scholarly journals One year of laboratory-based COVID-19 surveillance system in Belgium: main indicators and performance of the laboratories (March 2020–21)

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Marjan Meurisse ◽  
Adrien Lajot ◽  
Yves Dupont ◽  
Marie Lesenfants ◽  
Sofieke Klamer ◽  
...  
Keyword(s):  
Surveillance System ◽  
National Laboratory ◽  
First Year ◽  
Positivity Ratio ◽  
And Performance ◽  
Set Up ◽  
One Year ◽  
High Level ◽  
The Impact ◽  
Epidemiological Situation

Abstract Background With the spread of coronavirus disease 2019 (COVID-19), an existing national laboratory-based surveillance system was adapted to daily monitor the epidemiological situation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Belgium by following the number of confirmed SARS-CoV-2 infections, the number of performed tests and the positivity ratio. We present these main indicators of the surveillance over a one-year period as well as the impact of the performance of the laboratories, regarding speed of processing the samples and reporting results, for surveillance. Methods We describe the evolution of test capacity, testing strategy and the data collection methods during the first year of the epidemic in Belgium. Results Between the 1st of March 2020 and the 28th of February 2021, 9,487,470 tests and 773,078 COVID-19 laboratory confirmed cases were reported. Two epidemic waves occurred, with a peak in April and October 2020. The capacity and performance of the laboratories improved continuously during 2020 resulting in a high level performance. Since the end of November 2020 90 to 95% of the test results are reported at the latest the day after sampling was performed. Conclusions Thanks to the effort of all laboratories a performant exhaustive national laboratory-based surveillance system to monitor the epidemiological situation of SARS-CoV-2 was set up in Belgium in 2020. On top of expanding the number of laboratories performing diagnostics and significantly increasing the test capacity in Belgium, turnaround times between sampling and testing as well as reporting were optimized over the first year of this pandemic.

scholarly journals One Year of Laboratory Based COVID-19 Surveillance System in Belgium: Main Indicators and Performance of the Laboratories

2021 ◽  
Author(s):  
Marjan Meurisse ◽  
Adrien Lajot ◽  
Yves Dupont ◽  
Marie Lesenfants ◽  
Sofieke Klamer ◽  
...  
Keyword(s):  
Surveillance System ◽  
National Laboratory ◽  
First Year ◽  
Positivity Ratio ◽  
And Performance ◽  
Set Up ◽  
One Year ◽  
High Level ◽  
The Impact ◽  
Epidemiological Situation

Abstract Background: With the spread of coronavirus disease 2019 (COVID-19), an existing national laboratory based surveillance system was adapted to daily monitor the epidemiological situation of SARS-CoV-2 in the Belgium by following the number of confirmed COVID-19 infections, the number of performed tests and the positivity ratio. We present these main indicators of the surveillance over a one-year period as well as the impact of the performance of the laboratories, regarding speed of processing the samples and reporting results, for surveillance.Methods: We describe the evolution of test capacity, testing strategy and the data collection methods during the first year of the epidemic in Belgium.Results: Between the 1th of March 2020 and the 28th of February 2021, 9,487,470 tests and 773,078 COVID-19 laboratory confirmed cases were reported. Two epidemic waves occurred, with a peak in April and October 2020. The capacity and performance of the laboratories improved continuously during 2020 resulting in a high level performance. Since the end of November 2020 90 to 95% of test results are reported at the latest the day after sampling was performed.Conclusions: Thanks to the effort of all laboratories a performant exhaustive national laboratory based surveillance system to monitor the epidemiological situation of SARS-CoV-2 was set up in Belgium in 2020. On top of expanding the number of laboratories performing diagnostics and significantly increasing the test capacity in Belgium, turnaround times between sampling and testing as well as reporting were optimized over the first year of this pandemic.

Couples Facing the Birth of a Newborn with a Congenital Anomaly: PTSD Symptoms in the First Year

2018 ◽  
Vol 35 (12) ◽  
pp. 1168-1172 ◽  
Author(s):  
Francesca Bevilacqua ◽  
Francesco Morini ◽  
Antonio Zaccara ◽  
Chiara De Marchis ◽  
Annabella Braguglia ◽  
...  
Keyword(s):  
First Year ◽  
Stressful Situation ◽  
Ptsd Symptoms ◽  
Impact Of Event Scale ◽  
Event Scale ◽  
Stress Symptoms ◽  
Parental Gender ◽  
Set Up ◽  
The Impact

Objective The objective of this study was to assess the presence of posttraumatic stress disorder (PTSD) symptoms in parental couples of newborn requiring early surgery at 6 and 12 months after birth. Study Design A longitudinal study was set up from January 2014 to June 2015. As a measure of PTSD, we used the Italian version of the Impact of Event Scale—Revised (IES-R). Results Thirty-four couples form the object of the study. At 6 months, half of mothers (52.9%) and fathers (44.1%) reported traumatic stress symptoms above the clinical cutoff. Percentages remained stable at 12 months. When parental gender and length of follow-up were compared with two-factor analysis of variance, none had an impact on IES-R score, nor an interaction between these factors was found. A significant correlation of IES-R total score was present within the couple both at 6 and 12 months (6 months—r: 0.6842, p < 0.0001 and 12 months—r: 0.4045, p = 0.0177). Conclusion Having a child with a repaired malformation represents a complex prolonged stressful situation with persistent burden for both parents who are at high risk of developing PTSD symptoms.

High Resolution Large Eddy Simulations to Evaluate Turbulence Properties Within a Real Helicopter Engine Combustor

2018 ◽  
Author(s):  
Charlie Koupper ◽  
Jean Lamouroux ◽  
Stephane Richard ◽  
Gabriel Staffelbach
Keyword(s):  
Gas Turbine ◽  
Turbulence Intensity ◽  
Numerical Scheme ◽  
Mesh Refinement ◽  
Large Eddy Simulations ◽  
Scale Model ◽  
Large Eddy ◽  
Set Up ◽  
High Level ◽  
The Impact

In a gas turbine, the combustor is feeding the turbine with hot gases at a high level of turbulence which in turns strongly enhances the heat transfer in the turbine. It is thus of primary importance to properly characterize the turbulence properties found at the exit of a combustor to design the turbine at its real thermal constraint. This being said, real engine measurements of turbulence are extremely rare if not inexistent because of the harsh environment and difficulty to implement experimental techniques that usually operate at isothermal conditions (e.g. hot wire anemometry). As a counterpart, high fidelity unsteady numerical simulations using Large Eddy Simulations (LES) are now mature enough to simulate combustion processes and turbulence within gas turbine combustors. It is thus proposed here to assess the LES methodology to qualify turbulence within a real helicopter engine combustor operating at take-off conditions. In LES, the development of turbulence is primarily driven by the level of real viscosity in the calculation, which is the sum of three contributions: laminar (temperature linked), turbulent (generated by the sub-grid scale model) and artificial (numerics dependent). In this study, the impact of the two main sources of un-desired viscosity is investigated: the mesh refinement and numerical scheme. To do so, three grids containing 11, 33 and 220 million cells for a periodic sector of the combustor are tested as well as centred second (Lax-Wendroff) and third order (TTGC) in space schemes. The turbulence properties (intensity and integral scales) are evaluated based on highly sampled instantaneous solutions and compared between the available simulations. Results show first that the duration of the simulation is important to properly capture the level of turbulence. If short simulations (a few combustor through-times) may be sufficient to evaluate the turbulence intensity, a bias up to 14% is introduced for the turbulence length scales. In terms of calculation set-up, the mesh refinement is found to have a limited influence on the turbulence properties. The numerical scheme influence on the quantities studied here is small, highlighting that the employed schemes dissipation properties are already sufficient for turbulence characterization. Finally, spatially averaged values of turbulence intensity and lengthscale at the combustor exit are almost identically predicted in all cases. However, significant variations from hub to tip are reported, which questions the pertinence to use 0-D turbulence boundary conditions for turbines. Based on the set of simulations discussed in the paper, guidelines can be derived to adequately set-up (mesh, scheme) and run (duration, acquisition frequency) a LES when turbulence evaluation is concerned. As no experimental counterpart to this study is available, the conclusions mainly aim at knowing the possible numerical bias rather than commenting on the predictivity of the approach.

Ethical Considerations and Practical Implications in Romanian Covid-19 Vaccination Campaign

2021 ◽  
Vol 66 (Special Issue) ◽  
pp. 156-157
Author(s):  
Petru Sandu ◽  
◽  
Maria Aluaș ◽  
Răzvan M. Cherecheș ◽  
◽  
...  
Keyword(s):  
Public Health ◽  
Vaccination Campaign ◽  
European Countries ◽  
Ethical Considerations ◽  
Vaccination Rates ◽  
One Year ◽  
High Level ◽  
Vaccination Campaigns ◽  
The Impact ◽  
Practical Implications

"Besides its undoubtable significant contribution to morbidity and mortality worldwide, the COVID-19 pandemic has had numerous political, social, economic, and public health implications. Vaccination, an already long debated public health ethics theme, has reoccurred in force, as the efforts of the scientific community to curb the pandemic resulted in a viable vaccine less than one year since COVID-19 was declared a pandemic. High-level, international negotiations dictated states’ COVID-19 vaccine availability in the first few months, therefore each national Government had to develop and deploy vaccination campaigns prioritizing certain population categories. This paper aims to present Romanian COVID-19 vaccination campaign, from its inception to the present days, by focusing on the ethical considerations (e.g. prioritization, coercion, non-discrimination) and their practical implications ( e.g. vaccination hesitancy, rates, fake news). Like most countries in the European Community, Romania has initially adopted a Rawlsian approach to vaccination, prioritizing the older adults and the individuals with chronic conditions. However, unlike other European countries, coercion was not considered in any form (e.g. extended mobility facilities for the vaccinated), more recently incentives such as food vouchers being discussed. The impact of these decisions on the vaccination rates and hesitancy are discussed in the context of other European countries examples of vaccination campaigns. "

scholarly journals Timing of Susceptibility to Fusarium Head Blight in Winter Wheat

Plant Disease ◽  
2020 ◽  
Vol 104 (11) ◽  
pp. 2928-2939
Author(s):  
Christina Cowger ◽  
Giovanni Beccari ◽  
Yanhong Dong
Keyword(s):  
Winter Wheat ◽  
Fusarium Head Blight ◽  
Resistant Cultivar ◽  
First Year ◽  
Head Blight ◽  
Kernel Infection ◽  
Risk Forecasting ◽  
One Year ◽  
Moderately Resistant ◽  
The Impact

The duration of wheat susceptibility to Fusarium infection has implications for risk forecasting, fungicide timing, and the likelihood that visible kernel damage may underpredict deoxynivalenol (DON) contamination. A field experiment was conducted to explore the impact of varying infection timings on Fusarium head blight (FHB) development in winter wheat. Trials in four successive years (2010 to 2013) in North Carolina utilized one susceptible and one moderately resistant cultivar possessing similar maturity, stature, and grain quality. Inoculum was applied in the form of sprayed Fusarium graminearum conidia. In the first year, the nine infection timings were from 0 to 21 days after anthesis (daa), whereas in the following 3 years, they ranged from 0 to 13 daa. Infection progression was compared among inoculation timings by sampling spikes five to six times during grain-fill. Based on DON, percent kernel damage and kernel infection, and fungal spread as assayed via qPCR, the moderately resistant cultivar had at least a 2- to 3-day shorter window of susceptibility to damaging FHB infection than the susceptible cultivar. The results suggest that duration of susceptibility is an important aspect of cultivar resistance to FHB. In 2012, the window of susceptibility for both cultivars was extended by cold snaps during anthesis. After debranning in one year, the majority of DON was found to be in the bran fraction of kernels; there was also a trend for later infections to lead to a higher percentage of DON in the nonbran fraction, as well as a higher ratio of DON to FDK.

scholarly journals Impact of Component Dispersion in DC to DC Low-Power Low-Voltage Power Converter Array

Electronics ◽  
2019 ◽  
Vol 8 (9) ◽  
pp. 917
Author(s):  
Jean-Christophe CREBIER ◽  
Theo LAMORELLE ◽  
Silvain MARACHE ◽  
Thanh Hai PHUNG ◽  
Van-Sang NGUYEN ◽  
...  
Keyword(s):  
Closed Loop ◽  
Low Voltage ◽  
Power Converter ◽  
Point Of View ◽  
Statistical Point ◽  
Loop Control ◽  
In Series ◽  
And Performance ◽  
Set Up ◽  
The Impact

The paper deals with arrays of numerous power conversion cells, associated in series and/or in parallel to build larger step up or step down direct current (DC)/DC isolated converters. The work focuses on the impact of the spread and distribution of the conversion cell characteristics on the characteristics and performance of the power converter array (PCA). Based on a characterization protocol, about 130 conversion standard cells (CSC) are characterized and classified from a statistical point of view. Three families are defined and representatives are chosen and implemented in various configurations, in open and closed loop control, to analyze the impact of their spread characteristic over the global converter, the PCA. The paper is based on an extended practical set up and protocols, all described in details. Guidelines on CSCs implementation with respect to their dispersion are provided at the end on the paper.

The Art of Teaching: A Technique for Solving Simple “Set Up” Equations in One Unknown

1946 ◽  
Vol 39 (1) ◽  
pp. 35-38
Author(s):  
May L. Wilt
Keyword(s):  
First Year ◽  
Teaching Techniques ◽  
Simple Set ◽  
Starting Point ◽  
Ability Groups ◽  
Good Starting Point ◽  
Art Of Teaching ◽  
Set Up ◽  
One Year

No longer can teachers of mathematics be satisfied with the type of teaching that produces uncertain results. The first year of algebra is a good starting point for developing teaching techniques. Most children, who have had one year of algebra, can solve simple “set up” equations in one unknown if they are directed “what to do next.” They should be able to know “what to do next.” Very bright children find out for themselves, but the average and slower ability groups must be helped to develop a technique that will produce certainty and accuracy in results.

Examining the Impact of the SDLMI and Whose Future Is It? Over a Two-Year Period With Students With Intellectual Disability

2020 ◽  
Vol 125 (3) ◽  
pp. 217-229 ◽  
Author(s):  
Karrie A. Shogren ◽  
Tyler A. Hicks ◽  
Kathryn M. Burke ◽  
Anthony Antosh ◽  
Terri LaPlante ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Outcome Data ◽  
Future Research ◽  
First Year ◽  
Opposite Pattern ◽  
Nonlinear Growth ◽  
Intensive Intervention ◽  
Cluster Randomized ◽  
One Year ◽  
The Impact

Abstract The purpose of this study was to examine self-determination outcome data in the year following a one-year cluster randomized controlled trial (C-RCT) comparing the impacts of a Self-Determined Learning Model of Instruction (SDLMI) only condition to a SDLMI + Whose Future Is It? (SDLMI + WF) condition. Using multilevel B-spline model analysis with Bayesian estimation, we examined ongoing patterns of growth after the trial ended and all students were exposed to SDLMI + WF. The findings suggest that the inclusion of an additional year of outcome data provided additional insight into the impact of more intensive intervention conditions over time. Specifically, after the initial year of implementation, the SDLMI + WF condition predicted greater annual gains than the SDLMI only condition, unlike findings in the first year which reflected the opposite pattern. This evidence suggests a nonlinear growth pattern over multiple years of intervention with more intensive interventions. Implications for future research and practice are discussed.

scholarly journals Thermal Aspects of Safety Analysis for Shipment of West Valley Melter

2017 ◽  
Author(s):  
James E. Laurinat ◽  
Matthew R. Kesterson ◽  
Jeffery L. England ◽  
Edward T. Ketusky ◽  
Charles A. McKeel ◽  
...  
Keyword(s):  
National Laboratory ◽  
Safety Analysis ◽  
Department Of Energy ◽  
Savannah River ◽  
The West ◽  
Heating Source ◽  
Savannah River National Laboratory ◽  
Set Up ◽  
High Level ◽  
Cellular Concrete

The thermal aspects of a safety analysis for shipment of the West Valley melter are presented. The West Valley melter was used from 1996 to 2002 to vitrify regionally sourced high level radioactive waste. The U.S. Department of Energy (DOE) set up the West Valley Demonstration Project to encase this melter and grout it in low density cellular concrete, for disposal. DOE-West Valley requested the Savannah River National Laboratory to prepare a Safety Analysis Report. The thermal portion of the safety analysis covers Normal Conditions of Transport (NCT) and Hypothetical Accidents Conditions (HAC), as defined in the Code of Federal Regulations. For NCT, it is assumed that the encased melter is stored in either shade or direct sunlight at an ambient temperature of 311 K (100 °F). The defining HAC is exposure to a 1075 K (1475 °F) fire for 30 minutes. Finite element computer models were used to compute temperature profiles for NCT and HAC, given the thermal properties of the melter and its contents and tabulated radiolytic heating source concentrations. The resulting temperature conditions were used to estimate the pressurization due to evaporation of water from the concrete. The maximum calculated gauge pressures were determined to be 81 kPa (12 psig) for NCT and 580 kPa (84 psig) for HAC.

How Long Does an Economic Impact Last? Tracking the Impact of a New Giant Panda Attraction at an Australian Zoo

2016 ◽  
Vol 56 (5) ◽  
pp. 613-624 ◽  
Author(s):  
Sally Driml ◽  
Roy Ballantyne ◽  
Jan Packer
Keyword(s):  
Economic Impact ◽  
Impact Analysis ◽  
Investment Decision ◽  
Economic Benefits ◽  
First Year ◽  
Giant Pandas ◽  
Economic Impact Analysis ◽  
One Year ◽  
Tourism Attractions ◽  
The Impact

A concerning issue with Economic Impact Analysis (EIA) is that many EIAs give results for one year, without being explicit about how long impacts are expected to last. New tourism attractions should not be assumed to provide continuing positive impacts into the future. For instance, the Giant Pandas at Adelaide Zoo generated a positive economic impact in their first year of residence (22% of a sample of tourists visited Adelaide “due to pandas,” additional tourism expenditure in the region was $27.7 million, with $2.3 to $4.6 million captured by the zoo); however, increased numbers visiting to see the pandas lasted only two years. Investment decision makers expected larger, longer-term economic benefits than eventuated, and the zoo experienced financial difficulties. This study provides advice for predictive EIA of new tourism attractions and prompts a call for tourism EIA studies to be explicit about the time period for which results are relevant.

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