scholarly journals Implementation of a National Measles Elimination Program in Iran: Phylogenetic Analysis of Measles Virus Strains Isolated during 2010–2012 Outbreaks

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e94846 ◽  
Author(s):  
Vahid Salimi ◽  
Simin Abbasi ◽  
Seyed Mohsen Zahraei ◽  
Ghazal Fatemi-Nasab ◽  
Fatemeh Adjaminezhad-Fard ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Measles Virus ◽  
Measles Elimination ◽  
Virus Strains

scholarly journals Measles and rubella in the North-West of Russia in period of elimination

2021 ◽  
Vol 13 (4) ◽  
pp. 106-112
Author(s):  
M. A. Bichurina ◽  
N. V. Zheleznova ◽  
A. A. Sharova
Keyword(s):  
Measles Virus ◽  
Laboratory Diagnostics ◽  
Serum Samples ◽  
North West ◽  
The North ◽  
Measles Elimination ◽  
Molecular Studies ◽  
High Level ◽  
Measles Incidence ◽  
Virus Strains

Aim: To evaluate the epidemic situation on measles and rubella and to carry out the laboratory diagnostics of these infections in the North-West of Russia in the period of elimination.Materials and Methods. In 2016-2019 a total of 534 blood serum samples from patients with measles diagnosis, 210 – from patients with rubella diagnosis and 1251 – from patients with exanthema were studied by ELISA using “VectoMeasles-IgM” and “EIA-Rubella-IgM” test-systems.Results. Measles incidence in NWR varied from 0 to 0.96 per 100,000 in 2016 and 2019, respectively. Among measles patients the proportion of children and adults changed in 2018-2019, adults constituted 65.9%. Patients not vaccinated against measles and those with the unknown vaccination status were mainly involved in epidemic process (85%). High level of patients with revaccination status was revealed in 2018 (18.4%). These patients demonstrated high levels of IgG (>3.0 IU/ml) as well as high percentage of IgG avidity (>94.3%) on 4-7th day of rash onset thus evidencing secondary immune response. Molecular studies of the samples from patients revealed the circulation of D8 and B3 genotypes of measles virus. Strains of D8 and B3 genotypes were represented by 3 and 4 variants, respectively. Rubella incidence did not exceed 0.13 per 100,000. Strains of rubella virus of genotype 1E were detected.Conclusion. The data of annual measles incidence and molecular studies of circulating wild type measles viruses prove the on-going measles elimination process in the NorthWest of Russia. For rubella, the persistent phase of elimination was demonstrated in the region. 

scholarly journals Complete Genome Sequences of Six Measles Virus Strains

2018 ◽  
Vol 6 (13) ◽  
Author(s):  
My V. T. Phan ◽  
Claudia M. E. Schapendonk ◽  
Bas B. Oude Munnink ◽  
Marion P. G. Koopmans ◽  
Rik L. de Swart ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Complete Genome ◽  
Measles Virus ◽  
Genetic Characterization ◽  
Critical Component ◽  
Wild Type ◽  
Genome Sequences ◽  
Virus Strains ◽  
Generation Sequencing

ABSTRACT Genetic characterization of wild-type measles virus (MV) strains is a critical component of measles surveillance and molecular epidemiology. We have obtained complete genome sequences of six MV strains belonging to different genotypes, using random-primed next generation sequencing.

scholarly journals Effective Radiovirotherapy for Malignant Gliomas by Using Oncolytic Measles Virus Strains Encoding the Sodium Iodide Symporter (MV-NIS)

2012 ◽  
Vol 23 (4) ◽  
pp. 419-427 ◽  
Author(s):  
Mateusz Opyrchal ◽  
Cory Allen ◽  
Ianko Iankov ◽  
Ileana Aderca ◽  
Mark Schroeder ◽  
...  
Keyword(s):  
Measles Virus ◽  
Sodium Iodide ◽  
Malignant Gliomas ◽  
Sodium Iodide Symporter ◽  
Virus Strains

Genetic and antigenic characterisation of the haemagglutinin protein of measles virus strains recently circulating in the UK

1998 ◽  
Vol 55 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Li Jin ◽  
Wendy A Knowles ◽  
Paul A Rota ◽  
William J Bellini ◽  
David W.G Brown
Keyword(s):  
Measles Virus ◽  
The Uk ◽  
Virus Strains

scholarly journals Oncolytic measles virus strains have significant antitumor activity against glioma stem cells

Gene Therapy ◽  
2012 ◽  
Vol 20 (4) ◽  
pp. 444-449 ◽  
Author(s):  
C Allen ◽  
M Opyrchal ◽  
I Aderca ◽  
M A Schroeder ◽  
J N Sarkaria ◽  
...  
Keyword(s):  
Stem Cells ◽  
Antitumor Activity ◽  
Measles Virus ◽  
Glioma Stem Cells ◽  
Virus Strains

scholarly journals Atypical presentation of Hand foot mouth disease (HFMD) caused by enterovirus serotype Coxsackievirus A6, in India

2019 ◽  
Author(s):  
Muruganandam Nagarajan ◽  
Itta Krishna Chaaithanya ◽  
Rehnuma Parvez ◽  
Surya Palani ◽  
Anwesh Maile ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Measles Virus ◽  
Mouth Disease ◽  
Epidemiological Surveillance ◽  
Low Grade ◽  
High Grade Fever ◽  
Varicella Zoster ◽  
Coxsackievirus A6 ◽  
History Of ◽  
Naval Hospital

A 27-year-old male presented in the OPD of Naval Hospital in Port Blair, Andaman Islands, India, in 2011 with a history of low-grade fever associated with malaise and a pruritic skin rash. Case 2 – A 17-year-old male student reported to the OPD at Naval Hospital, Kochi Kerala, India, in August 2015. He presented with eruptions on both the palm and soles with a history of high-grade fever for the past 3–4 days. Clinically, both the cases were diagnosed as hand, foot, and mouth disease (HFMD). Both samples were tested against measles virus and varicella-zoster IgM antibodies by enzyme immunoassay and found negative. Stool sample (case 1) and lesion swab (case 2) were processed by enterovirus reverse transcription polymerase chain reaction and phylogenetic analysis, and both were positive for enterovirus human coxsackievirus A6 (CVA6) (untranslated region [UTR]). Phylogenetic analysis also confirmed that both the CVA6 etiology belonged to the genotype F. HFMD in adults often asymptomatic and very few patients get atypical symptoms. Clinical diagnosis is often troublesome to identify HFMD in such cases. An epidemiological surveillance/vigilance is essential to document these atypical cases in near future in developing countries like India.

Replication of Clinical Measles Virus Strains in Hispid Cotton Rats

1999 ◽  
Vol 221 (1) ◽  
pp. 53-63 ◽  
Author(s):  
P. R. Wyde ◽  
D. K. Moore-Poveda ◽  
N. J. Daley ◽  
H. Oshitani
Keyword(s):  
Measles Virus ◽  
Cotton Rats ◽  
Virus Strains

Immunosuppression by measles virus strains: Relationship to virus replication

1988 ◽  
Vol 11 ◽  
pp. 77
Author(s):  
S. Vydelingum ◽  
K. Suryanarayana ◽  
R.G. Marusyk ◽  
A.A. Salmi
Keyword(s):  
Virus Replication ◽  
Measles Virus ◽  
Virus Strains
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