scholarly journals Use of varenicline for smoking cessation treatment in UK primary care: an association rule mining analysis

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Yue Huang ◽  
Sarah Lewis ◽  
John Britton
2021 ◽  
Vol 31 (1) ◽  
Author(s):  
Daniel Kotz ◽  
Carolien van Rossem ◽  
Wolfgang Viechtbauer ◽  
Mark Spigt ◽  
Onno C. P. van Schayck

AbstractIn the context of smoking cessation treatment in primary care, identifying patients at the highest risk of relapse is relevant. We explored data from a primary care trial to assess the validity of two simple urges to smoke questions in predicting long-term relapse and their diagnostic value. Of 295 patients who received behavioural support and varenicline, 180 were abstinent at week 9. In this subgroup, we measured time spent with urges to smoke (TSU) and strength of urges to smoke (SUT; both scales 1 to 6 = highest). We used separate regression models with TSU or SUT as predictor and relapse from week 9–26 or week 9–52 as an outcome. We also calculated the sensitivity (SP), specificity and positive predictive values (PPV) of TSU and SUT in correctly identifying patients who relapsed at follow-up. The adjusted odds ratios (aOR) for predicting relapse from week 9–26 were 1.74 per point increase (95% CI = 1.05–2.89) for TSU and 1.59 (95% CI = 1.11–2.28) for SUT. The aORs for predicting relapse from week 9–52 were 2.41 (95% CI = 1.33–4.37) and 1.71 (95% CI = 1.14–2.56), respectively. Applying a cut-point of ≥3 on TSU resulted in SP = 97.1 and PPV = 70.0 in week 9–26, and SP = 98.8 and PPV = 90.0 in week 9–52. Applying a cut-point of ≥4 on SUT resulted in SP = 99.0 and PPV = 85.7 in week 9–26, and SP = 98.8 and PPV = 85.7 in week 9–52. Both TSU and SUT were valid predictors of long-term relapse in patients under smoking cessation treatment in primary care. These simple questions may be useful to implement in primary care.Trial registration: Dutch Trial Register (NTR3067).


2021 ◽  
pp. tobaccocontrol-2021-056522
Author(s):  
Dolly Baliunas ◽  
Peter Selby ◽  
Claire de Oliveira ◽  
Paul Kurdyak ◽  
Laura Rosella ◽  
...  

BackgroundNo research has assessed the individual-level impact of smoking cessation treatment delivered within a general primary care patient population on multiple forms of subsequent healthcare service use.ObjectiveWe aimed to compare the rate of outpatient visits, emergency department (ED) visits and hospitalisations during a 5-year follow-up period among smokers who had and had not accessed a smoking cessation treatment programme.MethodsThe study was a retrospective matched cohort study using linked demographic and administrative healthcare databases in Ontario, Canada. 9951 patients who accessed smoking cessation services between July 2011 and December 2012 were matched to a smoker who did not access services, obtained from the Canadian Community Health Survey, using a combination of hard matching and propensity score matching. Outcomes were rates of healthcare service use from index date (programme enrolment or survey response) to March 2017.ResultsAfter controlling for potential confounders, patients in the overall treatment cohort had modestly greater rates of the outcomes: outpatient visits (rate ratio (RR) 1.10, 95% CI: 1.06 to 1.14), ED visits (RR 1.08, 95% CI: 1.03 to 1.13) and hospitalisations (RR 1.09, 95% CI: 1.02 to 1.18). Effect modification of the association between smoking cessation treatment and healthcare service use by prevalent comorbidity was found for outpatient visits (p=0.006), and hospitalisations (p=0.050), but not ED visits.ConclusionsPatients who enrolled in smoking cessation treatment offered through primary care clinics in Ontario displayed a modest but significantly greater rate of outpatient visits, ED visits and hospitalisations over a 5-year follow-up period.


2006 ◽  
Vol 31 (3) ◽  
pp. 233-239 ◽  
Author(s):  
Robert A. Schnoll ◽  
Margaret Rukstalis ◽  
E. Paul Wileyto ◽  
Alexandra E. Shields

BMJ Open ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. e053075
Author(s):  
Scott Veldhuizen ◽  
Peter Selby ◽  
Benjamin Wong ◽  
Laurie Zawertailo

ObjectivesThe COVID-19 pandemic has changed patterns of smoking, other substance use and other health-related behaviours, leading to a virtualisation of non-urgent medical care. In this study, we examine associated changes in outcomes of smoking-cessation treatment.DesignObservational study.SettingData are drawn from 221 physician-led primary care practices participating in a smoking cessation program in Ontario, Canada.Participants43 509 patients (53% female), comprising 35 385 historical controls, 6109 people enrolled before the pandemic and followed up during it, and 1815 people enrolled after the pandemic began.InterventionNicotine-replacement therapy with counselling.Primary outcome measure7-day self-reported abstinence from cigarettes at a follow-up survey 6 months after entry.ResultsFor people followed up in the 6 months (6M) after the pandemic began, quit probability declined with date of enrolment. Predicted probabilities were 31.2% (95% CI 30.0% to 32.5%) for people enrolled in smoking cessation treatment 6 months prior to the emergency declaration and followed up immediately after the state of emergency was declared, and 24.1% (95% CI 22.1% to 26.2%) for those enrolled in treatment immediately before the emergency declaration and followed up 6M later (difference=−6.5%, 95% CI −9.0% to −3.9%). Seasonality and total treatment use did not explain this decline.ConclusionThe probability of successful smoking cessation following treatment fell during the pandemic, with the decline consistent with an effect of ‘exposure’ to the pandemic-era environment. As many changes happened simultaneously, specific causes cannot be identified; however, the possibility that virtual care has been less effective than in-person treatment should be explored.


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