. We use the AMSTAR (A MeaSurement Tool to Assess systematic Reviews) scale to analyze the methodological quality of the studies. Seventeen systematic reviews and meta-analyzes were included on the effects of AVGs with 30 to 4728 children and adolescents of both sexes with ages ranging from 6 to 19 years. In five studies, the population was overweight or obese. Regarding the quality, 12 studies were of moderate quality, two had high quality, two had low quality and one showed very low quality. The analyzed data indicate that the use of AVGs with a frequency of 1 to 3 times a week with durations of between 10 and 90 min per day shows positive effects on mental health and physical functioning. There was moderate quality evidence that AVGs can result in benefits for self-esteem, increased energy expenditure, physical activity and reduced body mass index in children and adolescents who used AVGs in the home environment. Further research is needed on this tool to help in the process of social isolation and consequently in promoting health and well-being.

scholarly journals Child maltreatment, cognitive functions and the mediating role of mental health problems among maltreated children and adolescents in Uganda

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Herbert E. Ainamani ◽  
Godfrey Z. Rukundo ◽  
Timothy Nduhukire ◽  
Eunice Ndyareba ◽  
Tobias Hecker
Keyword(s):  
Mental Health ◽  
Working Memory ◽  
Child Maltreatment ◽  
Executive Functions ◽  
Cognitive Functioning ◽  
Children And Adolescents ◽  
Mental Health Problems ◽  
Depression Scale ◽  
Well Being ◽  
Health Problems

Abstract Background Child maltreatment poses high risks to the mental health and cognitive functioning of children not only in childhood but also in later life. However, it remains unclear whether child maltreatment is directly associated with impaired cognitive functioning or whether this link is mediated by mental health problems. Our study aimed at examining this research question among children and adolescents in Uganda. Methods A sample of 232 school-going children and adolescents with a mean age of 14.03 (SD = 3.25) was assessed on multiple forms of maltreatment using the Maltreatment and Abuse Chronology Exposure—Pediatric Version (pediMACE). Executive functions were assessed by the Tower of London task and working memory by the Corsi Block Tapping task, while mental health problems were assessed using the Child PTSD Symptom Scale for PTSD and the Center for Epidemiological Studies Depression Scale for Children (CES-DC). Results In total, 232 (100%) of the participant reported to have experienced at least one type of maltreatment in their lifetime including emotional, physical, and sexual violence as well as neglect. We found a negative association between child maltreatment and executive functions (β = − 0.487, p < 0.001) and working memory (β = − 0.242, p = 0.001). Mental health problems did not mediate this relationship. Conclusions Child maltreatment seems to be related to lower working memory and executive functioning of affected children and adolescents even after controlling for potential cofounders. Our study indicates that child maltreatment the affects children’s cognitive functionality beyond health and well-being.

Depressive Illnesses in Children and Adolescents: A Review of Current Concepts

1985 ◽  
Vol 30 (2) ◽  
pp. 119-129 ◽  
Author(s):  
B.J. Mcconville ◽  
R.T. Bruce
Keyword(s):  
Children And Adolescents ◽  
Current Knowledge ◽  
Considerable Progress ◽  
Childhood And Adolescence ◽  
Age Related ◽  
Developmental Age ◽  
The Subject ◽  
Made In

Considerable progress has been made in our understanding of depressive illnesses in childhood and adolescence, especially over the last several years. A number of major books on the subject have now appeared, along with a large number of individual papers. This paper attempts to summarize current knowledge, and indicates developmental, age-related and other issues which still require further study.

scholarly journals The Role of Cognitive Functioning in Medication Adherence of Children and Adolescents with HIV Infection

2008 ◽  
Vol 34 (2) ◽  
pp. 164-175 ◽  
Author(s):  
K. Malee ◽  
P. L. Williams ◽  
G. Montepiedra ◽  
S. Nichols ◽  
P. A. Sirois ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Hiv Infection ◽  
Cognitive Functioning ◽  
Children And Adolescents

Effects of active video games on children and adolescents: A systematic review with meta‐analysis

2019 ◽  
Vol 30 (1) ◽  
pp. 4-12 ◽  
Author(s):  
Crystian B. Oliveira ◽  
Rafael Z. Pinto ◽  
Bruna T. C. Saraiva ◽  
William R. Tebar ◽  
Leandro D. Delfino ◽  
...  
Keyword(s):  
Systematic Review ◽  
Video Games ◽  
Children And Adolescents ◽  
Meta Analysis ◽  
Active Video Games ◽  
Active Video

scholarly journals Child maltreatment, cognitive functions and the mediating role of mental health problems among maltreated children and adolescents in Uganda

2020 ◽  
Author(s):  
Herbert E Ainamani ◽  
Godfrey Z Rukundo ◽  
Timothy Nduhukire ◽  
Eunice Ndyareba ◽  
Tobias Hecker
Keyword(s):  
Mental Health ◽  
Working Memory ◽  
Child Maltreatment ◽  
Executive Functions ◽  
Cognitive Functioning ◽  
Children And Adolescents ◽  
Mental Health Problems ◽  
Depression Scale ◽  
Well Being ◽  
Health Problems

Abstract Background: Child maltreatment poses high risks to the mental health and cognitive functioning of children not only in childhood but also in later life. However, it remains unclear whether child maltreatment is directly associated with impaired cognitive functioning or whether this link is mediated by mental health problems. Our study aimed at examining this research question among children and adolescents in Uganda. Methods: A sample of 232 school-going children and adolescents with a mean age of 14.03 (SD = 3.25) was assessed on multiple forms of maltreatment using the Maltreatment and Abuse Chronology Exposure – Pediatric Version (pediMACE). Executive functions were assessed by the Tower of London task and working memory by the Corsi Block Tapping task, while mental health problems were assessed using the Child PTSD Symptom Scale for PTSD and the Center for Epidemiological Studies Depression Scale for Children (CES-DC).Results: In total, 232(100%) of the participant reported to have experienced at least one type of maltreatment in their lifetime ranging from having been intentionally pushed by an authority figure (89.7%, n = 208) to entering an object in the participant’s body (2.6%, n =6). We found a negative association between child maltreatment and executive functions (β = -0.487, p < .001) and working memory (β = -0.242, p = .001). Mental health problems did not mediate this relationship.Conclusions: Child maltreatment seems to be related to lower working memory and executive functioning of affected children and adolescents even after controlling for potential cofounders. Our study indicates that child maltreatment affects children’s cognitive functionality beyond health and well-being.

scholarly journals A assistência de enfermagem em crianças e adolescentes portadores de anemia falciforme

2012 ◽  
Vol 2 (5) ◽  
pp. 5 ◽  
Author(s):  
Aline Barbosa Soares ◽  
Débora Rita Gobbi ◽  
André Moreno Silva ◽  
Gisele Duarte da Silva ◽  
Isabel Cristina Gomes Leite de Siqueira ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Sickle Cell ◽  
Nursing Care ◽  
Sickle Cell Anemia ◽  
Childhood And Adolescence ◽  
Nursing Interventions ◽  
Crisis Prevention ◽  
Calidad De Vida ◽  
High Prevalence ◽  
Prevention And Treatment

Anemia Falciforme é uma doença autossômica recessiva com elevada prevalência e morbimortalidade no Brasil. Apresenta uma variedade de complicações que se manifestam de forma peculiar em cada paciente, principalmente na infância e na adolescência. Levantar os diagnósticos e intervenções de enfermagem mais relevantes às crianças e aos adolescentes portadores da doença para proporcionar uma melhor qualidade de vida. Realizou-se o levantamento bibliográfico sobre o tema nas bases de dados SciELO, LILACS e AAFESP, além de dados sobre mortalidade da doença no portal DATASUS. Em 2008, 38,6% das mortes por Anemia Falciforme no Brasil compreendeu a faixa etária entre 0 e 19 anos, evidenciando a necessidade de uma assistência de enfermagem específica, baseada na prevenção e no tratamento das principais complicações da doença. O preparo do enfermeiro é fundamental para individualizar essa assistência junto às crianças e adolescentes portadores da doença para que se obtenha sucesso na prevenção das crises e no tratamento para amenizar os sintomas.Descritores: Enfermagem, Anemia Falciforme, Crianças e Adolescentes. Nursing care in children and adolescents with sickle cell anemiaAbstract: Sickle cell anemia is an autosomal recessive disease with a high prevalence, morbidity and mortality in Brazil. Features a variety of complications that manifest in a peculiar way in each patient, especially in childhood and adolescence. Raise the diagnoses and nursing interventions most relevant to children and adolescents with the disease to provide a better quality of life. We carried out the literature on the subject in the databases SciELO, LILACS and AAFESP, plus data on mortality rates in DATASUS portal. In 2008, 38.6% of deaths from sickle cell disease in Brazil comprised the age group between 0 and 19 years, highlighting the need for specific nursing care based on prevention and treatment of major complications of the disease. The preparation of nurses is critical to individualize this intervention with children and adolescents with the disease in order to achieve success in crisis prevention and treatment to alleviate the symptoms.Descriptors: Nursing, Sickle Cell Anemia, Children and Adolescents. Enfermería de atención a la infancia y la adolescencia con anemia de células falciformesResumen: La anemia falciforme es una enfermedad autosómica recesiva, con una alta prevalencia, morbilidad y mortalidad en Brasil. Cuenta con una variedad de complicaciones que se manifiestan de una manera peculiar en cada paciente, especialmente en la infancia y la adolescencia. Elevar los diagnósticos e intervenciones de enfermería más relacionados con los niños y adolescentes con la enfermedad de proporcionar una mejor calidad de vida. Hemos llevado a cabo la literatura sobre el tema en la bases de datos SciELO, LILACS y AAFESP, además de datos sobre las tasas de mortalidad en DATASUS portal. En 2008, el 38,6% de las muertes por la enfermedad de células falciformes en Brasil comprende el grupo de edad entre 0 y 19 años, destacando la necesidad de cuidados de enfermería específicos basados en la prevención y tratamiento de las principales complicaciones de la enfermedad. La preparación de las enfermeras es fundamental para individualizar la intervención con niños y adolescentes que padecen la enfermedad con el fin de lograr el éxito en la prevención de crisis y el tratamiento para aliviar los síntomas.Descriptores: Enfermería, Anemia de Células Falciformes, la Niñez y la Adolescencia.

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