Clinical impact of ultra-high b-value (3000 s/mm2) diffusion-weighted magnetic resonance imaging in prostate cancer at 3T: comparison with b-value of 2000 s/mm2

2021 ◽  
pp. 20210465
Author(s):  
Tsutomu Tamada ◽  
Ayumu Kido ◽  
Yu Ueda ◽  
Mitsuru Takeuchi ◽  
Takeshi Fukunaga ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diagnostic Performance ◽  
Signal To Noise Ratio ◽  
B Value ◽  
Single Shot ◽  
Signal To Noise ◽  
High B Value ◽  
Diffusion Weighted ◽  
Significant Difference ◽  
Noise Ratio

Objective: High b-value diffusion-weighted imaging (hDWI) with a b-value of 2000 s/mm2 provides insufficient image contrast between benign and malignant tissues and an overlap of apparent diffusion coefficient (ADC) between Gleason grades (GG) in prostate cancer (PC). We compared image quality, PC detectability, and discrimination ability for PC aggressiveness between ultra-high b-value DWI (uhDWI) of 3000 s/mm2 and hDWI. Methods: The subjects were 49 patients with PC who underwent 3T multiparametric MRI. Single-shot echo-planar DWI was acquired with b-values of 0, 2000, and 3000 s/mm2. Anatomical distortion of prostate (AD), signal intensity of benign prostate (PSI), and lesion conspicuity score (LCS) were assessed using a 4-point scale; and signal-to-noise ratio, contrast-to-noise ratio, and mean ADC (×10–3 mm2/s) of lesion (lADC) and surrounding benign region (bADC) were measured. Results: PSI was significantly lower in uhDWI than in hDWI (p < 0.001). AD, LCS, signal-to-noise ratio, and contrast-to-noise ratio were comparable between uhDWI and hDWI (all p > 0.05). In contrast, lADC was significantly lower than bADC in both uhDWI and hDWI (both p < 0.001). In comparison of lADC between tumors of ≤GG2 and those of ≥GG3, both uhDWI and hDWI showed significant difference (p = 0.007 and p = 0.021, respectively). AUC for separating tumors of ≤GG2 from those of ≥GG3 was 0.731 in hDWI and 0.699 in uhDWI (p = 0.161). Conclusion: uhDWI suppressed background signal better than hDWI, but did not contribute to increased diagnostic performance in PC. Advances in knowledge: Compared with hDWI, uhDWI could not contribute to increased diagnostic performance in PC.

scholarly journals Assessing Stability of Crutch Users by Non-Contact Methods

2021 ◽  
Vol 18 (6) ◽  
pp. 3001
Author(s):  
Achilles Vairis ◽  
Suzana Brown ◽  
Maurice Bess ◽  
Kyu Hyun Bae ◽  
Jonathan Boyack
Keyword(s):  
Signal To Noise Ratio ◽  
Time Derivative ◽  
Assistive Devices ◽  
Signal To Noise ◽  
Physically Disabled ◽  
Significant Difference ◽  
Novice Users ◽  
Noise Ratio ◽  
Physically Disabled People

Enhancing gait stability in people who use crutches is paramount for their health. With the significant difference in gait compared to users who do not require an assistive device, the use of standard gait analysis tools to measure movement for temporary crush users and physically disabled people proves to be more challenging. In this paper, a novel approach based on video analysis is proposed as non-contact low-cost solution to the more expensive alternative with the data collected from processed videos, two values are calculated: the Signal to Noise Ratio (SNR) of acceleration, and the Signal to Noise Ratio of the jerk (time derivative of acceleration), to assess the user’s stability while they walk with crutches. The adopted methodology has been tested on a total of 10 participants. Five are temporary users of assistive devices with one being a long-term user and the other four novice users, and five are disabled participants who use those assistive devices permanently. Preliminary results show differences between novice users, long-term users, and physically disabled users. The approach is promising and could improve the assessment of crutch user stability, allowing for the correction of gait for individuals while using an inexpensive non-contact setup and preventing unnecessary falls.

The Influence of Alteration of kVp and mAs towards the Image Quality of Acrylic Using CBCT

2019 ◽  
Vol 829 ◽  
pp. 252-257
Author(s):  
Azhari ◽  
Yohanes Hutasoit ◽  
Freddy Haryanto
Keyword(s):  
Image Quality ◽  
Signal To Noise Ratio ◽  
Region Of Interest ◽  
Signal To Noise ◽  
Bite Block ◽  
Significant Difference ◽  
Noise Ratio ◽  
Post Hoc ◽  
Radiograph Image

CBCT is a modernized technology in producing radiograph image on dentistry. The image quality excellence is very important for clinicians to interpret the image, so the result of diagnosis produced becoming more accurate, appropriate, thus minimizing the working time. This research was aimed to assess the image quality using the blank acrylic phantom polymethylmethacrylate (PMMA) (C­5H8O2)n in the density of 1.185 g/cm3 for evaluating the homogeneity and uniformity of the image produced. Acrylic phantom was supported with a tripod and laid down on the chin rest of the CBCT device, then the phantom was fixed, and the edge of the phantom was touched by the bite block. Furthermore, the exposure of the X-ray was executed toward the acrylic phantom with various kVp and mAs, from 80 until 90, with the range of 5 kV and the variation of mA was 3, 5, and 7 mA respectively. The time exposure was kept constant for 25 seconds. The samples were taken from CBCT acrylic images, then as much as 5 ROIs (Region of Interest) was chosen to be analyzed. The ROIs determination was analyzed by using the ImageJ® software for recognizing the influence of kVp and mAs towards the image uniformity, noise and SNR. The lowest kVp and mAs had the result of uniformity value, homogeneity and signal to noise ratio of 11.22; 40.35; and 5.96 respectively. Meanwhile, the highest kVp and mAs had uniformity value, homogeneity and signal to noise ratio of 16.96; 26.20; and 5.95 respectively. There were significant differences between the image uniformity and homogeneity on the lowest kVp and mAs compared to the highest kVp and mAs, as analyzed with the ANOVA statistics analysis continued with the t-student post-hoc test with α = 0.05. However, there was no significant difference in SNR as analyzed with the ANOVA statistic analysis. The usage of the higher kVp and mAs caused the improvement of the image homogeneity and uniformity compared to the lower kVp and mAs.

Image quality and diagnostic accuracy of complex-averaged high b value images in diffusion-weighted MRI of prostate cancer

2019 ◽  
Vol 44 (6) ◽  
pp. 2244-2253 ◽  
Author(s):  
Hamed Kordbacheh ◽  
Ravi Teja Seethamraju ◽  
Elisabeth Weiland ◽  
Berthold Kiefer ◽  
Marcel Dominik Nickel ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Image Quality ◽  
Diagnostic Accuracy ◽  
B Value ◽  
Diffusion Weighted Mri ◽  
High B Value ◽  
Diffusion Weighted

scholarly journals A signal to noise ratio measurement for single shot laser pulses by use of an optical Kerr gate

2011 ◽  
Vol 19 (5) ◽  
pp. 4438 ◽  
Author(s):  
Junfang He ◽  
Changjun Zhu ◽  
Yishan Wang ◽  
Guanghua Cheng ◽  
Kuaisheng Zou ◽  
...  
Keyword(s):  
Signal To Noise Ratio ◽  
Laser Pulses ◽  
Single Shot ◽  
Signal To Noise ◽  
Ratio Measurement ◽  
Optical Kerr Gate ◽  
Noise Ratio

scholarly journals Accuracy of high b-value diffusion-weighted MRI for prostate cancer detection: a meta-analysis

2017 ◽  
Vol 59 (1) ◽  
pp. 105-113 ◽  
Author(s):  
Keith Craig Godley ◽  
Tom Joseph Syer ◽  
Andoni Paul Toms ◽  
Toby Oliver Smith ◽  
Glyn Johnson ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diagnostic Accuracy ◽  
Sensitivity And Specificity ◽  
Cancer Detection ◽  
Diagnostic Performance ◽  
Visual Assessment ◽  
B Value ◽  
B Values ◽  
Prostate Cancer Detection ◽  
High B Value

Background The diagnostic accuracy of diffusion-weighted imaging (DWI) to detect prostate cancer is well-established. DWI provides visual as well as quantitative means of detecting tumor, the apparent diffusion coefficient (ADC). Recently higher b-values have been used to improve DWI’s diagnostic performance. Purpose To determine the diagnostic performance of high b-value DWI at detecting prostate cancer and whether quantifying ADC improves accuracy. Material and Methods A comprehensive literature search of published and unpublished databases was performed. Eligible studies had histopathologically proven prostate cancer, DWI sequences using b-values ≥ 1000 s/mm2, less than ten patients, and data for creating a 2 × 2 table. Study quality was assessed with QUADAS-2 (Quality Assessment of diagnostic Accuracy Studies). Sensitivity and specificity were calculated and tests for statistical heterogeneity and threshold effect performed. Results were plotted on a summary receiver operating characteristic curve (sROC) and the area under the curve (AUC) determined the diagnostic performance of high b-value DWI. Results Ten studies met eligibility criteria with 13 subsets of data available for analysis, including 522 patients. Pooled sensitivity and specificity were 0.59 (95% confidence interval [CI], 0.57–0.61) and 0.92 (95% CI, 0.91–0.92), respectively, and the sROC AUC was 0.92. Subgroup analysis showed a statistically significant ( P = 0.03) improvement in accuracy when using tumor visual assessment rather than ADC. Conclusion High b-value DWI gives good diagnostic performance for prostate cancer detection and visual assessment of tumor diffusion is significantly more accurate than ROI measurements of ADC.

scholarly journals Feasibility study of using simultaneous multi-slice RESOLVE diffusion weighted imaging to assess parotid gland tumors: comparison with conventional RESOLVE diffusion weighted imaging

2020 ◽  
Author(s):  
Jia-Suo Jiang ◽  
Liu-Ning Zhu ◽  
Qian Wu ◽  
Yi Sun ◽  
Wei Liu ◽  
...  
Keyword(s):  
Image Quality ◽  
Parotid Gland ◽  
Diffusion Weighted Imaging ◽  
Signal To Noise Ratio ◽  
Anatomical Structure ◽  
Parotid Gland Tumors ◽  
Diffusion Weighted ◽  
Scan Time ◽  
Significant Difference ◽  
Noise Ratio

Abstract Background To evaluate the feasibility of using simultaneous multi-slice (SMS) readout segmentation of long variable echo-trains (RESOLVE) diffusion-weighted imaging (DWI) to assess parotid gland tumors, compared with conventional RESOLVE DWI Methods From September 2018 to December 2018, 20 consecutive patients with parotid tumors who underwent MRI scan for pre-surgery evaluation were enrolled. SMS-RESOLVE DWI and conventional RESOLVE DWI were scanned with matched imaging parameters, respectively. The scan time of two DWI sequences was recorded. Qualitative (anatomical structure differentiation, lesion display, artifact, and overall image quality) and quantitative (apparent diffusion coefficient, ADC; ratio of signal-to-noise ratio, SNR ratio; ratio of contrast-to-noise ratio, CNR ratio) assessments of image quality were performed, and compared between SMS-RESOLVE DWI and conventional RESOLVE DWI. Paired t-test was used for statistical analyses. Results The scan time was 3 minutes and 41 seconds for SMS-RESOLVE DWI, and 5 minutes and 46 seconds for conventional RESOLVE DWI. SMS-RESOLVE DWI produced similar qualitative image quality with RESOLVE DWI (anatomical structure differentiation, P = 0.164; lesion display, P = 0.193; artifact, P = 0.330; overall image quality, P = 0.083). Meanwhile, there were no significant difference on ADCLesion (P = 0.298), ADCMasseter (P = 0.122), SNR ratio (P = 0.584) and CNR ratio (P = 0.217) between two DWI sequences. Conclusion Compared with conventional RESOLVE DWI, SMS-RESOLVE DWI could provide comparable image quality using markedly reduced scan time. SMS could increase the clinical usability of RESOLVE technique for DWI of parotid gland.

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