Incidence of Testicular Cancer in the United States, 1999-2004

2009 ◽  
Vol 4 (4) ◽  
pp. 353-360 ◽  
Author(s):  
Julie S. Townsend ◽  
Lisa C. Richardson ◽  
Robert R. German
Keyword(s):  
United States ◽  
Testicular Cancer ◽  
Alaska Native ◽  
Germ Cell Tumors ◽  
White Men ◽  
The United States ◽  
Incidence Rates ◽  
Testicular Germ Cell ◽  
Cancer Statistics ◽  
Hispanic White

Testicular cancer is rare but primarily affects young men. To characterize the current incidence of testicular cancer in the United States, U.S. Cancer Statistics data from 1999 through 2004 were examined. Age-adjusted (2000 U.S. standard) incidence rates were calculated for seminoma and nonseminoma testicular germ cell tumors (TGCTs). Hispanic men had the largest increase in incidence rates for nonseminomas, followed by non-Hispanic White men (annual percentage change of 3.2% and 1.9%, respectively, p < .05). Nonseminomas peaked at a younger age for Hispanic, American Indian/Alaska Native (AIAN), and Asian/Pacific Islander (API) men. Whereas 9.6% of TGCTs were diagnosed at a distant stage in non-Hispanic White men, more Hispanic (16.1%), Black (13.8%), AIAN (16.8%), and API (14.9%) men with TGCTs were diagnosed with distant stage. Monitoring incidence rates for rare cancers by race/ethnicity has improved with national population-based cancer registry coverage. Disparities in diagnosis stage have implications for effective treatment of TGCTs.

Incidence of testicular cancer in the United States from 1992 to 2009.

2013 ◽  
Vol 31 (6_suppl) ◽  
pp. 339-339 ◽  
Author(s):  
Manas Nigam ◽  
Brisa Aschebrook-Kilfoy ◽  
Sergey Shikanov ◽  
Scott E. Eggener
Keyword(s):  
United States ◽  
Testicular Cancer ◽  
White Men ◽  
The United States ◽  
Incidence Rates ◽  
The Us ◽  
Hispanic Men ◽  
Tumor Characteristic ◽  
Race Ethnicity ◽  
Hispanic White

339 Background: The incidence of testicular cancer (TC) increased in the US through 2003. However, little is known about these trends after 2003. We sought to determine trends in TC incidence based on race, ethnicity and tumor characteristics. Methods: TC incidence and tumor characteristic data from 1992-2009 were extracted from the Surveillance, Epidemiology, and End Results-13 (SEER) registry. Trends were determined using JoinPoint. Results: TC incidence in the US increased from 1992 (5.7/100,000) to 2009 (6.8/100,000) with annual percentage change (APC) of 1.1% (p < 0.001). TC rates were highest in non-Hispanic white men (1992: 7.5/100,000; 2009: 8.6/1000) followed by Hispanic men (1992: 4.0/100,000; 2009: 6.3/100,000) and lowest among non-Hispanic black men (1992: 0.7/100,000; 2009: 1.7/100,000). Significantly increasing incidence rates were observed in non-Hispanic white men (1.2%, p < 0.001) but most prominently among Hispanics, especially from 2002-2009 (5.6%, p < 0.01). A significant increase was observed for localized TC (1.21%, p < 0.001) and metastatic TC (1.43%, p < 0.01). Increased incidence occurred in localized tumors for non-Hispanic white men (1.56%, p <0.001), while Hispanic men experienced an increase in localized (2.6%, p < 0.001), regionalized (16.5% from 2002-09, p < 0.01), and distant (2.6%, p < 0.01) disease. Conclusions: Through 2009, testicular cancer incidence continues to increase in the United States, most notably among Hispanic men. [Table: see text]

Increasing Incidence of Testicular Germ Cell Tumors Among Black Men in the United States

2005 ◽  
Vol 23 (24) ◽  
pp. 5757-5761 ◽  
Author(s):  
Katherine A. McGlynn ◽  
Susan S. Devesa ◽  
Barry I. Graubard ◽  
Philip E. Castle
Keyword(s):  
United States ◽  
Germ Cell ◽  
Black Men ◽  
Germ Cell Tumors ◽  
White Men ◽  
The United States ◽  
Incidence Rates ◽  
Seer Program ◽  
Testicular Germ Cell Tumors ◽  
Testicular Germ Cell

Purpose There has been marked disparity in the incidence of testicular germ cell tumors (TGCT) among white and black men for a number of decades in the United States. Since at least the beginning of the Surveillance, Epidemiology, and End Results (SEER) Program in 1973, incidence rates among white men have been five times higher than rates among black men. In addition, rates among white men have been increasing, whereas rates among black men have remained stable. However, a recent examination of ethnic-specific rates suggested that the incidence among black men may have begun to change in the 1990s. Patients and Methods TGCT incidence data from nine registries of the SEER Program were analyzed for the years 1973 to 2001. Trends were examined separately for seminoma and nonseminoma. Results Analyses found that the incidence of TGCT began to increase among black men between the 1988 to 1992 and 1993 to 1997 periods. Before that time, incidence among black men had decreased by 14.8%. Between 1988 to 1992 and 1998 to 2001, however, the incidence increased by 100%, with the incidence of seminoma increasing twice as much (124.4%) as the incidence of nonseminoma (64.3%). Over the 29-year time period, there was no evidence of a change in the proportion of tumors diagnosed at earlier stages among black men. In contrast, the proportion of tumors diagnosed at localized stages significantly increased among white men. Conclusion The incidence of TGCT among black men has increased since 1988 to 1992. Although the reasons for this increase are unclear, screening and earlier diagnosis of TGCT do not seem to be factors.

Racial Differences Among Boys With Testicular Germ Cell Tumors in the United States

2008 ◽  
Vol 179 (5) ◽  
pp. 1961-1965 ◽  
Author(s):  
Thomas J. Walsh ◽  
Benjamin J. Davies ◽  
Mary S. Croughan ◽  
Peter R. Carroll ◽  
Paul J. Turek
Keyword(s):  
United States ◽  
Germ Cell ◽  
Racial Differences ◽  
Germ Cell Tumors ◽  
The United States ◽  
Testicular Germ Cell Tumors ◽  
Testicular Germ Cell

scholarly journals Trends in the incidence of testicular germ cell tumors in the United States

Cancer ◽  
2002 ◽  
Vol 97 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Katherine A. McGlynn ◽  
Susan S. Devesa ◽  
Alice J. Sigurdson ◽  
Linda M. Brown ◽  
Lilian Tsao ◽  
...  
Keyword(s):  
United States ◽  
Germ Cell ◽  
Germ Cell Tumors ◽  
The United States ◽  
Testicular Germ Cell Tumors ◽  
Testicular Germ Cell

scholarly journals Trends in the Incidence of Pancreatic Adenocarcinoma in All 50 United States Examined Through an Age-Period-Cohort Analysis

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Wilson L da Costa ◽  
Abiodun O Oluyomi ◽  
Aaron P Thrift
Keyword(s):  
United States ◽  
Pancreatic Ductal Adenocarcinoma ◽  
Cohort Analysis ◽  
The United States ◽  
Incidence Rates ◽  
Ductal Adenocarcinoma ◽  
Birth Cohorts ◽  
Men And Women ◽  
Cancer Statistics ◽  
Incidence Trends

Abstract Background Pancreatic ductal adenocarcinoma is a major contributor to cancer-related mortality in the United States. We aimed to investigate trends in incidence rates from all 50 states from 2001 to 2016, overall and by race, sex, and state and using age-period-cohort analyses. Methods Age-adjusted incidence rates and trends in adults aged 35 years and older were calculated using data from the US Cancer Statistics registry. We used joinpoint regression to compute annual percent changes (APC) and average annual percent changes. We also analyzed incidence trends by age groups and birth cohorts through age-period-cohort modeling. Results Age-standardized incidence rates increased by 1.23% (95% confidence interval [CI] = 0.92% to 1.54%) annually between 2001 and 2008 but were stable between 2008 and 2016 (APC = 0.11%, 95% CI = -0.13% to 0.35%). APCs and inflection points were no different for men and women. Rates increased statistically significantly among non-Hispanic whites (NHW) and non-Hispanic blacks between 2001 and 2007 and between 2001 and 2008, respectively, but, in later years, rates increased slowly among NHWs (APC = 0.36%, 95% CI = 0.12% to 0.60%), and were stable among non-Hispanic blacks (APC = -0.40%, 95% CI = -0.89% to 0.10%). The number of states with age-standardized incidence rates no less than 20.4 per 100 000 increased from 16 in 2001–2003 to 40 by 2015–2016. We found a strong birth cohort effect in both men and women and increasing rates among successive birth cohorts of NHWs. Conclusions The incidence of pancreatic ductal adenocarcinoma has consistently increased in the United States, albeit at slower rates recently. We observed notable increases among NHWs and in some states in the central and southern part of the country.

Testicular Cancer

2006 ◽  
Vol 4 (10) ◽  
pp. 1038 ◽  
Author(s):  
_ _
Keyword(s):  
United States ◽  
Testicular Cancer ◽  
Solid Tumor ◽  
Standard Therapy ◽  
Malignant Tumors ◽  
Germ Cell Tumors ◽  
The United States ◽  
The Past ◽  
Recent Version ◽  
Advanced Tumors

An estimated 8250 new cases of testicular cancer will be diagnosed in the United States in 2006, with germ cell tumors (GCTs) constituting 95% of the malignant tumors arising in the testes. Although GCTs are relatively uncommon tumors, they are the most common solid tumor in men between the ages of 15 and 34 years. The worldwide incidence of these tumors has more than doubled in the past 40 years. More than 90% of all patients diagnosed with GCTs are cured, including 70% to 80% of patients with advanced tumors who are treated with chemotherapy. Standard therapy has been established at essentially all stages of management and must be closely followed to ensure the potential for cure. For the most recent version of the guidelines, please visit NCCN.org

scholarly journals Recent trends in the incidence of testicular germ cell tumors in the United States

Andrology ◽  
2014 ◽  
Vol 3 (1) ◽  
pp. 13-18 ◽  
Author(s):  
A. A. Ghazarian ◽  
B. Trabert ◽  
S. S. Devesa ◽  
K. A. McGlynn
Keyword(s):  
United States ◽  
Germ Cell ◽  
Germ Cell Tumors ◽  
The United States ◽  
Testicular Germ Cell Tumors ◽  
Testicular Germ Cell ◽  
Recent Trends

Testicular Cancer

2017 ◽  
Author(s):  
Katherine A. McGlynn ◽  
Ewa Rajpert-De Meyts ◽  
Andreas Stang
Keyword(s):  
Testicular Cancer ◽  
Germ Cell ◽  
Germ Cell Tumors ◽  
Developed Countries ◽  
Mortality Rates ◽  
Incidence Rates ◽  
European Ancestry ◽  
Testicular Germ Cell Tumors ◽  
Testicular Germ Cell ◽  
Cancer Types

Testicular cancer is a rare cancer in the general population, but is the most common neoplasm among young men in many countries. It has one of the highest heritabilities of all cancer types. The vast majority of testicular cancers are germ cell tumors; thus the terms “testicular cancer” and “testicular germ cell tumors” (TGCTs) are often used interchangeably. Globally, the incidence of testicular cancer is highest among men of European ancestry and lowest among men of African and Asian ancestries. Incidence rates have been increasing in many countries since at least the mid-twentieth century. Mortality rates, however, have sharply declined in developed countries. While the reason for the decline in mortality rates is well known, reasons for the increase in incidence remain poorly understood. Accumulating evidence supports the hypothesis that most TGCTs are linked to disturbed development of the testes, beginning in utero, but fostered by postnatal events.

Melanoma risk in men with testicular germ cell tumors in the United States.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e15554-e15554
Author(s):  
Brandon David Bernard ◽  
Sarah C. Markt ◽  
Laurence Albiges ◽  
Rowan Miller ◽  
Clair Beard ◽  
...  
Keyword(s):  
United States ◽  
Germ Cell ◽  
Germ Cell Tumors ◽  
The United States ◽  
Testicular Germ Cell Tumors ◽  
Melanoma Risk ◽  
Testicular Germ Cell

Changes in Disparities in Estimated HIV Incidence Rates Among Black, Hispanic/Latino, and White Men Who Have Sex With Men (MSM) in the United States, 2010–2015

2019 ◽  
Vol 81 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Donna Hubbard McCree ◽  
Austin M. Williams ◽  
Harrell W. Chesson ◽  
Linda Beer ◽  
William L. Jeffries ◽  
...  
Keyword(s):  
United States ◽  
White Men ◽  
The United States ◽  
Incidence Rates ◽  
Hiv Incidence ◽  
Sex With Men
Sign in / Sign up

Export Citation Format

Share Document