scholarly journals Association of COVID-19 infection with large thrombi in left and right atrial appendages

2021 ◽  
Vol 73 (1) ◽  
Author(s):  
Saeed Ghodsi ◽  
Sara Taghi ◽  
Zahra Alizadeh-Sani ◽  
Yaser Jenab ◽  
Zahra Hosseini ◽  
...  

Abstract Background Multiple intra-atrial thrombi are found rarely except in the presence of prosthetic valves, intra-cardiac devices, structural connections like foramen ovale and thrombophilia. Case presentation We reported acute thrombosis formation in right and left atrial appendages of a 66-year old man admitted due to progressive dyspnea since 7 days earlier. He had a history of prior laryngeal Squamous Cell Carcinoma, apical hypertrophic cardiomyopathy (HCM), and atrial fibrillation (AF). Infection with COVID-19 was confirmed thereafter. Cardiac Magnetic Resonance Imaging (CMR) suggested the diagnosis of atrial clot superior to neoplasm. After surgical removal of the thrombi, symptoms as well as imaging features of pneumonia were resolved. Conclusions We should focus on different presentations and complications of systemic inflammation especially in the setting of COVID-19 infection. Although risk factors of thrombosis are present in some of these patients, rapid progression as well as unusual types of involvement may indicate to a new trigger.

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Monia Ghammam ◽  
Lobna Chouchane ◽  
Jihene Houas ◽  
Mouna Bellakhdher ◽  
Heyfa Bel Hadj Miled ◽  
...  

Abstract Background Pediatric neck masses are a common complaint in children. The most common etiologies include congenital lesions, lymphadenopathy, vascular malformations, inflammatory, and malignant lesions. Spontaneous sternocleidomastoid hematoma is exceptional in infant. Case presentation We describe a case of spontaneous cervical hematoma diagnosed in a 4-month-old child. Past history did not reveal a neck trauma, a history of difficult labor, a bleeding disorder or a pertinent family history. The diagnosis was suspected based on the imaging features and confirmed after surgical removal. Conclusions Sternocleidomastoid swelling is commonly encountered in infancy. Ultrasound still remains the initial modality of choice. The management modalities are controversial.


2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Suchita Mehta ◽  
Chadi Saifan ◽  
Marie Abdellah ◽  
Rita Choueiry ◽  
Rabih Nasr ◽  
...  

Background. Alport's syndrome is an X-linked hereditary disorder affecting the glomerular basement membrane associated with ocular and hearing defects. In women, the disease is much less severe compared to that in men. However, women with Alport's syndrome can have an accelerated form of their disease during pregnancy with worsening of kidney function and can also develop preeclampsia. There are only four described cases of Alport's syndrome in pregnancy.Case Presentation. 20-year-old woman with a history of Alport's syndrome, which during pregnancy worsened resulting in hypertension, proteinuria, and acute kidney injury. Fortunately, there was complete resolution of the proteinuria and kidney injury with delivery, and the patient did not require any renal replacement therapy.Conclusion. One of the four reported cases had an accelerated form of the disease during pregnancy with rapid progression of kidney injury and end-stage renal disease. There are no definite guidelines to monitor these patients during pregnancy. Further studies are required to understand the exact pathophysiology of kidney damage that occurs in pregnant women with Alport's syndrome. This may give us some insight into the prognostic predictors, so that we can monitor these women more thoroughly and prevent adverse outcomes.


2020 ◽  
Vol 13 (3) ◽  
pp. 1441-1445
Author(s):  
Mohammad Alrehaili ◽  
Emad Tashkandi

Colorectal cancer (CRC) is one of the most common malignancies in the world. It typically metastasizes to the lymph nodes, liver or lungs. Cardiac involvement is considered the least likely metastatic complication of malignant tumors including CRC. We report a rare case of metastatic rectal cancer to the liver, ovaries, lungs and peritoneum that presented initially with a 1-week history of rectal bleeding. Her hospital course was complicated by progressive dyspnea and palpitations secondary to right atrial metastasis based on imaging studies including cardiac MRI with contrast. The patient was not fit for chemotherapy or any surgical intervention given her poor prognosis and functional status in the setting of advanced stage of her disease. After discussion with the patient and her family, a decision was made to change her code status to DNR (do not resuscitate) and focus on palliative treatment of her disease. She expired about 2 weeks following her discharge date. Based on this case report, we recommend a high index of suspicion for cardiac metastasis when dealing with cardiac or respiratory complaints in cases of CRC that need careful evaluation with echocardiography and MRI.


1987 ◽  
Vol 32 (9) ◽  
pp. 785-787 ◽  
Author(s):  
M.L. Thurling

This is a case presentation of a 52 year old woman with a past history of schizophrenia who develops an acute psychosis. The point is emphasized that a deterioration in mental state in a patient with schizophrenia should not too readily be attributed to the functional’ psychosis. Psychiatric patients may present with organic mental disorders requiring medical or surgical intervention. Thus the psychiatrist must always be alert to the possibility of new pathology and examine carefully for signs of organic disturbances. This case turned out to be one of acute hyperparathyroidism cured by surgical removal of an adenoma of the parathyroid gland.


Author(s):  
Laiba Masood ◽  
Sana Sayeed ◽  
Samreen Aslam

Abstract Background Breast metastasis in hematological malignancies is a rare phenomenon, and it is primarily seen in acute myeloid leukemia (AML). In patients with acute lymphoblastic leukemia (ALL), this condition is even rarer. Case presentation. We present a case of a precursor B cell ALL involving breast in a 40-year-old female and its imaging features on mammography and ultrasound. Histopathology of core needle biopsy (CNB) specimen allowed us to diagnose ALL with extramedullary metastases. The patient was referred to oncology for further management. Conclusion To conclude, ALL infiltrating breast is rare but should be given due consideration, especially in the cases of known primary hematopoietic malignancy, particularly in patients presenting with a history of sudden lumps in the breast. A CNB can give reliable results in combination with flow cytometry and immunocytochemistry, circumventing the need for an excisional biopsy and allowing the commencement of early treatment.


Author(s):  
Mahnaz PejmanSani ◽  
Keivan GohariMoghadam ◽  
Mahbube Ebrahimpur

Introduction: Gaucher Disease is an autosomal recessive lysosomal storage disease. Pulmonary involvement in Gaucher Disease is rare and often seen in the severe form of the disease with the worst outcome. Case Presentation: A 30-year-old man and known case of Gaucher Disease presented to our clinic with history of progressive dyspnea since 8 months ago. Pulmonary function test showed restrictive pattern. Chest CT scan revealed diffuse bilateral interlobular septal thickening and small interstitial nodules with ground glass opacities in lower lobes. Conclusion: Patients with Gaucher Disease that present with progressive dyspnea may have a manifestation of interstitial or alveolar lung disease.


2021 ◽  
Vol 2 (6) ◽  
Author(s):  
Djoko Supriyandono ◽  
Marjono Dwi Wibowo

Background: Schwannoma is classified as a benign, encapsulated tumor, derived from the perineural cells which are classified as neural cell membranes. About 10% of Schwannomas has occurred in the head and neck and the incidence of Schwannoma arising from the Cervical C2 nerve roots is extremely rare. Aims of study: This case report aims to provide a rare case report on Schwannoma located in cervical cervices (C2& C3). Case presentation: A 37-year-old female patient with a lump in the left neck for 4 years ago, the first lump appeared as a larger (increasingly large 1×1 cm) marbles with no pain in the lump but over the past 4 months the patient felt his legs and arms are weak. Patients have a history of surgical removal of tumors in the back of the neckline by the end of 2016. At first, we estimated the lump that appeared on the left neck of the patient stands alone in the sense that it was not related to the history of the first lump surgery, but when further examination, the tumor was apparently related to the lump that appeared previously who had surgery. Conclusion: The extracranial Schwannoma in the head and neck areas is a rare neoplasm. The extracranial Schwannoma case is a case that is difficult to diagnose, in addition to good clinical examination, imaging examination, such as CT scan and MRI are an indispensable way of ensuring the diagnosis of an extracranial Schwannoma.


2020 ◽  
Author(s):  
Jin Tian ◽  
YaNan Xiao ◽  
TengLong Zhang ◽  
Jie Wang ◽  
CaiLong Jin ◽  
...  

Abstract Background: Pure testicular choriocarcinoma is very rare in clinic and the patient's age is 20-39 years (median age 29 years). Because of its polymorphic manifestations, it is not always suspected and patients are sometimes misdiagnosed. The case should be reported due to the rarity of the disease ,the onset age and the rapid progression of the disease. This case with primary lung cancer as the first diagnosis is a misdiagnosis. We hope we can provide some experience for clinical diagnosis and treatment. Case presentation: We report the case of a 46-year-old man who was admitted to our hospital with bloodshot sputum. Histopathological and immunohistochemical examination revealed pure choriocarcinoma. The patient had received radiotherapy, chemotherapy, immunotherapy, Over the next 5 months, the patient developed symptoms of multiple system metastases and died soon. Conclusions: Testicular choriocarcinoma is progressing rapidly. The clinical feature of choriocarcinoma is hemorrhaging at the metastatic site. Early diagnosis and timely treatment should be combined with the clinical manifestations and medical history of patients to strive for a longer survival time. We hope this case can provide guidance for the clinical diagnosis and treatment of the disease.


2017 ◽  
Vol 10 (1) ◽  
pp. 8-14 ◽  
Author(s):  
Meredith Barrett ◽  
Benjamin L. Viglianti ◽  
Christopher A. Hanson ◽  
Richard J. Schildhouse

As the fifth most common malignancy worldwide, hepatocellular carcinoma (HCC) is a frequently encountered clinical entity. Symptomatology associated with the diagnosis includes hepatic dysfunction and pain from capsular spread. Additionally, due to its propensity for vascular spread, extrahepatic intravascular involvement can also be seen. We present a unique case of intracardiac involvement of HCC. Originally diagnosed as acute on chronic heart failure, echocardiography revealed the symptom source – tumor obliteration of the right atrium. Clinical case presentation and management, along with radiographic images are presented. A review of the current literature highlights this uncommon presentation and the need for clinical suspicion of cardiac involvement in patients with a history of HCC presenting with heart failure.


2020 ◽  
Vol 5 (3 And 4) ◽  
pp. 155-160
Author(s):  
Mohsen Aghapoor ◽  
◽  
Babak Alijani Alijani ◽  
Mahsa Pakseresht-Mogharab ◽  
◽  
...  

Background and Importance: Spondylodiscitis is an inflammatory disease of the body of one or more vertebrae and intervertebral disc. The fungal etiology of this disease is rare, particularly in patients without immunodeficiency. Delay in diagnosis and treatment of this disease can lead to complications and even death. Case Presentation: A 63-year-old diabetic female patient, who had a history of spinal surgery and complaining radicular lumbar pain in both lower limbs with a probable diagnosis of spondylodiscitis, underwent partial L2 and complete L3 and L4 corpectomy and fusion. As a result of pathology from tissue biopsy specimen, Aspergillus fungi were observed. There was no evidence of immunodeficiency in the patient. The patient was treated with Itraconazole 100 mg twice a day for two months. Pain, neurological symptom, and laboratory tests improved. Conclusion: The debridement surgery coupled with antifungal drugs can lead to the best therapeutic results.


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