scholarly journals Assessing the Long-Term Impact of Treating Hepatitis C Virus (HCV)-Infected People Who Inject Drugs in the UK and the Relationship between Treatment Uptake and Efficacy on Future Infections

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0125846 ◽  
Author(s):  
Hayley Bennett ◽  
Phil McEwan ◽  
Daniel Sugrue ◽  
Anupama Kalsekar ◽  
Yong Yuan
1998 ◽  
Vol 65 (5) ◽  
pp. 667-670 ◽  
Author(s):  
Ch. Legendre ◽  
V. Garrigue ◽  
C. Le Bihan ◽  
M. F. Mamzer-Bruneel ◽  
M. L. Chaix ◽  
...  

1999 ◽  
Vol 67 (4) ◽  
pp. 556-560 ◽  
Author(s):  
Lionel Rostaing ◽  
Jacques Izopet ◽  
Catherine Arnaud ◽  
Jean-Marc Cisterne ◽  
Laurent Alric ◽  
...  

2012 ◽  
Vol 94 (10S) ◽  
pp. 856
Author(s):  
L. F.C. Giordano ◽  
M. F. Lasmar ◽  
L. F. Lasmar ◽  
A. F. Nogueira ◽  
M. R.O. Santos ◽  
...  

2016 ◽  
Vol 23 (8) ◽  
pp. 1012-1018 ◽  
Author(s):  
Loren Brener ◽  
Courtney von Hippel ◽  
Hannah Wilson ◽  
Max Hopwood

Hepatitis C virus is stigmatised because of its association with injecting drug use. Although treatment is available, uptake remains low, especially among people who inject drugs. Ninety health workers completed a survey assessing attitudes towards people who inject drugs and support for treatment for three client scenarios: one who stopped injecting, one on methadone, and one continuing to inject. Support for hepatitis C virus treatment was significantly higher, where the client was not injecting. Participants who showed more negative attitudes towards people who inject drugs were less supportive of clients entering hepatitis C virus treatment, illustrating the influence of health workers’ attitudes in determining treatment options offered to clients.


2017 ◽  
Vol 9 (3) ◽  
Author(s):  
Genevieve Kerkerian ◽  
Arshia Alimohammadi ◽  
Tyler Raycraft ◽  
Brian Conway

Hepatitis C Virus (HCV) and human immunodeficiency virus (HIV) are global pandemics that affect 170 million and 35 million individuals, respectively. Up to 45% of individuals infected with HCV clear their infections spontaneously – correlating to factors like aboriginal descent and some host specific immune factors. HIV, however, establishes true latency in infected cells and cannot be cured. In the setting of longterm non-progressors (LTNPs) of HIV, a state of immune preservation and low circulating viral load is established. Regarding HIV/HCV co-infection, little is known about the relationship between spontaneous clearance of HCV infection and long-term control of HIV infection without medical intervention. We describe a case of a HIVinfected female defined as a LTNP in whom spontaneous clearance of HCV was documented on multiple occasions. Similar cases should be documented and identified in an effort to develop novel hypotheses about the natural control of these infections and inform research on immune-based interventions to control them.


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