scholarly journals The impact of obesity on surgical outcomes in patients undergoing emergency laparotomy for high-risk abdominal emergencies

BMC Surgery ◽  
2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Woubet Tefera Kassahun ◽  
Matthias Mehdorn ◽  
Jonas Babel

Abstract Background Obesity has been shown to increase the rates of morbidity and occasionally mortality in patients undergoing nonbariatric elective surgery. However, little is known about the impact of obesity on outcomes after surgery for high-risk abdominal emergencies. Methods A single-center retrospective evaluation of outcomes in high-risk abdominal emergency patients categorized by body mass index (BMI) was conducted. Patient demographics, comorbidities, and operative details were analyzed. Patients with normal weight (BMI 18.5–24.9) served as comparators. Multivariable linear and logistic regression analyses were performed to assess the impact of obesity on surgical outcomes. Results In total, 886 patients with BMI < 18.5 (underweight; n = 50), 18.5–24.9 (normal weight; n = 306), 25–29.9 (overweight; n = 336) and ≥ 30 (obese; n = 194) based on the World Health Organization (WHO) weight classification criteria met the inclusion criteria. Compared to normal-weight patients, patients with overweight and obesity were older and more likely to be male. The rates of comorbidity (100% vs 91.2%, p =  < 0.0001), morbidity (77.8% vs 65.6%, p = 0.003), and in-hospital mortality (44.8% vs 30.4%, p = 0.001) were all higher in patients with obesity than in normal-weight patients. Patients with obesity had an increased intensive care unit length of stay (ICU LOS) (13 days vs 9 days, p = 0.019) and hospital LOS (21.4 days vs 18.1 days, p = 0.081) and prolonged ventilation (39.1% vs 19.6%, p = 0.003). As BMI deviated from the normal range, the morbidity and mortality rates increased incrementally, with the highest morbidity (87.9%) and mortality (54.5%) rates observed in morbidly obese patients (BMI ≥ 40). Conclusions Patients with obesity were the most likely to have coexisting conditions, experience postoperative complications, and die during the first admission following EL for high-risk abdominal emergencies.

Background and objective: The increase in obesity amongst adolescents is one of the most important public health concerns in many countries, including the Kingdom of Bahrain. The objective of the current study was to measure the prevalence of overweight and obesity among Bahraini adolescents. This study will aid in a better understanding of the issue and in pursuing preventive measures and campaigns to alleviate the problem. Methods: The weight, height, and body mass index of 9057 Bahraini adolescents was obtained from the Ministry of Health via the nation-wide health electronic file—I-Seha. The final sample consisted of 8463 adolescents; of which 4687 and 3776 were female and males, respectively. References standards from the World Health Organization were used to qualify the adolescents into normal weight, underweight, overweight, obese, and morbidly obese. Results: The overall prevalence of overweight and obesity was 42.3%. Among females the prevalence of overweight and obesity was 21.5% and 20.8%, respectively, whereas in males. the prevalence was 18% and 24.3%, respectively. The lowest prevalence of overweight and obesity was among males aged 15 years (36.4%) and highest among males aged 12 years (47.4%). While in females the prevalence of overweight and obesity was lowest and highest amongst 15-year-olds (38.3%) and 12-year-olds (48.5%). Conclusion: The prevalence of overweight and obesity is high in adolescents in the Kingdom of Bahrain, especially in the younger age group. This increases the urgency to undertake measures to control the problem in the younger population, in order to reduce serious outcomes.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
K Giesinger ◽  
JM Giesinger ◽  
DF Hamilton ◽  
J Rechsteiner ◽  
A Ladurner

Abstract Background Total knee arthroplasty is known to successfully alleviate pain and improve function in endstage knee osteoarthritis. However, there is some controversy with regard to the influence of obesity on clinical benefits after TKA. The aim of this study was to investigate the impact of body mass index (BMI) on improvement in pain, function and general health status following total knee arthroplasty (TKA). Methods A single-centre retrospective analysis of primary TKAs performed between 2006 and 2016 was performed. Data were collected preoperatively and 12-month postoperatively using WOMAC score and EQ-5D. Longitudinal score change was compared across the BMI categories identified by the World Health Organization. Results Data from 1565 patients [mean age 69.1, 62.2% women] were accessed. Weight distribution was: 21.2% BMI < 25.0 kg/m2, 36.9% BMI 25.0–29.9 kg/m2, 27.0% BMI 30.0–34.9 kg/m2, 10.2% BMI 35.0–39.9 kg/m2, and 4.6% BMI ≥ 40.0 kg/m2. All outcome measures improved between preoperative and 12-month follow-up (p < 0.001). In pairwise comparisons against normal weight patients, patients with class I-II obesity showed larger improvement on the WOMAC function and total score. For WOMAC pain improvements were larger for all three obesity classes. Conclusions Post-operative improvement in joint-specific outcomes was larger in obese patients compared to normal weight patients. These findings suggest that obese patients may have the greatest benefits from TKA with regard to function and pain relief one year post-op. Well balanced treatment decisions should fully account for both: Higher benefits in terms of pain relief and function as well as increased potential risks and complications. Trial registration This trial has been registered with the ethics committee of Eastern Switzerland (EKOS; Project-ID: EKOS 2020–00,879)


Author(s):  
Liliana Catan ◽  
Elena Amaricai ◽  
Roxana Ramona Onofrei ◽  
Calin Marius Popoiu ◽  
Emil Radu Iacob ◽  
...  

We aimed to synthesise the results of previous studies addressing the impact of overweight and obesity on plantar pressure in children and adolescents. An electronic search of scientific literature was conducted using PubMed, Cochrane and Scopus database, with keywords: “plantar pressure” AND “children” AND “obesity”; “plantar pressure” AND “adolescents” AND “obesity”, “plantar pressure” AND “children” AND “overweight”, “plantar pressure” AND “adolescents” AND “overweight”. Twenty-two articles were included in the review and the following data were recorded: authors, publication year, type of technology (systems, software) for the determination of plantar pressure, study characteristics. Most of the articles used dynamic plantar pressure determination with only four using static plantar pressure measurement. Using ultrasonography with static plantar pressure determination, the correlation between structural and functional changes in the feet of obese children. In overweight and obese children and adolescents, important findings were recorded: higher contact area, increased maximum force beneath the lateral and medial forefoot, increased pressure–time integral beneath the midfoot and 2nd–5th metatarsal regions. Significantly increased foot axis angle and significantly flatter feet were observed in obese subjects in comparison to their normal-weight counterparts. The obese children presented increased midfoot fat pad thickness, with decreased sensitivity of the whole foot and midfoot.


2020 ◽  
pp. 1-8
Author(s):  
E Yorke ◽  
J Tetteh ◽  
Vincent Boima ◽  
AE Yawson

Abstract Objective: We examined BMI as a health risk factor for self-reported diabetes mellitus, angina, strokes and arthritis among older Ghanaians aged 50 years and above. Design: We analysed the individual-level data from the World Health Organization Study on global AGEing and adult health Ghana Wave 2 (2014/2015). The influence of BMI on self-reported chronic conditions including diabetes, angina, stroke and arthritis was examined. Setting: Households from all the administrative regions of Ghana. Participants: Included 3350 adults aged 50 years and older. Results: The prevalence of overweight and obesity among participants was 22·8 % (95 % CI 20·6, 25·2) and 13·2 %, respectively (95 % CI 11·5, 15·1). With respect to individual chronic conditions, arthritis emerged with the highest prevalence rate of 7·3 (95 % CI 5·3, 9·9), while the prevalence rate of diabetes, angina and stroke was 2·8 % (95 % CI 2·0, 3·9), 1·7 % (95 % CI 1·1, 2·6) and 1·3 % (95 % CI 1·0, 1·8), respectively. The risk of diabetes among overweight and obesity was over three and two times, respectively, higher compared with participants with normal weights. Overweight and obesity were significantly more than two and three times likely to experience angina, respectively, compared with participants with normal weight. Obesity significantly influences arthritis with approximately two times increased odds compared with normal weight participants. Conclusion: Prevalence of obesity and overweight in Ghana is high and increasing, which poses a health risk at the individual and population levels. Inter-sectorial and multidisciplinary measures in line with the national non-communicable disease policies aimed at curbing this trend are imperative.


2017 ◽  
Vol 88 (3-4) ◽  
pp. 237-243 ◽  
Author(s):  
Avivit Brener ◽  
Rachel Bello ◽  
Yael Lebenthal ◽  
Michal Yackobovitch-Gavan ◽  
Moshe Phillip ◽  
...  

Background: Childhood obesity is a major health concern. Excess adiposity during childhood affects growth and puberty. Our aim was to assess whether genetic adult height is compromised in adolescents with obesity. Methods: In a retrospective study of 190 obese patients followed at our Pediatric Endocrinology Institute, adult height and delta height (the difference between adult height and mid-parental height) were compared to those of 150 healthy age-matched normal-weight controls. Review of medical files yielded the relevant clinical and anthropometric data of patients, controls, and parents. Results: Of the 190 obese adolescents, 150 were morbidly obese. The median adult height of morbidly obese males was 174.3 cm, of obese males 174 cm, and of normal-weight males 176 cm (p = 0.025). Delta height of morbidly obese males was –0.5 cm, of obese males –0.8 cm, and of normal-weight males, 3 cm (p < 0.0001). The median adult height of morbidly obese females was 161.3 cm, of obese females 162.8 cm, and of normal-weight females 162 cm (p = 0.37). Delta height of morbidly obese females was –1.85 cm, of obese females –0.95 cm, and of normal-weight females 0.7 cm (p = 0.019). Impairment of potential genetic height was not associated with obesity-related comorbidities. Conclusion: Adolescents with obesity showed impairment of potential genetic adult height as compared to that of normal-weight subjects.


Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3102
Author(s):  
Jingqi Song ◽  
Ji Zhang ◽  
Wafaie Fawzi ◽  
Yangmu Huang

This study aimed to examine the impact of a wide range of demographic, socioeconomic, and community factors on the double burden of malnutrition among women of reproductive age using longitudinal data. We used data about 11,348 women of reproductive age who participated in the China Health and Nutrition Survey (CHNS), a longitudinal survey, between 1989 and 2015. Nutritional outcomes were categorized into four groups, namely underweight, normal weight, overweight, and obesity, with normal weight as reference. A multinomial logit model was fitted due to geographic clustering and repeated observations of individuals. The prevalence of underweight decreased over time from 1991 but has tended to rise again since 2004, while the prevalence of overweight/obesity continued to rise between 1991 and 2015. Improved individual factors, socioeconomic status, and community urbanization reduced the risk of underweight but elevated the risk of overweight and obesity. The medium levels, rather than the highest levels, of household income and community urbanization are associated with a higher risk of overweight and obesity. The notable increase in underweight prevalence is a cause for concern to be addressed along with efforts to curb the rising tide of overweight. In order to enhance the nutritional status of women of reproductive age, it is essential to improving the community environment, levels of education, and living environment from a wider context. Long-term and targeted plans are urgently needed for nutrition improvements among the different populations.


2017 ◽  
Vol 27 (3) ◽  
pp. 342 ◽  
Author(s):  
Marcelo De Maio Nascimento ◽  
Luiz Gabriel Dantas Pereira ◽  
Phillipe Ramon Nogueira Cordeiro ◽  
Luciana Márcia Gomes de Araújo

Introduction: The study of the nutritional status of the elderly deserves attention, since there is no consensus on the criteria for the evaluation of the Body Mass Index (BMI) of this population.Objective: To evaluate the nutritional status of elderly women practicing regular physical exercises, as well as to compare the World Health Organization (WHO) and Lipschitz criteria to the identification of health risk and to examine their agreement.Methods: Descriptive cross-sectional study with 76 elderly women in physical exercise groups in Petrolina-PE. The nutritional status was obtained by the calculation of BMI according to WHO and Lipschitz criteria. The analysis of Variance (ANOVA) was used to compare the variables, followed by Tukey post hoc. The Kappa statistic established the agreement between the BMI criteria, the Spearman coefficient determined the correlation between BMI and abdominal circumference (AC).Results: Elderly patients aged 60-79 years were classified as being overweight by WHO and eutrophic by Lipschitz. Octogenarian demonstrated eutrophy, according to the criterion of Lipschitz, WHO diverged for this group between thinness and eutrophy. There was a weak agreement between both criteria, Kappa (0.232, p = 0.002) and a strong correlation between BMI and CA (r = 0.722, p <0.001).Conclusion: There was a divergence between the WHO and Lipschitz criteria. The WHO proved to be more sensitive to identifying overweight and obesity and Lipschitz's normal weight and malnutrition. The CA measure was more competent to detect health risk, especially in elderly eutrophic women.


2017 ◽  
Vol 45 (9) ◽  
Author(s):  
Kelly-Ann Eastwood ◽  
Ciara Daly ◽  
Alyson Hunter ◽  
David McCance ◽  
Ian Young ◽  
...  

AbstractObjective:To examine the impact of maternal obesity on completion of fetal anomaly screening.Methods:A retrospective analysis of 500 anomaly scans (19+0–21+6 weeks) was included. Women were categorised according to the World Health Organisation (WHO) body mass index (BMI) classification: normal weight (18.50–24.99 kg/mResults:Image quality deteriorated as BMI increased and was significantly different across the BMI categories (P<0.001). Performance was poorest in imaging of the fetal chest and was significantly different across BMI categories (P<0.001). In obese class III, 33% of four-chamber cardiac views and 38% of outflow tract views were not obtained. In total, 119 women (23.6%) had an incomplete scan. In obese class III, 44.1% of scans were incomplete compared with 10.2% in the normal BMI category (P<0.001). Of 117 women attending for repeat scans, 78.6% were complete, 11.1% were incomplete, 6.8% were advised to re-attend and 3.4% were referred to Fetal Medicine.Conclusion:Maternal obesity has a significant impact on completion of fetal anomaly screening.


2019 ◽  
Vol 221 (12) ◽  
pp. 2026-2034 ◽  
Author(s):  
Martial L Ndeffo-Mbah ◽  
Abhishek Pandey

Abstract Background Yellow fever (YF) is a vector-borne viral hemorrhagic disease endemic in Africa and Latin America. In 2016, the World Health Organization (WHO) developed the Eliminate YF Epidemics strategy aiming at eliminating YF epidemics by 2026. Methods We developed a spatiotemporal model of YF, accounting for the impact of temperature, vector distribution, and socioeconomic factors on disease transmission. We validated our model against previous estimates of YF basic reproductive number (R0). We used the model to estimate global risk of YF outbreaks and vaccination efforts needed to achieve elimination of YF epidemics. Results We showed that the global risk of YF outbreaks is highly heterogeneous. High-risk transmission areas (R0 &gt; 6) are mainly found in West Africa and the Equatorial region of Latin America. We showed that vaccination coverage needed to eliminate YF epidemics in an endemic country varies substantially between districts. In many endemic countries, a 90% vaccination coverage is needed to achieve elimination. However, in some high-risk districts in Africa, a 95% coverage may be required. Conclusions Global elimination of YF epidemics requires higher population-level immunity than the 80% coverage recommended by the WHO. Optimal YF vaccination strategy should be tailored to the risk profile of each endemic country.


2020 ◽  
Vol 8 (2) ◽  
pp. e001529
Author(s):  
Thijs T W van Herpt ◽  
Symen Ligthart ◽  
Maarten J G Leening ◽  
Mandy van Hoek ◽  
Aloysius G Lieverse ◽  
...  

IntroductionPre-diabetes, a status conferring high risk of overt diabetes, is defined differently by the American Diabetes Association (ADA) and the WHO. We investigated the impact of applying definitions of pre-diabetes on lifetime risk of diabetes in women and men from the general population.Research design and methodsWe used data from 8844 women without diabetes and men aged ≥45 years from the prospective population-based Rotterdam Study in the Netherlands. In both gender groups, we calculated pre-diabetes prevalence according to ADA and WHO criteria and estimated the 10-year and lifetime risk to progress to overt diabetes with adjustment for competing risk of death.ResultsOut of 8844 individuals, pre-diabetes was identified in 3492 individuals (prevalence 40%, 95% CI 38% to 41%) according to ADA and 1382 individuals (prevalence 16%, 95% CI 15% to 16%) according to WHO criteria. In both women and men and each age category, ADA prevalence estimates doubled WHO-defined pre-diabetes. For women and men aged 45 years having ADA-defined pre-diabetes, the 10-year risk of diabetes was 14.2% (95% CI 6.0% to 22.5%) and 9.2% (95% CI 3.4% to 15.0%) compared with 23.2% (95% CI 6.8% to 39.6%) and 24.6% (95% CI 8.4% to 40.8%) in women and men with WHO-defined pre-diabetes. At age 45 years, the remaining lifetime risk to progress to overt diabetes was 57.5% (95% CI 51.8% to 63.2%) vs 80.2% (95% CI 74.1% to 86.3%) in women and 46.1% (95% CI 40.8% to 51.4%) vs 68.4% (95% CI 58.3% to 78.5%) in men with pre-diabetes according to ADA and WHO definitions, respectively.ConclusionPrevalence of pre-diabetes differed considerably in both women and men when applying ADA and WHO pre-diabetes definitions. Women with pre-diabetes had higher lifetime risk to progress to diabetes. The lifetime risk of diabetes was lower in women and men with ADA-defined pre-diabetes as compared with WHO. Improvement of pre-diabetes definition considering appropriate sex-specific and age-specific glycemic thresholds may lead to better identification of individuals at high risk of diabetes.


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