scholarly journals PyConvU-Net: a lightweight and multiscale network for biomedical image segmentation

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Changyong Li ◽  
Yongxian Fan ◽  
Xiaodong Cai
Keyword(s):  
Image Segmentation ◽  
Deep Learning ◽  
State Of The Art ◽  
Experimental Results ◽  
Actual Situation ◽  
Controlled Experiments ◽  
Biomedical Image ◽  
Segmentation Methods ◽  
Art Performance

Abstract Background With the development of deep learning (DL), more and more methods based on deep learning are proposed and achieve state-of-the-art performance in biomedical image segmentation. However, these methods are usually complex and require the support of powerful computing resources. According to the actual situation, it is impractical that we use huge computing resources in clinical situations. Thus, it is significant to develop accurate DL based biomedical image segmentation methods which depend on resources-constraint computing. Results A lightweight and multiscale network called PyConvU-Net is proposed to potentially work with low-resources computing. Through strictly controlled experiments, PyConvU-Net predictions have a good performance on three biomedical image segmentation tasks with the fewest parameters. Conclusions Our experimental results preliminarily demonstrate the potential of proposed PyConvU-Net in biomedical image segmentation with resources-constraint computing.

scholarly journals Non-Local Context Encoder: Robust Biomedical Image Segmentation against Adversarial Attacks

2019 ◽  
Vol 33 ◽  
pp. 8417-8424 ◽  
Author(s):  
Xiang He ◽  
Sibei Yang ◽  
Guanbin Li ◽  
Haofeng Li ◽  
Huiyou Chang ◽  
...  
Keyword(s):  
Image Segmentation ◽  
State Of The Art ◽  
Contextual Information ◽  
Local Context ◽  
Deep Convolutional Neural Networks ◽  
Biomedical Image ◽  
Feature Representations ◽  
Segmentation Methods ◽  
Spatial Dependencies ◽  
Non Local

Recent progress in biomedical image segmentation based on deep convolutional neural networks (CNNs) has drawn much attention. However, its vulnerability towards adversarial samples cannot be overlooked. This paper is the first one that discovers that all the CNN-based state-of-the-art biomedical image segmentation models are sensitive to adversarial perturbations. This limits the deployment of these methods in safety-critical biomedical fields. In this paper, we discover that global spatial dependencies and global contextual information in a biomedical image can be exploited to defend against adversarial attacks. To this end, non-local context encoder (NLCE) is proposed to model short- and long-range spatial dependencies and encode global contexts for strengthening feature activations by channel-wise attention. The NLCE modules enhance the robustness and accuracy of the non-local context encoding network (NLCEN), which learns robust enhanced pyramid feature representations with NLCE modules, and then integrates the information across different levels. Experiments on both lung and skin lesion segmentation datasets have demonstrated that NLCEN outperforms any other state-of-the-art biomedical image segmentation methods against adversarial attacks. In addition, NLCE modules can be applied to improve the robustness of other CNN-based biomedical image segmentation methods.

scholarly journals Contour Detection for Fibre of Preserved Szechuan Pickle Based on Dilated Convolution

2019 ◽  
Vol 9 (13) ◽  
pp. 2684 ◽  
Author(s):  
Hongyang Li ◽  
Lizhuang Liu ◽  
Zhenqi Han ◽  
Dan Zhao
Keyword(s):  
Edge Detection ◽  
State Of The Art ◽  
Contour Detection ◽  
Experimental Results ◽  
Contour Method ◽  
Class Differences ◽  
Dilated Convolution ◽  
The Mean ◽  
Art Performance

Peeling fibre is an indispensable process in the production of preserved Szechuan pickle, the accuracy of which can significantly influence the quality of the products, and thus the contour method of fibre detection, as a core algorithm of the automatic peeling device, is studied. The fibre contour is a kind of non-salient contour, characterized by big intra-class differences and small inter-class differences, meaning that the feature of the contour is not discriminative. The method called dilated-holistically-nested edge detection (Dilated-HED) is proposed to detect the fibre contour, which is built based on the HED network and dilated convolution. The experimental results for our dataset show that the Pixel Accuracy (PA) is 99.52% and the Mean Intersection over Union (MIoU) is 49.99%, achieving state-of-the-art performance.

scholarly journals Biomedical Image Segmentation via Representative Annotation

2019 ◽  
Vol 33 ◽  
pp. 5901-5908 ◽  
Author(s):  
Hao Zheng ◽  
Lin Yang ◽  
Jianxu Chen ◽  
Jun Han ◽  
Yizhe Zhang ◽  
...  
Keyword(s):  
Image Segmentation ◽  
Deep Learning ◽  
Active Learning ◽  
Iterative Process ◽  
Image Data ◽  
Manual Annotation ◽  
Convolutional Network ◽  
Biomedical Image ◽  
Image Patches ◽  
Representative Image

Deep learning has been applied successfully to many biomedical image segmentation tasks. However, due to the diversity and complexity of biomedical image data, manual annotation for training common deep learning models is very timeconsuming and labor-intensive, especially because normally only biomedical experts can annotate image data well. Human experts are often involved in a long and iterative process of annotation, as in active learning type annotation schemes. In this paper, we propose representative annotation (RA), a new deep learning framework for reducing annotation effort in biomedical image segmentation. RA uses unsupervised networks for feature extraction and selects representative image patches for annotation in the latent space of learned feature descriptors, which implicitly characterizes the underlying data while minimizing redundancy. A fully convolutional network (FCN) is then trained using the annotated selected image patches for image segmentation. Our RA scheme offers three compelling advantages: (1) It leverages the ability of deep neural networks to learn better representations of image data; (2) it performs one-shot selection for manual annotation and frees annotators from the iterative process of common active learning based annotation schemes; (3) it can be deployed to 3D images with simple extensions. We evaluate our RA approach using three datasets (two 2D and one 3D) and show our framework yields competitive segmentation results comparing with state-of-the-art methods.

Ensemble-based deep meta learning for medical image segmentation

2021 ◽  
pp. 1-7
Author(s):  
Usman Ahmed ◽  
Jerry Chun-Wei Lin ◽  
Gautam Srivastava
Keyword(s):  
Image Segmentation ◽  
Deep Learning ◽  
Learning Algorithm ◽  
State Of The Art ◽  
Medical Image Segmentation ◽  
The State ◽  
Data Set ◽  
Deep Learning Algorithm ◽  
Meta Learning ◽  
Small Set

Deep learning methods have led to a state of the art medical applications, such as image classification and segmentation. The data-driven deep learning application can help stakeholders to collaborate. However, limited labelled data set limits the deep learning algorithm to generalize for one domain into another. To handle the problem, meta-learning helps to learn from a small set of data. We proposed a meta learning-based image segmentation model that combines the learning of the state-of-the-art model and then used it to achieve domain adoption and high accuracy. Also, we proposed a prepossessing algorithm to increase the usability of the segments part and remove noise from the new test image. The proposed model can achieve 0.94 precision and 0.92 recall. The ability to increase 3.3% among the state-of-the-art algorithms.

DDeep3M: Docker-powered deep learning for biomedical image segmentation

2020 ◽  
Vol 342 ◽  
pp. 108804
Author(s):  
Xinglong Wu ◽  
Shangbin Chen ◽  
Jin Huang ◽  
Anan Li ◽  
Rong Xiao ◽  
...  
Keyword(s):  
Image Segmentation ◽  
Deep Learning ◽  
Biomedical Image

scholarly journals A New Ensemble Learning Framework for 3D Biomedical Image Segmentation

2019 ◽  
Vol 33 ◽  
pp. 5909-5916 ◽  
Author(s):  
Hao Zheng ◽  
Yizhe Zhang ◽  
Lin Yang ◽  
Peixian Liang ◽  
Zhuo Zhao ◽  
...  
Keyword(s):  
Image Segmentation ◽  
Ensemble Learning ◽  
State Of The Art ◽  
3D Models ◽  
Superior Performance ◽  
3D Image ◽  
Convolutional Network ◽  
Biomedical Image ◽  
Learning Framework ◽  
2D And 3D

3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets. Yet, 2D and 3D models have their own strengths and weaknesses, and by unifying them together, one may be able to achieve more accurate results. In this paper, we propose a new ensemble learning framework for 3D biomedical image segmentation that combines the merits of 2D and 3D models. First, we develop a fully convolutional network based meta-learner to learn how to improve the results from 2D and 3D models (base-learners). Then, to minimize over-fitting for our sophisticated meta-learner, we devise a new training method that uses the results of the baselearners as multiple versions of “ground truths”. Furthermore, since our new meta-learner training scheme does not depend on manual annotation, it can utilize abundant unlabeled 3D image data to further improve the model. Extensive experiments on two public datasets (the HVSMR 2016 Challenge dataset and the mouse piriform cortex dataset) show that our approach is effective under fully-supervised, semisupervised, and transductive settings, and attains superior performance over state-of-the-art image segmentation methods.

scholarly journals A General System for Automatic Biomedical Image Segmentation Using Intensity Neighborhoods

2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
Cheng Chen ◽  
John A. Ozolek ◽  
Wei Wang ◽  
Gustavo K. Rohde
Keyword(s):  
Image Segmentation ◽  
Learning Strategy ◽  
General System ◽  
Training Data ◽  
Tissue Segmentation ◽  
Biomedical Image ◽  
Nuclei Segmentation ◽  
Segmentation Methods ◽  
Microscopy Images ◽  
Better Than

Image segmentation is important with applications to several problems in biology and medicine. While extensively researched, generally, current segmentation methods perform adequately in the applications for which they were designed, but often require extensive modifications or calibrations before being used in a different application. We describe an approach that, with few modifications, can be used in a variety of image segmentation problems. The approach is based on a supervised learning strategy that utilizes intensity neighborhoods to assign each pixel in a test image its correct class based on training data. We describe methods for modeling rotations and variations in scales as well as a subset selection for training the classifiers. We show that the performance of our approach in tissue segmentation tasks in magnetic resonance and histopathology microscopy images, as well as nuclei segmentation from fluorescence microscopy images, is similar to or better than several algorithms specifically designed for each of these applications.

scholarly journals Biomedical Concept Recognition Using Deep Neural Sequence Models

2019 ◽  
Author(s):  
Negacy D. Hailu ◽  
Michael Bada ◽  
Asmelash Teka Hadgu ◽  
Lawrence E. Hunter
Keyword(s):  
Deep Learning ◽  
Natural Language Processing ◽  
Natural Language ◽  
Machine Translation ◽  
Language Processing ◽  
State Of The Art ◽  
Conditional Random Field ◽  
Concept Recognition ◽  
Performance Improvements ◽  
Art Performance

AbstractBackgroundthe automated identification of mentions of ontological concepts in natural language texts is a central task in biomedical information extraction. Despite more than a decade of effort, performance in this task remains below the level necessary for many applications.Resultsrecently, applications of deep learning in natural language processing have demonstrated striking improvements over previously state-of-the-art performance in many related natural language processing tasks. Here we demonstrate similarly striking performance improvements in recognizing biomedical ontology concepts in full text journal articles using deep learning techniques originally developed for machine translation. For example, our best performing system improves the performance of the previous state-of-the-art in recognizing terms in the Gene Ontology Biological Process hierarchy, from a previous best F1 score of 0.40 to an F1 of 0.70, nearly halving the error rate. Nearly all other ontologies show similar performance improvements.ConclusionsA two-stage concept recognition system, which is a conditional random field model for span detection followed by a deep neural sequence model for normalization, improves the state-of-the-art performance for biomedical concept recognition. Treating the biomedical concept normalization task as a sequence-to-sequence mapping task similar to neural machine translation improves performance.

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