Phase I dose-finding and pharmacokinetic study of IV vinflunine in combination with methotrexate in patients with recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) previously treated with platinum-based chemotherapy.

Audrey Mailliez; Frederic Rolland; Jean Marc Tourani; Cedrik Lafond; Didier Cupissol; Nicolas Isambert

doi:10.1200/jco.2015.33.15_suppl.e17049

Phase I dose-finding and pharmacokinetic study of IV vinflunine in combination with methotrexate in patients with recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) previously treated with platinum-based chemotherapy.

Journal of Clinical Oncology ◽

10.1200/jco.2015.33.15_suppl.e17049 ◽

2015 ◽

Vol 33 (15_suppl) ◽

pp. e17049-e17049

Author(s):

Audrey Mailliez ◽

Frederic Rolland ◽

Jean Marc Tourani ◽

Cedrik Lafond ◽

Didier Cupissol ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Pharmacokinetic Study ◽

Dose Finding ◽

Platinum Based Chemotherapy ◽

Metastatic Squamous Cell Carcinoma ◽

Previously Treated

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A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix

European Journal of Cancer ◽

10.1016/j.ejca.2004.12.013 ◽

2005 ◽

Vol 41 (4) ◽

pp. 523-530 ◽

Cited By ~ 65

Author(s):

Jennifer J. Knox ◽

Lillian L. Siu ◽

Eric Chen ◽

Jim Dimitroulakos ◽

Suzanne Kamel-Reid ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Phase I Trial ◽

Prolonged Administration ◽

Metastatic Squamous Cell Carcinoma

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A phase I dose-finding study of metformin in combination with concurrent cisplatin and radiation in patients with locally advanced head and neck squamous cell carcinoma.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.15_suppl.6074 ◽

2018 ◽

Vol 36 (15_suppl) ◽

pp. 6074-6074

Author(s):

Shuchi Gulati ◽

Benyamin Yaniv ◽

Sarah Palackdharry ◽

Vinita Takiar ◽

Michelle Lynn Mierzwa ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Locally Advanced ◽

Dose Finding ◽

Advanced Head ◽

Finding Study ◽

Dose Finding Study

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97 Phase I study of cetuximab (C225)in combination with cisplatin or carboplatin and 5-fluorouracil (5-FU) in patients (pts) with recurrent and/or metastatic squamous cell carcinoma of the head and neck (R&M SCCHN)

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(03)90130-3 ◽

2003 ◽

Vol 1 (5) ◽

pp. S34 ◽

Cited By ~ 1

Author(s):

J. Bourhis ◽

F. Rivera ◽

R. Mesia ◽

A. Awada ◽

L. Geoffrois ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Phase I Study ◽

Metastatic Squamous Cell Carcinoma

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A phase I stndy of a fixed dose of cisplatin with increasing doses of raltitrexed (Tomudex®) in the treatment of patients with locally advanced or metastatic squamous cell carcinoma of the head and neck.

Annals of Oncology ◽

10.1023/a:1011140810872 ◽

2001 ◽

Vol 12 (3) ◽

pp. 357-363 ◽

Cited By ~ 3

Author(s):

D. Ten Bokkel Huinink ◽

M.E.T. Tesselaar ◽

R.J. Baatenburg de Jong ◽

H.P. Verschuur ◽

H.J. Keizer

Keyword(s):

Squamous Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Locally Advanced ◽

Fixed Dose ◽

Metastatic Squamous Cell Carcinoma

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Phase I study of cetuximab in combination with cisplatin or carboplatin and 5-fluorouracil (5-FU) in patients (pts) with recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN)

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.90140.5513 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 5513-5513 ◽

Cited By ~ 4

Author(s):

Y. Humblet ◽

E. Vega-Villegas ◽

R. Mesia ◽

A. Awada ◽

L. Geoffrois ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Phase I Study ◽

Metastatic Squamous Cell Carcinoma

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Randomized phase II study of cabazitaxel versus methotrexate in patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN) previously treated with platinum-based therapy.

Journal of Clinical Oncology ◽

10.1200/jco.2015.33.15_suppl.6051 ◽

2015 ◽

Vol 33 (15_suppl) ◽

pp. 6051-6051

Author(s):

Sylvie Rottey ◽

Aline Van Maanen ◽

Jean-Marie Vandenbulcke ◽

Bertrand Filleul ◽

Emmanuel Seront ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Head And Neck ◽

Phase Ii ◽

Squamous Cell ◽

Phase Ii Study ◽

Randomized Phase Ii ◽

Metastatic Squamous Cell Carcinoma ◽

Previously Treated

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Results of a phase II study evaluating monalizumab in combination with cetuximab in previously treated recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN)

Annals of Oncology ◽

10.1093/annonc/mdy287.005 ◽

2018 ◽

Vol 29 ◽

pp. viii374 ◽

Cited By ~ 8

Author(s):

J. Fayette ◽

G. Lefebvre ◽

M.R. Posner ◽

J. Bauman ◽

S. Salas ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Head And Neck ◽

Phase Ii ◽

Squamous Cell ◽

Phase Ii Study ◽

Metastatic Squamous Cell Carcinoma ◽

Previously Treated

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Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: an open-label, randomised phase 3 trial

The Lancet Oncology ◽

10.1016/s1470-2045(11)70034-1 ◽

2011 ◽

Vol 12 (4) ◽

pp. 333-343 ◽

Cited By ~ 165

Author(s):

Jean-Pascal Machiels ◽

Somasundaram Subramanian ◽

Agnes Ruzsa ◽

Gabor Repassy ◽

Igor Lifirenko ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Supportive Care ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Best Supportive Care ◽

Open Label ◽

Phase 3 ◽

Platinum Based Chemotherapy ◽

Metastatic Squamous Cell Carcinoma

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Clinical outcomes of platinum-based chemotherapy plus cetuximab for recurrent or metastatic squamous cell carcinoma of the head and neck: comparison between platinum-sensitive and platinum-resistant patients

Acta Oto-Laryngologica ◽

10.1080/00016489.2018.1551623 ◽

2019 ◽

Vol 139 (2) ◽

pp. 201-205 ◽

Cited By ~ 2

Author(s):

Hiroki Sato ◽

Kiyoaki Tsukahara ◽

Isaku Okamoto ◽

Yasuaki Katsube ◽

Akira Shimizu ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Head And Neck ◽

Clinical Outcomes ◽

Squamous Cell ◽

Platinum Sensitive ◽

Platinum Resistant ◽

Platinum Based Chemotherapy ◽

Metastatic Squamous Cell Carcinoma

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Cisplatin, raltitrexed, levofolinic acid and 5-fluorouracil in locally advanced or metastatic squamous cell carcinoma of the head and neck: A phase I–II trial of the Southern Italy Cooperative Oncology Group (SICOG)

Annals of Oncology ◽

10.1023/a:1008339428733 ◽

2000 ◽

Vol 11 (5) ◽

pp. 575-580 ◽

Cited By ~ 7

Author(s):

F. Caponigro ◽

P. Cornelia ◽

F. Rivellini ◽

A. Avallone ◽

A. Budillon ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Southern Italy ◽

Locally Advanced ◽

Oncology Group ◽

Metastatic Squamous Cell Carcinoma

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