scholarly journals 45Ca UPTAKE AND TISSUE Ca OF GUINEA PIG TAENIA COLI IN ISOTONIC HIGH-K/Na-DEFICIENT MEDIUM

1968 ◽  
Vol 18 (3) ◽  
pp. 294-298 ◽  
Author(s):  
NORIMOTO URAKAWA ◽  
HIDEAKI KARAKI ◽  
MIYOSHI IKEDA
Keyword(s):  
Guinea Pig ◽  
Taenia Coli ◽  
45Ca Uptake ◽  
High K ◽  
Deficient Medium

scholarly journals MECHANICAL RESPONSE OF GUINEA PIG TAENIA COLI IN HIGH-K/Na-DEFICIENT MEDIUM UNDER ANOXIA

1969 ◽  
Vol 19 (2) ◽  
pp. 329-330 ◽  
Author(s):  
S.S. GANESHANANDAN ◽  
HIDEAKI KARAKI ◽  
MIYOSHI IKEDA ◽  
NORIMOTO URAKAWA
Keyword(s):  
Guinea Pig ◽  
Mechanical Response ◽  
Taenia Coli ◽  
High K ◽  
Deficient Medium

scholarly journals Inhibitory effect of beauvericin on a high K+-induced tonic contraction in guinea-pig taenia coli.

1987 ◽  
Vol 45 (3) ◽  
pp. 317-325 ◽  
Author(s):  
Shinjiro NAKAJYO ◽  
Kiyomi MATSUOKA ◽  
Tomohiro KITAYAMA ◽  
Yutaka YAMAMURA ◽  
Kazumasa SHIMIZU ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Inhibitory Effect ◽  
Tonic Contraction ◽  
Taenia Coli ◽  
High K

scholarly journals DUAL ACTIONS OF VANADATE ON HIGH K-INDUCED CONTRACTION IN GUINEA-PIG TAENIA COLI

1982 ◽  
Vol 32 (1) ◽  
pp. 149-157
Author(s):  
Fukiko UEDA ◽  
Tadashi KISHIMOTO ◽  
Hiroshi OZAKI ◽  
Norimoto URAKAWA
Keyword(s):  
Guinea Pig ◽  
Taenia Coli ◽  
High K

scholarly journals EFFECT OF LITHIUM SUBSTITUTION FOR SODIUM ON OXYGEN CONSUMPTION OF GUINEA PIG TAENIA COLI IN HIGH K MEDIUM

1970 ◽  
Vol 20 (3) ◽  
pp. 453-455 ◽  
Author(s):  
YUKIO SAITO ◽  
YUTAKA SAKAI ◽  
MIYOSHI IKEDA ◽  
NORIMOTO URAKAWA
Keyword(s):  
Oxygen Consumption ◽  
Guinea Pig ◽  
Taenia Coli ◽  
High K

The uptake and efflux of α-aminoisobutyric acid by the smooth muscle of the guinea pig's taenia coli

1979 ◽  
Vol 57 (10) ◽  
pp. 1114-1121
Author(s):  
J. H. Widdicombe ◽  
D. M. Paton
Keyword(s):  
Smooth Muscle ◽  
Guinea Pig ◽  
Effective Treatment ◽  
Taenia Coli ◽  
Free Medium ◽  
Efflux Rate ◽  
Aminoisobutyric Acid ◽  
High K ◽  
Treatment Changes ◽  
High Concentrations

The uptake of α-aminoisobutyric acid (AIB) by guinea pig taenia coli was linear with time over a 5-h period. There was a saturable component with Km of 0.7 mM and a maximal value of 4.75 mmol/kg tissue per hour. A second nonsaturable component of uptake became important at high concentrations of AIB (> 5 mM). Preincubation in K+-free or Na+-free (high-K+) media greatly reduced uptake. The dependence of AIB uptake on outside [Na+] ([Na+]0) was approximately linear over the range 0–140 mM. With [Na+]0 equal to 25 mM the uptakes with various substitutes were in the order sucrose > Mg2+ > choline+ > Li+ > Cs+ > Rb+ = K+. Addition of ouabain or removal of K+ during efflux of AIB led to marked increases in the efflux rate, ouabain being the more effective treatment. Changes in tissue Na+ and K+ levels were found to be slightly greater with ouabain than with K+-free medium. Lanthanum (5 mM) prevented the uptake of Na+ seen in K+-free medium and also abolished the increase in the rate of loss of AIB. It also reduced the rise in tissue Na+ produced by ouabain; there was a corresponding reduction in the ouabain-induced increase in the rate of loss of AIB. It is concluded that both the influx and efflux of AIB in this tissue are Na+ dependent, and that the accumulation of AIB relies on the transmembrane Na+ gradient.

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