scholarly journals DNA Methylation Profiles of the Brain-Derived Neurotrophic Factor (BDNF) Gene as a Potent Diagnostic Biomarker in Major Depression

PLoS ONE ◽  
2011 ◽  
Vol 6 (8) ◽  
pp. e23881 ◽  
Author(s):  
Manabu Fuchikami ◽  
Shigeru Morinobu ◽  
Masahiro Segawa ◽  
Yasumasa Okamoto ◽  
Shigeto Yamawaki ◽  
...  
2021 ◽  
Vol 17 (7) ◽  
pp. 1371-1379
Author(s):  
Di Liu ◽  
Ying Li ◽  
Jiechen Liu ◽  
Zhiyuan Shen ◽  
Fengying Wang ◽  
...  

Occlusal trauma (OT), by causing periodontal tissue damage, can activate and enhance the activity of the peripheral and central nervous system (CNS) neuropeptides. The brain-derived neurotrophic factor (BDNF) gene is activity-dependent and exhibits marked alterations, characterized by protection against injury and repair. Our results show the possible molecular mechanism through which noxious environmental stimuli induce alterations in BDNF activity in the local periodontal tissue, the primary sensory neurons-Vc, and the hippocampus, suggesting systemic impairment. BDNF serves a more positive and enduring trauma protection and repair function in Vc compared to that in local dental tissue.


2005 ◽  
Vol 58 (9) ◽  
pp. 738-742 ◽  
Author(s):  
Saffron A.G. Willis-Owen ◽  
Jan Fullerton ◽  
Paul G. Surtees ◽  
Nick W.J. Wainwright ◽  
Susette Miller ◽  
...  

2014 ◽  
Vol 29 (2) ◽  
pp. 384-392 ◽  
Author(s):  
Paolo Ghisletta ◽  
Lars Bäckman ◽  
Lars Bertram ◽  
Andreas Markus Brandmaier ◽  
Denis Gerstorf ◽  
...  

2003 ◽  
Vol 337 (1) ◽  
pp. 17-20 ◽  
Author(s):  
Kenji Nakata ◽  
Hiroshi Ujike ◽  
Ayumu Sakai ◽  
Naohiko Uchida ◽  
Akira Nomura ◽  
...  

2017 ◽  
Vol 39 (2) ◽  
pp. 90-94 ◽  
Author(s):  
Lucas A. de Azeredo ◽  
Tatiana De Nardi ◽  
Mateus L. Levandowski ◽  
Saulo G. Tractenberg ◽  
Julia Kommers-Molina ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document