scholarly journals Case Report: Adult Onset Still’s Disease after vaccination against Covid-19

2021 ◽  
Vol 6 ◽  
pp. 333
Author(s):  
Ujjwol Risal ◽  
Anup Subedee ◽  
Raju Pangeni ◽  
Rakshya Pandey ◽  
Suravi Pandey ◽  
...  
Keyword(s):  
Adult Onset Still’S Disease ◽  
Temporal Association ◽  
Adult Onset ◽  
Still’S Disease ◽  
High Grade Fever ◽  
Serious Adverse Events ◽  
Mortality And Morbidity ◽  
Still's Disease ◽  
Adult Onset Still's Disease ◽  
Multiple Antibiotics

Vaccination against the virus responsible for COVID-19 has become a key in preventing mortality and morbidity related to the infection. Studies have shown that the benefits of vaccination outweigh the risks. However, there are concerns regarding serious adverse events of some vaccines,      although they are fortunately      rare. Here, we report a case of a 47-year-old female from Kathmandu who presented with high grade fever, dry cough and erythematous rash a week after exposure to the Oxford-AstraZeneca vaccine. She had hepatosplenomegaly, persistent leucocytosis, anaemia and thrombocytosis along with markedly raised inflammatory markers. Her tests for infectious causes and haematological malignancies was negative and she showed no response to multiple antibiotics. Finally, she had a dramatic response to steroids with disappearance of fever and normalization of other laboratory parameters. Hence, she was diagnosed with       Adult-onset Still’s      Disease (AOSD). She was under methotrexate and prednisolone tapering dose and doing well as at time of writing. The trigger for the disease was hypothesized to be the vaccine because of the strong temporal association.

scholarly journals Adult onset still’s disease: a diagnostic dilemma

2019 ◽  
Vol 6 (6) ◽  
pp. 1950
Author(s):  
Dugganapalli Dinesh Kumar Reddy ◽  
Veeraballi Sindhusha ◽  
Metta Jagadeesh
Keyword(s):  
Adult Onset Still’S Disease ◽  
Inflammatory Disorder ◽  
Adult Onset ◽  
Unknown Aetiology ◽  
Still’S Disease ◽  
High Grade Fever ◽  
Diagnostic Dilemma ◽  
Still's Disease ◽  
Clinical Triad ◽  
Adult Onset Still's Disease

Adult onset still’s disease is a rare systemic inflammatory disorder of unknown aetiology, characterized by clinical triad (high spiking fever, evanescent rash and arthritis) and biological triad with lack of serological markers as a true gold standard makes diagnosis difficulty. Here is a case of 32year old male presented with high grade fever for 2 months, joint pains and swelling for 1month rash for 3 days. O/E: pallor and B/L tender, swollen ankle and knee joints, and P/A: splenomegaly. Investigations showed-Hb%. 8 gms, neutrophilic leucocytosis with thrombocytosis, ESR:72 mm/1h, CRP elevated. ASO-titre, RA factor and Anti CCP antibodies are negative. Adult onset still’s disease is a heterogenous and rare systemic inflammatory disorder of unknown aetiology with lack of serological diagnostic modalities.

scholarly journals Pulmonary artery hypertension prior to the relapse of adult‐onset Still's disease

2021 ◽  
Vol 9 (5) ◽  
Author(s):  
Yuki Hara ◽  
Takayoshi Morita ◽  
Katsunao Tanaka ◽  
Fusako Sera ◽  
Yasushi Sakata ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Pulmonary Artery Hypertension ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease

scholarly journals Aseptic Meningitis and Cranial Nerve Palsy Revealing Adult‐Onset Still's Disease

1999 ◽  
Vol 29 (1) ◽  
pp. 220-221 ◽  
Author(s):  
I. Marie ◽  
H. Levesque ◽  
N. Perraudin ◽  
N. Cailleux ◽  
F. Lecomte ◽  
...  
Keyword(s):  
Aseptic Meningitis ◽  
Cranial Nerve ◽  
Cranial Nerve Palsy ◽  
Nerve Palsy ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease

Markedly increased IL-18 liver expression in adult-onset Still's disease-related hepatitis

Rheumatology ◽  
2010 ◽  
Vol 50 (4) ◽  
pp. 776-780 ◽  
Author(s):  
R. Priori ◽  
F. Barone ◽  
C. Alessandri ◽  
S. Colafrancesco ◽  
I. B. McInnes ◽  
...  
Keyword(s):  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease

THU0403 Scd163 in Adult Onset Still's Disease: A Biomarker for Macrophage Activation Related to Hyperferritinemia:

2014 ◽  
Vol 73 (Suppl 2) ◽  
pp. 321.1-321
Author(s):  
S. Colafrancesco ◽  
R. Priori ◽  
E. Astorri ◽  
C. Perricone ◽  
N. Agmon-Levin ◽  
...  
Keyword(s):  
Macrophage Activation ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease
Sign in / Sign up

Export Citation Format

Share Document