scholarly journals Transcriptional inhibition of feline immunodeficiency virus by alpha-amanitin

Author(s):  
Taishi TANABE ◽  
Yurina FUKUDA ◽  
Kazuhiko KAWASHIMA ◽  
Satomi YAMAMOTO ◽  
Takashige KASHIMOTO ◽  
...  
1994 ◽  
Vol 68 (7) ◽  
pp. 4572-4579 ◽  
Author(s):  
F Baldinotti ◽  
D Matteucci ◽  
P Mazzetti ◽  
C Giannelli ◽  
P Bandecchi ◽  
...  

2019 ◽  
Vol 5 (2) ◽  
pp. 205511691987087
Author(s):  
Cesaltina CLM Tchamo ◽  
Mónica De Rugeriis ◽  
Emília V Noormahomed

Objectives Feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) are immunosuppressive viruses in cats that increase their susceptibility to zoonotic pathogens. This study aimed to determine the occurrence of one or both viruses, the risk factors associated with infection, and to develop further recommendations. Methods This was a cross-sectional study conducted at the Veterinary Faculty of Eduardo Mondlane University, Mozambique, between March and December 2017, in 145 cats. From each of 145 cats, we took 1.5 ml of blood by jugular puncture for detection of antibodies to FIV and FeLV antigens in whole blood using a commercial test kit, DFV Test FeLV/FIV. Results We found an overall prevalence of 11.0% and 14.5% for FIV antibodies and FeLV antigens, respectively, with four (2.8%) cats coinfected by both pathogens. Male cats were more likely to be infected with FIV (odds ratio [OR] 1.1, 95% confidence interval [CI] 0.3–4.0) compared with female cats. Clinically ill cats were more likely to have a positive result for FeLV antigen infection (OR 18.8, 95% CI 5.2–68.3). Moreover, cats living in suburban areas have a greater chance of a positive result for FeLV infection (OR 3.7, 95% CI 1.4–9.6) compared with cats living in urban areas. Conclusions and relevance FIV and FeLV occur in cats from Maputo and possibly all over the country. Further studies should be conducted in Mozambique and other African countries to define the burden of both pathogens in cats, coinfection with other zoonotic pathogens and the possible role played by the cats on the transmission of zoonotic and opportunistic diseases to humans.


2021 ◽  
Vol 8 (2) ◽  
pp. 16
Author(s):  
Xinyu Chi ◽  
Kexin Fang ◽  
Liza Koster ◽  
Jevan Christie ◽  
Chaoqun Yao

Toxoplasma gondii (T. gondii) is a cosmopolitan protozoan parasite that infects all warm-blooded species including humans. The definitive hosts of T. gondii are felid vertebrates including the domestic cat. Domestic cats shed oocysts for approximately two weeks in their feces after the primary infection. It has been shown that feline immunodeficiency virus (FIV) positive cats have a higher prevalence of and a higher titer of antibodies to T. gondii than those of FIV-negative cats. The main purposes of this study were to determine FIV prevalence and to investigate the oocysts shedding in FIV-positive and FIV-negative feral cats on St. Kitts. Fecal samples were collected from feral cats while their FIV statues were determined using a commercial SNAP kit. Total fecal DNA of each cat was tested for the presence of T. gondii DNA using a polymerase chain reaction (PCR) consistently detecting one genome equivalent. A FIV-positive status was detected in 18 of 105 (17.1%, 95% confidence interval (CI): 9.9%−24.3%) feral cats sampled. Furthermore, males were three times more likely to be FIV positive than females (p = 0.017) with an odds ratio of 3.93 (95% CI: 1.20–12.89). Adults were found to have at least twice the prevalence of FIV compared to cats younger than one year of age (p = 0.056) with an odds ratio of 3.07 (95% CI: 0.94–10.00). Toxoplasma gondii DNA was not detected in the feces of any of the 18 FIV-positive (95% CI: 0%−0.18%) and 87 FIV-negative cats (95% CI: 0%−0.04%). A follow-up study with a much bigger sample size is needed to prove or disprove the hypothesis that FIV-positive cats have a higher prevalence of shedding T. gondii oocysts than FIV-negative cats.


1992 ◽  
Vol 148 (5) ◽  
pp. 399-412 ◽  
Author(s):  
M. Bennett ◽  
N.R. Smyth

2009 ◽  
Vol 17 (14) ◽  
pp. 4916-4920 ◽  
Author(s):  
Shinya Oishi ◽  
Yasuyo Kodera ◽  
Hiroki Nishikawa ◽  
Hirotaka Kamitani ◽  
Tsuyoshi Watabe ◽  
...  

1997 ◽  
Vol 13 (7) ◽  
pp. 611-620 ◽  
Author(s):  
MARLENE S. ORANDLE ◽  
GEORGE P. PAPADI ◽  
LORETTA J. BUBENIK ◽  
CARYL I. DAILEY ◽  
CALVIN M. JOHNSON

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