Retinal autofluorescence findings after COVID-19

AbstractThe main purpose of this study was to investigate the presence of retinal autofluorescence findings in COVID-19 patients. Observational study conducted in São Paulo in 2020. Demographic, medical history, and concomitant events, as well as medications used, hospitalization details, and laboratory test results, were obtained. Patients underwent eye examination and multimodal imaging, including color, red-free, autofluorescence fundus photography and optical coherence tomography. Eighteen patients had autofluorescence findings (6 females; average age 54 years, range 31 to 86 years; 26 eyes). Hyper-autofluorescence findings were present in 6 patients, Hypo-autofluorescence in 14 patients, and 6 patients had mixed pattern lesions. Retinal autofluorescence abnormalities were present in COVID-19 patients and may be secondary to primary or secondary changes caused by the SARS-CoV-2.

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Comparative Analysis of Anxiety/Depression Scores in COVID-19 Patients with Disease Severity, Sleep Patterns, and Certain Laboratory Test Results

Archives of Medical Science ◽

10.5114/aoms/136111 ◽

2021 ◽

Author(s):

Zi-Qiang Meng ◽

Qi Leng ◽

Xu Wang ◽

Chun-Hai Xu ◽

Jing Xu ◽

...

Keyword(s):

Laboratory Test ◽

Medical History ◽

Disease Severity ◽

Depression Scale ◽

Anxiety And Depression ◽

Test Results ◽

Past Medical History ◽

Hospital Anxiety ◽

Laboratory Test Results ◽

Lung Infections

IntroductionCoronavirus disease 2019 (COVID-19) is associated with severe emotional changes. This research aims to investigate the prevalence of anxiety and depression in COVID-19 patients and its relationship with disease severity, sleep patterns, lifestyle, and specific laboratory test results.Material and methodsAn observational study of 52 Chinese patients with COVID-19 was conducted to assess the relation between anxiety and depression (evaluated with the Hospital Anxiety and Depression Scale) and laboratory findings (lymphocytes, C-reactive proteins, leukocytes, alanine aminotransferase, aspartate aminotransferase). The relationships between the severity of COVID-19 in patients, the Insomnia Severity Index (ISI) score, and the Hospital Anxiety and Depression Scale (HADS) score were also investigated.ResultsThere was a significant statistical difference between the disease, smoking, and HADS-A scores (P = 0.011 / 0.020). The HADS-D score of patients with the disease was higher than in those without the past medical history (P = 0.008). The difference in C-reactive protein (CRP) between different lung infections, the HADS-A and HADS-D scores between different ages and ISI groups, and the correlation between the two scores were statistically significant.ConclusionsAnxiety and depression are associated with poor sleep quality, smoking, and past medical history in patients with COVID-19. Additionally, anxiety and depression were seen to coexist, and there was a positive correlation between them. Further, the inflammatory index CRP was significantly increased in bilateral lung infections.

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