scholarly journals Predictive role of serum rheumatoid factor in different disease pattern of psoriasis and psoriatic arthritis

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Enas Zahran ◽  
Ali Youssof ◽  
Wafaa Shehata ◽  
Ahmed Bahgat ◽  
Emad Elshebiny
Keyword(s):  
Rheumatoid Factor ◽  
Signs And Symptoms ◽  
Inflammatory Disorder ◽  
Clinical Pattern ◽  
Positive Rheumatoid Factor ◽  
Disease Patterns ◽  
The Status ◽  
Disease Pattern ◽  
Variable Morphology ◽  
Genetic And Environmental Factors

Abstract Background Psoriasis is a multisystem inflammatory disorder with variable morphology, clinical pattern and multiple comorbidities. Interplay between genetic and environmental factors leading to an aberrant immune response in the skin may contribute to disease development. The assessment for risk factors, signs, and symptoms of potential comorbid diseases is an important component of patient management. The aim of this study is to determine rheumatoid factors (RF) positivity and its levels in psoriasis patients, and describe its relationship with the demographic and clinical characteristics, comorbidities, and disease patterns of psoriasis. Results Rheumatoid factor was positive in psoriatic patients more than control,30% of patients had positive rheumatoid factor while only 10% of control had positive results. Rheumatoid factor level was 63.8 ± 186.7 IU/ml in psoriasis vs. 9.3 ± 12.3 in control. Thirty percent of psoriasis patients have positive rheumatoid factor vs. 10% of control. There was no significant statistical difference between psoriasis patients with or without arthritis as regard rheumatoid factor positivity and titer; rheumatoid factor was positive in 20% in psoriatic patients with arthritis vs. 26% in psoriatic patients without arthritis. In psoriatic patients, the status of rheumatoid factor did not relate to disease severity, onset, course, site of affection, presence of scalp, nail affection, and presence of dactylitis (p value>0.5). Conclusion Psoriasis was associated with higher seropositivity of RF compared to age-matched non-psoriatic healthy controls. Occurrence and level of rheumatoid factor were not associated with severity or clinical pattern of psoriasis.

scholarly journals The Relationship Between Hyperglycemia and the Rheumatoid Factor in the Serum of Diabetic Patients

2009 ◽  
Vol 6 (1) ◽  
pp. 99-105
Author(s):  
Baghdad Science Journal
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Healthy Subjects ◽  
Diabetic Patients ◽  
Diabetic Mellitus ◽  
Positive Rheumatoid Factor ◽  
Common Diseases ◽  
Males And Females ◽  
The Relationship ◽  
Apparently Healthy

This study was conducted to determine the relationship between two most common diseases in Iraqis patients , which are Diabetic mellitus (DM) and Rheumatoid Arthritis (RA); seeking rheumatoid factor in hyperglycemic sera. The results revealed that ; 62.5% of hyperglycemic (HG) patients had positive rheumatoid factor (RF) . No difference in number between both gender of HG patients (20 males and 20 females ) , RF reaction was nearly similar in males and females of HG patients ( 12 &13 respectively ) . Only 40% out of patient controls had positive RF . None of the apparently healthy subjects had positive RF .

scholarly journals Patterns of hybridization and cryptic introgression among one- and four-needled pinyon pines

2020 ◽  
Vol 126 (3) ◽  
pp. 401-411
Author(s):  
Ryan Buck ◽  
Sandra Hyasat ◽  
Alice Hossfeld ◽  
Lluvia Flores-Rentería
Keyword(s):  
Distinct Species ◽  
Hybrid Origin ◽  
Interspecific Mating ◽  
Nucleotide Polymorphisms ◽  
Intermediate Morphology ◽  
The Status ◽  
Number Variation ◽  
Genetic Clusters ◽  
Variable Morphology ◽  
Genetic Contributions

Abstract Background and Aims Pinyon pine hybridization is widely acknowledged, but the frequency of and contributors to such interspecific mating remain largely unstudied. Pinus quadrifolia has three to four needles per fascicle, suggesting that it is a result of hybridization between the five-needled P. juarezensis and the single-needled P. monophylla. In this study we address the taxonomic validity of P. juarezensis, the hybrid origin of P. quadrifolia and the presence of hybridization and intermediate morphology as a result of interspecific hybridization in this complex. Methods We address these questions by combining a genomic and morphological approach. We generated 1868 single nucleotide polymorphisms (SNPs) to detect genetic clusters using principal co-ordinates analyis, discriminant analysis of principal components, fastSTRUCTURE and ADMIXTURE analyses, and performed a morphological analysis of the leaves. Key Results We found that the five-needled pinyons did not differ genetically from the four-needled P. quadrifolia, reducing the status of P. juarezensis to P. quadrifolia. We also found no evidence that P. quadrifolia is of hybrid origin from P. juarezensis × P. monophylla but is instead a genetically distinct species with natural needle number variation that has yet to be explained. Hybridization does occur in this complex, but mostly between P. quadrifolia and P. californiarum, and less commonly between P. quadrifolia and P. monophylla. Interestingly, some hybrid derivatives were detected between both single-needled taxa, P. monophylla and P. californiarum, a hybrid combination that has not yet been proposed. Hybrids have intermediate morphology when they have similar genetic contributions from both parental species; however, when one parent contributes more, hybrid derivatives resemble the parent with higher genetic contribution, resulting in cryptic introgression. Conclusions Our detailed sampling across the distribution of this complex allows us to describe the patterns of hybridization among these taxa, resolves an ancient taxonomic conflict and provides insights into the challenges of exclusively using morphological traits when identifying these taxa with cryptic hybridization and variable morphology.

scholarly journals The Immediate Pulmonary Disease Pattern following Exposure to High Concentrations of Chlorine Gas

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Pallavi P. Balte ◽  
Kathleen A. Clark ◽  
Lawrence C. Mohr ◽  
Wilfried J. Karmaus ◽  
David Van Sickle ◽  
...  
Keyword(s):  
South Carolina ◽  
Pulmonary Disease ◽  
Mass Casualty ◽  
Mass Casualties ◽  
High Concentration ◽  
Disease Patterns ◽  
Chlorine Gas ◽  
Disease Pattern ◽  
High Concentrations ◽  
Gas Inhalation

Background. Classification of pulmonary disease into obstructive, restrictive, and mixed patterns is based on 2005 ATS/ERS guidelines and modified GOLD criteria by Mannino et al. (2003), but these guidelines are of limited use for simple spirometry in situations involving mass casualties.Aim. The purpose of this study was to apply these guidelines to patients who underwent simple spirometry following high concentration of chlorine gas inhalation after a train derailment in Graniteville, South Carolina.Methods. We retrospectively investigated lung functions in ten patients. In order to classify pulmonary disease pattern, we used 2005 ATS/ERS guidelines and modified GOLD criteria along with our own criteria developed using available simple spirometry data.Results. We found predominant restrictive pattern in our patients with both modified GOLD and our criteria, which is in contrast to other chlorine exposure studies where obstructive pattern was more common. When compared to modified GOLD and our criteria, 2005 ATS/ERS guidelines underestimated the frequency of restrictive disease.Conclusion. Diagnosis of pulmonary disease patterns is of importance after irritant gas inhalation. Acceptable criteria need to be developed to evaluate pulmonary disease through simple spirometry in events leading to mass casualty and patient surge in hospitals.

RS3PE Syndrome With Positive Rheumatoid Factor

2019 ◽  
Vol 15 (6) ◽  
pp. e168-e169
Author(s):  
Fernando Moreno Obregón ◽  
Matilde del Castillo Madrigal ◽  
Fernando Díaz Narváez ◽  
Francisco Javier Pérez Delgado
Keyword(s):  
Rheumatoid Factor ◽  
Positive Rheumatoid Factor ◽  
Rs3pe Syndrome

scholarly journals The State of the Art of Traditional Arab Herbal Medicine in the Eastern Region of the Mediterranean: A Review

2006 ◽  
Vol 3 (2) ◽  
pp. 229-235 ◽  
Author(s):  
Hassan Azaizeh ◽  
Bashar Saad ◽  
Khalid Khalil ◽  
Omar Said
Keyword(s):  
Herbal Medicine ◽  
State Of The Art ◽  
Signs And Symptoms ◽  
Underlying Disease ◽  
The State ◽  
Complementary Alternative Medicine ◽  
Eastern Region ◽  
Know How ◽  
The Status ◽  
The Mediterranean

Historical and current studies indicate that the Eastern region of the Mediterranean has been distinguished from other regions by a rich inventory of complementary alternative medicine (CAM), in particular herbal medicine. Data collected from several surveys and studies indicate that there is a flourishing and well-developed trade of herbs. These surveys also reveal that 200–250 herbs are used in treating human diseases and are sold or traded in market places in the Mediterranean region or internationally. In addition, some of these herbs are rare or even endangered species. In regard to the status of the know-how of herbalists, unfortunately, herbal medicine in our region is mostly prescribed by ethnopharmacologists symptomatically—based on signs and symptoms alone, rather than as a result of a full understanding of the underlying disease. In some cases, herbs used today may not even correspond to the plants described originally in the old literature, as the former are cultivated from herbs that went through different breeding procedures throughout several centuries. This article presents a systematic review of both the state of the art of traditional Arab herbal medicine and the status of the know-how of Arab herbalists.

scholarly journals Relationship between Oral Health Status and Hematological Values in Pediatric Leukemic Patients: An Evaluative Survey

2014 ◽  
Vol 15 (5) ◽  
pp. 614-617
Author(s):  
Karthik Venkataraghavan ◽  
Udita Majithia
Keyword(s):  
Platelet Count ◽  
Health Status ◽  
Oral Health ◽  
Hematological Parameters ◽  
Signs And Symptoms ◽  
Oral Health Status ◽  
The Status ◽  
Dmft Index ◽  
Wbc Count ◽  
Hematological Values

ABSTRACT Introduction Leukemia is a malignancy of the bone marrow and constitutes 30% of all childhood cancers. The leukemic condition itself and its therapy cause oral signs and symptoms with significant morbidity. Aims and objectives The aim of this study was to review the oral health status in children with leukemia and relate the gingival and periodontal findings to the changes in their hematological values. Materials and method The oral health status in 47 pediatric leukemic patients in the age group of 6 to 14 years was assessed using the dmft/DMFT index, OHI(S) index and modified gingival index (MGI). Their hematological reports on the day of examination were obtained. The patients were divided into three groups based on the status of treatment. The relation between the platelet count and the WBC count with the MGI score was checked. Results The highest dmf and DMF scores were seen in patients who were currently under treatment. Though an inverse relation was seen between the platelet count and the MGI score, a statistically significant value was not obtained. Conclusion A longitudinal follow-up of patients should be carried out in order to establish a relation between the hematological parameters and the gingival inflammation score. How to cite this article Venkataraghavan K, Majithia U, Choudhary P, Trivedi K, Shah S. Relationship between Oral Health Status and Hematological Values in Pediatric Leukemic Patients: An Evaluative Survey. J Contemp Dent Pract 2014; 15(5):614-617.

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