scholarly journals The first case of SMARCB1 (INI1) - deficient squamous cell carcinoma of the pleura: a case report

BMC Cancer ◽  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Kazushi Yoshida ◽  
Yutaka Fujiwara ◽  
Yasushi Goto ◽  
Takashi Kohno ◽  
Akihiko Yoshida ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
First Case

Pseudoangiosarcomatous squamous cell carcinoma: first case report on penis.

2020 ◽  
Author(s):  
Liseana de Oliveira Barbosa ◽  
José Osvaldo Barbosa Neto ◽  
Antônio Augusto Lima Teixera Junior ◽  
Leudivan Ribeiro Nogueira ◽  
José de Ribamar Rodrigues Calixto ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Papilloma Virus ◽  
Squamous Cells ◽  
First Case ◽  
Macroscopic Findings ◽  
Atypical Keratinocytes ◽  
E6 Protein

Abstract Background: Pseudoangiosarcomatous squamous cell carcinoma, also called pseudovascular, pseudoangiomatoid or adenoid pseudovascular carcinoma, is an uncommon and highly aggressive variant of squamous cell carcinoma. Histologically, it is characterized by proliferation of atypical keratinocytes with acantholysis and formation of pseudovascular spaces, forming anastomosed channels lined with neoplastic cells that invade the dermis. These cells are positive for cytokeratin and vimentin and negative for vascular markers such as CD31 and CD34. There are few reports of this tumor variant in the literature. Skin, breast, lung and vulva involvement have been described. But to the best of our knowledge, no cases involving the penis have been described. This article aims to describe the first case of angiosarcomatous squamous cell carcinoma of the penis. Case Report: The patient presented with a painful lesion in the penis associated with urinary retention. Macroscopic findings exhibited an ulcerative vegetating lesion that involving the entire glans and part of the penile body, as well as infiltration of penile structures and scrotal skin. Microscopy shows atypical proliferation of sarcomatous keratinocyte pattern mimicking vascular spaces. These neoplastic squamous cells were positive for the cytokeratin marker and were negative for the CD31 and CD34 markers. Human papilloma virus biomarkers, p16, E6 protein and PCR, were all negative. Conclusion: This report presents the first reported case of penile pseudoangiosarcomatous squamous cell carcinoma, as an important differential diagnosis.

scholarly journals Primary squamous cell carcinoma of the peristomal skin of gastrostomy in a transplant patient: a first case report

2019 ◽  
Vol 10 (3) ◽  
pp. 573-576 ◽  
Author(s):  
Aurore Lailheugue ◽  
Jean-Baptiste Gibier ◽  
Guillaume Lassailly ◽  
Stéphanie Truant ◽  
François-René Pruvot ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Transplant Patient ◽  
Primary Squamous Cell Carcinoma ◽  
First Case ◽  
Peristomal Skin

Congenital duplication of the larynx

2014 ◽  
Vol 128 (6) ◽  
pp. 555-556 ◽  
Author(s):  
A I Simpson ◽  
A Khanna ◽  
A Stanton
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Incidental Finding ◽  
Vocal Folds ◽  
Academic Interest ◽  
Respiratory Airway ◽  
First Case ◽  
New Diagnosis

AbstractIntroduction:The larynx is an intricate structure serving three important functions in humans: it protects the lower respiratory airway, facilitates respiration and helps produce sound through a key role in phonation.Objective:We report the first published finding of congenital duplication of the larynx in a patient with previously cleared squamous cell carcinoma of the neck and a new diagnosis of squamous cell carcinoma of the lung.Case report:We describe the incidental finding of duplication of the larynx in a 62-year-old man with previously completely cleared squamous cell carcinoma of the neck, who presented with worsening dyspnoea. We also provide a brief overview of other published cases in which duplication of the vocal folds and epiglottis has been reported.Results:Our patient experienced no symptoms related to this incidental finding of congenital duplication of the larynx.Conclusion:The first case of congenital duplication of the larynx is currently of academic interest only; however, the possible association with squamous cell carcinoma is postulated to raise awareness in clinicians who may observe further cases in the future.

scholarly journals Primary Adrenal Squamous Cell Carcinoma in a Single Kidney Patient: Case Report and Review of Literature

2019 ◽  
Vol 120 (1) ◽  
pp. 24-29
Author(s):  
Mehdi Kardoust Parizi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Adrenal Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Left Kidney ◽  
Neuron Specific Enolase ◽  
Pathology Report ◽  
Positive Staining ◽  
First Case

The adrenal gland is a common metastatic site of squamous cell carcinoma (SCC), however primary adrenal SCC has not been reported in literature. In this case report, we presented the first case of primary adrenal SCC. A 53-year-old man presented with chronic right flank pain. Abdominopelvic computed tomography (CT) confirmed left kidney agenesis and a soft tissue density mass measuring about 40×30 mm in the right adrenal gland. Adrenal functional assessment including metanephrine, normetanephrine and vanillyl mandelic acid were normal. The patient underwent surgical resection of right adrenal mass. Pathology report revealed adrenal SCC. Immunohistochemistry evaluation demonstrated positive staining for P63, CK, CD10, CK7, chromogranin, neuron specific enolase, and negative staining for alpha-inhibin, neurofilament, CK20, and tyrosine hydroxylase that were compatible with SCC. All other assessments to find primary site of SCC including upper and lower gastro-intestinal endoscopy, chest CT scan, positron emission tomography scan, and bronchoscopy demonstrated normal findings. To our knowledge, this is the first case of primary adrenal SCC without any evidence of metastatic nature of such adrenal involvement by SCC.

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