scholarly journals Long-term effect of motor cortex stimulation in patients suffering from chronic neuropathic pain: An observational study

PLoS ONE ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. e0191774 ◽  
Author(s):  
Dylan J. H. A. Henssen ◽  
Erkan Kurt ◽  
Anne-Marie van Cappellen van Walsum ◽  
Inge Arnts ◽  
Jonne Doorduin ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Motor Cortex ◽  
Observational Study ◽  
Term Effect ◽  
Motor Cortex Stimulation ◽  
Chronic Neuropathic Pain ◽  
Long Term Effect

scholarly journals Pre-motor versus motor cerebral cortex neuromodulation for chronic neuropathic pain

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Igor Lavrov ◽  
Timur Latypov ◽  
Elvira Mukhametova ◽  
Brian Lundstrom ◽  
Paola Sandroni ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Cerebral Cortex ◽  
Motor Cortex ◽  
Initial Assessment ◽  
Motor Cortex Stimulation ◽  
Chronic Neuropathic Pain ◽  
Long Term Effect ◽  
Stimulation Of

AbstractElectrical stimulation of the cerebral cortex (ESCC) has been used to treat intractable neuropathic pain for nearly two decades, however, no standardized approach for this technique has been developed. In order to optimize targeting and validate the effect of ESCC before placing the permanent grid, we introduced initial assessment with trial stimulation, using a temporary grid of subdural electrodes. In this retrospective study we evaluate the role of electrode location on cerebral cortex in control of neuropathic pain and the role of trial stimulation in target-optimization for ESCC. Location of the temporary grid electrodes and location of permanent electrodes were evaluated in correlation with the long-term efficacy of ESCC. The results of this study demonstrate that the long-term effect of subdural pre-motor cortex stimulation is at least the same or higher compare to effect of subdural motor or combined pre-motor and motor cortex stimulation. These results also demonstrate that the initial trial stimulation helps to optimize permanent electrode positions in relation to the optimal functional target that is critical in cases when brain shift is expected. Proposed methodology and novel results open a new direction for development of neuromodulation techniques to control chronic neuropathic pain.

scholarly journals Long-term Effect and Predictive Factors of Motor Cortex and Spinal Cord Stimulation for Chronic Neuropathic Pain

2018 ◽  
Vol 58 (10) ◽  
pp. 422-434 ◽  
Author(s):  
Takafumi TANEI ◽  
Yasukazu KAJITA ◽  
Satoshi MAESAWA ◽  
Daisuke NAKATSUBO ◽  
Kosuke AOKI ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Neuropathic Pain ◽  
Motor Cortex ◽  
Predictive Factors ◽  
Spinal Cord Stimulation ◽  
Term Effect ◽  
Chronic Neuropathic Pain ◽  
Long Term Effect

scholarly journals Pre-Motor vs. Motor Cerebral Cortex Neuromodulation For Chronic Neuropathic Pain 

2021 ◽  
Author(s):  
Igor Lavrov ◽  
Timur Latypov ◽  
Elvira Mukhametova ◽  
Brian Lundstrom ◽  
Paola Sandroni ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Cerebral Cortex ◽  
Motor Cortex ◽  
Initial Assessment ◽  
Motor Cortex Stimulation ◽  
Chronic Neuropathic Pain ◽  
Long Term Effect ◽  
Stimulation Of

Abstract Electrical stimulation of the cerebral cortex (ESCC) has been used to treat intractable neuropathic pain for nearly two decades, however, no standardized approach for this technique has been developed. In order to optimize targeting and validate the effect of ESCC before placing the permanent grid, we introduced initial assessment with trial stimulation, using a temporary grid of subdural electrodes. In this retrospective study we evaluate the role of electrode location on cerebral cortex in control of neuropathic pain and the role of trial stimulation in target-optimization for ESCC. Location of the temporary grid electrodes and location of permanent electrodes were evaluated in correlation with the long-term efficacy of ESCC. The results of this study demonstrate that the long-term effect of subdural pre-motor cortex stimulation is at least the same or higher compare to effect of subdural motor or combined pre-motor and motor cortex stimulation. These results also demonstrate that the initial trial stimulation helps to optimize permanent electrode positions in relation to the optimal functional target that is critical in cases when brain shift is expected. Proposed methodology and novel results open a new direction for development of neuromodulation techniques to control chronic neuropathic pain.

Motor cortex stimulation for long-term relief of chronic neuropathic pain: A 10 year experience

Pain ◽  
2006 ◽  
Vol 121 (1) ◽  
pp. 43-52 ◽  
Author(s):  
Dirk Rasche ◽  
Marc Ruppolt ◽  
Christoph Stippich ◽  
Andreas Unterberg ◽  
Volker M. Tronnier
Keyword(s):  
Neuropathic Pain ◽  
Motor Cortex ◽  
Motor Cortex Stimulation ◽  
Chronic Neuropathic Pain

Treatment of chronic neuropathic pain by motor cortex stimulation: Results of a bicentric controlled crossover trial

2008 ◽  
Vol 1 (2) ◽  
pp. 89-96 ◽  
Author(s):  
Jean-Paul Nguyen ◽  
Francisco Velasco ◽  
Pierre Brugières ◽  
Marcos Velasco ◽  
Yves Keravel ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Motor Cortex ◽  
Crossover Trial ◽  
Motor Cortex Stimulation ◽  
Chronic Neuropathic Pain

Long-term effect of safinamide on primary motor cortex excitability and plasticity in Parkinson's disease: A TMS study

2021 ◽  
Vol 429 ◽  
pp. 119453
Author(s):  
Valentina D'Onofrio ◽  
Andrea Guerra ◽  
Francesco Asci ◽  
Giovanni Fabbrini ◽  
Alfredo Berardelli ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Cortex ◽  
Primary Motor Cortex ◽  
Term Effect ◽  
Long Term Effect ◽  
Motor Cortex Excitability

scholarly journals Long-Term Results of a Simultaneous Trial of Deep Brain and Motor Cortex Stimulation in Refractory Neuropathic Pain

2017 ◽  
Vol 3 (1) ◽  
pp. 4-15
Author(s):  
Byung-chul Son ◽  
Jin-gyu Choi ◽  
Sang-woo Ha ◽  
Deog-ryeong Kim
Keyword(s):  
Neuropathic Pain ◽  
Pain Relief ◽  
Motor Cortex ◽  
Success Rate ◽  
Rating Scale ◽  
Long Term Results ◽  
Motor Cortex Stimulation ◽  
Significant Difference ◽  
Deep Brain

Objective Although deep brain stimulation (DBS) and motor cortex stimulation (MCS) are effective in patients with refractory neuropathic pain, their application is still empirical; there is no consensus on which technique is better. Methods To enhance the success rate of trial stimulation of invasive neuromodulation techniques and identify approapriate stimulation targets in individual patients, we performed a simultaneous trial of thalamic ventralis caudalis (Vc) DBS and MCS in 11 patients with chronic neuropathic pain and assessed the results of the trial stimulation and long-term analgesia. Results Of the 11 patients implanted with both DBS and MCS electrodes, nine (81.8%) had successful trials. Seven of these nine patients (77.8%) responded to MCS, and two (18.2%) responded to Vc DBS. With long-term follow-up (56 ± 27.5 months), the mean numerical rating scale decreased significantly (P < 0.05). The degree of percentage pain relief in the chronic MCS (n = 7) and chronic DBS (n = 2) groups were 34.1% ± 18.2% and 37.5%, respectively, and there was no significant difference (P = 0.807). Five out of the seven MCS patients (71%) and both DBS patients had long-term success with the treatments, defined as >30% pain relief compared with baseline. Conclusions With simultaneous trial of DBS and MCS, we could enhance the success rate of invasive trials. Considering the initial success rate and the less invasive nature of epidural MCS over DBS, we suggest that MCS may be a better, initial means of treatment in chronic intractable neuropathic pain. Further investigations including other subcortical target-associated medial pain pathways are warranted.

Motor cortex stimulation for chronic neuropathic pain: a preliminary study of 10 cases

Pain ◽  
2000 ◽  
Vol 84 (2) ◽  
pp. 431-437 ◽  
Author(s):  
Dawn Carroll ◽  
Carole Joint ◽  
Nikki Maartens ◽  
David Shlugman ◽  
John Stein ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Motor Cortex ◽  
Motor Cortex Stimulation ◽  
Chronic Neuropathic Pain ◽  
Preliminary Study
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