A risk-based approach to validation of ion chromatography methods using suppressed conductivity
Keyword(s):
AbstractIon chromatography (IC) has evolved into one of the most widely used separation techniques of analytical chemistry. Consequently, the number of users of this method is continuously growing. Analysts often assume that widely used guidelines for HPLC method validation in regulated environments routinely apply to IC. This manuscript provides an analysis of the potential shortcomings of traditional approaches to development and validation of IC methods using suppressed conductivity detection and a risk-based alternative approach to these activities. The goal of the alternative approach is a reduction in the risk of erroneous determinations of analytes when IC methods using suppressed conductivity detection are employed.
2004 ◽
Vol 36
(3)
◽
pp. 517-524
◽
2002 ◽
Vol 957
(2)
◽
pp. 99-109
◽
2001 ◽
Vol 920
(1-2)
◽
pp. 333-344
◽
2019 ◽
Vol 91
(21)
◽
pp. 13824-13830
◽
2007 ◽
Vol 1155
(1)
◽
pp. 22-30
◽
2008 ◽
Vol 1192
(1)
◽
pp. 187-190
◽